Organic & Biomolecular Chemistry Blog

This month sees the following articles in OBC that are in the top ten most accessed:-

Chiral BINOL-derived phosphoric acids: privileged Bronsted acid organocatalysts for C-C bond formation reactions 
Alexandru Zamfir, Sebastian Schenker, Matthias Freund and Svetlana B. Tsogoeva 
Org. Biomol. Chem., 2010, 8, 5262-5276, DOI: 10.1039/C0OB00209G, Perspective 

Chiral separation by enantioselective liquid-liquid extraction 
Boelo Schuur, Bastiaan J. V. Verkuijl, Adriaan J. Minnaard, Johannes G. de Vries, Hero J. Heeres and Ben L. Feringa 
Org. Biomol. Chem., 2011, 9, 36-51, DOI: 10.1039/C0OB00610F, Perspective 

Enantioselective organocatalytic domino Michael ‘acetalization’ Henry reactions of 2-hydroxynitrostyrene and aldehyde for the synthesis of tetrahydro-6H-benzo[c]chromenones 
Bor-Cherng Hong, Prakash Kotame and Ju-Hsiou Liao 
Org. Biomol. Chem., 2011, 9, 382-386, DOI: 10.1039/C0OB00834F, Communication 

Oxidative amide synthesis directly from alcohols with amines 
Cheng Chen and Soon Hyeok Hong 
Org. Biomol. Chem., 2011, 9, 20-26, DOI: 10.1039/C0OB00342E, Emerging Area 

Conformationally rigid aromatic amino acids as potential building blocks for abiotic foldamers 
Veera V. E. Ramesh, Arup Roy, Kuruppanthara N. Vijayadas, Amol M. Kendhale, Panchami Prabhakaran, Rajesh Gonnade, Vedavati G. Puranik and Gangadhar J. Sanjayan 
Org. Biomol. Chem., 2011, 9, 367-369, DOI: 10.1039/C0OB00593B, Communication 

Asymmetric Synthesis of 1-Deoxyazasugars from Chiral Aziridines 
Alok Singh, Bongchan Kim, Won Koo Lee and Hyun-Joon Ha 
Org. Biomol. Chem., 2011, Advance Article, DOI: 10.1039/C0OB00730G, Paper 

Naturally occurring circular proteins: distribution, biosynthesis and evolution 
Laura Cascales and David J Craik 
Org. Biomol. Chem., 2010, 8, 5035-5047, DOI: 10.1039/C0OB00139B, Perspective 

Highly sensitive and selective colorimetric and off-on fluorescent probe for Cu2+ based on rhodamine derivative 
Chunwei Yu, Jun Zhang, Rui Wang and Lingxin Chen 
Org. Biomol. Chem., 2010, 8, 5277-5279, DOI: 10.1039/C0OB00553C, Communication 

New Fluorescent trans-DihydroFluoren-3-ones from Aldol – Robinson Annulation – Regioselective Addition Involved One-Pot Reaction 
Yingpeng Huo, Xu Qiu, Weiyan Shao, Jianing Huang, Yanjun Yu, Yinglin Zuo, Linkun An, Jun Du and Xianzhang Bu 
Org. Biomol. Chem., 2010, 8, 5048-5052, DOI: 10.1039/C0OB00401D, Communication 

Chiral Brønsted Acid Catalyzed Asymmetric Friedel-Crafts Alkylation Reaction of Indoles with a,b-Unsaturated Ketones: Short Access to Optically Active 2- and 3-Substituted Indole 
Tsubasa Sakamoto, Junji Itoh, Keiji Mori and Takahiko Akiyama 
Org. Biomol. Chem., 2010, 8, 5448-5454, DOI: 10.1039/C0OB00197J, Paper 

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to OBC? Then why not submit to us today or alternatively email us your suggestions.
 

This month sees the following articles in OBC that are in the top ten most accessed:-

Regioselective Syntheses of Fully-Substituted 1,2,3-Triazoles: The CuAAC/C–H Bond Functionalization Nexus 
Lutz Ackermann and Harish Kumar Potukuchi 
Org. Biomol. Chem., 2010, 8, 4503-4513, DOI: 10.1039/C0OB00212G, Perspective 

Practical access to highly enantioenriched quaternary carbon Michael adducts using simple organocatalysts 
Thomas C. Nugent, Mohammad Shoaib and Amna Shoaib 
Org. Biomol. Chem., 2011, Advance Article, DOI: 10.1039/C0OB00822B, Communication  

Microwave and flow syntheses of Pseudomonas quinolone signal (PQS) and analogues 
James T. Hodgkinson, Warren R. J. D. Galloway, Shreya Saraf, Ian R. Baxendale, Steven V. Ley, Mark Ladlow, Martin Welch and David R. Spring 
Org. Biomol. Chem., 2011, Advance Article, DOI: 10.1039/C0OB00652A, Communication  

Discovery of a quorum sensing modulator pharmacophore by 3D small-molecule microarray screening 
David M. Marsden, Rebecca L. Nicholson, Mette E. Skindersoe, Warren R. J. D. Galloway, Hannah F. Sore, Michael Givskov, George P. C. Salmond, Mark Ladlow, Martin Welch and David R. Spring 
Org. Biomol. Chem., 2010, 8, 5313-5323, DOI: 10.1039/C0OB00300J, Paper 

Efficient conversion of triacylglycerols and fatty acids to biodiesel in a microwave reactor using metal triflate catalysts 
Aaron M. Socha and Jason K. Sello 
Org. Biomol. Chem., 2010, 8, 4753-4756, DOI: 10.1039/C0OB00014K, Paper  

A new building block for anion supramolecular chemistry. Study of carbazolocarbazole as anion receptor 
David Curiel, Miriam Más-Montoya, Guzmán Sánchez, Raúl A. Orenes, Pedro Molina and Alberto Tárraga 
Org. Biomol. Chem., 2010, 8, 4811-4814, DOI: 10.1039/C0OB00522C, Communication  

Rational design of visible and NIR distyryl-BODIPY dyes from a novel fluorinated platform 
Olivier Galangau, Cécile Dumas-Verdes, Rachel Méallet-Renault and Gilles Clavier 
Org. Biomol. Chem., 2010, 8, 4546-4553, DOI: 10.1039/C004812G, Paper  

Highly sensitive and selective colorimetric and off-on fluorescent probe for Cu2+ based on rhodamine derivative 
Chunwei Yu, Jun Zhang, Rui Wang and Lingxin Chen 
Org. Biomol. Chem., 2010, 8, 5277-5279, DOI: 10.1039/C0OB00553C, Communication  

Chiral Brønsted Acid Catalyzed Asymmetric Friedel-Crafts Alkylation Reaction of Indoles with a,b-Unsaturated Ketones: Short Access to Optically Active 2- and 3-Substituted Indole 
Tsubasa Sakamoto, Junji Itoh, Keiji Mori and Takahiko Akiyama 
Org. Biomol. Chem., 2010, 8, 5448-5454, DOI: 10.1039/C0OB00197J, Paper 

Design, synthesis and biological evaluation of carbohydrate-functionalized cyclodextrins and liposomes for hepatocyte-specific targeting 
Gonçalo J. L. Bernardes, Raghavendra Kikkeri, Maha Maglinao, Paola Laurino, Mayeul Collot, Sung You Hong, Bernd Lepenies and Peter H. Seeberger 
Org. Biomol. Chem., 2010, 8, 4987-4996, DOI: 10.1039/C0OB00372G, Paper  

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to OBC? Then why not submit to us today or alternatively email us your suggestions.
 

This month sees the following articles in Organic & Biomolecular Chemistry that are in the top ten most accessed:-

Recent advances in transition metal-catalyzed N-atom transfer reactions of azides
Tom G. Driver
Org. Biomol. Chem., 2010, 8, 3831 – 3846, DOI: 10.1039/c005219c, Perspective

Sequential combination of Michael and acetalization reactions: direct catalytic asymmetric synthesis of functionalized 4-nitromethyl-chromans as drug intermediates
Dhevalapally B. Ramachary and Rajasekar Sakthidevi
Org. Biomol. Chem., 2010, 8, 4259 – 4265, DOI: 10.1039/c0ob00189a, Communication

Strain-promoted double-click reaction for chemical modification of azido-biomolecules
Isao Kii, Akira Shiraishi, Toshiyuki Hiramatsu, Takeshi Matsushita, Hidehiro Uekusa, Suguru Yoshida, Makoto Yamamoto, Akira Kudo, Masatoshi Hagiwara and Takamitsu Hosoya
Org. Biomol. Chem., 2010, 8, 4051 – 4055, DOI: 10.1039/c0ob00003e, Communication

Recent advances in stereoselective glycosylation through intramolecular aglycon delivery
Akihiro Ishiwata, Yong Joo Lee and Yukishige Ito
Org. Biomol. Chem., 2010, 8, 3596 – 3608, DOI: 10.1039/c004281a, Perspective

A facile method for the synthesis of oxindole based quaternary a-aminonitriles via the Strecker reaction
Yun-Lin Liu, Feng Zhou, Jun-Jie Cao, Cong-Bin Ji, Miao Ding and Jian Zhou
Org. Biomol. Chem., 2010, 8, 3847 – 3850, DOI: 10.1039/c0ob00174k, Communication

High-throughput synthesis of azide libraries suitable for direct “click” chemistry and in situ screening
Rajavel Srinivasan, Lay Pheng Tan, Hao Wu, Peng-Yu Yang, Karunakaran A. Kalesh and Shao Q. Yao
Org. Biomol. Chem., 2009, 7, 1821 – 1828, DOI: 10.1039/b902338k

In water, on water, and by water: mimicking nature’s aldolases with organocatalysis and water
Nobuyuki Mase, Carlos F. Barbas III
Org. Biomol. Chem., 2010, 8, 4043 – 4050, DOI: 10.1039/c004970k, Perspective

Organosilicon-mediated total synthesis of the triquinane sesquiterpenes (±)-beta-isocomene and (±)-isocomene
Arndt W. Schmidt, Thomas Olpp, Elke Baum, Tina Stiffel and Hans-Joachim Knölker
Org. Biomol. Chem., 2010, DOI: 10.1039/c0ob00051e

Intramolecular cycloaddition in 6,6-spiroepoxycyclohexa-2,4-dienone: simple aromatics to (±)-Platencin
Vishwakarma Singh, Bharat Chandra Sahu, Varsha Bansal and Shaikh M. Mobin
Org. Biomol. Chem., 2010, 8, 4472 – 4481, DOI: 10.1039/c004316h

Radical stability and its role in synthesis and catalysis
Johnny Hioe and Hendrik Zipse
Org. Biomol. Chem., 2010, 8, 3609 – 3617, DOI: 10.1039/c004166a, Perspective

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Organic & Biomolecular Chemistry? Then why not submit to us today or alternatively email us your suggestions.

This month sees the following articles in Organic & Biomolecular Chemistry that are in the top ten most accessed:-

Heterocycles in organic synthesis: thiazoles and triazoles as exemplar cases of synthetic auxiliaries
Alessandro Dondoni
Org. Biomol. Chem., 2010, 8, 3366-3385, DOI: 10.1039/C002586K

In water, on water, and by water: mimicking nature’s aldolases with organocatalysis and water
Nobuyuki Mase and Carlos F. Barbas, III
Org. Biomol. Chem., 2010, 8, 4043-4050, DOI: 10.1039/C004970K

Folding and self-assembly of aromatic and aliphatic urea oligomers: Towards connecting structure and function
Lucile Fischer and Gilles Guichard
Org. Biomol. Chem., 2010, 8, 3101-3117, DOI: 10.1039/C001090A

Nitrone protecting groups for enantiopure N-hydroxyamino acids: synthesis of N-terminal peptide hydroxylamines for chemoselective ligations
S. Irene Medina, Jian Wu and Jeffrey W. Bode
Org. Biomol. Chem., 2010, 8, 3405-3417, DOI: 10.1039/C004490C

Intramolecular Michael addition reaction for the synthesis of benzylbutyrolactones
Hu He, Li-Xin Dai and Shu-Li You
Org. Biomol. Chem., 2010, 8, 3207-3210, DOI: 10.1039/B924770J

Expedient, one-pot preparation of fused indoles via CAN-catalyzed three-component domino sequences and their transformation into polyheterocyclic compounds containing pyrrolo[1,2-a]azepine fragments
Padmakar A. Suryavanshi, Vellaisamy Sridharan and J. Carlos Menéndez
Org. Biomol. Chem., 2010, 8, 3426-3436, DOI: 10.1039/C004703A

Ultrafast Grignard addition reactions in the presence of water
Gyorgyi Osztrovszky, Torkil Holm and Robert Madsen
Org. Biomol. Chem., 2010, 8, 3402-3404, DOI: 10.1039/C0OB00170H

A three-step tandem process for the synthesis of bicyclic γ-lactams
Fiona I. McGonagle, Lindsay Brown, Andrew Cooke and Andrew Sutherland
Org. Biomol. Chem., 2010, 8, 3418-3425, DOI: 10.1039/C004695G

Total synthesis of decarestrictine I and botryolide B via RCM protocol
Palakodety Radha Krishna and T. Jagannadha Rao
Org. Biomol. Chem., 2010, 8, 3130-3132, DOI: 10.1039/C004556J

Picolylamine as an organocatalyst template for highly diastereo- and enantioselective aqueous aldol reactions
Thomas C. Nugent, M. Naveed Umar and Ahtaram Bibi
Org. Biomol. Chem., 2010, 8, 4085-4089, DOI: 10.1039/C0OB00049C

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Organic & Biomolecular Chemistry? Then why not submit to us today or alternatively email us your suggestions.