Agri Innovation 2015

Join us on 22 April at the Society of Chemical Industry in London for Agri Innovation 2015: Emerging Technologies in Crop Research

This one-day meeting aims to provide an update on several areas of crop research, including identifying target proteins for crop protection ingredients, the synthesis of new crop protection agents and understanding the mechanisms of resistance and immunity in plants and insects. If you are working in organic synthesis, chemical biology or biochemistry in relation to crop science, this meeting will provide an opportunity to catch up on the latest developments. Speakers from academia and industry from across Europe will come together to present and discuss the latest developments in this area.

The meeting is jointly run by the Royal Society of Chemistry, the Society of Chemical Industry Agrisciences Group and AGRI-net, the agriscience chemical biology network. For more details and to register, please visit the website.

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HOT Organic & Biomolecular Chemistry articles

The following Organic & Biomolecular Chemistry articles have all been recommened by the reviewers of the articles as being particularly interesting or particularly significant research. These have all been made free to access until 20th April 2015. The order they appear in the list holds no special meaning or ranking.

Silver catalysed decarboxylative alkylation and acylation of pyrimidines in aqueous media
Wen-Peng Mai, Bin Sun, Li-Qin You, Liang-Ru Yang, Pu Mao, Jin-Wei Yuan, Yong-Mei Xiao and Ling-Bo Qu
DOI: 10.1039/C4OB02524E

10.1039/C4OB02524E


Templating carbohydrate-functionalised polymer-scaffolded dynamic combinatorial libraries with lectins
Clare S. Mahon, Martin A. Fascione, Chadamas Sakonsinsiri, Tom E. McAllister, W. Bruce Turnbull and David A. Fulton
DOI: 10.1039/C4OB02587C

10.1039/C4OB02587C


Oxidative asymmetric umpolung alkylation of Evans’ β-ketoimides using dialkylzinc nucleophiles
Tom A. Targel, Jayprakash N. Kumar, O. Svetlana Shneider, Sukanta Bar, Natalia Fridman, Shimon Maximenko and Alex M. Szpilman
DOI: 10.1039/C4OB02601B

10.1039/C4OB02601B


Cyclopropanation using flow-generated diazo compounds
Nuria M. Roda, Duc N. Tran, Claudio Battilocchio, Ricardo Labes, Richard J. Ingham, Joel M. Hawkins and Steven V. Ley
DOI: 10.1039/C5OB00019J, Communication

10.1039/C5OB00019J


Supramolecular control of transition metal complexes in water by a hydrophobic cavity: a bio-inspired strategy
Olivia Bistri and Olivia Reinaud
DOI: 10.1039/C4OB02511C

10.1039/C4OB02511C


Cyclopenta[b]naphthalene cyanoacrylate dyes: synthesis and evaluation as fluorescent molecular rotors
Laura S. Kocsis, Kristyna M. Elbel, Billie A. Hardigree, Kay M. Brummond, Mark A. Haidekker and Emmanuel A. Theodorakis
DOI: 10.1039/C4OB02563F

10.1039/C4OB02563F


Chiral nanostructuring of multivalent macrocycles in solution and on surfaces
Marco Caricato, Arnaud Delforge, Davide Bonifazi, Daniele Dondi, Andrea Mazzanti and Dario Pasini
DOI: 10.1039/C4OB02643H

10.1039/C4OB02643H


Physicochemical studies on the copper(II) binding by glycated collagen telopeptides
Meder Kamalov, Paul W. R. Harris, Christian G. Hartinger, Gordon M. Miskelly, Garth J. S. Cooper and Margaret A. Brimble
DOI: 10.1039/C4OB02536A
Regiodivergent Lewis base-promoted O- to C-carboxyl transfer of furanyl carbonates
Craig D. Campbell, Caroline Joannesse, Louis C. Morrill, Douglas Philp and Andrew D. Smith
DOI: 10.1039/C4OB02629B

10.1039/C4OB02536A


Total syntheses of five uvacalols: structural validation of uvacalol A, uvacalol B and uvacalol C and disproval of the structures of uvacalol E and uvacalol G
Adiyala Vidyasagar and Kana M. Sureshan
10.1039/C4OB0266310.1039/C4OB02663B B


Direct biosynthetic cyclization of a distorted paracyclophane highlighted by double isotopic labelling of L-tyrosine
Alexandre Ear, Séverine Amand, Florent Blanchard, Alain Blond, Lionel Dubost, Didier Buisson and Bastien Nay
DOI: 10.1039/C5OB00114E

10.1039/C5OB00114E


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HOT Organic & Biomolecular Chemistry articles

The following Organic & Biomolecular Chemistry articles have all been recommened by the reviewers of the articles as being particularly interesting or particularly significant research. These have all been made free to access until 16th March 2015. The order they appear in the list holds no special meaning or ranking.

E. coli cells expressing the Baeyer–Villiger monooxygenase ‘MO14’ (ro03437) from Rhodococcus jostii RHA1 catalyse the gram-scale resolution of a bicyclic ketone in a fermentor
Benjamin D. Summers, Muhiadin Omar, Thomas O. Ronson, Jared Cartwright, Michael Lloyd and Gideon Grogan
DOI: 10.1039/C4OB01441C, Paper
From themed collection In Celebration of Richard Taylor’s 65th Birthday

C4OB01441C GA


Synthesis of unsaturated phosphatidylinositol 4-phosphates and the effects of substrate unsaturation on SopB phosphatase activity
Samuel Furse, LokHang Mak, Edward W. Tate, Richard H. Templer, Oscar Ces, Rüdiger Woscholski and Piers R. J. Gaffney
DOI: 10.1039/C4OB02258K, Paper

C4OB02258K GA


A microwave-assisted multicomponent synthesis of substituted 3,4-dihydroquinazolinones
Marc Y. Stevens, Krzysztof Wieckowski, Peng Wu, Rajiv T. Sawant and Luke R. Odell
DOI: 10.1039/C4OB02417F, Paper

C4OB02417F GA


Near-instant surface-selective fluorogenic protein quantification using sulfonated triarylmethane dyes and fluorogen activating proteins
Qi Yan, Brigitte F. Schmidt, Lydia A. Perkins, Matharishwan Naganbabu, Saumya Saurabh, Susan K. Andreko and Marcel P. Bruchez
DOI: 10.1039/C4OB02309A, Paper

C4OB02309A GA


Bacterial patterning controlled by light exposure
Willem A. Velema, Jan Pieter van der Berg, Wiktor Szymanski, Arnold J. M. Driessen and Ben L. Feringa
DOI: 10.1039/C4OB02483D, Communication

C4OB02483D GA


Exploring the scope of the isothiourea-mediated synthesis of dihydropyridinones
Pei-Pei Yeh, David S. B. Daniels, Charlene Fallan, Eoin Gould, Carmen Simal, James E. Taylor, Alexandra M. Z. Slawin and Andrew D. Smith
DOI: 10.1039/C4OB02408G, Paper

C4OB02408G GA


Energy transfer between amphiphilic porphyrin polymer shells and upconverting nanoparticle cores in water-dispersible nano-assemblies
T. Wu, S. Kaur and N. R. Branda
DOI: 10.1039/C4OB02401J, Paper

C4OB02401J GA


Copper-catalyzed oxidative alkenylation of thioethers via Csp3–H functionalization
Hao Cao, Dong Liu, Chao Liu, Xinquan Hu and Aiwen Lei
DOI: 10.1039/C4OB02564D, Communication

C4OB02564D GA


Volatiles from nineteen recently genome sequenced actinomycetes
Christian A. Citron, Lena Barra, Joachim Wink and Jeroen S. Dickschat
DOI: 10.1039/C4OB02609H, Paper

C4OB02609H GA


Functional chromatographic technique for natural product isolation
Eric C. Lau, Damian J. Mason, Nicole Eichhorst, Pearce Engelder, Celestina Mesa, E. M. Kithsiri Wijeratne, G. M. Kamal B. Gunaherath, A. A. Leslie Gunatilaka, James J. La Clair and Eli Chapman
DOI: 10.1039/C4OB02292K, Communication

C4OB02292K GA

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OBC call for papers: Multivalent Biomolecular Recognition themed issue

Organic & Biomolecular Chemistry is delighted to announce a call for paper for its latest themed issue on: Multivalent Biomolecular Recognition

Guest Editors: Prof.  Mihail Barboiu (Institut Européen des Membranes, France),  Prof. Olof Ramström (KTH – Royal Institute of Technology, Sweden) and Prof. Stéphane Vincent (University of Namur, Belgium)

Submission Deadline: 15th July 2015

From the guest-editors:

The understanding and control of multivalent biomolecular interactions has become one of the key frontiers of chemistry and biology. This issue will cover important findings and advances in the field, in order to:
1. Develop functional sugar decorated nanoplatforms (nanoparticles, nanostructured surfaces, vesicles, microarrays, etc.).
2. Understand the biomolecular mechanisms by exploring their synergistic adaptive interactions with biomolecules, in order to accurately control the chemical/biological responses.

The inspiration for this issue comes partly from our membership of the EU-funded Dynamic Interactive Nanosystems ITN Marie Curie DYNANO Network (see http://www.dynano.eu ). We hope that colleagues from the Network will participate but are also very welcoming to contributors who have not (yet) joined our association.

Research in OBC is published as communications (for urgent work – up to 5 pages in length) or full papers. There is also the opportunity to write a Perspective or Review article for the issue, and if you would be interested in this please let us know. All submissions will be subject to rigorous peer review to meet the usual high standards of OBC.

The deadline for submissions to the themed issue is 15th July 2015, although submissions before this date are of course welcomed.

Manuscripts can be submitted using the RSC’s online submissions service. Please clearly mark that the manuscript is submitted for the themed issue on ‘Multivalent Biomolecular Recognition’.

Please would you inform the editorial office by e-mail as soon as possible if you plan to submit to the issue and whether your contribution will be original research or a review-type article. We would like to have a list of authors who intend to contribute as soon as possible.

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Meet the OBC team – See where and when you can meet us in 2015

A selection of conferences the journal will be attending in 2015.

The Organic & Biomolecular Chemistry team will be attending a number of conferences in 2015 and we would be delighted to meet you there.

We’re also the team behind OBC’s sister journals MedChemComm, Natural Product Reports, and Molecular BioSystems, so we’ll happily discuss your interdisciplinary research work. In fact, many of our authors choose to publish their research across all of these titles.

Spring

National symposium on Chemical Biology 18-19 February 2015, Mysore, India.  Meet Deeksha Gupta.

Directing Biosynthesis IV 25 – 27th March 2015, Norwich, UK. Meet Marie Cote.

MedChemComm, 27-30 April 2015, Hyderabad, India.  Meet Deeksha Gupta.

Grassmere Heterocyclic meeting 7th – 11th May, 2015, Grassmere, UK.  Meet James Anson.

Summer

Royal Society of Chemistry Organic Chemistry Symposium Series 1st – 5th June 2015, Sendai, Tokyo, Kyoto, Japan.  Meet Rich Kelly

American Peptide Symposium 20th – 25th June 2015, Orlando, Florida.  Meet Rich Kelly.

ISMSC 28th June – 2nd July 2015, Strasbourg, France.  Meet Marie Cote.

7th International Conference on Green and Sustainable Chemistry, July 5 – 8th, Tokyo, Japan.  Meet Hiromitsu Urakami.

ESOC 2015 12th – 16th July 2015, Lisbon, Portugal.  Meet Marie Cote.

RSC Organic Synthesis 20th – 23rd July 2015, Cambridge, UK.  Meet James Anson.

9th CCS National Organic Chemistry conference, 31st July to 3rd August 2015, Changchun, China.  Meet Guanqun Song.

9th National Chemical Biology conference, August, Tianjin, China.  Meet Guanqun Song.

250th ACS National Meeting & Exposition 16th – 20th August 2015, Boston, USA.

25th International Society of Heterocyclic Chemistry Conference (August 23-28) in Santa Barbara, USA. Meet Jennifer Lee.

Autumn

18th RSC/SCI medicinal chemistry conference 13th – 16th September 2015, Cambridge, UK.  Meet James Anson.

26th Symposium on Physical Organic Chemistry, 24 – 26th September,  Ehime, Japan.  Meet Hiromitsu Urakami.

13th International Kyoto Conference on New Aspects of Organic Chemistry , 9th  – 13th November, Kyoto, Japan.  Meet Hiromitsu Urakami.

Tateshina Conference, 13th – 15th November, Tateshina, Japan.  Meet Hiromitsu Urakami.

BMOS-16 15th – 19th November 2015, Buzios, Brazil.  Meet Rich Kelly.

Winter

Pacifichem 15th – 20th December 2015, Hawaii, USA.  Meet Marie Cote.

Let us know if you are planning on attending any of these meetings, as we would be happy to meet you there!

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New Editorial Board Chair

Introducing the new Editorial Board Chair for Organic & Biomolecular Chemistry, Professor Andrei Yudin

Prof. Andrei YudinWe are delighted to announce that Professor Andrei Yudin has become the Chair of the Editorial Board for Organic & Biomolecular Chemistry.

For the past 3 years Andrei has been handling manuscripts for OBC as an Associate Editor, but with his move to his new role he will no longer be handling manuscripts himself.

The previous Chair, Professor Jeff Bode, passed over the reins to Andrei at the begining of 2015, and this brings his time on the OBC Editorial Board to a close. Professor Paolo Scrimin’s time on the Editorial Board has also drew to a close at the end of 2014. We would all like to thank both Jeff and Paolo for the many years of service and the invaluable contributions they have made in helping to guide the journal.

About Andrei:

Professor Andrei Yudin obtained his B.Sc. degree at Moscow State University and his Ph.D. degree at the University of Southern California under the direction of Professors G. K. Surya Prakash and George A. Olah. He subsequently took up a postdoctoral position in the laboratory of Professor K. Barry Sharpless at the Scripps Research Institute. In 1998, he started his independent career at the University of Toronto. He received early tenure, becoming an Associate Professor in 2002, and received an early promotion to the rank of a Full Professor in 2007.

Amongst Professor Yudin’s awards are the CSC Award in Combinatorial Chemistry, the 2004 Amgen New Faculty Award, the 2010 CSC Merck-Frosst Therapeutic Center Award, the 2010 Rutherford Medal of the Royal Society of Canada, the 2011 University of Toronto Inventor of the Year Award, and the 2015 Bernard Belleau Award in Medicinal Chemistry. Professor Yudin is a Fellow of the Royal Society of Canada.

Andrei’s Homepage: http://www.chem.utoronto.ca/wp/yudinlab/

Andrei also maintains a science blog – Amphoteros – that aims to illuminate the ongoing synthetic and chemical biology efforts in his lab and to discuss general advances in science, both from the past and present.

Below is his blog following our Editorial Board meeting at the end of last year.

Some news from London

Posted on November 20, 2014

Over the past several days I have been in London, England, where I attended the Fall Board Meeting of Organic and Biomolecular Chemistry. Richard Kelly, the Managing Editor of this RSC publication, has put this meeting together in the Mayfair district of London. Jeff Bode (ETH, Zurich) is stepping down as the Board Chairman and I will be taking over his responsibilities from January 2015. I have to tip my hat off to Jeff for his leadership over the past several years. I have thoroughly enjoyed my role of one of the Associate Editors. The difference now will be that I am no longer going to handle manuscripts, but will instead oversee some strategic areas for growth and improvement. I think this will be very exciting. Earlier this week, I had a lot of fun together with Jeff as well as Ashraf Brik of Ben Gurion University, Margaret Brimble of the University of Aukland, Tony Davis of the University of Bristol, Jonathan Clayden of the University of Manchester, Pauline Chiu of the University of Hong Kong, and Paolo Scrimin of the University of Padova. Unfortunately, Jin-Quan Yu of Scripps was not able to make it to this meeting. Along with Margaret and I, Jin-Quan is one of OBC’s Associate Editors.

In terms of chemistry, I actually wanted to share something that relates to the work of Margaret Brimble (she flew in all the way from New Zealand to meet us). Margaret brought along some exciting news: NNZ-2566, a molecule developed as part of a collaboration between her lab and Neuren Pharma, was recently approved by the FDA, which has granted orphan drug designation to NNZ-2566 for treatment of Fragile X Syndrome. This tripeptide also demonstrates neuroprotective efficacy in models of traumatic brain injury such as concussion. Evidently, the U.S. Army is very interested in NNZ-2566, although not much is known about the mechanism of action of this exciting compound. What I found remarkable is that the tripeptide is orally bioavailable. The C-methyl proline residue makes this molecule considerably more stable than the corresponding non-methylated congener. The methyl group really “messes up” with the nearby amide bond, which apparently drives the logD down and improves the pharmacological profile of NNZ-2566. I have always thought that there is something special about C-methylproline…

http://www.neurenpharma.com/irm/content/nnz-2566-in-rett-syndrome.aspx?RID=330

Make sure you don’t miss out on the latest journal news by registering your details to receive the regular Organic & Biomolecular Chemistry e-alert.

Follow us on Twitter @OrgBiomolChem

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HOT Organic & Biomolecular Chemistry articles

The following Organic & Biomolecular Chemistry articles have all been recommened by the reviewers of the articles as being particularly interesting or particularly significant research. These have all been made free to access until 15th February 2015. The order they appear in the list holds no special meaning or ranking.

Cationic azacryptands as selective three-way DNA junction binding agents
Jana Novotna, Aurelien Laguerre, Anton Granzhan, Marc Pirrotta, Marie-Paule Teulade-Fichou and David Monchaud  
DOI: 10.1039/C4OB01846J, Paper

C4OB01846J GA


Efficient merging of copper and photoredox catalysis for the asymmetric cross-dehydrogenative-coupling of alkynes and tetrahydroisoquinolines
Inna Perepichka, Soumen Kundu, Zoë Hearne and Chao-Jun Li  
DOI: 10.1039/C4OB02138J, Paper

C4OB02138J GA


A peptide topological template for the dispersion of [60]fullerene in water
S. Bartocci, D. Mazzier, A. Moretto and M. Mba  
DOI: 10.1039/C4OB02102A, Communication
From themed collection Supramolecular Chemistry in Water

C4OB02102A GA


6-Substituted 1,2-benzoxathiine-2,2-dioxides are isoform-selective inhibitors of human carbonic anhydrases IX, XII and VA
Muhammet Tanc, Fabrizio Carta, Andrea Scozzafava and Claudiu T. Supuran  
DOI: 10.1039/C4OB02155J, Communication

C4OB02155J GA


Artificial metalloenzymes for the diastereoselective reduction of NAD+ to NAD2H
Tommaso Quinto, Daniel Häussinger, Valentin Köhler and Thomas R. Ward  
DOI: 10.1039/C4OB02071E, Communication
From themed collection Supramolecular Chemistry in Water

C4OB02071E GA

 


Design and synthesis of fluorescent 7-deazaadenosine nucleosides containing π-extended diarylacetylene motifs
Sara De Ornellas, John M. Slattery, Robert M. Edkins, Andrew Beeby, Christoph G. Baumann and Ian J. S. Fairlamb  
DOI: 10.1039/C4OB02081B, Communication

C4OB02081B GA


One-pot quadruple/triple reaction sequence: a useful tool for the synthesis of natural products
K. Kashinath and D. Srinivasa Reddy  
DOI: 10.1039/C4OB02143F, Perspective

C4OB02143F GA


 

Indole-based novel small molecules for the modulation of bacterial signalling pathways
Nripendra Nath Biswas, Samuel K. Kutty, Nicolas Barraud, George M. Iskander, Renate Griffith, Scott A. Rice, Mark Willcox, David StC. Black and Naresh Kumar  
DOI: 10.1039/C4OB02096K, Paper

C4OB02096K GA


Carbocycles from donor–acceptor cyclopropanes
Huck K. Grover, Michael R. Emmett and Michael A. Kerr  
DOI: 10.1039/C4OB02117G, Review Article

C4OB02117G GA


Synthesis of isoxazolidine-containing uridine derivatives as caprazamycin analogues
Mayumi Yamaguchi, Akira Matsuda and Satoshi Ichikawa  
DOI: 10.1039/C4OB02142H, Paper

C4OB02142H GA


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What are your colleagues reading in Organic & Biomolecular Chemistry?

The articles below are the most read Organic & Biomolecular Chemistry articles in July, August and September 2014.

Marine natural products-inspired phenylmethylene hydantoins with potent in vitro and in vivo antitumor activities via suppression of Brk and FAK signaling
Asmaa A. Sallam, Mohamed M. Mohyeldin, Ahmed I. Foudah, Mohamed R. Akl, Sami Nazzal, Sharon A. Meyer, Yong-Yu Liu and Khalid A. El Sayed 
DOI: 10.1039/C4OB00553H

Watsonianone A–C, anti-plasmodial β-triketones from the Australian tree, Corymbia watsoniana
Anthony R. Carroll, Vicky M. Avery, Sandra Duffy, Paul I. Forster and Gordon P. Guymer 
DOI: 10.1039/C2OB26931G

Pyridostatin analogues promote telomere dysfunction and long-term growth inhibition in human cancer cells
Sebastian Müller, Deborah A. Sanders, Marco Di Antonio, Stephanos Matsis, Jean-François Riou, Raphaël Rodriguez and Shankar Balasubramanian 
DOI: 10.1039/C2OB25830G

Synthesis, characterization and biological evaluation of carboranylmethylbenzo[b]acridones as novel agents for boron neutron capture therapy
A. Filipa F. da Silva, Raquel S. G. R. Seixas, Artur M. S. Silva, Joana Coimbra, Ana C. Fernandes, Joana P. Santos, António Matos, José Rino, Isabel Santos and Fernanda Marques 
DOI: 10.1039/C4OB00644E

Organic synthetic transformations using organic dyes as photoredox catalysts
Shunichi Fukuzumi and Kei Ohkubo 
DOI: 10.1039/C4OB00843J

Copper-catalysed direct radical alkenylation of alkyl bromides
Xu Zhang, Hong Yi, Zhixiong Liao, Guoting Zhang, Chao Fan, Chu Qin, Jie Liu and Aiwen Lei 
DOI: 10.1039/C4OB00813H

Metal-free oxidative olefination of primary amines with benzylic C–H bonds through direct deamination and C–H bond activation
Liang Gong, Li-Juan Xing, Tong Xu, Xue-Ping Zhu, Wen Zhou, Ning Kang and Bin Wang 
DOI: 10.1039/C4OB01025F

Recent advances in trifluoromethylation of organic compounds using Umemoto’s reagents
Cai Zhang 
DOI: 10.1039/C4OB00671B

An efficient route to synthesize isatins by metal-free, iodine-catalyzed sequential C(sp3)–H oxidation and intramolecular C–N bond formation of 2′-aminoacetophenones
Venkatachalam Rajeshkumar, Selvaraj Chandrasekar and Govindasamy Sekar 
DOI: 10.1039/C4OB01564A

Amino acid chirons: a tool for asymmetric synthesis of heterocycles
Priyanka Singh, Krishnananda Samanta, Sanjit Kumar Das and Gautam Panda 
DOI: 10.1039/C4OB00943F

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HOT Organic & Biomolecular Chemistry articles

The following Organic & Biomolecular Chemistry articles have all been recommened by the reviewers of the articles as being particularly interesting or particularly significant research. These have all been made free to access until 31st December 2014. The order they appear in the list holds no special meaning or ranking.

Catalytic asymmetric desymmetrization approaches to enantioenriched cyclopentanes
Madhu Sudan Manna and Santanu Mukherjee  
DOI: 10.1039/C4OB01649A, Perspective

C4OB01649A GA


Corrin-based chemosensors for the ASSURED detection of endogenous cyanide
Felix Zelder and Lucas Tivana  
DOI: 10.1039/C4OB01889C, Perspective


An efficient synthetic route to 1,3-bis(arylethynyl)isobenzofuran using alkoxybenzocyclobutenone as a reactive platform
Kenta Asahina, Suguru Matsuoka, Ryosuke Nakayama and Toshiyuki Hamura  
DOI: 10.1039/C4OB02012J, Communication

C4OB02012J GA


Cationic azacryptands as selective three-way DNA junction binding agents
Jana Novotna, Aurelien Laguerre, Anton Granzhan, Marc Pirrotta, Marie-Paule Teulade-Fichou and David Monchaud  
DOI: 10.1039/C4OB01846J, Paper

C4OB01846J GA


An efficient reagent for covalent introduction of alkynes into proteins
Jie Zhang, Dejun Ma, Dawei Du, Zhen Xi and Long Yi  
DOI: 10.1039/C4OB01873G, Communication

C4OB01873G GA


Efficient merging of copper and photoredox catalysis for the asymmetric cross-dehydrogenative-coupling of alkynes and tetrahydroisoquinolines
Inna Perepichka, Soumen Kundu, Zoë Hearne and Chao-Jun Li  
DOI: 10.1039/C4OB02138J, Paper

C4OB02138J GA


Naphthalene diimides as red fluorescent pH sensors for functional cell imaging
Filippo Doria, Marco Folini, Vincenzo Grande, Graziella Cimino-Reale, Nadia Zaffaroni and Mauro Freccero  
DOI: 10.1039/C4OB02054E, Paper

C4OB02054E GA

A peptide topological template for the dispersion of [60]fullerene in water
S. Bartocci, D. Mazzier, A. Moretto and M. Mba  
DOI: 10.1039/C4OB02102A, Communication
C4OB02102A GA

6-Substituted 1,2-benzoxathiine-2,2-dioxides are isoform-selective inhibitors of human carbonic anhydrases IX, XII and VA
Muhammet Tanc, Fabrizio Carta, Andrea Scozzafava and Claudiu T. Supuran  
DOI: 10.1039/C4OB02155J, Communication
C4OB02155J GA

The rapid synthesis of oxazolines and their heterogeneous oxidation to oxazoles under flow conditions
Steffen Glöckner, Duc N. Tran, Richard J. Ingham, Sabine Fenner, Zoe E. Wilson, Claudio Battilocchio and Steven V. Ley  
DOI: 10.1039/C4OB02105C, Paper
From themed collection Recent Advances in Flow Synthesis and Continuous Processing
C4OB02105C GA
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Winners at the 2014 RSC Organic Division Poster Symposium

Congratulations to the winners at the 2014 RSC Organic Division Poster Symposium, held on 01 December 2014 at the Royal Society of Chemistry, Burlington House, London.

The symposium, supported by headline sponsor F. Hoffmann-La Roche Ltd, provided a fantastic opportunity for final year organic chemistry PhD students to showcase their research and network with their peers, leading academics, and industrial chemists.

Organic & Biomolecular Chemistry was delighted to offer a front cover artwork opportunity to the winner of the First Prize, as well as a 1-year personal subscription to the journal to the winner of the Industry Prize.

First Prize

Sonja Kuschel, University of Manchester (Supervisor: Professor David Leigh). Poster title: Towards man-made ribosomes: Nanomachines for sequential peptide synthesis

Runners Up Prizes

Antony Burton, University of Bristol (Supervisor: Professor Derek Woolfson). Poster title: Installing Catalytic Activity into a de novo Designed Protein Structure

Sarah Walker, Heriot-Watt University (Supervisor: Dr Ai-Lan Lee). Poster title: Development of Pd(II)-catalysed oxidative Heck reactions and CH functionalisations

Industry Prize (selected by the industrial delegates)

Antoine Maruani, University College London (Supervisors: Professor Stephen Caddick and Dr Vijay Chudasama). Poster title: A Novel Class of Tuneable reagents for Selective Dual Modification of Proteins

Participants’ Prize (selected by the students)

Owen Davis, Imperial College London (Supervisor: Dr James Bull). Poster title: Synthesis and Functionalisation of Highly Substituted Oxetanes: Molecular Scaffolds for Drug Discovery

The event was also supported by: AstraZeneca, Evotec, Johnson Matthey Catalysis and Chiral Technologies, Pfizer Neusentis, Takeda, UCB and Vertex Pharmaceuticals.

Winners (left to right): Sonja Kuschel, Owen Davis, Sarah Walker, Antony Burton, Antoine Maruani (© MPP Image Creation / Royal Society of Chemistry)

With the judges and organising committee (left to right): Dr Andrew Thomas, Dr Anne Horan, Professor Jonathan Clayden, Mr Owen Davis, Professor Rob Field, Mrs Sonja Kuschel, Professor Julian Blagg, Miss Sarah Walker, Professor Stuart Conway, Mr Antony Burton, Mr Antoine Maruani, Dr David Rees, Dr Sarah Rook, Professor Sue Gibson, Miss Charlotte Still (© MPP Image Creation / Royal Society of Chemistry)

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