Top ten most accessed articles in April

This month sees the following articles in Analytical Methods that are in the top ten most accessed:-

Anatase TiO2 nanoparticle–graphene nanocomposites: One-step preparation and their enhanced direct electrochemistry of hemoglobin 
Qingming Shen ,  Shiwei Zhou ,  Xiaomei Zhao ,  Li-Ping Jiang ,  Wenhua Hou and Jun-Jie Zhu  
Anal. Methods, 2012,4, 619-622 DOI: 10.1039/C2AY05781F  

Capacitively coupled contactless conductivity detection on microfluidic systems—ten years of development 
Wendell Karlos Tomazelli Coltro ,  Renato Sousa Lima ,  Thiago Pinotti Segato ,  Emanuel Carrilho ,  Dosil Pereira de Jesus ,  Claudimir Lucio do Lago and José Alberto Fracassi da Silva  
Anal. Methods, 2012,4, 25-33 DOI: 10.1039/C1AY05364G  

A graphene oxide–rhodamine 6G nanocomposite as turn-on fluorescence probe for selective detection of DNA 
Xue Wang ,  Shuhua Zhong ,  Yu He and Gongwu Song  
Anal. Methods, 2012,4, 360-362 DOI: 10.1039/C2AY05827H

Detection of apoptosis: A review of conventional and novel techniques 
Michelle M. Martinez ,  Randall D. Reif and Dimitri Pappas  
Anal. Methods, 2010,2, 996-1004 DOI: 10.1039/C0AY00247J  

Simultaneous UV/Vis spectroscopy and surface enhanced Raman scattering of nanoparticle formation and aggregation in levitated droplets 
Jonas Schenk ,  Lisa Tröbs ,  Franziska Emmerling ,  Janina Kneipp ,  Ulrich Panne and Merwe Albrecht  
Anal. Methods, 2012,4, 1252-1258 DOI: 10.1039/C2AY05744A  

Polyaniline/polyacrylic acid/multi-walled carbon nanotube modified electrodes for sensing ascorbic acid 
Ida Tiwari ,  Karan Pratap Singh ,  Manorama Singh and Craig E. Banks  
Anal. Methods, 2012,4, 118-124 DOI: 10.1039/C1AY05415E  

G-quadruplex fluorescence quenching ability: a simple and efficient strategy to design a single-labeled DNA probe 
Xiaohai Yang ,  Ying Zhu ,  Pei Liu ,  Leiliang He ,  Qingzhao Li ,  Qing Wang ,  Kemin Wang ,  Jin Huang and Jianbo Liu  
Anal. Methods, 2012,4, 895-897 DOI: 10.1039/C2AY25034A  

Electrochemiluminescence based on quantum dots and their analytical application 
Haiping Huang ,  Jingjing Li and Jun-Jie Zhu  
Anal. Methods, 2011,3, 33-42 DOI: 10.1039/C0AY00608D 

Copper-promoted probe for nitric oxide based on o-phenylenediamine: Large blue-shift in absorption and fluorescence enhancement 
Xiaolong Sun ,  Yufang Xu ,  Weiping Zhu ,  Chunsheng He ,  Lin Xu ,  Youjun Yang and Xuhong Qian 
Anal. Methods, 2012,4, 919-922 DOI: 10.1039/C2AY25039J  

Let there be chip—towards rapid prototyping of microfluidic devices: one-step manufacturing processes 
Ansgar Waldbaur ,  Holger Rapp ,  Kerstin Länge and Bastian E. Rapp  
Anal. Methods, 2011,3, 2681-2716 DOI: 10.1039/C1AY05253E  

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Analytical Methods? Then why not submit to us today or alternatively email us your suggestions.

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HOT Article: Biomagnetic glass beads for SERS analysis

Zhao et al., Anal. Methods, 2012, Advance Article

Bing Zhao and Yukihiro Ozaki from Jilin University and Kwansei Gakuin University, respectively, have together with colleagues developed a novel surface-enhanced Raman scattering (SERS)-based detection method for proteins using magnetic glass beads. Target proteins or molecules with a specially recognized feature can be captured and separated by the magnetic nanoparticles. Click on the title below to read more about this new method.

Biomagnetic glass beads for protein separation and detection based on surface-enhanced Raman scattering
Lei Chen, Xiao Xia Han, Zhinan Guo, Xu Wang, Weidong Ruan, Wei Song, Bing Zhao and Yukihiro Ozaki
Anal. Methods, 2012, Advance Article
DOI: 10.1039/C2AY25244A

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Chemometrics in analytical science

Used particularly heavily in analytical chemistry and metabolomics, ‘chemometrics’ is the science of using mathematical or statistical methods to extract information from a chemical system. Beginning in the 1970s with the emergence of computer driven scientific investigation, chemometrics frequently uses methods found in applied mathematics, computer science and statistics.

Analytical Methods presents an excellent forum for such work, and below is a sample of the high-quality work we have published in this area.  These articles are free to access until 21st June 2012 so make the most of this opportunity and take a look!

Determination of flavor components of rice bran by GC-MS and chemometrics
Maomao Zeng, Liangxiao Zhang, Zhiyong He, Fang Qin, Xueyan Tang, Xiaolin Huang, Honghong Qu and Jie Chen
Anal. Methods, 2012, 4, 539-545
DOI: 10.1039/C2AY05671B

Rapid measurement of antioxidant activity in dark soy sauce by NIR spectroscopy combined with spectral intervals selection and nonlinear regression tools
Qin Ouyang, Jiewen Zhao, Quansheng Chen, Hao Lin and Zongbao Sun
Anal. Methods, 2012, 4, 940-946
DOI: 10.1039/C2AY05766B

Quantitative monitoring of the progress of organic reactions using multivariate image analysis-thin layer chromatography (MIA-TLC) method
Bahram Hemmateenejad, Morteza Akhond, Zahra Mohammadpour and N. Mobaraki
Anal. Methods, 2012, 4, 933-939
DOI: 10.1039/C2AY25023C

Multi-response optimization of sequential injection chromatographic method for determination of lisinopril and hydrochlorothiazide
Abubakr M. Idris, Salih A. Naheid, Rafea E. E. Elgorashe, Mohamed A. H. Eltayeb and Ahmed O. Alnajjar
Anal. Methods, 2012, Advance Article
DOI: 10.1039/C2AY05876F

Application of multiway-variate calibration to simultaneous voltammetric determination of three catecholamines
Yongnian Ni, Yi Gui and Serge Kokot
Anal. Methods, 2011, 3, 385-392
DOI: 10.1039/C0AY00445F

Multivariate calibration methods in near infrared spectroscopic analysis
Xueguang Shao, Xihui Bian, Jingjing Liu, Min Zhang and Wensheng Cai
Anal. Methods, 2010, 2, 1662-1666
DOI: 10.1039/C0AY00421A

Trends in process analytical technology
Wee Chew and Paul Sharratt
Anal. Methods, 2010, 2, 1412-1438
DOI: 10.1039/C0AY00257G

Measuring estriol and estrone simultaneously in liquid cosmetic samples using second-order calibration coupled with excitation–emission matrix fluorescence based on region selection
De-Zhu Tu, Hai-Long Wu, Yuan-Na Li, Juan Zhang, Yong Li, Chong-Chong Nie, Xiao-Hua Zhang and Ru-Qin Yu
Anal. Methods, 2012, 4, 222-229
DOI: 10.1039/C1AY05388D

Classification of polymer groups by means of a new polymer testing instrument, the identiPol QA, coupled with pattern recognition techniques
Bozena M. Lukasiak and John C. Duncan
Anal. Methods, 2010, 2, 1948-1957
DOI: 10.1039/C0AY00498G

A simple kinetic spectrophotometric method for simultaneous determination of tetracyclines by use of chemometrics
Yongnian Ni, Na Deng and Serge Kokot
Anal. Methods, 2010, 2, 1302-1309
DOI: 10.1039/C0AY00213E

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HOT Article: Cling film forensics!

A quantitative assessment of the chemical variation in food grade polyethylene cling film, a common wrapping material for illicit drugs, using attenuated total reflection-Fourier transform infrared spectroscopy

Holman et al., Anal. Methods, 2012, Advance Article

Forensic investigators often encounter cling film as a wrapping for illicit drugs. Using attenuated total reflection-Fourier transform infrared spectroscopy (ATR-FTIR) Stephen W. Holman and colleagues from Anglia Ruskin University, Cambridge, UK, have been studying the level of the chemical variation in food grade low-density polyethylene (LDPE) cling film. Click on the below title to read more about their research.

A quantitative assessment of the chemical variation in food grade polyethylene cling film, a common wrapping material for illicit drugs, using attenuated total reflection-Fourier transform infrared spectroscopy
Stephen W. Holman, Trevor F. Emmett and Michael D. Cole
Anal. Methods, 2012, Advance Article
DOI: 10.1039/C2AY05889H

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HOT Article: Evaluating encapsulation of nanomaterials

Statistical analysis of discrete encapsulation of nanomaterials in colloidal capsules

Yomo et al., Anal. Methods, 2012, Advance Article

Tetsuya Yomo and colleagues from Osaka University, Japan, have proposed a measurement and analysis method of discrete encapsulation of nanomaterials in colloidal capsules, in volumes of fL to pL, using fluorescence flow cytometry. The technique could be of great help in the molecular design of intrinsically heterogeneous microcapsules and vesicles. These microcapsules are important for applications that include drug carriers, catalyst reactions, and model cell studies. Click on the title below to read more.

Statistical analysis of discrete encapsulation of nanomaterials in colloidal capsules
Tatsuya Sakakura, Kazuya Nishimura, Hiroaki Suzuki and Tetsuya Yomo
Anal. Methods, 2012, Advance Article
DOI: 10.1039/C2AY25105A

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HOT articles in Issue 5

Formation and aggregation of silver nanoparticles in acoustically levitated droplets were investigated by simultaneous UV/Vis and Raman spectroscopy measurements.

Schenk et al., Anal. Methods, 2012, 4, 1252-1258

Have you seen the HOT papers in the latest issue of Analytical Methods?  Some of the interesting applications featured include analysing works of art, detection of bromate in drinking water, and extracting arsenic from rice.

There’s also a paper from Editorial Board member Ulrich Panne and colleagues (right) on the formation and aggregation of silver nanoparticles in acoustically levitated droplets investigated by simultaneous UV/Vis and Raman spectroscopy.

All these HOT papers will be free to access until 22 May.

Read more »

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Issue 5 now online

Analytical Methods, 2012, Vol 4, Issue 5, front cover

Linck et al., Anal. Methods, 2012, 4, 1215-1220

Take a look at the latest issue of Analytical Methods, complete with two striking covers (if we do say so ourselves).

The front cover highlights work from Ute Resch-Genger of BAM Federal Institute for Materials Research and Testing, Berlin and his collaborators from across Germany.  They have established an improved signal amplification protocol for biological assays using rolling circle amplification RCA, direct enzymatic labeling and the potential Cy3-substitute DY-555.  The authors say their straightforward detection protocol can be applied to many other assay formats using a DNA primer to improve their detection limits, such as immunoassays, and that the strategy could be attractive for point-of-care diagnostics.

Direct labeling rolling circle amplification as a straightforward signal amplification technique for biodetection formats
Lena Linck, Edda Reiß, Frank Bier and Ute Resch-Genger
Anal. Methods, 2012, 4, 1215-1220
DOI: 10.1039/C2AY05760C

Featured on the inside front cover is a communication from Erqun Song, Yang Song and their colleagues from Southwest University, Chongqing, China.  They report the one-step synthesis of N-acetylglucosamine-functionalized gold nanoparticle (NAG–AuNP), which then served as a facile, economic, highly sensitive and selective sensor for the detection of lectin from wheat germ, based on colorimetric and resonance light scattering signals.  The authors expect that their new nanoparticles could be adapted for many applications in the future.

Analytical Methods, 2012, Vol 4, Issue 5, inside front cover

Song et al., Anal. Methods, 2012, 4, 1199-1201

Communication: One-step facile synthesis of N-acetylglucosamine-functionalized gold nanoparticles for direct visual and light-scattering detection of lectin from wheat germ
Erqun Song, Jingrong Li, Hong Wei and Yang Song
Anal. Methods, 2012, 4, 1199-1201
DOI: 10.1039/C2AY25209K

These cover articles will be free to access for 6 weeks, and don’t forget to take a look at the HOT papers in this issue too.

Follow Analytical Methods on Twitter: @methodsrsc

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Analytical methods in traditional medicines

Traditional medicinesMore and more lately we are finding that the traditional medicines from the past have medicinal qualities that can fight modern diseases and medical conditions. A lot of research is now being directed at studying traditional herbs and medicines for bioactive compounds in an attempt to find new treatments.

Analytical Methods presents an excellent forum for such work, and below is a sample of the high-quality work we have published in this area.  These articles are free to access until 31st May 2012 so make the most of this and take a look!

Application of ionic liquids in the microwave-assisted extraction of quercetin from Chinese herbal medicine
Xiaojie Liu, Yuzhi Wang, Jinhuan Kong, Chan Nie and Xiao Lin
Anal. Methods, 2012, 4, 1012-1018, DOI: 10.1039/C2AY05834K

A supersensitive sensor for rutin detection based on multi-walled carbon nanotubes and gold nanoparticles modified carbon paste electrodes
Jing Zhou, Kai Zhang, Jie Liu, Ge Song and Baoxian Ye
Anal. Methods, 2012, Advance Article, DOI: 10.1039/C2AY05930D

Screening target components from Radix salviae miltiorrhiae using an EGFR/CMC-online-HPLC/MS method
Sheng-Li Han, Tao Zhang, Jing Huang, Zhi-Gang Hu and Si-Cen Wang
Anal. Methods, 2012, 4, 1078-1083, DOI: 10.1039/C2AY05857J

Study on the separation mechanism of 1-phenyl-3-methyl-5-pyrazolone derivatives of aldoses in acid buffer by capillary zone electrophoresis
Huaizhong Guo, Wenyue Jiang, Xiaomin Pang, Fang Wu and Fangli Liu
Anal. Methods, 2012, 4, 265-269, DOI: 10.1039/C1AY05645J

Chromatographic fingerprint of Semen Armeniacae Amarae based on high-performance liquid chromatogram and chemometric methods
Qin Lv, Lun-Zhao Yi, Hai-Yang Yi and Yi-Zeng Liang
Anal. Methods, 2012, 4, 299-308, DOI: 10.1039/C1AY05345K

Chinese traditional medicinesCharacterization of flavone glycosides and aglycones in Cephalotaxus sinensis by HPLC-DAD-MS
Yongqian Zhang, Zhihui Xu and Yulin Deng
Anal. Methods, 2011, 3, 1386-1391, DOI: 10.1039/C1AY05098B

Development and characterization of molecularly imprinted polymer microspheres for the selective detection of kaempferol in traditional Chinese medicines
Hongbin Zhu, Yuzhi Wang, Ya Yuan and Huan Zeng
Anal. Methods, 2011, 3, 348-355, DOI: 10.1039/C0AY00578A

Determination of strychnine in strychnos nux-vomica crude and detoxified seeds by voltammetric method using a carbon paste electrode incorporated with gold nanoparticles
Mohsen Behpour, Sayed Mehdi Ghoreishi, Maryam Khayatkashani and Mohamadhasan Motaghedifar
Anal. Methods, 2011, 3, 872-876, DOI: 10.1039/C0AY00658K

Similarity analysis between cultivars of litchi (Litchi chinensis Sonn.) leaf by structural characteristics of polysaccharides
Yeyuan Chen, Haiyan Luo, Min Zhu and Aiping Gao
Anal. Methods, 2010, 2, 1456-1460, DOI: 10.1039/C0AY00315H

Rapid determination of six kavalactones in kava root and rhizome samples using Fourier transform infrared spectroscopy and multivariate analysis in comparison with gas chromatography
Jun Wang, Weiyue Qu, Soojin Jun, Harry C. Bittenbender and Qing X. Li
Anal. Methods, 2010, 2, 492-498, DOI: 10.1039/C0AY00021C

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Gordon F. Kirkbright Bursary Award 2013 announced

Gordon F. Kirkbright Bursary AwardThe Gordon F. Kirkbright bursary award is a prestigious annual award that enables a promising student/non-tenured young scientist of any nation to attend a recognised scientific meeting or visit a place of learning.
The fund for this bursary was established in 1985 as a memorial to Professor Gordon Kirkbright in recognition of his contributions to analytical spectroscopy and to science in general. Although the fund is administered by the Association of British Spectroscopists (ABS) Trust, the award is not restricted to spectroscopists.

Applications are invited for the 2013 Gordon Kirkbright Bursary.

For further information contact John Chalmers at, email: vibspecconsult@aol.com

The closing date for entries is 31 December 2012.

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Deadline extended for Tomas A. Hirschfeld and FACSS Student Awards

SCIX 2012TOMAS A. HIRSCHFELD AND FACSS STUDENT AWARDS – Deadline extended to May 15, 2012.

These awards recognize the most outstanding papers submitted to the conference by a graduate student. Recipients will receive economy travel to the meeting, complimentary registration, and complimentary hotel accommodations.  In order to be considered for designation as a Tomas A. Hirschfeld or FACSS Student Award, the student must submit a presentation for the SCIX 2012 conference, just as any other technical presentation is submitted.  The submission must be a bona fide paper to be presented at SCIX.  For consideration for this award the student must complete the submission form on the FACSS website and in addition submit the following:

  • a 250 word abstract of the work to be reported.
  • two letters of nomination, one by the student’s mentor.
  • a copy of the candidates resumé.
  • a copy of the candidate’s graduate transcript.
  • copies of reprints and/or preprints of research accomplished.
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