We have collected together some of the latest exciting research published in the journal from researchers working in France, Italy and Spain.
Read the highlighted articles in this web themed issue, which has been guest edited by José Pingarrón (Complutense University of Madrid, Spain) and Serge Cosnier (Université Joseph Fourier, France).
Let us know your thoughts on these articles, or about the analytical sciences in France, Italy and Spain more generally, by posting a comment below.
Want to find out more?
The Applied Materials Chemistry Group from the RSC are hosting a one day workshop on Surface chemistry and the non-specific binding problem in biosensor technology.
Date: May 9th, 2011 (9:15 AM – 5:00 PM)
Location: Burlington House, Royal Society of Chemistry, Piccadilly, London, UK
For more information and how to register, visit the website.
Considering that this phenomenon will ultimately dictate whether a biosensor can be commercialized or not, it is clear that a dedicated symposium on this subject is both timely and warranted. The subject matter is relevant to the fields of drug discovery, clinical diagnostics and environmental analysis, including homeland security and defense sectors.
PROGRAM
8:45 – 9:15 Registration
9:15-10:00 Professor Lisa Hall University of Cambridge, “Interfacial communication: a key requisite for Biosensor function”
10:00 – 10:45 Dr Helge Schnerr, TTP LabTech Ltd, Melbourn “Biosensors and the non-specific adsorption dilemma – Is there a way out?”
10:45 – 11:00 Coffee break
11:00 – 11:45 Professor Jean-Francois Masson, University of Montreal, “Detection of biomolecules in crude serum using peptide monolayers and microhole arrays”
11:45 – 12:30 Dr Christophe Blaszykowski, University of Toronto, “Antibiofouling behaviour of self-assembled monolayer-based biosensing platforms characterized by an ultra-high frequency acoustic wave sensor”
12:30 – 1:30 Buffet lunch
1: 30 – 2:15 Dr Sub Reddy, University of Surrey, “Towards protein-specific polymers and hydrogels and their use in sensors”
2: 15 – 3: 00 Dr Neil Hopkins, Dstl, UK “Engineering biofouling resistant surfaces: Topography and functionality”
3:00 – 3:15 Coffee break
3:15 – 4:00 Professor Mike Thompson, University of Toronto, “Selectivity of biological receptors: Relevance to biosensor development”.
4:00 – 5:00 Discussion
Registration fee; 75 pounds for academic delegates; 100 pounds industry delegate. Fee includes a lunch and all proceedings.
Analyst 2011, 136(10): 1997-2184
Issue 10 of Analyst 2011 is now online.
Work by Alberto Escarpa and co-workers is highlighted on the front cover. They have used a lab on a chip device to quickly analyse levels of zearalenone, a contaminant, in infant foods with a detection limit below legislative requirements.
This paper was recently highlighted by Chemistry World in a news piece. The full article will be free to access until the end of May, so do take a look:
Integrated electrokinetic magnetic bead-based electrochemical immunoassay on microfluidic chips for reliable control of permitted levels of zearalenone in infant foods
Mirian Hervás, Miguel A. López and Alberto Escarpa
Analyst, 2011, 136, 2131-2138
DOI: 10.1039/C1AN15081B
The potential of microchip electrophoresis for the rapid and highly sensitive analysis of mRNA expression in cells by using a Cy5-labeled antisense riboprobe in the RNA protection assay has been shown by researchers from Japan.
Shouki Yatsushiro and colleagues from National Institute of Advanced Industrial Science and Technology (AIST), Takamatsu, show that results can be obtained in 120 seconds, using the same amount of riboprobe as used in the conventional method, with eight-times more sensitive detection of mRNA.
Read the article for free using the link below:
Ribonuclease protection assay on microchip electrophoresis
Yuka Yamaguchi, Shouki Yatsushiro, Shohei Yamamura, Hiroko Abe, Kaori Abe, Masahiro Watanabe, Kazuaki Kajimoto, Yasuo Shinohara, Yoshinobu Baba and Masatoshi Kataoka
Analyst, 2011, Advance Article
DOI: 10.1039/C0AN01044H
The most popular Analyst articles in March
Five of our most-read papers in March 2011 – access them FOR FREE:
Melamine sensing through riboflavin stabilized gold nanoparticles
Bappaditya Roy, Abhijit Saha and Arun K. Nandi, Analyst, 2011, 136, 67-70
DOI: 10.1039/C0AN00599A
An improved method for diagnosing colorectal cancer without using invasive techniques has been developed by scientists in China. A team led by Guohua Zhou at Nanjing University used a bead-based assay in conjunction with PCR to detect the RNA produced by cancer cells.
Read David Barden’s news piece in Chemistry World or access the full article for free using the link below. What impact do you think this methodology will have for diagnostics in the future? Leave your comments below.
Digital analysis of the expression levels of multiple colorectal cancer-related genes by multiplexed digital-PCR coupled with hydrogel bead-array
Zongtai Qi, Yinjiao Ma, Lili Deng, Haiping Wu, Guohua Zhou, Tomoharu Kajiyama and Hideki Kambara
Analyst, 2011, Advance Article
DOI: 10.1039/C0AN00976H
Colloquium Spectroscopicum Internationale XXXVII
Buzios, Rio de Janeiro, Brazil
August 28 – September 2, 2011
Since the first meeting in France in 1949, the CSI conference has been a forum where scientists involved in all aspects of spectroscopy and spectrometry meet to share experiences, discuss results and applications and present new ideas.
This year the meeting will be hosted in South America for the first time in its 60 years of history. Visit http://www.csixxxvii.org/ for more details.
Abstract submission deadline April 30th 2011
The Analytical Research Forum (ARF11) is a major event for researchers in analytical science, and will be held in Manchester, 25 – 27 July 2011.
Poster abstracts and early bird registration deadline: 27 May 2011
Aimed at early stage analytical science students, the invited lectures have been selected to reflect a broad range of research interests. And if you’ve ever wondered what analytical science can do for research in the life sciences, then the additional optional workshop is for you:
Analytical Science in the Manchester Interdisciplinary Biocentre (MIB)
Generously supported by the Analytical Chemistry Trust Fund (ACTF) of the Analytical Division, there are a number of discretionary travel bursaries on offer – apply by the 27 May deadline.
Find full details at www.rsc.org/ARF11
Analyst, 136(9): 1769-1996
Issue 9 is now online! (apologies for the poetry, it’s just the best way to say it…)
Highlighted on this issue’s cover is work by Tony Killard and colleagues on the development of a fluorescent method for detecting the onset of coagulation in human plasma on microstructured lateral flow platforms. They’ve found that the change in the distribution of the fluorescence within the sample over time was an excellent predictor of the onset of coagulation, which could be used to determine the clotting time.
Read the article for free by clicking below:
Development of a fluorescent method for detecting the onset of coagulation in human plasma on microstructured lateral flow platforms
Magdalena M. Dudek, Nigel J. Kent, Pan Gu, Z. Hugh Fan and Anthony J. Killard
Analyst, 2011, 136, 1816-1825
DOI: 10.1039/C0AN00907E
Also in this issue are a handful of Communications, describing urgent work on topics such as detection of dopamine using fast scan cyclic voltammetry and the preparation of gold nanoparticle-decorated microparticles for hydrogen peroxide detection – do take a look and let us know your thoughts.
The results preliminarily revealed that modifications of metabolism and associated pathways accounted for metabolic perturbation of the rats that was induced by indomethacin.
Read this HOT paper which combines the use of high-throughput mass spectrometry based metabolomics and ingenuity pathway analysis, a powerful chemomatric approach, to address drug side-effects. By using differentiated global metabolic profiling of urine to phenotype the side effects of indomethacin on specific tissue systems it will elucidate the harmful effects of indomethacin in the kidney and liver, a key obstacle to widening the clinical use of the drug.
The paper will be free to access to until 24th May.
Metabolomic analysis characterizes tissue specific indomethacin-induced metabolic perturbations of rats
Haitao Lv, Lian Liu, Gustavo Palacios and Xi Chen
Analyst, 2011, Advance Article
DOI: 10.1039/C1AN15126F
