HOT article: Improving the stationary phase for HPLC

Liang et al., Anal. Methods, Advance Article

Silica-based stationary phases are very commonly used for high performance liquid chromatography but in most cases cannot be used above pH of 8. There have been a number of approaches used, mainly including post-synthesis grafting and direct synthesis, to improve the high pH stability of silica-based stationary phases. In this paper, Xinmiao Liang and colleagues from Dalian Institute of Chemical Physics have used porous spherical silicon oxynitride (sph-SiON) material as a stationary phase for HPLC. Read more about their work below.

Silicon oxynitride microspheres as stationary phase for high performance liquid chromatography
Huihui Wan, Xingya Xue, Yuguang Du and Xinmiao Liang
Anal. Methods, 2012, Advance Article
DOI: 10.1039/C2AY25783A

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