Analytical Methods Blog

Take a look below at the new HOT Articles just published in Analytical Methods. All these papers are free for you to read for the next three weeks.

A novel gold nanorod-based spectrographic method for evaluating the curcumin inhibitory action on HepG2 cells
Yanjuan Tang, Guimin Sun, Jiye Cai and Peihui Yang  
Anal. Methods, 2013, Advance Article
DOI: 10.1039/C3AY40249E

Rapid determination of preliminary thalassaemia screening indicators based on near-infrared spectroscopy with wavelength selection stability
Tao Pan, Jinming Liu, Jiemei Chen, Guopeng Zhang and Yan Zhao 
Anal. Methods, 2013,5, 4355-4362
DOI: 10.1039/C3AY40732B

A novel test strip for toxicity assessment using luminescent bacteria in hydrogel
Xiaodong Nie, Jinling Zhang, Xiran Jiang, Sixiu Liu, Haisong Cui, Pengyuan Yang and Guodong Sui  
Anal. Methods, 2013,5, 4386-4390
DOI: 10.1039/C3AY40766G

 Classification of Raman spectra of single cells with autofluorescence suppression by wavelength modulated excitation
Sebastian Dochow, Norbert Bergner, Christoph Krafft, Joachim Clement, Michael Mazilu, Bavishna B. Praveen, Praveen C. Ashok, Rob Marchington, Kishan Dholakia and Jürgen Popp  
Anal. Methods, 2013, Advance Article
DOI: 10.1039/C3AY40193F

Development and optimization of an ELISA based method to detect Listeria monocytogenes and Escherichia coli O157 in fresh vegetables
Marina Cavaiuolo, Spiros Paramithiotis, Eleftherios H. Drosinos and Antonio Ferrante  
Anal. Methods, 2013, Advance Article
DOI: 10.1039/C3AY40893K

Preliminary studies into the effect of environmental degradation on the characterisation of automotive clear coats by attenuated total reflectance infrared spectroscopy
Georgina Sauzier, Mark Maric, Wilhelm van Bronswijk and Simon W. Lewis 
Anal. Methods, 2013, Advance Article
DOI: 10.1039/C3AY40458G

An emergent optimal precision in chemical measurement at low concentrations
Michael Thompson  
Anal. Methods, 2013,5, 4518-4519
DOI: 10.1039/C3AY40557E

Effect of hydrogen peroxide oxidation systems on human urinary steroid profiles
Unnikrishnan Kuzhiumparambila and   Shanlin Fu*a  
Anal. Methods, 2013,5, 4402-4408
DOI: 10.1039/C3AY40181B

Dynamic solid phase microextraction analysis for airborne methamphetamine: quantitation using isotopically substituted methamphetamine
Elizabeth J. McKenzie, Gordon M. Miskelly and Paul A. G. Butler 
Anal. Methods, 2013,5, 4391-4396
DOI: 10.1039/C3AY40536B

Take a look at our latest HOT articles just published in Analytical Methods! They will be free to read until August 3^rd. Click on the links below:

Applications of voltammetric ion selective electrodes to complex matrices
Alexander R. Harris, Jie Zhang, Robert W. Cattrall and   Alan M. Bond 
Anal. Methods, 2013, Advance Article
DOI: 10.1039/C3AY40769A

Internal standardization in axially viewed inductively coupled plasma optical emission spectrometry (ICP OES) combined with pneumatic nebulization and aerosol desolvation
Guilherme Luiz Scheffler and   Dirce Pozebon
Anal. Methods, 2013, Advance Article
DOI: 10.1039/C3AY40723C

Nanomaterial-based electrochemical detection of explosives: a review of recent developments
Aoife M. O’Mahony and   Joseph Wang
Anal. Methods, 2013, Advance Article
DOI: 10.1039/C3AY40636A

Mass spectral analysis of blood samples

Analysing blood samples for the presence of legal and illegal drugs can present a challenge to forensic scientists; blood is a complex matrix which requires cleaning up before analysis, and the standard tests tend to be specific to a single drug or drug class.

Lambert Sørensen and Jørgen Hasselstrøm from the Department of Forensic Medicine at Aarhus University, Denmark, have developed a rapid method for quantification of around 50 drugs and metabolites in whole blood samples. The process uses ultra-high-performance liquid chromatography tandem mass spectrometry (UPLC-ESI-MS/MS) and shows low limits of detection even with post-mortem blood samples, which are more difficult to analyse due to varying degrees of putrefaction.

The simple sample preparation procedure involves deproteinisation by methanol/acetonitrile and ultrafiltration of the extract, and the researchers used a 96-well format to obtain high sample throughput.

To know more, access the link below. This paper will be free to read for the next 10 days.

A high-throughput multi-class liquid chromatography tandem mass spectrometry method for quantitative determination of licit and illicit drugs in whole blood
Lambert K. Sørensen* and   Jørgen B. Hasselstrøm
Anal. Methods, 2013,5, 3185-3193
DOI: 10.1039/C3AY40443A

Take a look at our new selected HOT articles just published in Analytical Methods. They are all free for you to read until June 28th. Have a read now!

Supramolecular dispersive liquid–liquid microextraction based solidification of floating organic drops for speciation and spectrophotometric determination of chromium in real samples
Malihe Dehghani Mohammad Abadi, Mahmoud Chamsaz, Mohammad Hossein Arbab-Zavar and Farzaneh Shemirani  
Anal. Methods, 2013, Advance Article
DOI: 10.1039/C3AY00036B 
 
A ratiometric fluorescent sensor for Ag⁺ based on 8-hydroxyquinoline platform in aqueous media
Huajie Xu, Zhaodi Liu, Liangquan Sheng, Deqian Huang, Hong Zhang, Chongfu Song, Mingming Chena and  Wuyang Hua  
Anal. Methods, 2013, Advance Article
DOI: 10.1039/C3AY40277K 
 
Application of portable spectrometer for ultra trace metal analysis after ionic liquid based microextraction
Xiaodong Wen, Qingwen Deng, Jiwei Wang and Xia Zhao  
Anal. Methods, 2013, Advance Article
DOI: 10.1039/C3AY40229K 
 
Highly sensitive determination of Orange II based on the dual amplified electrochemical signal of graphene and mesoporous TiO₂
Tian Gan, Junyong Sun, Zuomin Lin and Yuling Li  
Anal. Methods, 2013, Advance Article
DOI: 10.1039/C3AY40250A 
 
Elimination of interferences caused by simultaneous use of deuterated and carbon-13 standards in GC-MS analysis of polycyclic aromatic hydrocarbons (PAHs) in extracts from passive sampling devices
Matyas Ripszam, Roman Grabic and Peter Haglund  
Anal. Methods, 2013, Advance Article
DOI: 10.1039/C3AY40419F

Take a look at our selected HOT articles free to read until June 3rd.

A new DNA detection methodology based on Rayleigh scattering, the optimised analysis of cellulose depolymerisation and the evaluation of a standard method to measure diesel particulate matter (DPM) exposures in underground mines are among the studies presented in these papers.

To access the full articles, just click on the links below:

Analysis of cellulose using high performance liquid chromatography with polar IL as an eluent.

A resonance Rayleigh scattering detection of DNA hybridization based on interaction between DNA and surfactants
Ying Ma, Changqun Cai, Lin Luo, Jiaqi Xie and   Xiaoming Chen  
Anal. Methods, 2013, Advance Article
DOI: 10.1039/C3AY40291F

Dissolution determination of five components in Huoxiang Zhengqi tablets using partitioned dispersive liquid-liquid microextraction combined with HPLC-UV
Huaizhong Guo, Xiaomin Pang, Weiquan Zhang, Wenyue Jiang and   Xiaocong Pang  
Anal. Methods, 2013, Advance Article
DOI: 10.1039/C3AY40153G

A person-wearable instrument to determine DPM exposures in underground metal/nonmetal mines

Direct HPILC analysis of cellulose depolymerisation in ionic liquids
Kosuke Kuroda, Yukinobu Fukay and   Hiroyuki Ohno
Anal. Methods, 2013, Advance Article
DOI: 10.1039/C3AY40182K

Real-time diesel particulate monitor for underground mines
James Noll, Samuel Janisko and   Steven E. Mischler  
Anal. Methods, 2013, Advance Article
DOI: 10.1039/C3AY40083B

Lipid bilayer structure of the liposome

The small size and lipid bilayer structure of liposomes make them an excellent carrier for use in drug delivery and gene therapy. Determining the chemical and physical properties of a liposome is key to evaluating its potential for different applications.

A range of techniques have been used to measure factors such as size, surface charge and encapsulation efficiency of these spherical structures. In this minireview, Xiaomei Yan and colleagues at Xiamen University, China, explore recent advances in techniques for single-liposome characterization. They evaluate the latest adaptations of traditional microscopy techniques and investigate the advantages and limitations of using flow cytometry for characterisation. Recently developed commercial techniques such as scanning ion occlusion sensing (SIOS) and nanoparticle tracking analysis (NTA) also offer more advanced methods of single-liposome analysis.

To access the full article, please click on the link below. This paper will be free to read until May 14th.

Analytical techniques for single-liposome characterization
Chaoxiang Chen, Shaobin Zhu, Tianxun Huang, Shuo Wanga and   Xiaomei Yan  
Anal. Methods, 2013,5, 2150-2157
DOI: 10.1039/C3AY40219C