Author Archive

Lab on a Chip Thematic collection on cancer immuno-therapy-open for submissions

Professor James R. Heath, Institute for Systems Biology, Seattle, USA

We are very happy to announce a new thematic collection in Lab on a Chip on immunotherapy with Professor James R. Heath, President and Professor at Institute for Systems Biology in Seattle, acting as Thought leader.

In his recent Editorial published in Lab on a Chip, Professor James R. Heath wrote “The rapid development of cancer immunotherapies over the past 5-10 years is not only revolutionizing clinical cancer care, but it is also making the immunotherapy field a proving ground for many new measurement and computational technologies.  An understanding of the technological needs of this field can be gleaned by placing those needs within the context of state-of-the-art treatments. […]

The level of personalisation that is now being tested in the clinic hardly was unthinkable just a decade ago.  The newness of personalized cancer immunotherapies means that, as a rule, they are still extremely expensive.  An urgent and unmet need is to develop technologies that can assist in the democratization of such treatments.[…]

A unique characteristic of the biology of immuno-oncology is that it can invariably be mined to generate new hypotheses for how to improve treatments.  Such hypotheses might include approaches for improved bioengineering of T cells, or the potential identification of new immune checkpoints, etc.  While this characteristic gives cancer immunotherapy a very bright future, it also means that finding technologies that can rapidly and inexpensively validate or negate such hypotheses is an urgent and rapidly expanding need

We welcome primary research and review content relating to how lab-on-a-chip technologies can be developed to address these and related challenges for inclusion in a thematic collection in Lab on a Chip focused on immuno-engineering and immuno-therapy. This collection is now open for submissions and we are looking for submissions into 2020.

Please note that all submitted manuscripts will be subject to peer review in accordance with the journal’s normal standards.

Lab on a Chip publishes significant and original work related to miniaturisation, at the micro- and nano-scale, of interest to a multidisciplinary readership. The journal seeks to publish work at the interface between physical technological advancements and high impact applications that are of direct interest to a broad audience.

We have compiled a collection of recent papers and reviews published in Lab on a Chip on this topic. These articles can be read at https://www.rsc.li/immunotherapy and are available free to access* until the 15th November 2019. A couple of highlights from this collections are shown below.

Graphical Abstract from Segaliny, Zhao, et al., 2018 (DOI: 10.1039/C8LC00818C)


Functional TCR T cell screening using single-cell droplet microfluidics

Aude I. Segaliny, Weian Zhao, et al.

 

MATE-Seq: microfluidic antigen-TCR engagement sequencing

Alphonsus H. C. Ng, James R. Heath et al.

 

If you’re interested in contributing to this collection,

please contact the Lab on a Chip Editorial Office.

 

 

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We are delighted to announce that Hang Lu is the 2019 winner of the “Pioneers of Miniaturization” Lectureship!

The 14th “Pioneers of Miniaturization” Lectureship, sponsored by Dolomite and Lab on a Chip , is for early to mid-career scientists who have made extraordinary or outstanding contributions to the understanding or development of miniaturised systems.

The 2019 “Pioneers of Miniaturization” Lectureship will be presented to Professor Lu at the µTAS 2019 Conference in Basel, Switzerland, being held on 27-31 October 2019. Professor Lu will receive a certificate, a monetary award and will give a short lecture during the conference.

Many congratulations to Professor Hang Lu on this achievement from the Lab on a Chip Team!

About the Winner

Professor Hang Lu is the Love Family Professor, School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, USA.

Professor Lu earned her PhD in Chemical Engineering from Massachusetts Institute of Technology, USA in 2003. After a postdoctoral fellowship with Professor Cornelia I. Bargmann, at University of California San Francisco and the Rockefeller University, she was appointed as an Assistant Professor at School of Chemical and Biomolecular Engineering, Georgia Institute of Technology.

In recognition of her outstanding achievements, Professor Lu has received numerous awards and international recognition, including being invited to join Board of Directors, Chemical and Biological Microsystems Society, invited to present at the Nobel Symposium on Microfluidics (2017) and the National Academy of Sciences’ Kavli Frontiers of Science Symposia (2014, 2012, 2009), awarded the ACS Analytical Chemistry Young Innovator Award, Chemical and Biological Microsystems Society (2013), Council of Systems Biology in Boston (CSB2) Prize in Systems Biology (2011), a National Science Foundation CAREER award (2010), an Alfred P. Sloan Foundation Research Fellowship (2009), a DARPA Young Faculty Award (2007), a DuPont Young Professor Award (2006), the Saville Lectureship of Princeton University (2013), the H. C. Van Ness Award Lectures of Rensselaer Polytechnic Institute (2011), and is a fellow of the American Institute for Medical and Biological Engineering (AIMBE) and  a fellow of the American Association for the Advancement of Science (AAAS). She has authored more than 140 peer-reviewed publications and has served on the Editorial Board of Lab on a Chip as Associate Editor since 2017. She is currently the director of the Interdisciplinary Bioengineering Program, and the associate director of the NSF-Simons Foundation supported Southeast Center for Mathematics and Biology, Georgia Institute of Technology.

Professor Lu has pioneered the use of microfluidic systems for imaging and performing genetic studies with small organisms, primarily the nematode C. elegans. In a series of studies published since 2008 she established a set of technologies to streamline imaging, phenotyping, and sorting of C. elegans based on features that are difficult to distinguish and discern by human eyes. The throughput of these technologies were often 1,000 times that of conventional approaches. Professor Lu’s technology has enable faster and more accurate experiments and revolutionized how genetic screens and high-content imaging experiments are done currently in other scientists’ labs. In parallel, her lab has also engineered micro systems for high-content experiments with cells, aggregates, organoids, and embryos to extract high-dimensional information for systems biology studies.

The Lu group performs research at the interface of engineering and biology. They engineer automated microfluidic systems, microscopy tools, and image imformatic technologies to address questions in neuroscience, cell biology, and biotechnology that are difficult to answer using conventional techniques. Applied to the study of fundamental biological questions, these new techniques allow the Lu group to gather large-scale quantitative data about complex systems.

Learn about the Lu group online

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RSC Analytical Chemistry journals Emerging Investigator Series

Our Analytical Chemistry journals Analyst, Analytical Methods and Lab on a Chip are committed to early career researchers in the analytical chemistry and engineering fields. Our Emerging Investigator Series provide a platform for early career researchers to showcase their best work to a broad audience.

If you have an independent career and are within 10 years of obtaining your PhD or within 5 years of your first independent position you may be eligible for our Analyst, Analytical Methods or Lab on a Chip Emerging Investigator Series.

Analyst Emerging Investigator Series

Series Editors: Ryan Bailey, Laura Lechuga and Jaebum Choo Find out more

Analytical Methods Emerging Investigator Series

Series Editors: Fiona Regan, Juewen Liu and Juan Garcia-Reyes Find out more

Lab on a Chip Emerging Investigator Series

Series Editors: Dino Di Carlo, Yoon-Kyoung Cho and Piotr Garstecki Find out more 

Appropriate consideration will be given to career breaks and alternative career paths.

 

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Lab on a chip – from molecular assays to organs on a chip: a symposium by the Royal Society of Chemistry and ETH Zurich

The Lab on a chip – from molecular assays to organs on a chip symposium will be held on 10th April 2018, Basel, Switzerland. 

The Royal Society of Chemistry journal Lab on a Chip and ETH Zurich are delighted to present this symposium, which will showcase the high impact research from the groups of the Lab on a Chip Editorial Board members. The research presented will be on a wide variety of cutting-edge topics in line with the ethos and scope of the journal.

Editor-in-Chief, Abe Lee, Associate Editor, Petra Dittrich and Executive Editor, Sam Keltie warmly invite you to take part in this event and look forward to welcoming you in Basel.

Final programme

Aims

The symposium will bring together exceptional researchers – all leading names in their field – for an outstanding plenary programme, together with an open lunch for all attendees that will provide many networking opportunities.

Registration

Registration for the event is required, as we have limited spaces at the venue. Registration costs are students & graduate students 20 CHF, postdocs & group leaders: 40 CHF, industry 80 CHF.  Book now

Lunch and coffee

Lunch and coffee are provided and are included with registration.

Venue

Hotel Bildungszentrum 21, Missionsstr. 21, CH – 4055 Basel, Switzerland

 

Contact Information

Dr Sam Keltie

Executive Editor, Lab on a Chip

Royal Society of Chemistry

loc-rsc@rsc.org

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4th Analytical Biosciences Early Career Researcher Meeting

The 4th Analytical Biosciences Early Career Researcher Meeting is the annual meeting organised by the Royal Society of Chemistry Analytical Biosciences Group aimed at engaging with and promoting early career researchers work. This year, it will be held the University of Warwick in Coventry, UK on 15th-16th March. They hope to “engage in discussions and debate through considering applications of the current and future analytical technologies”. Confirmed keynote speakers include Mark Viant, from the University of Birmingham, Pete O’Connor, from the University of Warwick and Matthew Baker, from the University of Strathclyde. To find out more about the programme and to register to attend, please visit their website.


Important Dates:

Abstract Submission Deadline: 1st March 2017

Early Bird Registration Deadline: 31st January 2017

Submit your abstract in order to take advantage of this excellent opportunity to present your work!

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ICAS 2017 – International Congress on Analytical Sciences

ICAS 2017 is the 5 yearly international congress organised by the Chinese Chemical Society (CCS) and the International Union of Pure and Applied Chemistry (IUPAC). The event takes place at the Hainan International Convention and Exhibition Centre in Hainan, China between 5th and 8th May 2017. The theme of this year’s congress is “Analytical Chemistry – From Tool to Science”, which will contain sessions on advanced instrumental analysis, nanoscience and nanotechnology, biological and bioanalysis, environmental sciences, food safety, micro-analysis and microfluidic, sensors systems, mass spectrometry, separation and chromatography, spectrometry/spectroscopy, and electrochemical analysis. The Royal Society of Chemistry Journals Lab on a Chip, Analyst and Analytical Methods are very pleased to be supporting this event.

Visit the conference website for further details on themes and speakers and to submit your abstract.

Important Dates:
Abstract Submission Deadline: 28th February 2017

Early Bird Registration Deadline: 31st March 2017

 Register now to attend and present your work!

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Pioneers of Miniaturisation Lecture 2014 – deadline 30th June!

Miniaturisation plays a significant role in our daily lives; devices are becoming smaller and smaller, and this trend is set to continue. Current micro and nanofluidic research encompasses many scientific developments and technologies that will increase our understanding of phenomena at the micro and nano scale and potentially have a huge positive impact on our lives in the future. The use of micro and nano fluidic technologies will impact on a diverse range of industries ranging from their use in motor cars, through health improvement applications and to their use in protecting national and environmental security needs.

At Lab on a Chip, we strongly believe in this technology and have been willing to show the necessary commitment and financial support to back the development of this research community. It is in this vein we present this award to honour and support the up and coming, next generation pioneers in this field of endeavour. So Lab on a Chip will again join forces with Corning Incorporated to award the ninth ‘Pioneers of Miniaturisation’ Lectureship at µTAS, including a certificate of recognition and a prize of $5000. The lectureship will be presented at the µTAS 2014 Conference in San Antonio, Texas.

Who should you nominate?

The award is for early to mid-career scientists (nominees must be no older than 45 by the closing date for nominations).

The award is for extraordinary or outstanding contributions to the understanding or development of miniaturised systems. This will be judged mainly through their top 1-3 papers and/or an invention documented by patents/or a commercial product. Awards and honorary memberships may also be considered. The awardee is required to give a short lecture at the µTAS Conference in the same year.

The 2013 Pioneers of Miniaturisation Lectureship was awarded to Shuichi Takayama, University of Michigan. 

See here for further information, including past winners.

Nominations to Lab on a Chip Executive Editor Harp Minhas by 30th June

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