Archive for the ‘Hot Article’ Category

HOT article: Determination of amino acids and amines in mammalian decomposition fluid

Swann et al, 2011Professor Simon Lewis and colleagues from Curtin University, Perth, Australia have developed a sensitive and selective analytical method utilising liquid chromatography-electrospray ionisation-tandem mass spectrometry (LC-ESI-MS/MS) operated in multiple reaction monitoring mode for the semi-quantitative determination of 19 biogenic amines and amino acids in mammalian (porcine) decomposition fluid.

The study of mammalian soft tissue decomposition is an emerging area in forensic science. An understanding of this process is extremely important for investigations of suspicious deaths as it complicates determination of cause of death and makes the estimation of postmortem interval (PMI) very difficult. The first step to understanding this chemistry is identifying the compounds present in decomposition fluid and determining when they are produced.

Determination of amino acids and amines in mammalian decomposition fluid by direct injection liquid chromatography-electrospray ionisation-tandem mass spectrometry
Lisa M. Swann, Francesco Busetti and Simon W. Lewis
Anal. Methods, 2012, Advance Article
DOI: 10.1039/C1AY05447C

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)

Thermoresponsive polymers in liquid chromatography

Maria-Magdalena Titirici and colleagues have looked into the recent advances in thermoresponsive liquid chromatography which have allowed separation of biomolecule mixtures using aqueous solvents under isocratic conditions.  This mini-review covers investigations into thermoresponsive polymer stationary phases and looks into the broader view and perspectives of the field.

This article is free to access until 21st November 2011!  Click on the link below to read more…

Thermoresponsive polymers in liquid chromatography, Irene Tan, Farnoosh Roohi and Maria-Magdalena Titirici, Anal. Methods, 2011, DOI: 10.1039/C1AY05356F

You may also be interested in these liquid chromatography papers…

Fast analysis of flavonoids in apple juice on new generation halo column by SPE-HPLC, Imran Ali, Salma M. Z. Al-kindy, Fakhreldin O. Suliman and Syed Dilshad Alam, Anal. Methods, 2011, DOI: 10.1039/C1AY05496A

Successful characterization of degradation products of drugs using LC-MS tools: Application to piroxicam and meloxicam, Dattatray T. Modhave, Tarun Handa, Ravi P. Shah and Saranjit Singh, Anal. Methods, 2011, DOI: 10.1039/C1AY05493G

Fast and sensitive determination of aluminium with RP-HPLC using an ultra-short monolithic column, Tomas A. Remenyi, Pavel N. Nesterenko, Andrew R. Bowie, Edward C. V. Butler and Paul R. Haddad, Anal. Methods, 2011, DOI: 10.1039/C1AY05192J

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)

Take a look at Issue 10

Analytical Methods, 2011, Issue 10 front cover

Analytical Methods, 2011, 3(10): 2167-2426

On the cover of the latest issue of Analytical Methods is a minireview from Kate Griffiths and colleagues at the Australian National Measurement Institute.

When using quantitative PCR, a calibration curve is commonly constructed from serial dilution of a reference DNA preparation and the test material is quantified by comparison to the curve.  There are many factors in this process that can affect the accuracy of the measured value, and there have been some efforts to standardise or optimise this technique as there is ample evidence of measurement inconsistencies.

Here, Griffiths et al. present a relatively simple process for estimating measurement uncertainty for quantitative DNA measurements produced by qPCR, with a worked example.

Quantitative polymerase chain reaction: a framework for improving the quality of results and estimating uncertainty of measurement
Kate R. Griffiths, Daniel G. Burke and Kerry R. Emslie
Anal. Methods, 2011, 3, 2201-2211
DOI: 10.1039/C1AY05069A

This article will be free for 6 weeks.

Chew and Sharratt, Anal. Methods, 2010, 2, 1412-1438You may also be interested in this review:

Critical Review: Trends in process analytical technology
Wee Chew and Paul Sharratt
Anal. Methods, 2010, 2, 1412-1438
DOI: 10.1039/C0AY00257G

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)

Fast and sensitive detection of aluminium with RP-HPLC

Scientists from Australia have developed a method for the fast and sensitive detection of aluminium in aqueous samples via reversed-phased high-performance liquid-chromatography (RP-HPLC) using an ultra-short monolithic column.

The team led by Pavel Nesterenko demonstrated that a ‘run time’ of 2.5 min could be achieved for this method without compromising sensitivity, precision or accuracy, representing an improvement in run time by more than 50% compared to the fasted method published previously.

Read the paper for free until 4th November 2011!

Fast and sensitive determination of aluminium with RP-HPLC using an ultra-short monolithic column, Tomas A. Remenyi, Pavel N. Nesterenko, Andrew R. Bowie, Edward C. V. Butler and Paul R. Haddad, Anal. Methods, 2011, DOI: 10.1039/C1AY05192J

You may also find these chromatography papers interesting……

Determination of estrogens in environmental water samples with solid-phase extraction packed with bamboo charcoal prior to high-performance liquid chromatography-ultraviolet detection, Jia-Bin Zhou, Cong Hu and Ru-Song Zhao, Anal. Methods, 2011, DOI: 10.1039/C1AY05453H

Chromatographic determination of active compounds in topical formulations, Ludmila Matysová, Petra Koblová, Lubomír Galla, Hana Sklenářová, Lucie Havlíková and Petr Solich, Anal. Methods, 2011, DOI: 10.1039/C1AY05336A

Three-phase hollow fiber microextraction based on carrier-mediated transport combined with HPLC-UV for the analysis of dexamethasone sodium phosphate in biological samples, Homeira Ebrahimzadeh, Yadollah Yamini, Katayoun Mahdavi Ara and Fahimeh Kamarei, Anal. Methods, 2011, 3, 2095-2101, DOI: 10.1039/C1AY05207A

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)

Issue 9 online

Issue 9 front cover: Gregson et al.

In the latest issue of Analytical Methods, three articles are highlighted on the covers.

On the front cover is work from Robin Taylor and colleagues of the National Nuclear Laboratory, at various sites across the UK.

There are a number of nuclear legacy fuel storage ponds and silos in the UK that contain substantial volumes of corroding spent Magnox fuel pieces.  Understanding the nature and behaviour of the radionuclides in the ponds, including any potential for activity transfer from solid to solution phases, is critical in the environmental clean-up of these nuclear legacy facilities.  The results presented in this paper indicate that Pu redox chemistry, and therefore solubility, varies across the pond, which has implications for Pu behaviour during waste processing.

Inside front cover: Tsukagoshi et al.

Characterisation of plutonium species in alkaline liquors sampled from a UK legacy nuclear fuel storage pond
Colin R. Gregson, Jeremy J. Hastings, Howard E. Sims, Helen M. Steele and Robin J. Taylor
Anal. Methods, 2011, 3, 1957-1968
DOI: 10.1039/C1AY05313B

Work from Toshihiro Fujii of Meisei University and colleagues is shown on the inside front cover.

They investigated the thermal decomposition of Japanese lacquer liquid and films by means of evolved gas analysis-ion attachment mass spectrometry.  Their results indicated two stages of water release, vaporization and intramolecular H2O elimination, and the kinetics of these two processes were studied.

Characterization of Japanese lacquer liquid and films by means of evolved gas analysis-ion attachment mass spectrometry
Masamichi Tsukagoshi, Yuki Kitahara, Seiji Takahashi, Takahisa Tsugoshi and Toshihiro Fujii
Anal. Methods, 2011, 3, 1943-1947
DOI: 10.1039/C1AY05215B

Back cover: Hoa and El-Safty

On the back cover, Sherif A. El-Safty and Nguyen Duc Hoa of the National Institute for Materials Science introduce the use of highly ordered mesoporous silica/metal oxide nanocomposite monoliths for volatile organic compound gas sensor applications.

Highly sensitive and selective volatile organic compound gas sensors based on mesoporous nanocomposite monoliths
Nguyen Duc Hoa and Sherif A. El-Safty
Anal. Methods, 2011, 3, 1948-1956
DOI: 10.1039/C1AY05333G

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)

Recognition of counterfeit medicines by near-infrared spectroscopy

Principal component analysis and multivariate image analysis were used to analyse the data.

Principal component analysis and multivariate image analysis were used to analyse the data.

Sulaf Assi and colleagues have developed a non-destructive method combining chemometrics and near-infrared spectroscopy to identify potential counterfeit medicines.

Read the paper for free until 7th October.

Identification of counterfeit medicines from the Internet and the World market using near-infrared spectroscopy
Sulaf Assi, Robert A. Watt and Anthony C. Moffat
Anal. Methods
DOI: 10.1039/C1AY05227F

You might also find these near infrared spectroscopy papers interesting…

Classification of vinegar samples based on near infrared spectroscopy combined with wavelength selection
Wei Fan, Hongdong Li, Yang Shan, Huiying Lv, Huaxiu Zhang and Yizeng Liang
Anal. Methods, 2011, 3, 1872-1876
DOI: 10.1039/C1AY05101F

Simultaneous determination of phenol and p-nitrophenol in wastewater using near-infrared diffuse reflectance spectroscopy with adsorption preconcentration
Yan Zhang, Yong Hao, Wensheng Cai and Xueguang Shao
Anal. Methods, 2011, 3, 703-708
DOI: 10.1039/C0AY00775G

Remote identification of chemicals concealed behind clothing using near infrared spectroscopy
Céline M. Canal, Aamer Saleem, Roger J. Green and David A. Hutchins
Anal. Methods, 2011, 3, 84-91
DOI: 10.1039/C0AY00386G

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)

Issue 8 cover articles

Analytical Methods, 2011, 3(8): 1695-1914

Did you catch the happy cover for Issue 8?

The rather smiley picture on the front cover highlights a review by Sangeeta Tanna and Graham Lawson of De Montfort University on the analytical methods used in conjunction with dried blood spots. Access this article for free using the link below:

Critical Review: Analytical methods used in conjunction with dried blood spots
Sangeeta Tanna and Graham Lawson
Anal. Methods, 2011, 3, 1709-1718
DOI: 10.1039/C1AY05160

The back cover features work from Amina Woods of the National Institute on Drug Abuse, NIH on the use of MALDI-MS lipid imaging in rat brain tissue.

Communication: Highlighting anatomical sub-structures in rat brain tissue using lipid imaging
Alice M. Delvolve, Benoit Colsch and Amina S. Woods
Anal. Methods, 2011, 3, 1729-1736
DOI: 10.1039/C1AY05107E

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)

Lectin-gold nanoparticle conjugate could aid understanding of relationship between cellular glycosylation machinery and cell function

Covalent coupling of proteins with gold nanoparticles creates robust and stable probes.

Scientists from China have synthesised a lectin-gold nanoparticle conjugate which can be used as an optical probe for evaluating glycosyl complexes on living cell surfaces.  Such information is invaluable for clinical biomarker research.

Read the paper for free until 30th August to learn more…

Synthesis and cell-surface binding of lectin-gold nanoparticle conjugates

Jine Wang, Dianjun Liu and Zhenxin Wang
Anal. Methods
DOI: 10.1039/C1AY05151B

You might also find this critical review interesting

Technologies and strategies for glycoproteomics and glycomics and their application to clinical biomarker research

Fateme Tousi, William S. Hancock and Marina Hincapie
Anal. Methods, 2011, 3, 20-32
DOI: 10.1039/C0AY00413H

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)

Chitosan/MWCNTs nanocomposite for fast isolation of hemoglobin from human whole blood

The nanocomposite preparation protocol provides a useful strategy to obtain nano-particles for separation sciences with improved adsorption performance

A team from China has developed a solid-phase extraction procedure that can be used to isolate hemoglobin from complex sample matrices in work which will be of interest to those working in protein separation and proteomics.  The chitosan/multi-wall carbon nanotube nanocomposites are prepared via surface deposition-cross linking and compared to conventional chitosan adsorbents, the described nanocomposite has a very short adsorption equilibrium time and a high adsorption capacity.

Read the paper for free until 28th July.

Chitosan/carbon nanotube composites for the isolation of hemoglobin in the presence of abundant proteins
Xuwei Chen, Wenjing Wang, Zhining Song and Jianhua Wang
Anal. Methods
DOI: 10.1039/C1AY05130J

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)

Analytical Methods Volume 3, Issue 6 now online.

 Anal. Methods, 2011, 3(6), 1215-1434

Anal. Methods, 2011, 3(6), 1215-1434

Yan Jin and colleagues propose an electrochemical method for the selection of natural G-quadruplex-binding ligands in their communication featured on the front cover.

Electrochemical selection of G-quadruplex-binding ligands based on structure-switching of telomeric DNA
Xiao-Qin Liu, Yan Jin, Yuexia Wang and Yunxia Qiao
Anal. Methods, 2011, 3, 1270-1273
DOI: 10.1039/C1AY05046J

This communication will be free until the 21st July.

HOT papers in this issue include:

A novel method for the determination of individual lanthanides using an inexpensive conductometric technique
Komal Matharu, Susheel K. Mittal and S. K. Ashok Kumar
Anal. Methods, 2011, 3, 1290-1295
DOI: 10.1039/C0AY00747A

A Phos-tag-based fluorescence resonance energy transfer system for the analysis of the kinase reaction of a substrate peptide
Masao Somura, Kei Takiyama, Emiko Kinoshita-Kikuta, Eiji Kinoshita and Tohru Koike
Anal. Methods, 2011, 3, 1303-1309
DOI: 10.1039/C1AY05016H

Why not take a look at the articles today and blog your comments below.

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)