Vibhuti Patel, Deputy Editor – Page 7

Author Archive

Issue 19 online

06 Sep 2011

Analyst, 2011, 136(19): 3817-4084

The latest issue of Analyst is now available online.

On the front cover is work from Xuefeng Yin of Zhejiang University and colleagues. One of the major difficulties in microfluidic cell analysis for adherent cells is that the cells are prone to attaching to the channel surface. Yin et al present a simple 3D hydrodynamic focusing microfluidic device integrated with continuous sampling, rapid dynamic lysis, capillary electrophoretic (CE) separation and detection of intracellular content, which aims to overcome this:

Three-dimensional (3D) hydrodynamic focusing for continuous sampling and analysis of adherent cells
Chunxiu Xu, Min Wang and Xuefeng Yin
Analyst, 2011, 136, 3877-3883
DOI: 10.1039/C1AN15019G

The inside front cover highlights research by Srinand Sreevatsan of the University of Minnesota and collaborators from the University of Guelph. Short RNA and DNA sequences (aptamers) have properties that make them desirable as biosensors for bacterial contaminants in food. This paper describes the selection and characterization of a single, dominant aptamer (SSRA1), against the B-chain of the toxin ricin. The results indicate that SSRA1 could serve well as pre-analytical tool for processing of ricin from liquid foods to aid current diagnostics as well as a sensor for direct ricin detection:

A single DNA aptamer functions as a biosensor for ricin
Elise A. Lamont, Lili He, Keith Warriner, Theodore P. Labuza and Srinand Sreevatsan
Analyst, 2011, 136, 3884-3895
DOI: 10.1039/C1AN15352H

Both papers will be free to access for 6 weeks.

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Issue 18 now online

25 Aug 2011

Analyst, 2011, 136(18): 3573-3816

Our latest issue is now available online.

Featured on the front cover is work from Huanwen Chen of East China Institute of Technology and colleagues, who present a straightforward method based on extractive electrospray ionization (EESI) was developed for fishing native proteins from a highly complex biological soup for mass spectrometric analysis without any sample pre-treatment.

Communication: Direct detection of native proteins in biological matrices using extractive electrospray ionization mass spectrometry
Bin Hu, Shuiping Yang, Ming Li, Haiwei Gu and Huanwen Chen
Analyst, 2011, 136, 3599-3601
DOI: 10.1039/C1AN15410A

The inside front cover highlights work from Brian Cunningham and colleagues from the University of Illinois at Urbana Champaign. They introduce photonic crystal enhanced microscopy as a label-free biosensor imaging technique capable of measuring cell surface attachment and attachment modulation.

Label-free imaging of cell attachment with photonic crystal enhanced microscopy
Erich A. Lidstone, Vikram Chaudhery, Anja Kohl, Vincent Chan, Tor Wolf-Jensen, Lawrence B. Schook, Rashid Bashir and Brian T. Cunningham
Analyst, 2011, 136, 3608-3615
DOI: 10.1039/C1AN15171A

Both these articles will be free to access for 6 weeks, so let your colleagues know!

On the back cover is research from the laboratories of Kyubong Jo and Han Bin Oh of Sogang University, Seoul. They systematically studied DNA recognition by zinc-fingers using negative-ion electrospray ionization mass spectrometry.

Zinc-finger motif noncovalent interactions with double-stranded DNA characterized by negative-ion electrospray ionization mass spectrometry
Soojin Park, Kyubong Jo and Han Bin Oh
Analyst, 2011, 136, 3739-3746
DOI: 10.1039/C1AN15376E

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Emerging Investigators issue now online!

09 Aug 2011

Issue 17 is our themed issue on Emerging Investigators, featuring papers from some of the rising stars of analytical science. The aim of this issue was to highlight some of the outstanding young analytical scientists of today, and in doing so capture newly emerging high-impact areas of research – once you’ve taken a look at the papers, we hope you’ll agree that we’ve succeeded in doing this!

The issue is introduced in an Editorial from the Guest Editors: Perdita Barran of the University of Edinburgh and Christy Haynes of the University of Minnesota.

Perdita Barran (L) and Christy Haynes (R)

Editorial: Analyst‘s special focus on Emerging Investigators
Analyst, 2011, 136, 3405-3405
DOI: 10.1039/C1AN90062E

We’d like to thank Perdita and Christy for all their work, and all the authors for giving us such a great collection of papers. You can find out more about all of our Emerging Investigators in our profile piece:

Profile: Contributors to the Emerging Investigators Issue
Analyst, 2011, 136, 3406-3409
DOI: 10.1039/C1AN90056K

The cover images for this issue are as good as the work they represent (yes, I know we have a biased opinion!) The front cover features work from Ryan C. Bailey and Ji-Yeon Byeon in which arrays of silicon photonic microring resonators are used for the simultaneous evaluation of multiple capture agents against the same target antigen.

Analyst, 2011, 136(17): 3393-3572

Communication: Multiplexed evaluation of capture agent binding kinetics using arrays of silicon photonic microring resonators
Ji-Yeon Byeon and Ryan C. Bailey
Analyst, 2011, 136, 3430-3433
DOI: 10.1039/C0AN00853B

The inside front cover showcases a review by Lane A. Baker and Sean P. Bird, focusing on recent advances in the use of hydrogels for chemical and biochemical analysis.

Minireview: Biologically modified hydrogels for chemical and biochemical analysis
Sean P. Bird and Lane A. Baker
Analyst, 2011, 136, 3410-3418
DOI: 10.1039/C0AN00871K

Both these cover articles will be free to access for 6 weeks, so take a look and let your colleagues know.

On the back cover is an image highlighting research from Aydogan Ozcan in the area of lensfree fluorescent on-chip microscopy, which enables rapid imaging of a wide field-of-view without the need for bulky optical or mechanical components or scanners.

Wide-field lensless fluorescent microscopy using a tapered fiber-optic faceplate on a chip
Ahmet F. Coskun, Ikbal Sencan, Ting-Wei Su and Aydogan Ozcan
Analyst, 2011, 136, 3512-3518
DOI: 10.1039/C0AN00926A

We hope that you enjoy this themed issue – please let us know your thoughts by leaving a comment below.

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Graham Cooks to deliver Pittcon 2012 plenary

09 Aug 2011

Prof. Cooks is Henry B. Hass Distinguished Professor–Analytical Chemistry in the Department of Chemistry at Purdue University

We’re delighted that Analyst Editorial Board member, Professor Graham Cooks, will be the plenary speaker at Pittcon 2012.

His talk will be entitled “Ambient Ionization and Mini Mass Spectrometers: In situ MS for Everyone” and will take place at 4.30 p.m. on Sunday 11th March in the Chapin Theater.

Watch this space for more details on our attendance at Pittcon!

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Diagnosing tumours in the nasopharynx without surgery

08 Aug 2011

"Bringing optical histopathology into the clinic would have a huge impact for surgeons, pathologists and patients," says Dr Bevin Lin

Detecting early-stage nasopharyngeal carcinomas via a non-invasive technique which could improve the survival rates of patients has been reported by scientists from Singapore. Diagnosing nasopharyngeal carcinomas before they have become life-threatening is very difficult, with five-year survival rates only around 34 per cent.

A team led by Bevin Lin, from the National University of Singapore, has developed a technique that uses a bifurcated fibre optic probe to collect nasopharyngeal tissue data. By combining ultraviolet auto fluorescence excitation-emission matrix (EEM) spectroscopy and parallel factor analysis calculations, they can then diagnose early-stage carcinomas.

To find out more, including comments from Dr Lin, read Jennifer Newton‘s article in Chemistry World, and access the paper for free using the link below.

Diagnosis of early stage nasopharyngeal carcinoma using ultraviolet autofluorescence excitation–emission matrix spectroscopy and parallel factor analysis
Bevin Lin, Mads Sylvest Bergholt, David P. Lau and Zhiwei Huang
Analyst, 2011
DOI: 10.1039/c1an15525c

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Have you seen the Issue 16 covers?

08 Aug 2011

Analyst, 2011, 136(16): 3205-3392

Just in case you missed them, click below to see the great cover articles from Issue 16.

The front cover features work from Taesung Kim, Sung Kuk Lee and co-workers, describing their microfluidic device that identifies the preferential chemotactic responses of bacterial cells toward carbon sources.

Microfluidic device for analyzing preferential chemotaxis and chemoreceptor sensitivity of bacterial cells toward carbon sources
Minseok Kim, Su Hyun Kim, Sung Kuk Lee and Taesung Kim
Analyst, 2011, 136, 3238-3243
DOI: 10.1039/C1AN15308K

Research by Hua Cui and co-workers on the development of an ultrasensitive ECL aptasensor for protein detection based on a functionalized gold nanoprobe is highlighted on the inside front cover.

A novel electrochemiluminescence aptasensor for protein based on a sensitive N-(aminobutyl)-N-ethylisoluminol-functionalized gold nanoprobe
Ying Chai, Dayong Tian, Jie Gu and Hua Cui
Analyst, 2011, 136, 3244-3251
DOI: 10.1039/C1AN15298J

Both these articles are free for the next 4 weeks, so do take a look and pass on to colleagues.

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Issue 15 online: tackling Grand Challenges

12 Jul 2011

Analyst, 2011, 136(15): 3025-3204

Issue 15 is now available online, and we publish the first of an ongoing collection of articles looking at Grand Challenges in analytical science. In celebration of the International Year of Chemistry, leading scientists (including our own Board members) have put together papers outlining the current challenges faced in analytical science, and how these might be tackled.

There are contributions in this issue from Lloyd Smith, and from Board members Pavel Matousek, Takehiko Kitamori and Facundo Fernandez. Pavel’s minireview is also highlighted on the inside cover.

Minireview: Non-invasive analysis of turbid samples using deep Raman spectroscopy
Kevin Buckley and Pavel Matousek
Analyst, 2011, 136, 3039-3050
DOI: 10.1039/C0AN00723D

Critical Review: Extended nanospace chemical systems on a chip for new analytical technology
Kazuma Mawatari, Takehiko Tsukahara and Takehiko Kitamori
Analyst, 2011, 136, 3051-3059
DOI: 10.1039/C0AN00840K

Critical Review: To understand the whole, you must know the parts: unraveling the roles of protein–DNA interactions in genome regulation
Lloyd M. Smith, Michael R. Shortreed and Michael Olivier
Analyst, 2011, 136, 3060-3065
DOI: 10.1039/C1AN15037E

Poor quality drugs: grand challenges in high throughput detection, countrywide sampling, and forensics in developing countries
Facundo M. Fernandez, Dana Hostetler, Kristen Powell, Harparkash Kaur, Michael D. Green, Dallas C. Mildenhall and Paul N. Newton
Analyst, 2011, 136, 3073-3082
DOI: 10.1039/C0AN00627K

The stunning front cover of this issue highlights work by Jeremy Driskell from the lab of Ralph Tripp. They report the development of a simple, rapid, and sensitive method for quantitative detection of influenza A virus using dynamic light scattering and gold nanoparticle labels.

One-step assay for detecting influenza virus using dynamic light scattering and gold nanoparticles
Jeremy D. Driskell, Cheryl A. Jones, S. Mark Tompkins and Ralph A. Tripp
Analyst, 2011, 136, 3083-3090
DOI: 10.1039/C1AN15303J

Don’t forget that Analyst cover articles are free for 6 weeks!

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Surgeons and patients breathe easy

01 Jul 2011

Breath samples are taken up by the ventilator and sent along a sample line to the mass spectrometer

David Smith from Keele University and colleagues have developed a way of continuously analysing the breath of unconscious patients undergoing surgery using a selected ion flow tube-mass spectrometer (SIFT-MS), which enables measurements to be taken and results to be viewed in the operating theatre.

“Specific breath gases can be monitored that can indicate to the surgeon and anaesthetist the status of the patient, thus allowing more informed decision making and improve the outcome of the surgical procedure,” says Smith.

Read Holly Sheahan’s news story in Chemistry World, and access the communication for free below:

Communication: On-line, real time monitoring of exhaled trace gases by SIFT-MS in the perioperative setting: a feasibility study
Piers R. Boshier, Julia R. Cushnir, Vikash Mistry, Alison Knaggs, Patrik Španěl, David Smith and George B. Hanna
Analyst, 2011, Advance Article
DOI: 10.1039/C1AN15356K

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Highest ever Impact Factor for Analyst!

30 Jun 2011

A new high for Analyst!

We’re delighted to announce that in the 2010 Journal Citation Reports^® from Thomson Reuters, Analyst has an Impact Factor of 3.913 – our highest ever!

Thank you to our Editorial and Advisory Boards, and to all our authors, referees and readers for their contribution to the journal’s success.

We remain committed to publishing the best research in analytical, bioanalytical and detection science and supporting all the communities this encompasses: if you have any comments or suggestions, please let us know by leaving your comments below.

More information on the success of journals across RSC Publishing, take a look at our Publishing Blog.

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Issue 14

29 Jun 2011

Analyst, 2011, 136(14):2869-3024

The latest issue is now online and our covers this time feature work on cancer diagnosis and protein detection.

Work by Christophe A. Marquette and co-workers on an automated multiplex immunoassay involving microarrays of tumor-associated antigens as a proof of concept for cancer diagnosis, is highlighted on the front cover.

Multiplexed immunoassay for the rapid detection of anti-tumor-associated antigens antibodies
C. Desmet, G. C. Le Goff, J.-C. Brès, D. Rigal, L. J. Blum and C. A. Marquette
Analyst, 2011, 136, 2918-2924
DOI: 10.1039/C1AN15121E

The inside front cover features work by Mithran Somasundrum and co-workers on an electrochemical immunoassay platform based on redox-modified carbon nanotube labels for high sensitivity protein detection.

Electrochemical immunoassay platform for high sensitivity protein detection based on redox-modified carbon nanotube labels
Wilanee Chunglok, Porntip Khownarumit, Patsamon Rijiravanich, Mithran Somasundrum and Werasak Surareungchai
Analyst, 2011, 136, 2969-2974
DOI: 10.1039/C1AN15079K

Both articles are free to access for six weeks, so do take a look.

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