Graham Cooks to deliver Pittcon 2012 plenary

Prof. Cooks is Henry B. Hass Distinguished Professor–Analytical Chemistry in the Department of Chemistry at Purdue University

We’re delighted that Analyst Editorial Board member, Professor Graham Cooks, will be the plenary speaker at Pittcon 2012.

His talk will be entitled “Ambient Ionization and Mini Mass Spectrometers: In situ MS for Everyone” and will take place at 4.30 p.m. on Sunday 11th March in the Chapin Theater.

Watch this space for more details on our attendance at Pittcon!

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Diagnosing tumours in the nasopharynx without surgery

"Bringing optical histopathology into the clinic would have a huge impact for surgeons, pathologists and patients," says Dr Bevin Lin

Detecting early-stage nasopharyngeal carcinomas via a non-invasive technique which could improve the survival rates of patients has been reported by scientists from Singapore.  Diagnosing nasopharyngeal carcinomas before they have become life-threatening is very difficult, with five-year survival rates only around 34 per cent.

A team led by Bevin Lin, from the National University of Singapore, has developed a technique that uses a bifurcated fibre optic probe to collect nasopharyngeal tissue data. By combining ultraviolet auto fluorescence excitation-emission matrix (EEM) spectroscopy and parallel factor analysis calculations, they can then diagnose early-stage carcinomas.

To find out more, including comments from Dr Lin, read Jennifer Newton‘s article in Chemistry World, and access the paper for free using the link below.

Diagnosis of early stage nasopharyngeal carcinoma using ultraviolet autofluorescence excitation–emission matrix spectroscopy and parallel factor analysis
Bevin Lin, Mads Sylvest Bergholt, David P. Lau and Zhiwei Huang
Analyst, 2011
DOI: 10.1039/c1an15525c

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Have you seen the Issue 16 covers?

Analyst, 2011, 136(16): 3205-3392

Just in case you missed them, click below to see the great cover articles from Issue 16.

The front cover features work from Taesung Kim, Sung Kuk Lee and co-workers, describing their microfluidic device that identifies the preferential chemotactic responses of bacterial cells toward carbon sources.

Microfluidic device for analyzing preferential chemotaxis and chemoreceptor sensitivity of bacterial cells toward carbon sources
Minseok Kim, Su Hyun Kim, Sung Kuk Lee and Taesung Kim
Analyst, 2011, 136, 3238-3243
DOI: 10.1039/C1AN15308K

Research by Hua Cui and co-workers on the development of an ultrasensitive ECL aptasensor for protein detection based on a functionalized gold nanoprobe is highlighted on the inside front cover.

A novel electrochemiluminescence aptasensor for protein based on a sensitive N-(aminobutyl)-N-ethylisoluminol-functionalized gold nanoprobe
Ying Chai, Dayong Tian, Jie Gu and Hua Cui
Analyst, 2011, 136, 3244-3251
DOI: 10.1039/C1AN15298J

Both these articles are free for the next 4 weeks, so do take a look and pass on to colleagues.

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Thermochemiluminescence patterns act as fingerprints to accurately classify proteins

Albumin solutions were added directly onto each sensing element. When heated, the albumins are thermally oxidised, generating distinct thermochemiluminescence patterns.

We’ve just published the latest paper from Analyst‘s Associate Editor for Asia, Xinrong Zhang, and colleagues from Tsinghua Universtiy, China.  It details an innovative nanomaterial array which uses chacteristic thermochemiluminescence signals to recognise protein subtypes and denatured shapes.

Read the paper for free until 8th September.

A thermochemiluminescence array for recognition of protein subtypes and their denatured shapes
Hao Kong, He Wang, Sichun Zhang and Xinrong Zhang
Analyst
DOI: 10.1039/C1AN15382J

Recap on Xinrong Zhang’s previous paper on an aerosol chemiluminescence-based sensor which functions as a mammalian tongue….

Recognition of organic compounds in aqueous solutions by chemiluminescence on an array of catalytic nanoparticles

Hao Kong, Sichun Zhang, Na Na, Da Liu and Xinrong Zhang
Analyst, 2009, 134, 2441-2446
DOI: 10.1039/B917538E

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Grand challenges: Surface enhanced optical spectroscopies for bioanalysis

Surface enhancement can provide improved detection sensitivity in a range of optical spectroscopies.

Read this comprehensive review on surface enhanced optical spectroscopies and their application to bioanalysis by Analyst Editorial Board member Duncan Graham and his colleague Iain Larmour.  They consider the “grand challenges” that need to be overcome before widespread clinical use of surface enhanced techniques can be achieved.

The review will be free until the 6th September.

Surface enhanced optical spectroscopies for bioanalysis

Iain A. Larmour and Duncan Graham
Analyst
DOI: 10.1039/C1AN15452D

This paper is part of an ongoing collection of articles looking at Grand Challenges in analytical science.  In celebration of the International Year of Chemistry, leading scientists (including our own Board members) have put together papers outlining the current challenges faced in analytical science, and how these might be tackled, some of which were published in issue 15.

Below are a selection of recent Analyst papers mentioned in the review:

Evaluation of tip-enhanced Raman spectroscopy for characterizing different virus strains
Peter Hermann, Antje Hermelink, Veronika Lausch, Gudrun Holland, Lars Möller, Norbert Bannert and Dieter Naumann
Analyst, 2011, 136, 1148-1152
DOI: 10.1039/C0AN00531B

Surface enhanced Raman evidence for Ag+ complexes of adenine, deoxyadenosine and 5′-dAMP formed in silver colloids
Evanthia Papadopoulou and Steven E. J. Bell
Analyst, 2010, 135, 3034-3037
DOI: 10.1039/C0AN00612B

Competitive surface-enhanced Raman scattering assay for the 1,25-dihydroxy metabolite of vitamin D3
Eric J. Dufek, Brian Ehlert, Michael C. Granger, Tanya M. Sandrock, Samuel L. Legge, Mark G. Herrmann, A. Wayne Meikle and Marc D. Porter
Analyst, 2010, 135, 2811-2817
DOI: 10.1039/C0AN00354A

Short-wave infrared excited SERS
Kirstin A. Lynn, Graeme McNay, David A. Eustace, Neil C. Shand and W. Ewen Smith
Analyst, 2010, 135, 1904-1905
DOI: 10.1039/C0AN00096E

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International Symposium on Enabling Technologies – Atlantic Conference

6th International Symposium on Enabling Technologies (ETP Boston)
October 7, 2011, Boston MA, U.S.

 

The 6th International Symposium on Enabling Technologies – Atlantic Conference will be held in Boston later this year on October 7th. JAAS Editorial Board member, Dr Scott Tanner from University of Toronto and Metallomics author Jane Thomas-Oates, University of York are amongst the impressive line-up of speakers. Read a selection of some of the speakers latest research below.

For further details, visit the conference website. Abstract submission and registration now open!

Don’t forget to pick up a complimentary copy of our analytical journals, if you are planning to attend!

Development of analytical methods for multiplex bio-assay with inductively coupled plasma mass spectrometry
Olga I. Ornatsky, Robert Kinach, Dmitry R. Bandura, Xudong Lou, Scott D. Tanner, Vladimir I. Baranov, Mark Nitz and Mitchell A. Winnik
J. Anal. At. Spectrom., 2008, 23, 463-469, DOI: 10.1039/B710510J

Denaturing and non-denaturing microsolution isoelectric focussing to mine the metalloproteome
Barbara Pioselli, Caroline Munro, Andrea Raab, Christian L. Deitrich, Kriangsak Songsrirote, Jörg Feldmann and Jane Thomas-Oates
Metallomics, 2009, 1, 501-510, DOI: 10.1039/B903607E

Characterizing the connectivity of poly-ubiquitin chains by selected reaction monitoring mass spectrometry
Hamid Mirzaei, Richard S. Rogers, Barbara Grimes, Jimmy Eng, Alan Aderem and Ruedi Aebersold
Mol. BioSyst., 2010, 6, 2004-2014, DOI: 10.1039/C005242F

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Ricin biosensor outperforms current methods to detect food contamination

Ricin, a toxin derived from the castor bean plany may be easily amendable as a deliberate food biocontaminate

This study describes the characterisation and selection of an aptamer against the toxin, ricin B.  The aptamer functioned well in liquid food matrices and was tested against a commercially available ELISA kit.

Read the paper for free until 30th August to learn more…

A single DNA aptamer functions as a biosensor for ricin
Elise A. Lamont, Lili He, Keith Warriner, Theodore P. Labuza and Srinand Sreevatsan
Analyst
DOI: 10.1039/C1AN15352H

You might also be interested in these papers:

Aptamer-based surface-enhanced Raman scattering detection of ricin in liquid foods
Lili He, Elise Lamont, Belamaranahally Veeregowda, Srinand Sreevatsan, Christy L. Haynes, Francisco Diez-Gonzalez and Theodore P. Labuza
Chem. Sci., 2011, 2, 1579-1582
DOI: 10.1039/C1SC00201E

Simultaneous quantification of five bacterial and plant toxins from complex matrices using a multiplexed fluorescent magnetic suspension assay
Diana Pauly, Sebastian Kirchner, Britta Stoermann, Tanja Schreiber, Stefan Kaulfuss, Rüdiger Schade, Reto Zbinden, Marc-André Avondet, Martin B. Dorner and Brigitte G. Dorner
Analyst, 2009, 134, 2028-2039
DOI: 10.1039/B911525K

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Introducing a new Analyst Associate Editor for Asia!

Takehiko KitamoriWe are delighted to announce that Takehiko Kitamori from the University of Tokyo is the latest leading scientist to join the Analyst team, as Associate Editor for Asia.

He joins Xinrong Zhang (Associate Editor for Asia), Boris Mizaikoff (Associate Editor for Europe), Steve Soper (Associate Editor for the Americas) and Duncan Graham (Associate Editor for Reviews) as members of the Editorial Board who handle the peer-review of articles submitted to Analyst. Professor Kitamori welcomes submissions from Japan and South-East Asia.

Takehiko Kitamori is a full professor at the Department of Applied Chemistry, the Graduate School of Engineering, The University of Tokyo, and also he is Dean of both Faculty and Graduate School of Engineering. His research activity covers laser spectro-analytical chemistry, and micro and extended-nano chemistry. Read his latest review article in Analyst!

Critical Review: Extended nanospace chemical systems on a chip for new analytical technology
Kazuma Mawatari, Takehiko Tsukahara and Takehiko Kitamori
Analyst, 2011, 136, 3051-3059
DOI: 10.1039/C0AN00840K

Submit your next article to Analyst here!

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DESI and PADI ambient mass spectrometry analysis of anti-aging creams on model skin surfaces

DESI and PADI are useful when determining the siloxane contents of anti-aging creams.

Tara Salter and colleagues present a preliminary study for a non-invasive in vivo investigation of personal care products on fixed fibroblast cells. They carried our mass spectrometry analyses of 13 molecules commonly used in personal care products, including organosiloxanes, with both PADI and DESI to determine the different sensitivities of the techniques.

Read the paper for free until 16th August.

Analysis of personal care products on model skin surfaces using DESI and PADI ambient mass spectrometry
Tara L. Salter, Felicia M. Green, Nilofar Faruqui and Ian S. Gilmore
Analyst
DOI: 10.1039/C1AN15138J

On a similar note, why not check out the themed issue on ambient mass spectrometry that we published last year, in particular this paper from Graham Cooks and colleagues

Desorption electrospray ionization and other ambient ionization methods: current progress and preview

Demian R. Ifa, Chunping Wu, Zheng Ouyang and R. Graham Cooks
Analyst, 2010, 135, 669-681
DOI: 10.1039/B925257F

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Issue 15 online: tackling Grand Challenges

Analyst, 2011, 136(15): 3025-3204

Issue 15 is now available online, and we publish the first of an ongoing collection of articles looking at Grand Challenges in analytical science.  In celebration of the International Year of Chemistry, leading scientists (including our own Board members) have put together papers outlining the current challenges faced in analytical science, and how these might be tackled.

There are contributions in this issue from Lloyd Smith, and from Board members Pavel Matousek, Takehiko Kitamori and Facundo Fernandez.  Pavel’s minireview is also highlighted on the inside cover.

Minireview: Non-invasive analysis of turbid samples using deep Raman spectroscopy
Kevin Buckley and Pavel Matousek
Analyst, 2011, 136, 3039-3050
DOI: 10.1039/C0AN00723D

Critical Review: Extended nanospace chemical systems on a chip for new analytical technology
Kazuma Mawatari, Takehiko Tsukahara and Takehiko Kitamori
Analyst, 2011, 136, 3051-3059
DOI: 10.1039/C0AN00840K

Critical Review: To understand the whole, you must know the parts: unraveling the roles of protein–DNA interactions in genome regulation
Lloyd M. Smith, Michael R. Shortreed and Michael Olivier
Analyst, 2011, 136, 3060-3065
DOI: 10.1039/C1AN15037E

Poor quality drugs: grand challenges in high throughput detection, countrywide sampling, and forensics in developing countries
Facundo M. Fernandez, Dana Hostetler, Kristen Powell, Harparkash Kaur, Michael D. Green, Dallas C. Mildenhall and Paul N. Newton
Analyst, 2011, 136, 3073-3082
DOI: 10.1039/C0AN00627K

The stunning front cover of this issue highlights work by Jeremy Driskell from the lab of Ralph Tripp.  They report the development of a simple, rapid, and sensitive method for quantitative detection of influenza A virus using dynamic light scattering and gold nanoparticle labels.

One-step assay for detecting influenza virus using dynamic light scattering and gold nanoparticles
Jeremy D. Driskell, Cheryl A. Jones, S. Mark Tompkins and Ralph A. Tripp
Analyst, 2011, 136, 3083-3090
DOI: 10.1039/C1AN15303J

Don’t forget that Analyst cover articles are free for 6 weeks!

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