Organic & Biomolecular Chemistry Blog

Curious about which articles published in 2012 gathered most readership? Here are the Top 10 works your colleagues have been accessing in Organic & Biomolecular Chemistry:

A one-pot catalysis: the strategic classification with some recent examples
Nitin T. Patil, Valmik S. Shinde and Balakrishna Gajula
Org. Biomol. Chem., 2012, 10, 211-224
DOI: 10.1039/C1OB06432K

A convenient and mild chromatography-free method for the purification of the products of Wittig and Appel reactions
Peter A. Byrne, Kamalraj V. Rajendran, Jimmy Muldoon and Declan G. Gilheany
Org. Biomol. Chem., 2012, 10, 3531-3537
DOI: 10.1039/C2OB07074J

Imidazole derivatives: A comprehensive survey of their recognition properties
Pedro Molina, Alberto Tárraga and Francisco Otón
Org. Biomol. Chem., 2012, 10, 1711-1724
DOI: 10.1039/C2OB06808G

Enhanced reduction of C–N multiple bonds using sodium borohydride and an amorphous nickel catalyst
Shouxin Liu, Yihua Yang, Xiaoli Zhen, Junzhang Li, Huimin He, Juan Feng and Andrew Whiting
Org. Biomol. Chem., 2012, 10, 663-670
DOI: 10.1039/C1OB06471A

Strategies for the enantioselective synthesis of spirooxindoles
Nicolas R. Ball-Jones, Joseph J. Badillo and Annaliese K. Franz
Org. Biomol. Chem., 2012, 10, 5165-5181
DOI: 10.1039/C2OB25184A

Thiol–yne coupling: revisiting old concepts as a breakthrough for up-to-date applications
Alessandro Massi and Daniele Nanni
Org. Biomol. Chem., 2012, 10, 3791-3807
DOI: 10.1039/C2OB25217A

Small molecule control of bacterial biofilms
Roberta J. Worthington, Justin J. Richards and Christian Melander
Org. Biomol. Chem., 2012, 10, 7457-7474
DOI: 10.1039/C2OB25835H

Asymmetric organocatalytic formation of protected and unprotected tetroses under potentially prebiotic conditions
Laurence Burroughs, Paul A. Clarke, Henrietta Forintos, James A. R. Gilks, Christopher J. Hayes, Matthew E. Vale, William Wade and Myriam Zbytniewski
Org. Biomol. Chem., 2012, 10, 1565-1570
DOI: 10.1039/C1OB06798B

Olefin cross-metathesis for the synthesis of heteroaromatic compounds
Timothy J. Donohoe, John F. Bower and Louis K. M. Chan
Org. Biomol. Chem., 2012, 10, 1322-1328
DOI: 10.1039/C2OB06659A

Selective N-alkylation of amines using nitriles under hydrogenation conditions: facile synthesis of secondary and tertiary amines
Takashi Ikawa, Yuki Fujita, Tomoteru Mizusaki, Sae Betsuin, Haruki Takamatsu, Tomohiro Maegawa, Yasunari Monguchi and Hironao Sajiki
Org. Biomol. Chem., 2012, 10, 293-304
DOI: 10.1039/C1OB06303K

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This month sees the following articles in Organic & Biomolecular Chemistry that are in the top ten most accessed:

Recent progress of core-substituted naphthalenediimides: highlights from 2010  
Sheshanath V. Bhosale, Sidhanath V. Bhosale and Suresh K. Bhargava  
Org. Biomol. Chem., 2012, 10, 6455-6468
DOI: 10.1039/C2OB25798J

A new N-imidazolyl-1,8-naphthalimide based fluorescence sensor for fluoride detection  
Junqi Wang, Lingyun Yang, Chen Hou and Haishi Cao  
Org. Biomol. Chem., 2012, 10, 6271-6274
DOI: 10.1039/C2OB25903F

Asymmetric organocatalytic diboration of alkenes  
Amadeu Bonet, Cristina Sole, Henrik Gulyás and Elena Fernández  
Org. Biomol. Chem., 2012, 10, 6621-6623
DOI: 10.1039/C2OB26079D

Transition metal-catalyzed fluorination of multi carbon–carbon bonds: new strategies for fluorinated heterocycles 
Guosheng Liu  
Org. Biomol. Chem., 2012, 10, 6243-6248
DOI: 10.1039/C2OB25702E

π-Fused bis-BODIPY as a candidate for NIR dyes  
Mitsunori Nakamura, Hiroyuki Tahara, Kohtaro Takahashi, Toshi Nagata, Hiroki Uoyama, Daiki Kuzuhara, Shigeki Mori, Tetsuo Okujima, Hiroko Yamada and Hidemitsu Uno  
Org. Biomol. Chem., 2012, 10, 6840-6849
DOI: 10.1039/C2OB25930C
 
Enantio- and diastereocontrolled conversion of chiral epoxides to trans-cyclopropane carboxylates: application to the synthesis of cascarillic acid, grenadamide and L-(−)-CCG-II  
Pradeep Kumar, Abhishek Dubey and Anand Harbindu  
Org. Biomol. Chem., 2012, 10, 6987-6994
DOI: 10.1039/C2OB25622C  
 
From biomass to medicines. A simple synthesis of indolo[3,2-c]quinolines, antimalarial alkaloid isocryptolepine, and its derivatives 
Maxim G. Uchuskin, Arkady S. Pilipenko, Olga V. Serdyuk, Igor V. Trushkov and Alexander V. Butin  
Org. Biomol. Chem., 2012, 10, 7262-7265
DOI: 10.1039/C2OB25836F  

Chiral phosphine-catalyzed asymmetric allylic alkylation of 3-substituted benzofuran-2(3H)-ones or oxindoles with Morita–Baylis–Hillman carbonates  
De Wang, Yuan-Liang Yang, Jia-Jun Jiang and Min Shi  
Org. Biomol. Chem., 2012, 10, 7158-7166
DOI: 10.1039/C2OB25694K  
 
Diverted organic synthesis (DOS): accessing a new, natural product inspired, neurotrophically active scaffold through an intramolecular Pauson–Khand reaction  
Goverdhan Mehta, Ramesh Samineni, Pabbaraja Srihari, R. Gajendra Reddy and Sumana Chakravarty  
Org. Biomol. Chem., 2012, 10, 6830-6833
DOI: 10.1039/C2OB26107C  
 
Asymmetric synthesis of (+)-vertine and (+)-lythrine 
Laëtitia Chausset-Boissarie, Roman Àrvai, Graham R. Cumming, Laure Guénée and E. Peter Kündig 
Org. Biomol. Chem., 2012, 10, 6473-6479
DOI: 10.1039/C2OB25880C  

Why not take a look at the articles today and blog your thoughts and comments below.

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This month sees the following articles in Organic & Biomolecular Chemistry that are in the top ten most accessed:

Efficient iodine catalyzed three components domino reaction for the synthesis of 1-((phenylthio)(phenyl)methyl)pyrrolidin-2-one derivatives possessing anticancer activities
Gunasekar Ramachandran, Natesan S. Karthikeyan, Periyasamy Giridharan and Kulathu I. Sathiyanarayanan
Org. Biomol. Chem., 2012, 10, 5343-5346
DOI: 10.1039/C2OB25530H

A BODIPY-based colorimetric and fluorometric chemosensor for Hg(II) ions and its application to living cell imaging
Mani Vedamalai and Shu-Pao Wu
Org. Biomol. Chem., 2012, 10, 5410-5416
DOI: 10.1039/C2OB25589H

Copper-catalyzed domino coupling reaction: an efficient method to synthesize oxindoles
Jen-Chieh Hsieh, An-Yi Cheng, Jun-Hao Fu and Ting-Wei Kang
Org. Biomol. Chem., 2012, 10, 6404-6409
DOI: 10.1039/C2OB26110C

Asymmetric formal synthesis of schulzeines A and C
Jaebong Jang, Jong-Wha Jung, Jaeseung Ahn, Jaehoon Sim, Dong-Jo Chang, Dae-Duk Kim and Young-Ger Suh
Org. Biomol. Chem., 2012, 10, 5202-5204
DOI: 10.1039/C2OB25772F

Chiral quaternary phosphonium salts: a new class of organocatalysts
Dieter Enders and Thanh Vinh Nguyen
Org. Biomol. Chem., 2012, 10, 5327-5331
DOI: 10.1039/C2OB25823D

Total synthesis of indole-3-acetonitrile-4-methoxy-2-C-β-D-glucopyranoside. Proposal for structural revision of the natural product
Akop Yepremyan and Thomas G. Minehan
Org. Biomol. Chem., 2012, 10, 5194-5196
DOI: 10.1039/C2OB25821H

Enantioselective synthesis of 3,3′-dihydropyrryl-spirooxindoles via an organocatalytic three-component reaction
Wen-Tao Wei, Chun-Xia Chen, Rui-Jiong Lu, Jin-Jia Wang, Xue-Jing Zhang and Ming Yan
Org. Biomol. Chem., 2012, 10, 5245-5252
DOI: 10.1039/C2OB25629K

A convergent stereocontrolled total synthesis of (–)-terpestacin
Yehua Jin and Fayang G. Qiu
Org. Biomol. Chem., 2012, 10, 5452-5455
DOI: 10.1039/C2OB25940K

A cyanine based fluorophore emitting both single photon near-infrared fluorescence and two-photon deep red fluorescence in aqueous solution
Lu Wang, Jiefu Jin, Xishan Chen, Hai-Hua Fan, Billy King Fai Li, Kok-Wai Cheah, Ning Ding, Shenghong Ju, Wing-Tak Wong and Cong Li
Org. Biomol. Chem., 2012, 10, 5366-5370
DOI: 10.1039/C2OB25619C

Transition metal-catalyzed fluorination of multi carbon–carbon bonds: new strategies for fluorinated heterocycles
Guosheng Liu
Org. Biomol. Chem., 2012, 10, 6243-6248
DOI: 10.1039/C2OB25702E

Why not take a look at the articles today and blog your thoughts and comments below.

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This month sees the following articles in Organic & Biomolecular Chemistry that are in the top ten most accessed:

PTSA-catalyzed Mannich-type–cyclization–oxidation tandem reactions: one-pot synthesis of 1,3,5-substituted pyrazoles from aldehydes, hydrazines and alkynes
Pei Liu, Ying-Ming Pan, Yan-Li Xu and Heng-Shan Wang
Org. Biomol. Chem., 2012, 10, 4696-4698
DOI: 10.1039/C2OB25487E

A new ratiometric and colorimetric chemosensor for cyanide anion based on Coumarin–hemicyanine hybrid
Zhenghao Yang, Zhipeng Liu, Yuncong Chen, Xiaoqing Wang, Weijiang He and Yi Lu
Org. Biomol. Chem., 2012, 10, 5073-5076
DOI: 10.1039/C2OB25516B

Highly enantioselective Biginelli reaction catalyzed by SPINOL-phosphoric acids
Fangxi Xu, Dan Huang, Xufeng Lin and Yanguang Wang
Org. Biomol. Chem., 2012, 10, 4467-4470
DOI: 10.1039/C2OB25663K

One-pot synthesis of 1,2,3-triazoles from boronic acids in water using Cu(II)–ß-cyclodextrin complex as a nanocatalyst
Babak Kaboudin, Yaghoub Abedi and Tsutomu Yokomatsu
Org. Biomol. Chem., 2012, 10, 4543-4548
DOI: 10.1039/C2OB25061F

The ligand and base-free Pd-catalyzed oxidative Heck reaction of arylboronic acids and olefins
Peng Sun, Yan Zhu, Hailong Yang, Hong Yan, Linhua Lu, Xiang Zhang and Jincheng Mao
Org. Biomol. Chem., 2012, 10, 4512-4515
DOI: 10.1039/C2OB25462J

Very high stereoselectivity in organocatalyzed desymmetrizing aldol reactions of 3-substituted cyclobutanones
David J. Aitken, Angela M. Bernard, Francesca Capitta, Angelo Frongia, Régis Guillot, Jean Ollivier, Pier Paolo Piras, Francesco Secci and Marco Spiga
Org. Biomol. Chem., 2012, 10, 5045-5048
DOI: 10.1039/C2OB25813G

First total synthesis of (+)-indicanone
Yujiro Hayashi, Kumiko Ogawa, Fuyuhiko Inagaki and Chisato Mukai
Org. Biomol. Chem., 2012, 10, 4747-4751
DOI: 10.1039/C2OB25500F

Strategy for catch and release of azide-tagged biomolecules utilizing a photolabile strained alkyne construct
Martin Golkowski, Carlo Pergola, Oliver Werz and Thomas Ziegler
Org. Biomol. Chem., 2012, 10, 4496-4499
DOI: 10.1039/C2OB25440A

Synthesis of diversely 1,3,5-trisubstituted pyrazoles via 5-exo-dig cyclization
Dmitry A. Borkin, Mirela Puscau, Alena Carlson, Agnes Solan, Kraig A. Wheeler, Béla Török and Roman Dembinski
Org. Biomol. Chem., 2012, 10, 4505-4508
DOI: 10.1039/C2OB25580D

Thiol–yne coupling: revisiting old concepts as a breakthrough for up-to-date applications
Alessandro Massi and Daniele Nanni
Org. Biomol. Chem., 2012, 10, 3791-3807
DOI: 10.1039/C2OB25217A

Why not take a look at the articles today and blog your thoughts and comments below.

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This month sees the following articles in Organic & Biomolecular Chemistry that are in the top ten most accessed:

Synthesis of the anti-influenza agent (-)-oseltamivir free base and (-)-methyl 3-epi-shikimate
Varun Rawat, Soumen Dey and Arumugam Sudalai
Org. Biomol. Chem., 2012, 10, 3988-3990
DOI: 10.1039/C2OB25635E

Thiol–yne coupling: revisiting old concepts as a breakthrough for up-to-date applications
Alessandro Massi and Daniele Nanni
Org. Biomol. Chem., 2012, 10, 3791-3807
DOI: 10.1039/C2OB25217A

Cu(I)-catalyzed annulation for the synthesis of substituted naphthalenes using o-bromobenzaldehydes and ß-ketoesters as substrates
Chandi C. Malakar, Kavitha Sudheendran, Hans-Georg Imrich, Sabine Mika and Uwe Beifuss
Org. Biomol. Chem., 2012, 10, 3899-3905
DOI: 10.1039/C2OB06963F

A convenient and mild chromatography-free method for the purification of the products of Wittig and Appel reactions
Peter A. Byrne, Kamalraj V. Rajendran, Jimmy Muldoon and Declan G. Gilheany
Org. Biomol. Chem., 2012, 10, 3531-3537
DOI: 10.1039/C2OB07074J

Copper(II)-mediated oxidative cyclization of enamides to oxazoles
Alison E. Wendlandt and Shannon S. Stahl
Org. Biomol. Chem., 2012, 10, 3866-3870
DOI: 10.1039/C2OB25310K

Synthesis of carbazolones and 3-acetylindoles via oxidative C–N bond formation through PIFA-mediated annulation of 2-aryl enaminones
Xu Ban, Yan Pan, Yingfu Lin, Songqing Wang, Yunfei Du and Kang Zhao
Org. Biomol. Chem., 2012, 10, 3606-3609
DOI: 10.1039/C2OB25348H

Water soluble extended naphthalene diimides as pH fluorescent sensors and G-quadruplex ligands
Filippo Doria, Matteo Nadai, Giovanna Sattin, Luca Pasotti, Sara N. Richter and Mauro Freccero
Org. Biomol. Chem., 2012, 10, 3830-3840
DOI: 10.1039/C2OB07006E

Tunnelling control of chemical reactions – the organic chemist’s perspective
David Ley, Dennis Gerbig and Peter R. Schreiner
Org. Biomol. Chem., 2012, 10, 3781-3790
DOI: 10.1039/C2OB07170C

Enantioselective synthesis of bio-relevant 3,5-diaryl pyrazolines
Olivier Mahé, Isabelle Dez, Vincent Levacher and Jean-François Brière
Org. Biomol. Chem., 2012, 10, 3946-3954
DOI: 10.1039/C2OB25227A

Development of strong Brønsted base catalysis: catalytic direct-type Mannich reactions of non-activated esters via a product-base mechanism
Yasuhiro Yamashita, Hirotsugu Suzuki and Shū Kobayashi
Org. Biomol. Chem., 2012, Advance Article
DOI: 10.1039/C2OB25522G

Why not take a look at the articles today and blog your thoughts and comments below.

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This month sees the following articles in Organic & Biomolecular Chemistry that are in the top ten most accessed:

Bioinspired organocatalytic asymmetric reactions
Luca Bernardi, Mariafrancesca Fochi, Mauro Comes Franchini and Alfredo Ricci
Org. Biomol. Chem., 2012, 10, 2911-2922
DOI: 10.1039/C2OB07037E

A convenient approach to ß-heteroarylated (C–N bond) ketones from Cs₂CO₃ promoted reaction between propargyl alcohols and nitrogen-heterocycles
M. Bhanuchandra, Malleswara Rao Kuram and Akhila K. Sahoo
Org. Biomol. Chem., 2012, 10, 3538-3555
DOI: 10.1039/C2OB25165E

A seminaphthofluorescein-based fluorescent chemodosimeter for the highly selective detection of cysteine
Xiaofeng Yang, Yixing Guo and Robert M. Strongin
Org. Biomol. Chem., 2012, 10, 2739-2741
DOI: 10.1039/C2OB25178G

On a so-called “kinetic anomeric effect” in chemical glycosylation
Ian Cumpstey
Org. Biomol. Chem., 2012, 10, 2503-2508
DOI: 10.1039/C2OB06696C

A catalytic metal-free Ritter reaction to 3-substituted 3-aminooxindoles
Feng Zhou, Miao Ding and Jian Zhou
Org. Biomol. Chem., 2012, 10, 3178-3181
DOI: 10.1039/C2OB25319D

A highly enantioselective approach towards 2-substituted 3-bromopyrrolidines
Jie Chen, Ling Zhou and Ying-Yeung Yeung
Org. Biomol. Chem., 2012, 10, 3808-3811
DOI: 10.1039/C2OB25327E

Combined coinage metal catalysis in natural product synthesis: total synthesis of (+)-varitriol and seven analogs
Tao Sun, Carl Deutsch and Norbert Krause
Org. Biomol. Chem., 2012, Advance Article
DOI: 10.1039/C2OB25069A

Enantioselective synthesis of 2,5-dihydrobenzo[b]azepine derivatives via iridium-catalyzed asymmetric allylic amination with 2-allylanilines and ring-closing-metathesis reaction
Ke-Yin Ye, Li-Xin Dai and Shu-Li You
Org. Biomol. Chem., 2012, Advance Article
DOI: 10.1039/C2OB00036A

Silver-promoted Friedel–Crafts reaction: concise total synthesis of (-)-ardeemin, (-)-acetylardeemin and (-)-formylardeemin
Y. Wang, C. Kong, Y. Du, H. Song, D. Zhang and Y. Qin
Org. Biomol. Chem., 2012, 10, 2793-2797
DOI: 10.1039/C2OB00014H

Highly efficient asymmetric anti-Mannich reactions of carbonyl compounds with N-carbamoyl imines catalyzed by amino-thiourea organocatalysts
Jiuzhi Gao, Yongming Chuan, Jiali Li, Fang Xie and Yungui Peng
Org. Biomol. Chem., 2012, 10, 3730-3738
DOI: 10.1039/C2OB00049K

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Organic & Biomolecular Chemistry? Then why not submit to us today or alternatively email us your suggestions.

This month sees the following articles in Organic & Biomolecular Chemistry that are in the top ten most accessed:

Imidazole derivatives: A comprehensive survey of their recognition properties
Pedro Molina, Alberto Tárraga and Francisco Otón
Org. Biomol. Chem., 2012, 10, 1711-1724
DOI: 10.1039/C2OB06808G

Copper(I)–amine metallo-organocatalyzed synthesis of carbo- and heterocyclic systems
Benjamin Montaignac, Victor Östlund, Maxime R. Vitale, Virgnie Ratovelomanana-Vidal and Véronique Michelet
Org. Biomol. Chem., 2012, 10, 2300-2306
DOI: 10.1039/C2OB06449A

Asymmetric organocatalytic formation of protected and unprotected tetroses under potentially prebiotic conditions
Laurence Burroughs, Paul A. Clarke, Henrietta Forintos, James A. R. Gilks, Christopher J. Hayes, Matthew E. Vale, William Wade and Myriam Zbytniewski
Org. Biomol. Chem., 2012, 10, 1565-1570
DOI: 10.1039/C1OB06798B

Facile synthesis of 4-substituted 3,4-dihydrocoumarins via an organocatalytic double decarboxylation process
Shiyong Peng, Lei Wang, Haibing Guo, Shaofa Sun and Jian Wang
Org. Biomol. Chem., 2012, 10, 2537-2541
DOI: 10.1039/C2OB25075F

On a so-called “kinetic anomeric effect” in chemical glycosylation
Ian Cumpstey
Org. Biomol. Chem., 2012, 10, 2503-2508
DOI: 10.1039/C2OB06696C

Olefin cross-metathesis for the synthesis of heteroaromatic compounds
Timothy J. Donohoe, John F. Bower and Louis K. M. Chan
Org. Biomol. Chem., 2012, 10, 1322-1328
DOI: 10.1039/C2OB06659A

Fluorogenic sensing of CH₃CO₂^– and H₂PO₄^– by ditopic receptor through conformational change
Nisar Ahmed, Vangaru Suresh, Bahareh Shirinfar, Inacrist Geronimo, Amita Bist, In-Chul Hwang and Kwang S. Kim
Org. Biomol. Chem., 2012, 10, 2094-2100
DOI: 10.1039/C2OB06994F

A selective fluorescent turn-on NIR probe for cysteine
Xin-Dong Jiang, Jian Zhang, Xiangmin Shao and Weili Zhao
Org. Biomol. Chem., 2012, 10, 1966-1968
DOI: 10.1039/C2OB07046D

Chemical generation of o-quinone monoimines for the rapid construction of 1,4-benzoxazine derivatives
Naganjaneyulu Bodipati and Rama Krishna Peddinti
Org. Biomol. Chem., 2012, 10, 1958-1961
DOI: 10.1039/C2OB06681E

Construction of highly functional α-amino nitriles via a novel multicomponent tandem organocatalytic reaction: a facile access to a-methylene γ-lactams
Feng Pan, Jian-Ming Chen, Zhe Zhuang, Yin-Zhi Fang, Sean Xiao-An Zhang and Wei-Wei Liao
Org. Biomol. Chem., 2012, 10, 2214-2217
DOI: 10.1039/C2OB07112F

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Organic & Biomolecular Chemistry? Then why not submit to us today or alternatively email us your suggestions.

This month sees the following articles in Organic & Biomolecular Chemistry that are in the top ten most accessed:

Asymmetric organocatalytic formation of protected and unprotected tetroses under potentially prebiotic conditions
Laurence Burroughs, Paul A. Clarke, Henrietta Forintos, James A. R. Gilks, Christopher J. Hayes, Matthew E. Vale, William Wade and Myriam Zbytniewski
Org. Biomol. Chem., 2012, 10, 1565-1570
DOI: 10.1039/C1OB06798B

Total synthesis of (+)-anamarine
Krishnammagari Suresh Kumar and Cirandur Suresh Reddy
Org. Biomol. Chem., 2012, 10, 2647-2655
DOI: 10.1039/C2OB06940G

Olefin cross-metathesis for the synthesis of heteroaromatic compounds
Timothy J. Donohoe, John F. Bower and Louis K. M. Chan
Org. Biomol. Chem., 2012, 10, 1322-1328
DOI: 10.1039/C2OB06659A

Highly selective, naked-eye and fluorescent “off-on” probe for detection of histidine/histidine-rich proteins and its application in living cell imaging
Shenyi Zhang, Chunmei Yang, Weiping Zhu, Bubing Zeng, Youjun Yang, Yufang Xu and Xuhong Qian
Org. Biomol. Chem., 2012, 10, 1653-1658
DOI: 10.1039/C2OB06520G

Direct C–H cross-coupling approach to heteroaryl coumarins
Minsik Min, Bomi Kim and Sungwoo Hong
Org. Biomol. Chem., 2012, Advance Article
DOI: 10.1039/C2OB07137A

Bioinspired organocatalytic asymmetric reactions
Luca Bernardi, Mariafrancesca Fochi, Mauro Comes Franchini and Alfredo Ricci
Org. Biomol. Chem., 2012, Advance Article
DOI: 10.1039/C2OB07037E

Imidazole derivatives: A comprehensive survey of their recognition properties
Pedro Molina, Alberto Tárraga and Francisco Otón
Org. Biomol. Chem., 2012, 10, 1711-1724
DOI: 10.1039/C2OB06808G

An iterative Shimizu non-aldol approach for the stereoselective synthesis of C13-C22 fragment of callystatin A
Sandip A. Pujari and Krishna P. Kaliappan
Org. Biomol. Chem., 2012, 10, 1750-1753
DOI: 10.1039/C2OB06838A

Organocatalytic stereoselective synthesis of passifloricin A
Pradeep Kumar, Menaka Pandey, Priti Gupta and Dilip D. Dhavale
Org. Biomol. Chem., 2012, 10, 1820-1825
DOI: 10.1039/C2OB06711K

Direct preparation of thiazoles, imidazoles, imidazopyridines and thiazolidines from alkenes
Timothy J. Donohoe, Mikhail A Kabeshov, Akshat H. Rathi and Ian E. D. Smith
Org. Biomol. Chem., 2012, 10, 1093-1101
DOI: 10.1039/C1OB06587D

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Organic & Biomolecular Chemistry? Then why not submit to us today or alternatively email us your suggestions.

This month sees the following articles in Organic & Biomolecular Chemistry that are in the top ten most accessed:

Is nevirapine atropisomeric? Experimental and computational evidence for rapid conformational inversion
Edmund W. D. Burke, Gareth A. Morris, Mark A. Vincent, Ian H. Hillier and Jonathan Clayden
Org. Biomol. Chem., 2012, 10, 716-719
DOI: 10.1039/C1OB06490H

A one-pot catalysis: the strategic classification with some recent examples
Nitin T. Patil, Valmik S. Shinde and Balakrishna Gajula
Org. Biomol. Chem., 2012, 10, 211-224
DOI: 10.1039/C1OB06432K

N-Heterocyclic carbene catalysed aerobic oxidation of aromatic aldehydes to aryl esters using boronic acids
Panjab Arde, B. T. Ramanjaneyulu, Virsinha Reddy, Apurv Saxena and R. Vijaya Anand
Org. Biomol. Chem., 2012, 10, 848-851
DOI: 10.1039/C1OB06566A

Direct preparation of thiazoles, imidazoles, imidazopyridines and thiazolidines from alkenes
Timothy J. Donohoe, Mikhail A Kabeshov, Akshat H. Rathi and Ian E. D. Smith
Org. Biomol. Chem., 2012, 10, 1093-1101
DOI: 10.1039/C1OB06587D

Towards the systematic exploration of chemical space
Mark Dow, Martin Fisher, Thomas James, Francesco Marchetti and Adam Nelson
Org. Biomol. Chem., 2012, Advance Article
DOI: 10.1039/C1OB06098H

Fluoride-selective optical sensor based on the dipyrrolyl-tetrathiafulvalene chromophore
Shadi Rivadehi, Ellen F. Reid, Conor F. Hogan, Sheshanath V. Bhosale and Steven J. Langford
Org. Biomol. Chem., 2012, 10, 705-709
DOI: 10.1039/C1OB06459B

Syntheses of furo[3,4-c]coumarins and related furyl coumarin derivatives via intramolecular Wittig reactions
Yeong-Jiunn Jang,  Siang-en Syu,  Yu-Jhang Chen,  Mei-Chun Yang and Wenwei Lin
Org. Biomol. Chem., 2012, 10, 843-847
DOI: 10.1039/C1OB06571H

Synthesis and biological activity of phosphonoacetate- and thiophosphonoacetate-modified 2′-O-methyl oligoribonucleotides
Richard N. Threlfall, Adrian G. Torres, Angelika Krivenko, Michael J. Gait and Marvin H. Caruthers
Org. Biomol. Chem., 2012, 10, 746-754
DOI: 10.1039/C1OB06614E

C–H functionalization of tertiary amines by cross dehydrogenative coupling reactions: solvent-free synthesis of α-aminonitriles and ß-nitroamines under aerobic condition
Kaliyamoorthy Alagiri and Kandikere Ramaiah Prabhu
Org. Biomol. Chem., 2012, 10, 835-842
DOI: 10.1039/C1OB06466E

Calixarene-induced aggregation of perylene bisimides
Dong-Sheng Guo,  Bang-Ping Jiang,  Xiang Wang and Yu Liu
Org. Biomol. Chem., 2012, 10, 720-723
DOI: 10.1039/C2OB06973C

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This month sees the following articles in Organic & Biomolecular Chemistry that are in the top ten most accessed:

Preparation and reactivity of imino glycals: stereocontrolled, divergent approach to imino sugars
Paul J. Dransfield, Paul M. Gore, Ivan Prokeš, Michael Shipman and Alexandra M. Z. Slawin
Org. Biomol. Chem., 2003, 1, 2723-2733
DOI: 10.1039/B303817C

A one-pot catalysis: the strategic classification with some recent examples
Nitin T. Patil, Valmik S. Shinde and Balakrishna Gajula
Org. Biomol. Chem., 2012, 10, 211-224
DOI: 10.1039/C1OB06432K

An organocatalytic approach to enantiomerically enriched α-arylcyclohexenones and cyclohexanones
Sara Duce, María Jorge, Inés Alonso, José Luis García Ruano and M. Belén Cid
Org. Biomol. Chem., 2011, 9, 8253-8260
DOI: 10.1039/C1OB06356A

Synthesis of oxindoles via visible light photoredox catalysis
Xuhui Ju, Yan Liang, Pingjing Jia, Weifei Li and Wei Yu
Org. Biomol. Chem., 2012, 10, 498-501
DOI: 10.1039/C1OB06652H

Squaramide-catalyzed enantioselective Michael addition of malononitrile to chalcones
Wen Yang, Yang Jia and Da-Ming Du
Org. Biomol. Chem., 2012, 10, 332-338
DOI: 10.1039/C1OB06302B

Organocatalytic asymmetric tandem condensation–intramolecular rearrangement–protonation: an approach to optically active α-amino thioester derivatives
Francesca Capitta, Angelo Frongia, Pier Paolo Piras, Patrizia Pitzanti and Francesco Secci
Org. Biomol. Chem., 2012, 10, 490-494
DOI: 10.1039/C1OB06623D

Oxidative Prins and Prins/Friedel–Crafts cyclizations for the stereoselective synthesis of dioxabicycles and hexahydro-1H-benzo[f]isochromenes via the benzylic C–H activation
B. V. Subba Reddy, Prashant Borkar, J. S. Yadav, P. Purushotham Reddy, A. C. Kunwar, B. Sridhar and René Grée
Org. Biomol. Chem., 2012, Advance Article
DOI: 10.1039/C1OB06489D

Gold-mediated bifunctional modification of oligosaccharides via a three-component coupling reaction
Karen Ka-Yan Kung, Gai-Li Li, Lan Zou, Hiu-Chi Chong, Yun-Chung Leung, Ka-Hing Wong, Vanessa Kar-Yan Lo, Chi-Ming Che and Man-Kin Wong
Org. Biomol. Chem., 2012, 10, 925-930
DOI: 10.1039/C1OB06429K

Asymmetric organocatalysis
Jayasree Seayad and Benjamin List
Org. Biomol. Chem., 2005, 3, 719-724
DOI: 10.1039/B415217B

Indolizinones as synthetic scaffolds: fundamental reactivity and the relay of stereochemical information
Alison R. Hardin Narayan and Richmond Sarpong
Org. Biomol. Chem., 2012, 10, 70-78
DOI: 10.1039/C1OB06423A

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