HOT papers in Analyst Issue 10

Enjoy our new HOT papers free for you to read until May 15th. Click on the links below:

Analyst Issue 10

Study of receptor mediated selective anion transmembrane transport using parallel artificial membrane permeability assay
Lenka Veverková, Kamil Zárubaa and   Vladimír Král
Analyst, 2013,138, 2804-2807
DOI: 10.1039/C3AN36760F

LED-induced in-column molecular imprinting for solid phase extraction/capillary electrophoresis
Xinfeng Zhang, Shuxia Xu, Yong-Ill Lee and   Steven A. Soper
Analyst, 2013,138, 2821-2824
DOI: 10.1039/C3AN00257H

Radical induced disulfide bond cleavage within peptides via ultraviolet irradiation of an electrospray plume
Craig A. Stinson and   Yu Xia
Analyst, 2013,138, 2840-2846
DOI: 10.1039/C3AN00303E

Detection of factor IX using PEG-based blocking agents

A dual channel optical detector for trace water chemodosimetry and imaging of live cells
Guangwen Men, Guirong Zhang, Chunshuang Liang, Huiling Liu, Bing Yang, Yuyu Pan, Zhenyu Wang and   Shimei Jiang
Analyst, 2013,138, 2847-2857
DOI: 10.1039/C3AN36887D

An in situ spatially resolved analytical technique to simultaneously probe gas phase reactions and temperature within the packed bed of a plug flow reactor
Jamal Touitou, Robbie Burch, Christopher Hardacre, Colin McManus, Kevin Morgan, Jacinto Sá and   Alexandre Goguet
Analyst, 2013,138, 2858-2862
DOI: 10.1039/C3AN00250K

A high-performance waveguide-mode biosensor for detection of factor IX using PEG-based blocking agents to suppress non-specific binding and improve sensitivity
Thangavel Lakshmipriya, Makoto Fujimaki, Subash C. B. Gopinath, Koichi Awazu, Yukichi Horiguchi and   Yukio Nagasaki  
Analyst, 2013,138, 2863-2870
DOI: 10.1039/C3AN00298E

Probing site-exclusive binding of aqueous QDs and their organelle-dependent dynamics in live cells by single molecule spectroscopy
Chaoqing Dong, Basudev Chowdhury and   Joseph Irudayaraj 
Analyst, 2013,138, 2871-2876
DOI: 10.1039/C3AN36906D

A thin-layered chromatography plate prepared from naphthalimide-based receptor immobilized SiO2 nanoparticles as a portable chemosensor and adsorbent for Pb2+
Sunhong Park, Jin Hyeok Lee and   Jong Hwa Jung  
Analyst, 2013,138, 2812-2815
DOI: 10.1039/C3AN00292F

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RSC Grants for the 44th IUPAC World Chemistry Congress

£400 bursaries for ten UK-based PhD student and early career researcher members provided by the RSC to participate in the 44th IUPAC World Chemistry Congress in Istanbul, Turkey, 11-16 August 2013.

 

The main topic of this year’s congress is “Clean Energy Through Chemistry”. Speakers include Daniel Nocera from Harvard and Martin Quack from ETH Zurich. For more details, please see http://www.iupac2013.org/.

To apply for this grant, please complete the application form (my.rsc.org/content/images/Science/IUPAC-application.pdf) and include a copy of your CV by noon on Friday the 26th April. Applications should be sent to science@rsc.org.

Please note that the registration deadline for IUPAC 2013 is the 30th April.  Members wishing to apply for an RSC grant will also need to register for the congress via the IUPAC 2013 website (http://www.iupac2013.org/abstract_submissions.asp).

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Analyst Issue 10 now online

Woodin et al., Analyst, 2013, 138, 2793-2803

Welcome to Analyst Issue 10, our new issue featuring all the latest developments in analytical chemistry. Take a look at our beautiful covers and discover all about the new research behind them.

The outside front cover of the issue gives us a snapshot of the interesting Critical Review by Heather Desaire and co-authors at the University of Kansas, USA, who describe the most recent software tools designed for interpreting mass spectrometry data from glycans and glycopeptides. The authors describe how to analyse the composition of released glycans and characterise both N-linked and O-linked glycopeptides.

Software for automated interpretation of mass spectrometry data from glycans and glycopeptides
Carrie L. Woodin, Morgan Maxona and Heather Desaire
Analyst, 2013,138, 2793-2803
DOI: 10.1039/C2AN36042J

Patel et al., Analyst, 138, 2833-2839

Our inside front cover shows the work of Bhavik Anil Patel and colleagues at the University of Brighton, UK. The researchers fabricated and characterised a microelectrode array  for simultaneous multi-site recordings of dopamine release from an isolated single neuron. They observed electrically evoked dopamine release  from the cell body, axonal regions and the terminal. According to the authors, this study provides insights into the signalling mechanisms of neurons and formation of synaptic connections.

A planar microelectrode array for simultaneous detection of electrically evoked dopamine release from distinct locations of a single isolated neuron
Bhavik Anil Patel, Collin C. Luk, Pei Ling Leow, Arthur J. Lee, Wali Zaidic and Naweed I. Syedc  
Analyst, 2013,138, 2833-2839
DOI: 10.1039/C3AN36770C

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HOT articles in Analyst

Chemical interactions and fate of nanoprobes upon entering living cells

Take a look at our new HOT papers free for you to read until May 13th !

Do you know what happens to nanoprobes once they enter living cells? And did you hear about  in-column molecularly imprinted solid phase extraction concentrators for capillary electrophoresis?

To know more about the latest research published in Analyst, click on the links below and enjoy the reading!

LED-induced in-column molecular imprinting for solid phase extraction/capillary electrophoresis
Xinfeng Zhang ,  Shuxia Xu ,  Yong-Ill Lee and Steven A. Soper
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00257H

New light emitting diode polymerization technology

A thin-layered chromatography plate prepared from naphthalimide-based receptor immobilized SiO2 nanoparticles as a portable chemosensor and adsorbent for Pb2+
Sunhong Park ,  Jin Hyeok Lee and Jong Hwa Jung
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00292F

Off-line reaction monitoring of the oxidation of alkenes in water using drop coating deposition Raman (DCDR) spectroscopy
Shaghayegh Abdolahzadeh ,  Nicola M. Boyle ,  Apparao Draksharapu ,  Andrew C. Dennis ,  Ronald Hage ,  Johannes W. de Boer and Wesley R. Browne
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00330B

Probing site-exclusive binding of aqueous QDs and their organelle-dependent dynamics in live cells by single molecule spectroscopy
Chaoqing Dong,a   Basudev Chowdhurya and   Joseph Irudayaraj*a  
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN36906D

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Top ten most accessed articles in February

This month sees the following articles in Analyst that are in the top ten most accessed:-

Lipid imaging by mass spectrometry – a review 
David Godea, Dietrich A. Volmer 
Analyst, 2013,138, 1289-1315 
DOI: 10.1039/C2AN36337B  

Carbon nanotube immobilized polar membranes for enhanced extraction of polar analytes 
Madhuleena Bhadraa and Somenath Mitra 
Analyst, 2012,137, 4464-4468 
DOI: 10.1039/C2AN35619H  

Antibody orientation on biosensor surfaces: a minireview 
Anke K. Trilling, Jules Beekwildera and Han Zuilhof 
Analyst, 2013,138, 1619-1627 
DOI: 10.1039/C2AN36787D  

A novel near-infrared fluorescent probe for selectively sensing nitroreductase (NTR) in an aqueous medium 
Youmin Shi, Sichun Zhang and Xinrong Zhang 
Analyst, 2013,138, 1952-1955 
DOI: 10.1039/C3AN36807F  

Protein amyloids develop an intrinsic fluorescence signature during aggregation 
Fiona T. S. Chan, Gabriele S. Kaminski Schierle, Janet R. Kumita,  Carlos W. Bertoncini, Christopher M. Dobson and Clemens F. Kaminski 
Analyst, 2013,138, 2156-2162 
DOI: 10.1039/C3AN36798C  

Fabrication of Cr doped SnO2 nanoparticles based biosensor for the selective determination of riboflavin in pharmaceuticals 
N. Lavanya, S. Radhakrishnan, C. Sekar, M. Navaneethanb and Y. Hayakawa 
Analyst, 2013,138, 2061-2067 
DOI: 10.1039/C3AN36754A  

A quantum dot-based “off–on” fluorescent probe for biological detection of zinc ions 
Hu Xu, Zhiping Wang, Yan Li, Shijian Ma, Peiyi Hua and Xinhua Zhong 
Analyst, 2013,138, 2181-2191 
DOI: 10.1039/C3AN36742H  

Upconversion nanoparticles in biological labeling, imaging, and therapy 
Feng Wang, Debapriya Banerjee, Yongsheng Liu, Xueyuan Chenc and Xiaogang Liu 
Analyst, 2010,135, 1839-1854 
DOI: 10.1039/C0AN00144A  

Rayleigh, Ramsay, Rutherford and Raman – their connections with, and contributions to, the discovery of the Raman effect 
Robin J. H. Clark 
Analyst, 2013,138, 729-734 
DOI: 10.1039/C2AN90124B  

Protein lysine acetylation analysis: current MS-based proteomic technologies 
Kai Zhang, Shanshan Tianab and Enguo Fan 
Analyst, 2013,138, 1628-1636 
DOI: 10.1039/C3AN36837H  

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Analyst? Then why not submit to us today or alternatively email us your suggestions.

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Using Infrared Spectroscopy to Predict Cancer Origin

Pui Sai Lau is a guest web writer for Analyst. She is currently a PhD student at McMaster University, Hamilton, ON, Canada.

FTIR Based Classification of Carcinoma Regions in Brain Tissue

FTIR based classification of carcinoma regions in brain tissue

Cancer is one of the top causes of death in the world, particularly for developed countries. Regardless of the cancer type, up to 40% of all cases metastasize to the brain during disease progression. Indeed, better survival rates are possible with early and accurate cancer detection.

While histopathologic evaluation involving staining of brain tissue is the current gold standard method for diagnosis, major drawbacks include the complexity of analysis and the non-specific staining of some dyes for non-cancerous cells. Moreover, histopathological staining, and other screening methods often cannot identify the primary tumor of brain metastasis. Without knowledge of the cancer origin, determination of the optimal treatment strategy can be difficult.

Christoph Krafft and colleagues from the Institute of Photonic Technology of Jena, Germany, have developed a strategy to help identify the primary tumor by using Fourier transform infrared (FTIR) and associated software. By analysing brain metastasis tissue, the “molecular fingerprint”, or vibrational spectra characteristic of the primary tumor can be found to deduce the cancer source.

Learn more about this exciting discovery by accessing the link below. This paper will be free to read until April 29th:

Tumor margin identification and prediction of the primary tumor from brain metastases using FTIR imaging and support vector machines
Norbert Bergner ,  Bernd F. M. Romeike ,  Rupert Reichart ,  Rolf Kalff ,  Christoph Krafft and Jürgen Popp
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00326D

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Hot papers in Analyst

Analyst CoverTake a look at our new HOT papers free for you to discover all about!
They cover a wide range of topics including the development a ruthenium-based smart probe for selective recognition of cations using a single optical technique and the optimization of a neuraminidase assay successfully integrated into a single-step operation. To read the full papers, please access the links below.
They will be free to read until April 29th.

A stimuli-responsive “smart probe” for selective monitoring of multiple-cations via differential analyses
Anup Kumar ,  Alok K. Singh and Tarkeshwar Gupta
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00087G

A dual channel optical detector for trace water chemodosimetry and imaging of live cells
Guangwen Men ,  Guirong Zhang ,  Chunshuang Liang ,  Huiling Liu ,  Bing Yang ,  Yuyu Pan ,  Zhenyu Wang and Shimei Jiang
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN36887D

Spectral cytopathology: new aspects of data collection, manipulation and confounding effects
Miloš Miljković ,  Benjamin Bird ,  Kathleen Lenau ,  Antonella I. Mazur and Max Diem
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00185G

Integration of neuraminidase inhibitor assay into a single-step operation using a combinable poly(dimethylsiloxane) capillary sensor
Tadashi Ishimoto ,  Kaede Jigawa ,  Terence G. Henares ,  Tatsuro Endo and Hideaki Hisamoto
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN36785A

A high-performance waveguide-mode biosensor for detection of factor IX using PEG-based blocking agents to suppress non-specific binding and improve sensitivity
Thangavel Lakshmipriya ,  Makoto Fujimaki ,  Subash C. B. Gopinath ,  Koichi Awazu ,  Yukichi Horiguchi and Yukio Nagasaki
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00298E

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2013 ANACHEM Award

2013 ANACHEM Award
Call for Nominations

 

The Association of Analytical Chemistry, ANACHEM, is seeking nominations for the 2013 ANACHEM Award. The award honors an outstanding analytical chemist who has made significant contributions to the advancement of analytical chemistry. Consideration will be given not only to the importance of the candidate’s reaserch but to other contributions such as mentoring students, service to the professional community, and service as a scientist to society in general.

The ANACHEM award will be presented at the FACSS: SCIX 2013 meeting in Milwaukee, WI, September 29 – October 4, 2013. The ANACHEM award consists of $1,000 and travel expenses to the conference.

Nominators should send the CV of the nominee and two nomination letters. Self-nominations are allowed. Nominee is expected to be present at the meeting at which the award is presented and give the keynote lecture the following year at the Annual ANACHEM/SAS Conference in Detroit, MI.

Nominations should be sent to: tmathews@chem.wayne.edu

Deadline: Friday, April 26, 2013

Contact Information:
Dr. Tiffany A. Mathews
2013 ANACHEM Award Chair
Wayne State University
5101 Cass Ave.
Detroit, MI 48377
Email: tmathews@chem.wayne.edu

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HOT Articles in Analyst

Take a look at the HOT papers recently published in Analyst! They include a wide variety of topics, from the use of Raman spectroscopy for detection of cancer and malaria to the development of new analytical techniques to probe gas phase reactions and temperatures. These papers will be free to read until April 19th. Have a read now!

SERS analysis blood test for non invasive cervical cancer detection

Blood plasma surface-enhanced Raman spectroscopy for non-invasive optical detection of cervical cancer
Shangyuan Feng ,  Duo Lin ,  Juqiang Lin ,  Buhong Li ,  Zufang Huang ,  Guannan Chen ,  Wei Zhang ,  Lan Wang ,  Jianji Pan ,  Rong Chen and Haishan Zeng
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN36890D

Raman spectroscopic analysis of malaria disease progression via blood and plasma samples
Alison J. Hobro ,  Aki Konishi ,  Cevayir Coban and Nicholas I. Smith
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00255A

Raman spectroscopiuc analysis of malaria disease

Radical induced disulfide bond cleavage within peptides via ultraviolet irradiation of an electrospray plume
Craig A. Stinson and Yu Xia
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00303E

An in situ spatially resolved analytical technique to simultaneously probe gas phase reactions and temperature within the packed bed of a plug flow reactor
Jamal Touitou ,  Robbie Burch ,  Christopher Hardacre ,  Colin McManus ,  Kevin Morgan ,  Jacinto Sá and Alexandre Goguet
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00250K

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Analyst Issue 9 now online

Collins et al., Analyst, 2013, 138, 2540-2545

 Analyst Issue 9 is finally available online! Take a look at our great new covers and read all about the research behind them.

The outside front cover showcases research from the Dublin City University, Ireland. In this work, David Collins and colleagues present a non-invasive, in-process measurement of the layer growth during laminar flow polymerisation and discuss its application to existing methods for the fabrication of monoPLOT columns through both photo and thermal initiation.

In-process phase growth measurement technique in the fabrication of monolithic porous layer open tubular (monoPLOT) columns using capacitively coupled contactless conductivity
David A. Collins ,  Ekaterina P. Nesterenko ,  Dermot Brabazon and Brett Paull
Analyst, 2013,138, 2540-2545
DOI: 10.1039/C3AN00133D

Lai et al., Analyst, 2013, 138, 2598-2603

Our inside front cover shows the work of Jinhua Zhan and his team from the Shandong University in China. The researchers describe how SERS active extraction column-based on alkanethiols modified  silver dendrites facilitate analysis with high reliability and accuracy. According to the authors, this SERS-active extraction column combines the advantages of both SPE and SERS.

Combination of solid phase extraction and surface-enhanced Raman spectroscopy for rapid analysis
Yongchao Lai ,  Jingcheng Cui ,  Xiaohong Jiang ,  Sha Zhu and Jinhua Zhan
Analyst, 2013,138, 2598-2603
DOI: 10.1039/C3AN36700B

Tanaka et al., Analyst, 2013, 138, 2536-2539

Finally, the outside cover of this issue features interesting research on surface-enhanced photochromism. The study led by Kenta Adachi at Yamaguchi University shows the surface-enhanced photochromic phenomena by L-phenylalanine adsorbed on tungsten(VI) oxide (WO3) nanoparticles in the aqueous solution. The authors propose photochromic WO3 nanoparticles as highly effective colorimetric sensor probes for amino acids and related compounds.

Surface-enhanced photochromic phenomena of phenylalanine adsorbed on tungsten oxide nanoparticles: a novel approach for “label-free” colorimetric sensing
Shohei Tanaka ,  Kenta Adachi and Suzuko Yamazaki
Analyst, 2013,138, 2536-2539
DOI: 10.1039/C3AN36650B

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