Archive for the ‘Uncategorized’ Category

44th International Symposium on High Performance Liquid Phase Separations and Related Techniques

Graphical Abstract


The 44th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2016) is due to take place at the Marriott San Francisco Marquis, CA between 19th – 24th June 2016.

‘The goal of HPLC 2016 is to bring together scientists who use and develop HPLC, capillary electrophoresis, supercritical fluidic chromatography, microfluidics, and mass spectrometry to exchange ideas, best practices, and latest developments.’

Dates for your diary:

April 11th 2016: Abstract deadline for Poster Presentations
April 18th 2016: Registration and fee payment deadline for presenting author
April 18th 2016: Final program posted online
May 1st 2016: Deadline for reduced registration fees
June 1st 2016: Final deadline to submit late-breaking posters to the online program

SUBMIT YOUR ABSTRACT HERE

For more information about the conference and to register your interest please see their website: HPLC2016.org

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Test to tell if your mince is telling porkies

Graphical AbstractScientists in the UK are battling food fraud with a new quantitative method for detecting pork in beef mince using metabolic fingerprints.
‘Doping beef mince with cheaper pork meat has become a common practice for economic gain,’ explains team member Drupad Trivedi, from Roy Goodacre’s group at the University of Manchester. Though this in itself is not life-threatening, doping and mislabeling meat raises significant ethical and religious concerns.

Meat, the metabolites: an integrated metabolite profiling and lipidomics approach for the detection of the adulteration of beef with pork
Drupad Trivedi, Katherine Anne Hollywood, Nicholas John William Rattray, Holli Ward, Joseph Greenwood, David I. Ellis and Royston Goodacre
Analyst, 2016, Accepted Manuscript
DOI: 10.1039/C6AN00108D, Paper

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Uncoiling collagen using advanced computers

Graphical Abstract
British and French researchers have used modern computing power to enhance mass spectrometry and analyse an extremely complex collagen molecule in a short time scale.

Two-dimensional Fourier transform ion cyclotron resonance mass spectrometry (2D FT-ICR MS), developed in the 1980s, links the mass-to-charge ratios of precursors and fragments in complex samples. Compared to tandem mass spectrometry, 2D FT-ICR MS does not require isolated precursors and shows better resolution. Its applications have been limited, however, due to a lack of sophisticated computers.

Read the full article in Chemistry World >>>


H. J. Simon, M. A. van Agthoven, P. Y. Lam, F. Floris, L. Chiron, M.-A. Delsuc, C. Rolando, M. P. Barrow and P. B. O’Connor
Analyst, 2016, Advance Article
DOI: 10.1039/C5AN01757B, Paper

Do you fancy submitting an article to Analyst? Why not submit to us here today or alternatively email us with your suggestions!

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HOT articles in Analyst

Take a look at our most recent HOT Analyst articles, these are now free to access for the next few weeks!

Graphical Abstract

Superposition of an AC Field improves the discrimination between peptides in nanopore analysis.
Elisabet Jakova and Jeremy S. Lee
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02180K

Versatile G-quadruplex-Mediated Strategies in Label-Free Biosensors and Logic Systems
Jiangtao Ren, Tianshu Wang, Erkang Wang and Jin Wang
Analyst, 2015,140, 2556-2572
DOI: 10.1039/C4AN02282C

Label-free and highly sensitive electrochemiluminescent biosensing using quantum dots/carbon nanotubes in ionic liquid
Wenwen Tu, Xuelin Fang, Jing Lou and Zhihui Dai
Analyst, 2015, 140, 2603-2607
DOI: 10.1039/C4AN02129K

Analysis of fast channel blockage: revealing substrate binding in the microsecond range
Igor Bodrenko, Harsha Bajaj, Paolo Ruggerone, Mathias Winterhalter and Matteo Ceccarelli
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02293A

The potential of chiroptical and vibrational spectroscopies of blood plasma for the discrimination between colon cancer patients and the control group
Michal Tatarkovič, Michaela Miškovičová, Lucie Šťovíčková, Alla Synytsya, Luboš Petruželka and Vladimír Setnička
Analyst, 2015, 140, 2287-2293
DOI: 10.1039/C4AN01880J

Drop-by-Drop Chemical Reaction and Sample Introduction for Capillary Electrophoresis

Fengming Chen, Ying Rang, Ying Weng, Luyao Lin, Hulie Zeng, Hizuru Nakajim, Jin-Ming Lin and Katsumi Uchiyama
Analyst, 2015, Advance Article
DOI: 10.1039/C5AN00040H
Graphical Abstract
The role of lipid droplets and adipocytes in cancer. Raman imaging of cell cultures: MCF10A, MCF7, MDA-MB-231 compared to adipocytes in cancerous human breast tissue
Halina Abramczyk, Jakub Surmacki, Monika Kopeć, Alicja Klaudia Olejnik, Katarzyna Lubecka-Pietruszewska and Krystyna Fabianowska-Majewska
Analyst, 2015, 140, 2224-2235
DOI: 10.1039/C4AN01875C

Label-Free Free-Solution Nanoaperture Optical Tweezers for Single Molecule Protein Studies
Ahmed A. Al Balushi, Abhay Kotnala, Skyler Wheaton, Ryan M. Gelfand, Yashaswini Rajashekara and Reuven Gordon
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02213K

A step towards Mobile Arsenic measurement for surface waters

C. A. de Villiers, M. C. Lapsley and E. A. H. Hall
Analyst, 2015, 140, 2644-2655
DOI: 10.1039/C4AN02368D

Gold nanorod-based localized surface plasmon resonance platform for the detection of environmentally toxic metal ions
Subramaniam Jayabal, Alagarsamy Pandikumar, Hong Ngee Lim, Ramasamy Ramaraj, Tong Sun and Nay Ming Huang
Analyst, 2015, 140, 2540-2555
DOI: 10.1039/C4AN02330G

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Cocaine users sweat over fingerprint analysis

Graphical Abstract

Scientists in the UK and the Netherlands have revealed a rapid, single-fingerprint test for cocaine use. The procedure is less invasive, more hygienic and faster than established approaches, which typically test blood, urine or saliva. Portable versions could be available to law enforcement agencies within the next decade.

Have you recently taken an illicit drug? You have the right to remain silent, but if authorities really need an answer, there’s a global testing industry worth several billion dollars on hand to help, with an array of analytical techniques. Potentially adding to this arsenal, a team of scientists led by Melanie Bailey at the University of Surrey have now demonstrated a formidable test for cocaine – don’t sweat, it only needs one fingerprint.

Read the full article in Chemistry World >>


Rapid detection of cocaine, benzoylecgonine and methylecgonine in fingerprints using surface mass spectrometry
Melanie J. Bailey, Robert Bradshaw, Simona Francese, Tara L. Salter, Catia Costa, Mahado Ismail, Roger P. Webb, Ingrid Bosman, Kim Wolff and Marcel de Puit
Analyst, 2015, Advance Article
DOI: 10.1039/C5AN00112A

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Photoacoustic nanoparticles highlight uranium in the body

Graphical Abstract

Nanoparticles that can be detected with photoacoustic imaging when they complex with uranium ions could open the door to new plans of action after radiological incidents, like Chernobyl or Fukushima, US researchers claim.

Ultrasound imaging is a well-known technique – it’s used during pregnancy and to assess joint injuries, amongst other things. The basics are simple: sound comes in and sound comes out; the difference in backscattered sound is turned into an image. Analogously, in photoacoustic procedures a pulse of light goes in and some of its energy is absorbed. This energy heats the local area and produces a pressure wave as it expands, which is measured acoustically.

Read the full article in Chemistry World >>


Parts per billion detection of uranium with a porphyrinoid-containing nanoparticle and in vivo photoacoustic imaging
I-Ting Ho, Jonathan L. Sessler, Sanjiv Sam Gambhir and Jesse V. Jokerst
Analyst, 2015, Advance Article
DOI: 10.1039/C5AN00207A

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HOT articles in Analyst

Take a look at our most recent HOT Analyst articles, these are now free to access for the next few weeks!

Graphical Abstract

Rapid biodiagnostic ex vivo imaging at 1 μm pixel resolution with thermal source FTIR FPA
C. R. Findlay, R. Wiens, M. Rak, J. Sedlmair, C. J. Hirschmugl, Jason Morrison, C. J. Mundy, M. Kansiz and K. M. Gough
Analyst, 2015, 140, 2493-2503
DOI: 10.1039/C4AN01982B

Controlled growth of immunogold for amplified optical detection of aflatoxin B1
Xu Wang, Reinhard Niessner and Dietmar Knopp
Analyst, 2015, 140, 1453-1458
DOI: 10.1039/C4AN02281E

A Comparative Study of Graphene-Hydrogel Hybrid Bionanocomposites for Biosensing

S. L. Burrs, D. C. Vanegas, M. Bhargava, N. Mechulan, P. Hendershot, H. Yamaguchi, C. Gomes and E. S. McLamore
Analyst, 2015, 140, 1466-1476
DOI: 10.1039/C4AN01788A

Pre-Equlibration Kinetic Size-Exclusion Chromatography with Mass Spectrometry Detection (peKSEC-MS) for Label-Free Solution-Based
Jiayin Bao, Svetlana M. Krylova, Leonid T. Cherney, J. C. Yves Le Blanc, Patrick Pribil, Philip E. Johnson, Derek J. Wilson and Sergey N. Krylov
Analyst, 2015, 140, 990-994
DOI: 10.1039/C4AN02232G

Forensic determination of blood sample age using a bioaffinity-based assay
Juliana Agudelo, Crystal Huynh and Jan Halámek
Analyst, 2015, 140, 1411-1415
DOI: 10.1039/C4AN02269F
Graphical Abstract
Oxidative damage in DNA bases revealed by UV Resonant Raman spectroscopy

Francesco D’Amico, Francesca Cammisuli, Riccardo Addobbati, Clara Rizzardi, Alessandro Gessini, Claudio Masciovecchio, Barbara Rossi and Lorella Pascolo
Analyst, 2015, 140, 1477-1485
DOI: 10.1039/C4AN02364A

The lipid-reactive oxygen species phenotype of breast cancer. Raman spectroscopy and mapping, PCA and PLSDA for invasive ductal carcinoma and invasive lobular carcinoma. Molecular tumorigenic mechanis
Jakub Surmacki, Beata Brozek-Pluska, Radzislaw Kordek and Halina Abramczyk
Analyst, 2015, 140, 2121-2133
DOI: 10.1039/C4AN01876A

Self-cleaning properties in engineered sensors for dopamine electroanalytical detection

Guido Soliveri, Valentina Pifferi, Guido Panzarasa, Silvia Ardizzone, Giuseppe Cappelletti, Daniela Meroni, Katia Sparnacci and Luigi Falciola
Analyst, 2015, 140, 1486-1494
DOI: 10.1039/C4AN02219J

Near-infrared excited ultraviolet emitting upconverting phosphors as an internal light source in dry chemistry test strips for glucose sensing
T. Valta, V. Kale, T. Soukka and C. Horn
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02028F

Micromotors to capture and destroy anthrax simulant spores
Jahir Orozco, Guoqing Pan, Sirilak Sattayasamitsathit, Michael Galarnyk and Joseph Wang
Analyst, 2015, 140, 1421-1427
DOI: 10.1039/C4AN02169J

Compact 3D-Printed Interface for Coupling Open Digital Microchips with Venturi Easy Ambient Sonic-Spray Ionization Mass Spectrometry
Jie-Bi Hu, Ting-Ru Chen, Chia-Hsien Chang, Ji-Yen Cheng, Yu-Chie Chen and Pawel L. Urban
Analyst, 2015, 140, 1495-1501
DOI: 10.1039/C4AN02220C

Rapid Microstructure Characterization of Polymer Thin Films with 2D-Array Multifocus Raman Microspectroscopy
Ashok Zachariah Samuel, Sohshi Yabumoto, Kenichi Kawamura and Koichi Iwata
Analyst, 2015, 140, 1847-1851
DOI: 10.1039/C4AN01983K
Graphical Abstract
Real-time detection of H5N1 influenza virus through hyperbranched rolling circle amplification

Seyed Vahid Hamidi, Hedayatollah Ghourchian and Gholamreza Tavoosidana
Analyst, 2015, 140, 1502-1509
DOI: 10.1039/C4AN01954G

Nitrogen-Doped Carbon Dots from Plant Cytoplasm as Selective and Sensitive Fluorescent Probes for Detecting P-Nitroaniline in Both Aqueous and Soil Systems
Haoran Yuan, Denian Li, Yan Liu, Xizhe Xu and Chuanxi Xiong
Analyst, 2015, 140, 1428-1431
DOI: 10.1039/C4AN01869A

Simultaneous strain and temperature sensing using slightly tapered optical fiber with inner air-cavity
H. F. Chen, D. N. Wang and Y. Wang
Analyst, 2015, 140, 1859-1862
DOI: 10.1039/C4AN02230K

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Phone camera checks water for arsenic

UK scientists have developed a mobile phone-based system to help people avoid drinking water contaminated with arsenic.1 The phone’s camera measures quantum dot fluorescence in response to arsenic, achieving a limit of detection as low as 5μM.

Approximately 57 million people worldwide encounter As(III) concentrations exceeding the World Health Organization (WHO) recommended maximum of 10μg/L on a regular basis. Chronic exposure to this well known carcinogen and poison, which binds to proteins and impairs cell function, is one of the largest environmental health disasters in the world. Finding a portable, easy-to-use method to measure levels of this most toxic form of arsenic in drinking water is therefore vital.

Read the full article in Chemistry World >>>


A step towards Mobile Arsenic measurement for surface waters
Camille Ann De Villiers, Marta C Lapsley and Elizabeth A H Hall
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C4AN02368D

Do you fancy submitting an article to Analyst? Why not submit to us here today or alternatively email us with your suggestions!

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Self-cleaning sensors see the light

Graphical AbstractScientists in Italy have engineered a cheap and simple electrochemical sensor that cleans itself when exposed to ultraviolet light. Their system offers a route towards self-cleaning electrodes with myriad environmental and biomedical sensing applications – from detecting pollutants in water to monitoring medications in blood.

Open any book on chemical or biological sensors and you’ll find a lot of content on electrochemical devices. This prevalence is testament to the importance and advantages of electrode-based sensing; and electrodes containing nanomaterials are becoming increasingly popular, owing to their high surface-to-volume ratio, which can improve their sensitivity and lower costs.

Read the full article in Chemistry World >>


Self-cleaning properties in engineered sensors for dopamine electroanalytical detection
Guido Soliveri, Valentina Pifferi, Guido Panzarasa, Silvia Ardizzone, Giuseppe Cappelletti, Daniela Meroni, Katia Sparnacci and Luigi Falciola
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02219J

Do you fancy submitting an article to Analyst? Why not submit to us here today or alternatively email us with your suggestions!

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HOT articles in Analyst

Take a look at our most recent HOT Analyst articles, these are now free to access for the next few weeks!

Label-free phenotyping of peripheral blood lymphocytes by infrared imaging
M. Verdonck, S. Garaud, H. Duvillier, K. Willard-Gallo and E. Goormaghtigh
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01855A

Graphical Abstract

PNGase F-mediated incorporation of 18O into glycans for relative glycan quantitation
Wei Zhang, Weiqian Cao, Jiangming Huang, Hong Wang, Ji Wang, Chen Xie and Pengyuan Yang
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02073A

A microelectrochemical biosensor for real-time in vivo monitoring of brain extracellular choline
Keeley L. Baker, Fiachra B. Bolger and John P. Lowry
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02027H

Differentiation of Prostate Cancer from Normal Tissue in Radical Prostatectomy Specimens by Desorption Electrospray Ionization and Touch Spray Ionization Mass Spectrometry
K. S. Kerian, A. K. Jarmusch, V. Pirro, M. O. Koch, T. A. Masterson, L. Cheng and R. G. Cooks
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02039A

Multi-enzyme microreactor-based online electrochemical system for selective and continuous monitoring of acetylcholine
Yuqing Lin, Ping Yu and Lanqun Mao
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02089H

Fluorescence Chemosensors for Hydrogen Sulfide Detection in Biological Systems
Zhi Guo, Guiqiu Chen, Guangming Zeng, Zhongwu Li, Anwei Chen, Jiajia Wang and Longbo Jiang
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01909A

Marker-free automated histopathological annotation of lung tumour subtypes by FTIR-Imaging
Frederik Großerueschkamp, Angela Kallenbach-Thieltges, Thomas Behrens, Thomas Brüning, Matthias Altmayer, Georgios Stamatis, Dirk Theegarten and Klaus Gerwert
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01978D

Universal Electronics for Miniature and Automated Chemical Assays
Pawel L. Urban
Analyst, 2015, Advance Article
DOI:
10.1039/C4AN02013H

Graphical Abstract

Raman microimaging of murine lungs: insight into the vitamin A content
K. M. Marzec, K. Kochan, A. Fedorowicz, A. Jasztal, K. Chruszcz-Lipska, J. Cz. Dobrowolski, S. Chlopicki and M. Baranska
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01881H

Stereospecific recognition and quantitative structure-activity relationship between antibodies and enantiomers: ofloxacin as model hapten
Hongtao Mu, Baoling Wang, Zhenlin Xu, Yuanming Sun, Xinan Huang, Yudong Shen, Sergei A. Eremin, Anatoly V. Zherdev, Boris B. Dzantiev and Hongtao Lei
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02155J

A colorimetric method of analysis for trace amounts of hydrogen peroxide with the use of the nano–properties of Molybdenum disulfide
Xinrong Guo, Yong Wang, Fangying Wu, Yongnian Ni and Serge Kokot
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01950D

Infrared spectral signature of human lymphocyte subpopulations from peripheral blood
N. Wald, A. Legat, C. Meyer, D. E. Speiser and E. Goormaghtigh
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02247E

Screening and mapping pigments in paintings using scanning electrochemical microscopy (SECM)
Antonio Doménech-Carbó, María Teresa Doménech-Carbó, Miguel Silva, Francisco Manuel Valle-Algarra, José Vicente Gimeno-Adelantado, Francisco Bosch-Reig and Rufino Mateo-Castro
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01911C

Transmission versus transflection mode in FTIR analysis of blood plasma: is the EFSW effect the only reason of the observed spectral distortions?
Emilia Staniszewska-Slezak, Anna Rygula, Kamilla Malek and Malgorzata Baranska
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01842G

Multivariate statistical methodologies applied in biomedical Raman spectroscopy: Assessing the validity of partial least squares regression using simulated model datasets.
Mark E. Keating, Haq Nawaz, Franck Bonnier and Hugh J. Byrne
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02167C

A colorimetric nitrite detection system based on Ag@Au nanoparticles with excellent selectivity and high sensitivity
Tianhua Li, Yonglong Li, Yujie Zhang, Chen Dong, Zheyu Shen and Aiguo Wu
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01583E

Flow-through polymerase chain reaction inside a seamless 3D helical microreactor fabricated utilizing a silicone tube and a paraffin mold
Wenming Wu, Kieu The Loan Trinh and Nae Yoon Lee
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01675K

Graphical Abstract

ß-Cyclodextrin functionalised gold nanoclusters as a luminescent probe for the ultrasensitive detection of dopamine
Rui Ban, E. S. Abdel-Halim, Jianrong Zhang and Jun-Jie Zhu
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02161D

In-vivo and continuous measurement of bisulfide in the hippocampus of rat’s brain by on-line integrated microdialysis/droplet-based microfluidic system
Feidan Gu, Xiaoyu Zhou, Xiaocui Zhu, Meiping Zhao, Jie Hao, Ping Yu and Lanqun Mao
Analyst
, 2015, Advance Article
DOI: 10.1039/C4AN01974A, Paper

Infrared imaging of MDA-MB-231 breast cancer cell line phenotypes in 2D and 3D cultures
Margarita Smolina and Erik Goormaghtigh
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01833H

High throughput absorbance spectra of cancerous cells: a microscopic investigation of spectral artifacts
A. Mignolet and E. Goormaghtigh
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01834F

Label-free imaging and identification of typical cells of acute myeloid leukaemia and myelodysplastic syndrome by Raman microspectroscopy
R. Vanna, P. Ronchi, A. T. M. Lenferink, C. Tresoldi, C. Morasso, D. Mehn, M. Bedoni, S. Picciolini, L. W. M. M. Terstappen, F. Ciceri, C. Otto and F. Gramatica
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02127D

Infrared imaging of primary melanoma reveals hints of regional and distant metastases
N. Wald and E. Goormaghtigh
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01831A

Pituitary gland under infrared light – in search of a representative spectrum for homogenous regions
A. Banas, K. Banas, A. Furgal-Borzych, W. M. Kwiatek, B. Pawlicki and M. B. H. Breese
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01985G

Design of molecularly imprinted conducting polymer protein-sensing films via substrate-dopant binding
Elena Komarova, Matt Aldissi and Anastasia Bogomolova
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01965B

Vibrational signatures to discriminate liver steatosis grades
Chengyuan Peng, Franck Chiappini, Slávka Kaščáková, Mélanie Danulot, Christophe Sandt, Didier Samuel, Paul Dumas, Catherine Guettier and François Le Naour
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01679C

Graphical AbstractCompetitive evaluation of data mining algorithms for use in classification of leukocyte subtypes with Raman microspectroscopy
A. Maguire, I. Vega-Carrascal, J. Bryant, L. White, O. Howe, F. M. Lyng and A. D. Meade
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01887G

Loss of the preferential control over the striato-nigral direct pathway by striatal NMDA receptors in a rat model of Parkinson’s disease
Michele Morari and Martina Fantin
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01918K

Infrared Micro-spectroscopy for Cyto-pathological Classification of Esophageal Cells
Douglas Townsend, Miloš Miljković, Benjamin Bird, Kathleen Lenau, Oliver Old, Max Almond, Catherine Kendall, Gavin Lloyd, Neil Shepherd, Hugh Barr, Nick Stone and Max Diem
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01884B

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