Drug discovery, development, and manufacturing widely make use of high performance liquid chromatography (HPLC) to separate compound mixtures for identification, quantification, and purification of individual components. Hence, the quest for the “next generation” of HPLC instruments is in high demand for improved analysis. Monica Yang and colleagues from Merck and Eksigent corporations have tested the performance of Eksigent Express LC Ultra micro high pressure liquid chromatography for real-world pharmaceutical application. By combining the capability of microflow HPLC, and the function to separate under high pressures, the new instrument enables fast separation efficiency, cost reduction and high system reproducibility.
Find out more about this recent advancement by accessing the link below:
Evaluation of micro ultra high pressure liquid chromatography for pharmaceutical analysis
Monica (Mei) Yang , Xiaoyi Gong , Wes Schafer , Don Arnold and Christopher J. Welch
Anal. Methods, 2013, Advance Article
DOI: 10.1039/C3AY26435A