Author Archive

Butter substitute reduces blood pressure and cholesterol

Scientists from Finland have shown that a spread containing milk peptides and plant sterols could lower systolic blood pressure and LDL (low density lipoprotein) cholesterol levels.

Cardiovascular disease rates are increasing around the world and its prevention is therefore becoming more pressing, particularly as the disease is typically at an advanced stage when symptoms appear. The spread was developed by Anu Turpeinen at Valio, a company that manufactures dairy products in Helsinki, and colleagues. It offers an economical option in which only a small lifestyle change is required to enjoy the benefits and side-effects are minimal.

The milk peptides are thought to be responsible for the antihypertensive – blood pressure reducing – effects by inhibiting a blood pressure regulator called angiotensin converting enzyme. The lowered LDL cholesterol levels are attributed to the plant sterols preventing intestinal cholesterol absorption, but further research is required on the precise mechanisms of action.

Butter and Milk
The spread combines the blood pressure reducing effect of milk and the cholesterol lowering effect of plant sterols

Read the full article in Chemistry World

Link to journal article
A spread containing bioactive milk peptides Ile–Pro–Pro and Val–Pro–Pro, and plant sterols has antihypertensive and cholesterol-lowering effects
Anu M. Turpeinen ,  Mikko Ikonen ,  Anne S. Kivimäki ,  Hannu Kautiainen ,  Heikki Vapaatalo and Riitta Korpela
Food Funct., 2012, Advance Article, DOI: 10.1039/C2FO10286B

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Healthier sausages

Scientists in Canada have shown that sausages can be made using vegetable oil and a gelling agent instead of animal fat, without altering the texture. With the continual push for healthy eating and eliminating saturated fat from our diets, this novel use of an ethylcellulose organogelator (oleogel) could be applied to substantially reduce the amount of saturated fat in foods.

According to the World Health Organisation, cardiovascular disease is the leading cause of death worldwide and there is evidence that links the disease with high saturated fat consumption. Scientists have been investigating alternatives to hard fats (such as saturated and trans fats) to reduce the risk of cardiovascular disease. But, it is very difficult to find replacements, says lead researcher Alejandro Marangoni from the University of Guelph. ‘You are left with oil, which does not have any structuring ability,’ he adds.

Marangoni’s team made their oleogel using the gelling agent ethylcellulose, a known organogelator for vegetable oils. ‘We had to heat ethylcellulose up quite a bit to go in to triglyceride oils but once that happened, upon cooling, we found that a network formed and we had something almost as hard as a rubber ball!’ says Marangoni.


An oleogel (middle) was used to replace hard fat in a frankfurter. The image on the right is a scanning electron micrograph showing the texture of a soybean oil organogel

Read the full story in Chemistry World

Link to journal article
Mechanical properties of ethylcellulose oleogels and their potential for saturated fat reduction in frankfurters
Alexander K. Zetzl ,  Alejandro G. Marangoni and Shai Barbut
Food Funct., 2012, Advance Article, DOI: 10.1039/C2FO10202A

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Top ten most accessed articles in January

This month sees the following articles in Food & Function that are in the top ten most accessed:-

Nuts, especially walnuts, have both antioxidant quantity and efficacy and exhibit significant potential health benefits
Joe A. Vinson and Yuxing Cai
Food Funct., 2012, Advance Article, DOI: 10.1039/C2FO10152A

Espresso coffees, caffeine and chlorogenic acid intake: potential health implications
Thomas W. M. Crozier, Angelique Stalmach, Michael E. J. Lean and Alan Crozier
Food Funct., 2012, 3, 30-33, DOI: 10.1039/C1FO10240K

Whole grain cereals: functional components and health benefits
Rafael Borneo and Alberto Edel León
Food Funct., 2012, Advance Article, DOI: 10.1039/C1FO10165J

Development of oral food-grade delivery systems: Current knowledge and future challenges
Revital Cohen Benshitrit, Carmit Shani Levi, Sharon Levi Tal, Eyal Shimoni and Uri Lesmes
Food Funct., 2011, Advance Article, DOI: 10.1039/C1FO10068H

Antihypertensive peptides from food proteins: a review
Daniel Martínez-Maqueda, Beatriz Miralles, Isidra Recio and Blanca Hernández-Ledesma
Food Funct., 2012, Advance Article, DOI: 10.1039/C2FO10192K

Surface-active solid lipid nanoparticles as Pickering stabilizers for oil-in-water emulsions
Renuka Gupta and Dérick Rousseau
Food Funct., 2012, Advance Article, DOI: 10.1039/C2FO10203J

The metabolism and analysis of isoflavones and other dietary polyphenols in foods and biological systems
Stephen Barnes, Jeevan Prasain, Tracy D’Alessandro, Ali Arabshahi, Nigel Botting, Mary Ann Lila, George Jackson, Elsa M. Janle and Connie M. Weaver
Food Funct., 2011, 2, 235-244, DOI: 10.1039/C1FO10025D

Mechanisms underlying the cholesterol-lowering properties of soluble dietary fibre polysaccharides
Purnima Gunness and Michael John Gidley
Food Funct., 2010, 1, 149-155, DOI: 10.1039/C0FO00080A

Inhibitory effects of garcinol and pterostilbene on cell proliferation and adipogenesis in 3T3-L1 cells
Chin-Lin Hsu, Yu-Jyun Lin, Chi-Tang Ho and Gow-Chin Yen
Food Funct., 2012, 3, 49-57, DOI: 10.1039/C1FO10209E

Insights into the metabolism and microbial biotransformation of dietary flavan-3-ols and the bioactivity of their metabolites
Maria Monagas, Mireia Urpi-Sarda, Fernando Sánchez-Patán, Rafael Llorach, Ignacio Garrido, Carmen Gómez-Cordovés, Cristina Andres-Lacueva and Begoña Bartolomé
Food Funct., 2010, 1, 233-253, DOI: 10.1039/C0FO00132E

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Making crisps healthier

Crisps

Salt from crisps is only released into the mouth 20 seconds after chewing begins, by which time, the crisp has been swallowed. © Shutterstockd.

An investigation by UK scientists into how salt is released from crisps (known as potato chips in the US) as you eat them could lead to a healthier crisp that tastes just as good.

Ian Fisk and Tian Xing from the University of Nottingham found that a large proportion of the salt in crisps is only released into the mouth 20 seconds after chewing, by which time the crisp may have already been swallowed. Fisk says that this salt burst is underexploited, but it could open doors to salt reduction in snack foods.

Excess salt in the diet has been linked to high blood pressure and cardiovascular disease, so reducing salt in processed foods is a goal for health authorities and food companies alike. ‘Our current aim is to develop a series of technologies that accelerates the delivery of salt to the tongue by moving the “burst” from 20 seconds to within the time that you normally chew and swallow,’ says Fisk. Scientists could then increase the flavour using less salt.

This article has been featured in the UK press (see the Daily Mail and Daily Express stories).

You can hear Ian Fisk talk about the research on BBC Radio 4: listen to the recording here.

 Read the full story in Chemistry World

Link to journal article
Salt release from potato crisps
Xing Tian and Ian D. Fisk
Food Funct., 2012, Advance Article
DOI: 10.1039/C2FO10282J

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Top ten most accessed articles in December

This month sees the following articles in Food & Function that are in the top ten most accessed:-

Espresso coffees, caffeine and chlorogenic acid intake: potential health implications
Thomas W. M. Crozier, Angelique Stalmach, Michael E. J. Lean and Alan Crozier
Food Funct., 2012, 3, 30-33, DOI: 10.1039/C1FO10240K

Whole grain cereals: functional components and health benefits
Rafael Borneo and Alberto Edel León
Food Funct., 2012, Advance Article, DOI: 10.1039/C1FO10165J

Pu-erh tea, green tea, and black tea suppresses hyperlipidemia, hyperleptinemia and fatty acid synthase through activating AMPK in rats fed a high-fructose diet
Hsiu-Chen Huang and Jen-Kun Lin
Food Funct., 2012, Advance Article, DOI: 10.1039/C1FO10157A

Nuts, especially walnuts, have both antioxidant quantity and efficacy and exhibit significant potential health benefits
Joe A. Vinson and Yuxing Cai
Food Funct., 2012, Advance Article, DOI: 10.1039/C2FO10152A

Inhibitory effects of garcinol and pterostilbene on cell proliferation and adipogenesis in 3T3-L1 cells
Chin-Lin Hsu, Yu-Jyun Lin, Chi-Tang Ho and Gow-Chin Yen
Food Funct., 2012, 3, 49-57, DOI: 10.1039/C1FO10209E

Review of the efficacy of green tea, isoflavones and aloe vera supplements based on randomised controlled trials
Gary Williamson, Patrick Coppens, Lluís Serra-Majem and Tristan Dew
Food Funct., 2011, Advance Article, DOI: 10.1039/C1FO10101C

Dietary agents in the prevention of alcohol-induced hepatotoxicty: preclinical observations
Arnadi Ramachandrayya Shivashankara, Aysha Azmidah, Raghavendra Haniadka, Manoj Ponadka Rai, Rajesh Arora and Manjeshwar Shrinath Baliga
Food Funct., 2012, Advance Article, DOI: 10.1039/C1FO10170F

Inhibition of advanced glycation endproduct formation by foodstuffs
Chi-Hao Wu, Shang-Ming Huang, Jer-An Lin and Gow-Chin Yen
Food Funct., 2011, 2, 224-234, DOI: 10.1039/C1FO10026B

Encapsulation of polyphenolic grape seed extract in polymer-coated liposomes
Monika Gibis, Effie Vogt and Jochen Weiss
Food Funct., 2012, Advance Article, DOI: 10.1039/C1FO10181A

Development of oral food-grade delivery systems: Current knowledge and future challenges
Revital Cohen Benshitrit, Carmit Shani Levi, Sharon Levi Tal, Eyal Shimoni and Uri Lesmes
Food Funct., 2011, Advance Article, DOI: 10.1039/C1FO10068H

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All clear for tiny capsules of goodness

Israeli scientists have created nanocapsules based on natural food materials and loaded them with hydrophobic vitamins and other nutraceuticals (health-promoting micronutrients). The nanocapsules can be added to drinks as a health benefit without making them cloudy and they protect the sensitive nutraceuticals from degradation, which have been problems in the past.

Yoav Livney and his team from the Technion, Israel Institute of Technology, in Haifa, used the Maillard reaction to create protein-saccharide conjugate nanocapsules. This natural reaction, which causes the typical browning of food during baking and cooking, has been used to make similar conjugates to encapsulate hydrophobic nutrients, but the resulting capsules were large and turned liquids cloudy.

Vitamin D and epigallocatechin gallate (an antioxidant found in green tea) were loaded into nanocapsules to be added to drinks to deliver health benefits

Read the full story in Chemistry World

Link to journal article
Maillard-conjugate based core–shell co-assemblies for nanoencapsulation of hydrophobic nutraceuticals in clear beverages
Gilad Markman and Yoav D. Livney
Food Funct., 2012, Advance Article, DOI: 10.1039/C1FO10220F

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Top ten most accessed articles in November

This month sees the following articles in Food & Function that are in the top ten most accessed:-

The immediate and short-term chemosensory impacts of coffee and caffeine on cardiovascular activity
Michael K. McMullen, Julie M. Whitehouse, Gillian Shine, Peter A. Whitton and Anthony Towell
Food Funct., 2011, 2, 547-554, DOI: 10.1039/C1FO10102A

Review of the efficacy of green tea, isoflavones and aloe vera supplements based on randomised controlled trials
Gary Williamson, Patrick Coppens, Lluís Serra-Majem and Tristan Dew
Food Funct., 2011, Advance Article, DOI: 10.1039/C1FO10101C

Transcription profiles of LPS-stimulated THP-1 monocytes and macrophages: a tool to study inflammation modulating effects of food-derived compounds
Wasaporn Chanput, Jurriaan Mes, Robert A. M. Vreeburg, Huub F. J. Savelkoul and Harry J. Wichers
Food Funct., 2010, 1, 254-261, DOI: 10.1039/C0FO00113A

(-)-Secoisolariciresinol attenuates high-fat diet-induced obesity in C57BL/6 mice
Shiori Tominaga, Kosuke Nishi, Sogo Nishimoto, Koichi Akiyama, Satoshi Yamauchi and Takuya Sugahara
Food Funct., 2012, Advance Article, DOI: 10.1039/C1FO10166H

Development of oral food-grade delivery systems: Current knowledge and future challenges
Revital Cohen Benshitrit, Carmit Shani Levi, Sharon Levi Tal, Eyal Shimoni and Uri Lesmes
Food Funct., 2011, Advance Article, DOI: 10.1039/C1FO10068H

The importance of the long-chain polyunsaturated fatty acid n-6/n-3 ratio in development of non-alcoholic fatty liver associated with obesity
Rodrigo Valenzuela and Luis A. Videla
Food Funct., 2011, 2, 644-648, DOI: 10.1039/C1FO10133A

Sugar and dietary fibre composition influence, by different hormonal response, the satiating capacity of a fruit-based and a ß-glucan-enriched beverage
Roberta Barone Lumaga, Danilo Azzali, Vincenzo Fogliano, Luca Scalfi and Paola Vitaglione
Food Funct., 2012, Advance Article, DOI: 10.1039/C1FO10065C

Safety assessment of plant food supplements (PFS)
Suzanne J. P. L. van den Berg, Lluis Serra-Majem, Patrick Coppens and Ivonne M. C. M. Rietjens
Food Funct., 2011, Advance Article, DOI: 10.1039/C1FO10067J

An overview of consumer attitudes and beliefs about plant food supplements
Bernadette Egan, Charo Hodgkins, Richard Shepherd, Lada Timotijevic and Monique Raats
Food Funct., 2011, 2, 747-752, DOI: 10.1039/C1FO10109A, Review

Mechanisms of action of isothiocyanates in cancer chemoprevention: an update
Sandi L. Navarro, Fei Li and Johanna W. Lampe
Food Funct., 2011, 2, 579-587, DOI: 10.1039/C1FO10114E

Why not take a look at the articles today and blog your thoughts and comments below.

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Top ten most accessed articles in October

This month sees the following articles in Food & Function that are in the top ten most accessed:-

Review of the efficacy of green tea, isoflavones and aloe vera supplements based on randomised controlled trials
Gary Williamson, Patrick Coppens, Lluís Serra-Majem and Tristan Dew
Food Funct., 2011, Advance Article, DOI: 10.1039/C1FO10101C

The immediate and short-term chemosensory impacts of coffee and caffeine on cardiovascular activity
Michael K. McMullen, Julie M. Whitehouse, Gillian Shine, Peter A. Whitton and Anthony Towell
Food Funct., 2011, 2, 547-554, DOI: 10.1039/C1FO10102A

Mechanisms of action of isothiocyanates in cancer chemoprevention: an update
Sandi L. Navarro, Fei Li and Johanna W. Lampe
Food Funct., 2011, 2, 579-587, DOI: 10.1039/C1FO10114E

Development of oral food-grade delivery systems: Current knowledge and future challenges
Revital Cohen Benshitrit, Carmit Shani Levi, Sharon Levi Tal, Eyal Shimoni and Uri Lesmes
Food Funct., 2011, Advance Article, DOI: 10.1039/C1FO10068H

Transcription profiles of LPS-stimulated THP-1 monocytes and macrophages: a tool to study inflammation modulating effects of food-derived compounds
Wasaporn Chanput, Jurriaan Mes, Robert A. M. Vreeburg, Huub F. J. Savelkoul and Harry J. Wichers
Food Funct., 2010, 1, 254-261, DOI: 10.1039/C0FO00113A

Review of in vitro digestion models for rapid screening of emulsion-based systems
David Julian McClements and Yan Li
Food Funct., 2010, 1, 32-59, DOI: 10.1039/C0FO00111B

Binding of citrus flavanones and their glucuronides and chalcones to human serum albumin
ammad Kamran Khan, Njara Rakotomanomana, Claire Dufour and Olivier Dangles
Food Funct., 2011, 2, 617-626, DOI: 10.1039/C1FO10077G

Botanical species being used for manufacturing plant food supplements (PFS) and related products in the EU member states and selected third countries
Chlodwig Franz, Remigius Chizzola, Johannes Novak and Silvia Sponza
Food Funct., 2011, Advance Article, DOI: 10.1039/C1FO10130G

The importance of the long-chain polyunsaturated fatty acid n-6/n-3 ratio in development of non-alcoholic fatty liver associated with obesity
Rodrigo Valenzuela and Luis A. Videla
Food Funct., 2011, 2, 644-648, DOI: 10.1039/C1FO10133A     

Safety assessment of plant food supplements (PFS)
Suzanne J. P. L. van den Berg, Lluis Serra-Majem, Patrick Coppens and Ivonne M. C. M. Rietjens
Food Funct., 2011, Advance Article, DOI: 10.1039/C1FO10067J

Why not take a look at the articles today and blog your thoughts and comments below.

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Top ten most accessed articles in September

This month sees the following articles in Food & Function that are in the top ten most accessed:-

Natural salicylates: foods, functions and disease prevention
Garry G. Duthie and Adrian D. Wood
Food Funct., 2011, 2, 515-520, DOI: 10.1039/C1FO10128E

Transcription profiles of LPS-stimulated THP-1 monocytes and macrophages: a tool to study inflammation modulating effects of food-derived compounds
Wasaporn Chanput, Jurriaan Mes, Robert A. M. Vreeburg, Huub F. J. Savelkoul and Harry J. Wichers
Food Funct., 2010, 1, 254-261, DOI: 10.1039/C0FO00113A

The immediate and short-term chemosensory impacts of coffee and caffeine on cardiovascular activity
Michael K. McMullen, Julie M. Whitehouse, Gillian Shine, Peter A. Whitton and Anthony Towell
Food Funct., 2011, 2, 547-554, DOI: 10.1039/C1FO10102A

Safety assessment of plant food supplements (PFS)
Suzanne J. P. L. van den Berg, Lluis Serra-Majem, Patrick Coppens and Ivonne M. C. M. Rietjens
Food Funct., 2011, Advance Article, DOI: 10.1039/C1FO10067J

Dietary chromones as antioxidant agents—the structural variable

M. M. Dias, N. F. L. Machado and M. P. M. Marques
Food Funct., 2011, 2, 595-602, DOI: 10.1039/C1FO10098J

Weight loss and metabolic profiles in obese individuals using two different approaches
Irene A. Munro and Manohar L. Garg
Food Funct., 2011, 2, 611-616, DOI: 10.1039/C1FO10143A

Review of the efficacy of green tea, isoflavones and aloe vera supplements based on randomised controlled trials
Gary Williamson, Patrick Coppens, Lluís Serra-Majem and Tristan Dew
Food Funct., 2011, Advance Article, DOI: 10.1039/C1FO10101C

Insights into the metabolism and microbial biotransformation of dietary flavan-3-ols and the bioactivity of their metabolites
Maria Monagas, Mireia Urpi-Sarda, Fernando Sánchez-Patán, Rafael Llorach, Ignacio Garrido, Carmen Gómez-Cordovés, Cristina Andres-Lacueva and Begoña Bartolomé
Food Funct., 2010, 1, 233-253, DOI: 10.1039/C0FO00132E

Anti-inflammatory activity of natural dietary flavonoids
Min-Hsiung Pan, Ching-Shu Lai and Chi-Tang Ho
Food Funct., 2010, 1, 15-31, DOI: 10.1039/C0FO00103A, Review

Influence of antioxidant rich fresh vegetable juices on starch induced postprandial hyperglycemia in rats
Ashok K. Tiwari, K. Srikanth Reddy, Janani Radhakrishnan, D. Anand Kumar, Amtul Zehra, Sachin B. Agawane and K. Madhusudana
Food Funct., 2011, 2, 521-528, DOI: 10.1039/C1FO10093A

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Top ten most accessed articles in August

This month sees the following articles in Food & Function that are in the top ten most accessed:-

Transcription profiles of LPS-stimulated THP-1 monocytes and macrophages: a tool to study inflammation modulating effects of food-derived compounds
Wasaporn Chanput, Jurriaan Mes, Robert A. M. Vreeburg, Huub F. J. Savelkoul and Harry J. Wichers
Food Funct., 2010, 1, 254-261, DOI: 10.1039/C0FO00113A

Anti-inflammatory activity of natural dietary flavonoids
Min-Hsiung Pan, Ching-Shu Lai and Chi-Tang Ho
Food Funct., 2010, 1, 15-31, DOI: 10.1039/C0FO00103A, Review

Safety assessment of plant food supplements (PFS)
Suzanne J. P. L. van den Berg, Lluis Serra-Majem, Patrick Coppens and Ivonne M. C. M. Rietjens
Food Funct., 2011, Advance Article, DOI: 10.1039/C1FO10067J

Bioactive peptides derived from milk proteins and their health beneficial potentials: an update
Ravinder Nagpal, Pradip Behare, Rajiv Rana, Ashwani Kumar, Manoj Kumar, Sanu Arora, Fransesco Morotta, Shalini Jain and Hariom Yadav
Food Funct., 2011, 2, 18-27, DOI: 10.1039/C0FO00016G

Review of in vitro digestion models for rapid screening of emulsion-based systems
David Julian McClements and Yan Li
Food Funct., 2010, 1, 32-59, DOI: 10.1039/C0FO00111B

Development of a simple model device for in vitro gastric digestion investigation
Jianshe Chen, Vishwajeet Gaikwad, Melvin Holmes, Brent Murray, Malcolm Povey, Ye Wang and Ying Zhang
Food Funct., 2011, 2, 174-182, DOI: 10.1039/C0FO00159G

Conjugated quercetin glucuronides as bioactive metabolites and precursors of aglycone in vivo
Junji Terao, Kaeko Murota and Yoshichika Kawai
Food Funct., 2011, 2, 11-17, DOI: 10.1039/C0FO00106F

Effects of O-methylated metabolites of quercetin on oxidative stress, thermotolerance, lifespan and bioavailability on Caenorhabditis elegans
Felipe Surco-Laos, Juan Cabello, Eva Gómez-Orte, Susana González-Manzano, Ana M. González-Paramás, Celestino Santos-Buelga and Montserrat Dueñas
Food Funct., 2011, 2, 445-456, DOI: 10.1039/C1FO10049A

Red wine: A source of potent ligands for peroxisome proliferator-activated receptor γ
Alfred Zoechling, Falk Liebner and Alois Jungbauer
Food Funct., 2011, 2, 28-38, DOI: 10.1039/C0FO00086H

The metabolism and analysis of isoflavones and other dietary polyphenols in foods and biological systems
Stephen Barnes, Jeevan Prasain, Tracy D’Alessandro, Ali Arabshahi, Nigel Botting, Mary Ann Lila, George Jackson, Elsa M. Janle and Connie M. Weaver
Food Funct., 2011, 2, 235-244, DOI: 10.1039/C1FO10025D

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Food & Function? Then why not submit to us today or alternatively email us your suggestions.

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