Causin, Anal. Methods, 2010, 2, 792-804
In this month’s Top Ten: prototyping chip devices, polymers on crime scenes, trace metals in water, nanomaterials in biomedical applications and more.
See what made the Top Ten and access all the articles in full
Submission are now welcome for an upcoming themed issue on Analysis in Sport. We’re very excited about the London 2012 Olympics, which take place later this year, and are looking to highlight the importance of analytical science in sporting success.
We’d like to cover the whole spectrum of sport analysis: anti-doping tests, drug monitoring, athlete health, issues with equipment and animals, safety concerns and regulations.
The deadline for submissions is 18 May 2012. The first articles will go online as the Olympics start, with the full issue to be published once the games have been completed.
You can submit your paper online, or contact us if you have any queries. Of course, all submissions will undergo peer-review in the usual manner.
We look forward to publishing an exciting collection of papers!
The latest issue of Analytical Methods includes some new papers from our continuing web theme on Future Electroanalytical Developments. This collection of articles highlights important developments and novel applications in this exciting area of research, and features papers from Analyst, Analytical Methods and other RSC journals.
Monitoring of bovine serum albumin using ultrasensitive electrochemiluminescence biosensors based on multilayer CdTe quantum dots modified indium tin oxide electrodes
Meng Zhang, Mei Yan, Jinghua Yu, Shenguang Ge, Fuwei Wan and Lei Ge
Anal. Methods, 2012, 4, 460-466
DOI: 10.1039/C1AY05481C
A novel electrochemical sensor based on boronic acid-functionalized multi-walled carbon nanotubes for astragaloside IV determination using ARS as the current indicator
Li Gu, Ying Liang, Tianshu Zhou, Xiaoshan Tang and Guoyue Shi
Anal. Methods, 2012, 4, 492-495
DOI: 10.1039/C1AY05553D
If you work in the area of electrochemical sensors and detection, submit your next paper and it could be selected for inclusion in this web theme.
Featured in the latest issue: a Critical Review on magnetic resonance techniques and a number of HOT articles, which will be free to access until the end of February. Don’t forget to take a look at the issue in full via the journal homepage.
Critical Review: Low field magnetic resonance techniques in the development of nanomaterials for biomedical applications
Carla J. Meledandri and Dermot F. Brougham
Anal. Methods, 2012, 4, 331-341
DOI: 10.1039/C2AY05420E
Communication: Engineering a unimolecular multifunctional DNA probe for analysis of Hg2+ and Ag+
Xiaoxiao He, Zhihe Qing, Kemin Wang, Zhen Zou, Hui Shi and Jin Huang
Anal. Methods, 2012, 4, 345-347
DOI: 10.1039/C2AY05823E
Communication: Simultaneous determination of two important dopamine metabolites at physiological pH by voltammetry
S. Brillians Revin and S. Abraham John
Anal. Methods, 2012, 4, 348-352
DOI: 10.1039/C2AY05664J
Communication: A new labelling reagent for glycans analysis by capillary electrophoresis-mass spectrometry
Cai Tie and Xin-Xiang Zhang
Anal. Methods, 2012, 4, 357-359
DOI: 10.1039/C2AY05741G
Communication: A graphene oxide–rhodamine 6G nanocomposite as turn-on fluorescence probe for selective detection of DNA
Xue Wang, Shuhua Zhong, Yu He and Gongwu Song
Anal. Methods, 2012, 4, 360-362
DOI: 10.1039/C2AY05827H
Arsenic species and selected metals in human urine: validation of HPLC/ICPMS and ICPMS procedures for a long-term population-based epidemiological study
Jürgen Scheer, Silvia Findenig, Walter Goessler, Kevin A. Francesconi, Barbara Howard, Jason G. Umans, Jonathan Pollak, Maria Tellez-Plaza, Ellen K. Silbergeld, Eliseo Guallar and Ana Navas-Acien
Anal. Methods, 2012, 4, 406-413
DOI: 10.1039/C2AY05638K
Monitoring intracellular nitric oxide production using microchip electrophoresis and laser-induced fluorescence detection
Emilie R. Mainz, Dulan B. Gunasekara, Giuseppe Caruso, Derek T. Jensen, Matthew K. Hulvey, Jose Alberto Fracassi da Silva, Eve C. Metto, Anne H. Culbertson, Christopher T. Culbertson and Susan M. Lunte
Anal. Methods, 2012, 4, 414-420
DOI: 10.1039/C2AY05542B
Multivariate calibration of near-infrared spectra by using influential variables
Xueguang Shao, Min Zhang and Wensheng Cai
Anal. Methods, 2012, 4, 467-473
DOI: 10.1039/C2AY05609G
Mass spectrometric imaging as a high-spatial resolution tool for functional genomics: Tissue-specific gene expression of TT7 inferred from heterogeneous distribution of metabolites in Arabidopsis flowers
Andrew R. Korte, Zhihong Song, Basil J. Nikolau and Young Jin Lee
Anal. Methods, 2012, 4, 474-481
DOI: 10.1039/C2AY05618F
A simple and sensitive colorimetric method for detection of mercury ions based on anti-aggregation of gold nanoparticles
Tingting Lou, Ling Chen, Chunrong Zhang, Qi Kang, Huiyan You, Dazhong Shen and Lingxin Chen
Anal. Methods, 2012, 4, 488-491
DOI: 10.1039/C2AY05764F
Front cover: Cizdziel et al., Anal. Methods, 2012, 4, 564-569
Take a look at the latest issue of Analytical Methods, now available online.
The stunning front cover highlights work from James Cizdziel of the University of Mississippi, and colleagues.
They evaluate the use of multiple botanical reference materials as LA-ICP-MS standards for quantifying the spatial distribution of elements in desert leaves.
Determination of elements in situ in green leaves by laser ablation ICP-MS using pressed reference materials for calibration
James Cizdziel, Kaixuan Bu and Piotr Nowinski
Anal. Methods, 2012, 4, 564-569
DOI: 10.1039/C1AY05577A
The inside front cover features a sensitive and selective analytical method utilising LC-ESI-MS/MS for the semi-quantitative determination of biogenic amines and amino acids in porcine decomposition fluid.
This paper is from Simon Lewis and colleagues from Curtin University, Perth, Australia, and was highlighted as a HOT article when it first appeared online.
Inside front cover: Swann et al., Anal. Methods, 2012, 4, 363-370
Determination of amino acids and amines in mammalian decomposition fluid by direct injection liquid chromatography-electrospray ionisation-tandem mass spectrometry
Lisa M. Swann, Francesco Busetti and Simon W. Lewis
Anal. Methods, 2012, 4, 363-370
DOI: 10.1039/C1AY05447C
Both articles will be free to access for 6 weeks.
A method to diagnose urinary lithiasis at an early stage has been devised by Wei Hang and colleagues in Xiamen, China. The method can also distinguish between the different types of stone, which is important when considering treatment options.
Currently, distinguishing between types can only be done after the stones have been removed from a patient, making it difficult to prescribe a treatment.
Urinary lithiasis, stones in the lower urinary tract, has become more common, with about 100,000 new cases each year. It causes substantial pain and leads to renal failure. The stones are caused by a build up of organic materials and inorganic crystals.
The team’s diagnostic method uses elemental analysis on blood serum samples to detect the levels of barium, gallium, antimony and sodium; variations from the norm are linked to the appearance of stones. The test subjects could then be subdivided into calcareous and non-calcareous stone patients by metallomic profiling, and the team found that selenium levels play a major role in this classification.
Gao et al., Anal. Methods, 2012
Compared with urine samples, blood serum samples show smaller variability under normal physiological conditions so are a better choice for elemental screening, say the researchers.
Early diagnosis of urinary lithiasis via elementary profile of serum samples
Yao Gao, Ning Yang, Xiaomei Yan, Wei Hang, Jinchun Xing, Jiaxin Zheng, Eryi Zhu and Benli Huang
Anal. Methods, 2012, Advance Article
DOI: 10.1039/C2AY05705K
You may also be interested in:
Direct infusion mass spectrometry or liquid chromatography mass spectrometry for human metabonomics? A serum metabonomic study of kidney cancer
Lin Lin, Quan Yu, Xiaomei Yan, Wei Hang, Jiaxin Zheng, Jinchun Xing and Benli Huang
Analyst, 2010, 135, 2970-2978
DOI: 10.1039/C0AN00265H
Critical Review: Combination of PAGE and LA-ICP-MS as an analytical workflow in metallomics: state of the art, new quantification strategies, advantages and limitations
Alessandra Sussulini and Johanna Sabine Becker
Metallomics, 2011, 3, 1271-1279
DOI: 10.1039/C1MT00116G
Anderson et al., Anal. Methods, 2012, 4, 101-105
Dana Spence and colleagues at Michigan State University have developed a way to study the P2X1 receptor on platelets, providing new possibilities for the research of these important cells.
The primary function of platelets in the bloodstream involves maintaining hemostasis and preventing blood loss through the clotting process.
Platelets are found in the bloodstream and function to maintain hemostasis and prevent blood loss via clotting. Adenine receptors on the surface of the platelet are important in this process, most notably the ADP-sensitive receptors P2Y1/P2Y12, and the ATP-sensitive P2X1 receptor.
Roles for P2Y-type receptors in platelet activation are well established, but the role of the P2X1 receptor is less clear as it has proven difficult to study. P2X1 is rapidly desensitised during in vitro experiments, particularly when the platelets have been separated from plasma and washed.
Professor Dana Spence, Michigan State University, USA
Here, Professor Spence – who is on the Advisory Board of Analytical Methods‘ sister journal, Analyst – and his team use the reported P2X1 inhibitor NF449 to sensitise washed platelets, enabling them to be properly studied.
In a press release from MSU, Professor Spence says, “This receptor, P2X1, has long been viewed as not important in platelets; our studies show that is not necessarily true. The receptor is very active; you just need to be careful in working with it.”
He hopes that this now opens up investigation of the P2X1 receptor as a potential drug target for the treatment of conditions such as diabetes and hypertension.
Read the paper in full:
Measuring P2X1 receptor activity in washed platelets in the absence of exogenous apyrase
Kari B. Anderson , Welivitiya Karunarathne and Dana M. Spence
Anal. Methods, 2012, 4, 101-105
DOI: 10.1039/C1AY05530E
