Analyst Issue 16 now online

In this issue of Analyst we have two lovely covers for you to admire. On the outside we have an image from Sangmin Jeon and colleagues from Pohang University of Science and Technology, Korea. In their paper they report a new way of detecting Salmonella bacteria, a common cause of food poisoning. This simple, rapid, and cost-effective method used magnetic (superparamagnetic) nanoparticles and TiO2 nanocrystals.

A facile and sensitive detection of pathogenic bacteria using magnetic nanoparticles and optical nanocrystal probes
Jinmyoung Joo, Changyong Yim, Donghoon Kwon, Jaejin Lee, Hwa Hui Shin, Hyung Joon Cha and Sangmin Jeon
Analyst, 2012, 137, 3609
DOI: 10.1039/C2AN35369E

From Zhong-Ping Yao at The Hong Kong Polytechnic University, China, comes the inside front cover. Together with a team from around China, they have been analyzing biological tissue at the molecular level. They have been able to directly ionize and analyze both plant and animal tissue by mass spectrometry under ambient conditions.

Direct ionization of biological tissue for mass spectrometric analysis
Bin Hu, Ying-Han Lai, Pui-Kin So, Huanwen Chen and Zhong-Ping Yao
Analyst, 2012, 137, 3613
DOI: 10.1039/C2AN16223G

These cover articles will be free to access for 6 weeks, so click through and have a read.

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Milking the benefits of multiple biomarkers

An illegal hormone used to promote milk production could soon be easy to detect in dairy herds, thanks to scientists in the Netherlands.

The hormone – recombinant bovine somatotropin (rbST) – is licensed in some countries, but, despite having no influence on human health, its use is banned in Europe due to concerns over the health and welfare of treated animals.

The direct detection of rbST is hindered by its similarity to the natural growth hormone produced by the animals, bST. Its blood serum concentration fluctuates significantly, and both bST and rbST are present at low concentrations. Measurements by methods such as liquid chromatography–mass spectrometry also suffer from a small detection window because of the short half-life of rbST in the blood.

The hormone recombinant bovine somatotropin is licensed in some countries, but its use is banned in Europe

The hormone recombinant bovine somatotropin is licensed in some countries, but its use is banned in EuropeT

To read the full article visit Chemistry World.

Multiplex flow cytometric immunoassay for serum biomarker profiling of recombinant bovine somatotropin

Nathalie Gabriëlle Esther Smits, Susann Ludwig, Grisha Van der Veer, Monique Bremer and Michel W F Nielen
Analyst
, 2012, Accepted Manuscript
DOI: 10.1039/C2AN35226E

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Better security with through-barrier detection using SORS

A team working in the UK have demonstrated that spatially offset Raman spectroscopy (SORS) using short wave infrared can detect chemicals through physical barriers such as containers, which is a step forward in detection and security.

The performance of SORS compared to conventional Raman (CR) spectroscopy to detect the sub-surface layer beneath a barrier is better because of its ability to suppress fluorescence and Raman scattering from the target container. However, there is still a problem with the fluorescence of the target chemical beneath, as this can mask the useful Raman signature that can be used to identify the contents.

Schematic diagram of experimental configuration used for 1064nm SORS measurements

Schematic diagram of experimental configuration used for 1064nm SORS measurements

To read the full article visit Chemistry World.

Short-wave infrared excited spatially offset Raman spectroscopy (SORS) for through-barrier detection

Rebecca J. Hopkins ,  Suzanne H. Pelfrey and Neil C. Shand
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35681C

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HOT articles in Analyst

Take a look at some of the HOT articles we’ve published recently in Analyst! These papers cover a wide variety of topics such as glucose detection, skin characterization, and bacterial spore analysis. They will be free to access for 2 weeks.

Gold nanoparticle–enzyme conjugates based FRET for highly sensitive determination of hydrogen peroxide, glucose and uric acid using tyramide reaction
Xiangyi Huang, Tao Lan, Bocheng Zhang and Jicun Ren
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35503E

Confocal Raman microspectroscopy for skin characterization: a comparative study between human skin and pig skin
Sana Tfaili, Cyril Gobinet, Gwendal Josse, Jean-François Angiboust, Michel Manfait and Olivier Piot
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN16292J

Ultrasensitive colorimetric detection of heparin based on self-assembly of gold nanoparticles on graphene oxide
Xiuli Fu, Lingxin Chen and Jinhua Li
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35552C

A homogeneous fluorescence sensing platform with water-soluble carbon nanoparticles for detection of microRNA and nuclease activity
Liyong Wang, Yongqiang Cheng, Hui Wang and Zhengping Li
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35396B

Analysis of the Raman spectra of Ca2+-dipicolinic acid alone and in the bacterial spore core in both aqueous and dehydrated environments
Lingbo Kong, Peter Setlow and Yong-qing Li
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35468C

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HOT articles in Issue 15

Fluorescent probe mimicking multiple=

HOT article: Misra et al., Analyst, 2012, 137, 3470-3478

This issue’s HOT articles feature the use of ligand–receptor interactions in 13C MRI, metal–organic framework MIL-101(Cr) microcrystals for rapid magnetic solid-phase extraction, odorant biosensors, SR-FTIR micro-imaging of latent fingerprints, a new fluorescent and colorimetric Cu2+ probe, and an efficient fluorescent probe mimicking multiple logic gates and a molecular-keypad lock.

All these papers will be free to access for 2 weeks.

Generating contrast in hyperpolarized 13C MRI using ligand–receptor interactions
Kayvan R. Keshari, John Kurhanewicz, Jeffrey M. Macdonald and David M. Wilson
Analyst, 2012, 137, 3427-3429
DOI: 10.1039/C2AN35406C

Facile magnetization of metal–organic framework MIL-101 for magnetic solid-phase extraction of polycyclic aromatic hydrocarbons in environmental water samples
Shu-Hui Huo and Xiu-Ping Yan
Analyst, 2012, 137, 3445-3451
DOI: 10.1039/C2AN35429B

Dissociated neuronal culture expressing ionotropic odorant receptors as a hybrid odorant biosensor—proof-of-concept study
Norio Tanada, Takeshi Sakurai, Hidefumi Mitsuno, Douglas J. Bakkum, Ryohei Kanzaki and Hirokazu Takahashi
Analyst, 2012, 137, 3452-3458
DOI: 10.1039/C2AN35058K

Detection of microscopic particles present as contaminants in latent fingerprints by means of synchrotron radiation-based Fourier transform infra-red micro-imaging
A. Banas, K. Banas, M. B. H. Breese, J. Loke, B. Heng Teo and S. K. Lim
Analyst, 2012, 137, 3459-3465
DOI: 10.1039/C2AN35355E

A new fluorescent and colorimetric probe for Cu2+ in live cells
Wei-Yong Liu, Hai-Ying Li, Bao-Xiang Zhao and Jun-Ying Miao
Analyst, 2012, 137, 3466-3469
DOI: 10.1039/C2AN35559K

Fluorescent probe mimicking multiple logic gates and a molecular keypad lock upon interaction with Hg2+ and bovine serum albumin
Arvind Misra, Priyanka Srivastava and Mohammad Shahid
Analyst, 2012, 137, 3470-3478
DOI: 10.1039/C2AN35561B

Follow Analyst on Twitter: @analystrscDon’t forget to take a look at the cover articles from Issue 15.

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Issue 15 now online

Analyst, 2012, Issue 15 front cover

Front cover: Nagatani et al., Analyst, 2012, 137, 3422-3426

In the latest issue of Analyst, the front cover features work from Eiichi Tamiya of Osaka University, Japan, and co-workers. They have detected the influenza virus using an amplified DNA detection lateral flow immunoassay (ADLFIA).

The sensitivity of their method is comparable to agarose gel electrophoresis but can be observed by the naked eye. The authors say this work is a step forward in their efforts towards a battery powered portable PCR chip, and a battery powered portable PCR chip with ADLFIA has the potential to give the portable system a diagnostic test.

Detection of influenza virus using a lateral flow immunoassay for amplified DNA by a microfluidic RT-PCR chip
Naoki Nagatani, Keiichiro Yamanaka, Hiromi Ushijima, Ritsuko Koketsu, Tadahiro Sasaki, Kazuyoshi Ikuta, Masato Saito, Toshiro Miyahara and Eiichi Tamiya
Analyst, 2012, 137, 3422-3426
DOI: 10.1039/C2AN16294F

On the inside front cover Christopher Szakal and colleagues at NIST, USA who present a novel method for correlating and classifying ion-specific time-of-flight secondary ion mass spectrometry (ToF-SIMS) images within a multispectral dataset by grouping images with similar pixel intensity distributions.

Analyst, 2012, Issue 15 inside front cover

Konicek et al., Analyst, 2012, 137, 3479-3487

They say that this algorithm should extend well into three-dimensional datasets, allowing for classification of chemical species as a function of depth into a sample.

Automated correlation and classification of secondary ion mass spectrometry images using a k-means cluster method
Andrew R. Konicek, Jonathan Lefman and Christopher Szakal
Analyst, 2012, 137, 3479-3487
DOI: 10.1039/C2AN16122B

Both these cover articles are free to access for 6 weeks.

Don’t forget to take a look at this issue’s HOT articles too, featuring the use of ligand–receptor interactions in 13C MRI, metal–organic framework MIL-101(Cr) microcrystals for rapid magnetic solid-phase extraction, odorant biosensors, SR-FTIR micro-imaging of latent fingerprints, a new fluorescent and colorimetric Cu2+ probe, and an efficient fluorescent probe mimicking multiple logic gates and a molecular-keypad lock.

Follow Analyst on Twitter: @analystrsc

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Analyst Impact Factor rises to 4.23!

Thomson Reuters has just released the 2011 Journal Citation Reports ® and we have great news for Analyst.

Our impact factor* (IF) has increased from last year to 4.23!

We would like to take this opportunity to thank all our authors, readers and referees who have contributed towards this success. And of course a giant thank you to the Editorial and Advisory Boards for all their hard work and dedication to the journal!

Find out how other RSC journals are ranked in the latest Impact Factor release.

Why not submit your latest piece of high impact work with us here.

*The IF provides an indication of the average number of citations per paper. Produced annually, IFs are calculated by dividing the number of citations in a year, by the number of citeable articles published in the preceding two years.

2011 Journal Citation Reports ®, (Thomson Reuters, 2012).

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GRC on Bioanalytical Sensors

I’m writing this from Boston Logan Airport, waiting to catch my flight after the 2012 GRC on Bioanalytical Sensors, which took place at Salve Regina University, Newport, Rhode Island, USA. The nature of GRC meetings mean that a lot of unpublished data are presented, so I can’t go into detail but I can tell you that it was an interesting and stimulating few days of excellent science. And the weather was an improvement on Cambridge too!

Chair of the meeting was our Associate Editor Professor Steve Soper, and one of the Vice-Chairs was Professor Sue Lunte, Associate Editor for our sister journal, Analytical Methods. In addition, a number of speakers have published with us, not just in Analyst but in a variety of journals – this really reflects the diverse nature of the programme, from surface chemistry to biology.

We’ve collected together some of these papers, which will be free to access until 13 July – do the use the opportunity to (re)discover the best in this area of research.

Take a look at the collection of papers here.

Including:

Sampling techniques for single-cell electrophoresis
Christine Cecala and Jonathan V. Sweedler
Analyst, 2012,137, 2922-2929
DOI: 10.1039/C2AN16211C

Bipolar electrode depletion: membraneless filtration of charged species using an electrogenerated electric field gradient
Eoin Sheridan, Kyle N. Knust and Richard M. Crooks
Analyst, 2011,136, 4134-4137
DOI: 10.1039/C1AN15510

Near-IR single fluorophore quenching system based on phthalocyanine (Pc) aggregation and its application for monitoring inhibitor/activator action on a therapeutic target: L1-EN
Irina V. Nesterova, Cecily A. Bennett, S. Sibel Erdem, Robert P. Hammer, Prescott L. Deininger and Steven A. Soper
Analyst, 2011,136, 1103-1105
DOI: 10.1039/C0AN00782J

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HOT articles in Analyst this June

It’s been a busy month with so many great papers, so here are some HOT articles from Analyst that you might have missed this June!

Why not take a look, they will be free to read for 2 weeks.

Short-wave infrared excited spatially offset Raman spectroscopy (SORS) for through-barrier detection
Rebecca J. Hopkins, Suzanne H. Pelfrey and Neil C. Shand
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35681C

A sensitive dual signal amplification method for western blotting based on antibody-functionalised graphene oxide and gold nanoparticles
Hongjun Lin, Jingrui Huo, Aihong Zhang, Yingfu Liu, Qingming Wang, Yun Cai, Wantao Ying, Weijie Qin, Yangjun Zhang and Xiaohong Qian
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35242G

A novel molecularly imprinted electrochemiluminescence sensor for isoniazid detection
Bowan Wu, Zhihua Wang, Zhonghua Xue, Xibin Zhou, Jie Du, Xiuhui Liu and Xiaoquan Lu
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35499C

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SPEC 2012: Optical Diagnosis themed issue

SPEC 2012-Shedding New Light on Disease, Thailand, November 11-16 2012.

The SPEC 2012 conference will be held later this year in Chiang Mai, Thailand, November 11-16. This year entitled “Shedding New Light on Disease” it is being chaired by Bayden Wood and Don McNaughton from Monash University, Australia.

As with previous SPEC conferences, Analyst is publishing a themed issue on Optical Diagnosis to feature papers from the conference and to highlight the latest advances in diagnosis and novel biomedical applications of infrared and Raman spectroscopy. You can read the editorial from the last themed issue on Optical Diagnosis here, and read the issue here.

This themed issue is scheduled to be published in the middle of 2013. The deadline for submission is 1 February 2013.

Take a look below at some of the great papers from the last themed issue.

Surface enhanced Raman evidence for Ag+ complexes of adenine, deoxyadenosine and 5′-dAMP formed in silver colloids
Evanthia Papadopoulou and Steven E. J. Bell
Analyst, 2010, 135, 3034-3037
DOI: 10.1039/C0AN00612B

Discrimination of zone-specific spectral signatures in normal human prostate using Raman spectroscopy
Imran I. Patel and Francis L. Martin
Analyst, 2010, 135, 3060-3069
DOI: 10.1039/C0AN00518E

Raman endoscopy for in vivo differentiation between benign and malignant ulcers in the stomach
Mads Sylvest Bergholt, Wei Zheng, Kan Lin, Khek Yu Ho, Ming Teh, Khay Guan Yeoh, Jimmy Bok Yan So and Zhiwei Huang
Analyst, 2010, 135, 3162-3168
DOI: 10.1039/C0AN00336K

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