Analyst Blog

HOT articles in Analyst

10 Aug 2012

Take a look below at some wonderful HOT articles we’ve recently published in Analyst. There are papers covering a large variety of fields, including electrochemiluminescence, metabolomics, diabetes research, Raman spectroscopy, and fluorescent probes. These papers will be free to read for two weeks.

Amplified electrochemiluminescence detection of nucleic acids by hairpin probe-based isothermal amplification
Xiaoming Zhou and Da Xing
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35367A

The surface-enhanced Raman spectra of aflatoxins: spectral analysis, density functional theory calculation, detection and differentiation
Xiaomeng Wu, Simin Gao, Jia-Sheng Wang, Hongyan Wang, Yao-Wen Huang and Yiping Zhao
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35378D

Eliminating the dication-induced intersample chemical-shift variations for NMR-based biofluid metabonomic analysis
Limiao Jiang, Jing Huang, Yulan Wang and Huiru Tang
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35392J

Exploratory urinary metabolic biomarkers and pathways using UPLC-Q-TOF-HDMS coupled with pattern recognition approach
Aihua Zhang, Hui Sun, Ying Han, Ye Yuan, Ping Wang, Gaochen Song, Xiaoxia Yuan, Miao Zhang, Ning Xie and Xijun Wang
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35780A

Use of imaging multivariate analysis to improve biochemical and anatomical discrimination in desorption electrospray ionisation mass spectrometry imaging
Wei Rao, David J. Scurr, James Burston, Morgan R. Alexander and David A. Barrett
Analyst, 2012, 137, 3946-3953
DOI: 10.1039/C2AN35430F

EOT or Kretschmann configuration? Comparative study of the plasmonic modes in gold nanohole arrays
Maxime Couture, Ludovic S. Live, Anuj Dhawan and Jean-Francois Masson
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35566C

The promise of electrochemical impedance spectroscopy as novel technology for the management of patients with diabetes mellitus
Teagan Leigh Adamson, Francis Ang Eusebio, Curtiss B. Cook and Jeffrey T. LaBelle
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35645G

Highly selective preconcentration of ultra-trace cadmium by yeast surface engineering
Ting Yang, Xiao-Xing Zhang, Ming-Li Chen and Jian-Hua Wang
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35755K

Raman microspectroscopy of live cells under autophagy-inducing conditions
Stanislav O. Konorov, Mario A. Jardon, James M. Piret, Michael W. Blades and Robin F. B. Turner
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35477B

Line shape distortion effects in infrared spectroscopy
Miloš Miljković, Benjamin Bird and Max Diem
Analyst, 2012, 137, 3954-3964
DOI: 10.1039/C2AN35582E

Cd(II)-triggered excimer–monomer conversion of a pyrene derivative: time dependent red-shift of monomer emission with cell staining application
Animesh Sahana, Arnab Banerjee, Sisir Lohar, Subarna Guha, Sudipta Das, Subhra Kanti Mukhopadhyay and Debasis Das
Analyst, 2012, 137, 3910-3913
DOI: 10.1039/C2AN35731C

Protein-templated gold nanoclusters as fluorescence probes for the detection of methotrexate
Zhanguang Chen, Sihua Qian, Xi Chen, Wenhua Gao and Yuejuan Lin
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35786K

Cavity-enhanced Raman spectroscopy with optical feedback cw diode lasers for gas phase analysis and spectroscopy
Robert Salter, Johnny Chu and Michael Hippler
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35722D

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HOT Article: A facile graphene oxide-based DNA polymerase assay

08 Aug 2012

By Rebecca Brodie, Deputy Editor.

A facile graphene oxide-based DNA polymerase assay

Wang et al., Analyst, 2012, 137, 3989

By Laura Ruvuna, Web Writer

In this HOT article, Analyst Advisory Board member Kemin Wang and co-workers from Hunan University, China, use graphene oxide acting as an optical switch in a DNA polymerase assay for the first time. DNA polymerase is important in molecular biological studies and functions as a key drug target. Typically, these assays use expensive and restrictive radioactive labels, which are unsuitable for a high throughput system. Unlike other fluorescence-based assays that require designed template sequences or expensive reagents, here the graphene oxide quenches the fluorescently labeled ssDNA. When the complementary strand binds, the DNA has less of an affinity for the graphene and the resulting fluorescence signal increases. To read more about this new and exciting assay, click the link below. It will be free to read for 2 weeks.

A facile graphene oxide-based DNA polymerase assay
Fengzhou Xu, Hui Shi, Xiaoxiao He, Kemin Wang, Xiaosheng Ye, Lv’an Yan and Shuyong Wei
Analyst, 2012, 137, 3989-3994
DOI: 10.1039/C2AN35585J

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HOT articles in Analyst for July

01 Aug 2012

By Aliya Anwar.

Check out some of the HOT articles published last month in Analyst that you may have missed. These papers will be free to access for 2 weeks!

¹³C cell wall enrichment and ionic liquid NMR analysis: progress towards a high-throughput detailed chemical analysis of the whole plant cell wall
Marcus Foston, Reichel Samuel and Arthur J. Ragauskas
Analyst, 2012, 137, 3904-3909
DOI: 10.1039/C2AN35344J

Transmission Raman measurement directly through packed corn kernels to improve sample representation and accuracy of compositional analysis
Kayeong Shin, Hoeil Chung and Chul-won Kwak
Analyst, 2012, 137, 3690-3696
DOI: 10.1039/C2AN35443H

A water soluble Al³⁺selective colorimetric and fluorescent turn-on chemosensor and its application in living cell imaging
Supriti Sen, Titas Mukherjee, Basab Chattopadhyay, Anuradha Moirangthem, Anupam Basu, Jaromir Marek and Pabitra Chattopadhyay
Analyst, 2012, 137, 3975-3981
DOI: 10.1039/C2AN35560D

Silylated BODIPY dyes and their use in dye-encapsulated silica nanoparticles with switchable emitting wavelengths for cellular imaging
Xuehua Hong, Zhuyuan Wang, Jing Yang, Qingdong Zheng, Shenfei Zong, Yu Sheng, Deqin Zhu, Changquan Tang and Yiping Cui
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35389J

Fourier transform infrared imaging analysis in discrimination studies of squamous cell carcinoma
J. D. Pallua, C. Pezzei, B. Zelger, G. Schaefer, L. K. Bittner, V. A. Huck-Pezzei, S. A. Schoenbichler, H. Hahn, A. Kloss-Brandstaetter, F. Kloss, G. K. Bonn and C. W. Huck
Analyst, 2012, 137, 3965-3974
DOI: 10.1039/C2AN35483G

Fabrication of glutathione photoelectrochemical biosensor using graphene–CdS nanocomposites
Xiaomei Zhao, Shiwei Zhou, Qingming Shen, Li-Ping Jiang and Jun-Jie Zhu
Analyst, 2012, 137, 3697-3703
DOI: 10.1039/C2AN35658A

BODIPY based colorimetric fluorescent probe for selective thiophenol detection: theoretical and experimental studies
Dnyaneshwar Kand, Pratyush Kumar Mishra, Tanmoy Saha, Mayurika Lahiri and Pinaki Talukdar
Analyst, 2012, 137, 3921-3924
DOI: 10.1039/C2AN35524H

Quantification of low-polar small molecules using room temperature ionic liquids matrix-assisted desorption corona beam ionization
Hua Wang, Yongning Wu, Bin Guo, Wenjian Sun, Li Ding and Bo Chen
Analyst, 2012, 137, 3982-3988
DOI: 10.1039/C2AN35508F

Silver nanoparticle aggregates on copper foil for reliable quantitative SERS analysis of polycyclic aromatic hydrocarbons with a portable Raman spectrometer
Xiaohong Jiang, Yongchao Lai, Min Yang, Heng Yang, Wei Jiang and Jinhua Zhan
Analyst, 2012, 137, 3995-4000
DOI: 10.1039/C2AN35713E

A BODIPY-functionalized bimetallic probe for sensitive and selective color-fluorometric chemosensing of Hg²⁺
Hyunjong Son, Ji Ha Lee, Yang-Rae Kim, In Su Lee, Sanyang Han, Xiaogang Liu, Justyn Jaworski and Jong Hwa Jung
Analyst, 2012, 137, 3914-3916
DOI: 10.1039/C2AN35704F

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HOT articles in Issue 17

01 Aug 2012

By Vibhuti Patel, Deputy Editor.

BODIPY-functionalized bimetallic probe for sensitive and selective color-fluorometric chemosensing of mercury

Son et al., Analyst, 2012, 137, 3914-3916

As well as the cover articles, we have a good helping of HOT articles for you in our latest issue.

These include a paper from Advisory Board member Kemin Wang and colleagues on a novel, simple and cost-effective fluorometric DNA polymerase detection method which utilizes graphene oxide as a signal switch.

There’s also a new BODIPY dye conjugate for selective quenching of mercury (see the colourful graphical abstract to the left) from researchers in Korea and Singapore.

Take a look at all the HOTs below – free to access for the next 2 weeks.

Read more »

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Issue 17 now online

31 Jul 2012

By Vibhuti Patel, Deputy Editor.

Analyst 2012, Vol. 136, Issue 17, front cover

Front cover: Branagan & Bohn, Analyst, 2012, 137, 3932-3939

Take a look at the latest issue of Analyst, with two great covers and host of HOT articles for you to enjoy.

The front cover features a HOT paper from our Editorial Board Chair, Paul Bohn, and his post-doc Sean Branagan. Paul and Sean demonstrate electrochemical imaging using enhanced optical transmission (EC-EOT) by applying it to several categories of electrochemical processes, using a spectral mapping technique that can be miniaturized. They say that in future applications, the enhanced spectral information offered by EOT may be useful for separating faradaic- and non-faradaic electrochemical signals as well as spatially resolving phenomena occurring at different locations relative to the electrified interface.

Plasmonic response of electrified metal–liquid interfaces during faradaic and non-faradaic reactions by enhanced optical transmission
Sean P. Branagan and Paul W. Bohn
Analyst, 2012,137, 3932-3939
DOI: 10.1039/C2AN35488H

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RSC Thermal Methods Group Event: 21st Nov 2012

26 Jul 2012

By Rebecca Brodie, Deputy Editor.

The RSC Thermal Methods Group are pleased to announce the date for their next event.

RSC Thermal Methods Group
Living and Breathing Calorimetry: Biological & Biopharmaceutical Applications of Isothermal Calorimetry
GlaxoSmithKline Ware
21st November 2012

This 1 day event offers an opportunity for attendees to hear the acceptance lecture that will be given by Prof. Beezer upon receipt of the Setaram-ICTAC award for Calorimetry at the ICTAC 2012 Congress in Japan. The meeting will also bring together a number of the world’s foremost practitioners of isothermal calorimetry who will explain the use of the technique in studying biological and biopharmaceutical materials.

More Information: Group Website
Contact: Dr Catherine Barnes, 01279633125, Catherine.x.barnes@gsk.com

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An amazing experience at the Gordon Research Conference on Bioanalytical Sensors

24 Jul 2012

By Vibhuti Patel, Deputy Editor.

By Pui Sai Lau, Web Writer

For anyone working in the area of sensing who is interested in attending a scientific conference in the near future, I strongly recommend att ending the GRC on Bioanalytical Sensors. Having attended two GRCs already, what I appreciate most about the GRC format is finding out about the latest discoveries, as much of the work presented is typically unpublished. Also, from my experiences, the conference set-up has been well-organized, the food superb and the location phenomenal! This year’s meeting was at Salve Regina University, Newport, Rhode Island, USA and was chaired by Steven Soper, supported by Vice-Chairs Susan Lunte and Paul Cremer.

Though several weeks have passed, I am still reflecting on much of the science that I have learned. The conference theme was focused on biosensor development, but the topics presented were diverse ranging from nanotechnology to microfluidics and engineered surfaces. While I am not permitted to reveal specifics presented at the conference, I must say I left inspired and have conjured up some potential collaborative ideas.

Participants of the GRC on Bioanalytical Sensors

It was also a great pleasure meeting fellow members of the biosensor community, and I have become good friends with some individuals whom I’ve met before. I also had the opportunity to meet many new people, including Vibhuti Patel, Deputy Editor for Analyst and Analytical Methods. As I am highly interested in potentially pursuing a career in editing and publishing, I was eager to ask Vibhuti about her job during a social hour. Vibhuti was very kind and patient to answer my many questions, and even offered me a position as a web writer for Analyst and Analytical Methods – journals that I already admire for publishing the latest, novel ideas in analytical, and bioanalytical sciences. So here I am, blogging for the RSC and delighted to be part of the team! Check out Vibhuti’s blog post for her thoughts on the GRC experience and links to some interesting papers recently published in RSC journals from fellow conference attendees.

Note: Thanks for the lovely comments, Pui Sai; glad to have met you and very pleased to have you as part of the team! Look out for more posts from Pui Sai in the near future. – Vibhuti

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HOT Article: En route to convenient point-of-care diagnosis for diabetics

24 Jul 2012

By Rebecca Brodie, Deputy Editor.

Post written by web writer Pui Sai Lau, McMaster University, Canada

Devadhasan & Kim, Analyst, 2012, Advance Article

Today millions of people suffer from type I and type II diabetes, and the associated mortality rate is on the rise. Diagnostic monitoring of glucose is critical to help control blood glucose levels in patients. Currently, various self-monitoring enzymatic strips, and electrochemical sensors are commercially available. However, the high expense, conditional accuracy, and invasiveness are hurdles, which still need to be overcome. Optical detection for glucose monitoring has made significant advancement over the years. Jasmine Pramila Devadhasan and Sanghyo Kim from Gachon University, South Korea have developed a glucose oxidase based sensor using the power of Complementary Metal Oxide Semiconductor (CMOS) imaging to detect glucose levels by photon count variation. Find out more about this discovery below.

Toward CMOS image sensor based glucose monitoring
Jasmine Pramila Devadhasan and Sanghyo Kim
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35458F

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HOT articles in Analyst Issue 16

18 Jul 2012

By Rebecca Brodie, Deputy Editor.

In this Issue 16 of Analyst we have a dozen HOT articles for you to read. Topics range from bacteria detection, VOCs in human saliva, food quality, fluorescence sensing platforms, and glutathione biosensors.

A facile and sensitive detection of pathogenic bacteria using magnetic nanoparticles and optical nanocrystal probes

Jeon et al., Analyst, 2012, 137, 3609

All these papers will be free to access for 2 weeks.

A facile and sensitive detection of pathogenic bacteria using magnetic nanoparticles and optical nanocrystal probes
Jinmyoung Joo, Changyong Yim, Donghoon Kwon, Jaejin Lee, Hwa Hui Shin, Hyung Joon Cha and Sangmin Jeon
Analyst, 2012, 137, 3609
DOI: 10.1039/C2AN35369E

Direct ionization of biological tissue for mass spectrometric analysis
Bin Hu, Ying-Han Lai, Pui-Kin So, Huanwen Chen and Zhong-Ping Yao
Analyst, 2012, 137, 3613
DOI: 10.1039/C2AN16223G

Sampling and characterisation of volatile organic compound profiles in human saliva using a polydimethylsiloxane coupon placed within the oral cavity
Helen J. Martin, Svetlana Riazanskaia and C. L. Paul Thomas
Analyst, 2012, 137, 3627
DOI: 10.1039/C2AN35432B

Monitoring of chicken meat freshness by means of a colorimetric sensor array
Yolanda Salinas, José V. Ros-Lis, José-L. Vivancos, Ramón Martínez-Máñez, M. Dolores Marcos, Susana Aucejo, Nuria Herranz and Inmaculada Lorente
Analyst, 2012, 137, 3635
DOI: 10.1039/C2AN35211G