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OBC 10th anniversary art gallery

17 Jul 2012

With the 10th anniversary themed issue of OBC now online we thought we would share with you a couple of the other cover suggestions that were put forward by authors for this issue.

Below is the rather striking suggestion from Brimble et al. The tree and leaves represent nature, and its dew, superimposed with their spiroacetal-triazoles, drops into a pool of tablets representing the development of new therapeutic agents.

Enantioselective synthesis of C-linked spiroacetal-triazoles as privileged natural product-like scaffolds
Jui Thiang Brian Kueh, Ka Wai Choi and Margaret A. Brimble
DOI: 10.1039/C2OB06802H

This second suggestion comes from Luh et al., featuring a decameric ladderphane in recognition of the 10 years that OBC has been published.

Double stranded polymeric ladderphanes with 16-π-electron antiaromatic metallocycle linkers
Hsin-Hua Huang , Chih-Gang Chao, Shern-Long Lee, Hung-Jen Wu, Chun-hsien Chen and Tien-Yau Luh
DOI: 10.1039/C2OB25114K

Now you’ve seen the art, why not see the science? View the entire issue, featuring 68 articles from the breadth of OBC‘s scope by leaders in the field!

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Organic & Biomolecular Chemistry 10th anniversary themed issue now online: 68 great articles!

12 Jul 2012

The 10th anniversary issue of OBC has arrived! This celebratory issue contains a massive 68 articles of great science from investigators at the forefront of current research. View the entire issue here….

This nice front cover is courtesy of Eric H. Fort and Lawrence T. Scott who report the high reactivity of dimesitylbisanthene toward bay region air oxidation, leading to a bay region quinine. Fort and Scott say that “this finding signals a warning about the potential oxygen-sensitivity of hydrogenterminated carbon nanotubes; a single oxidation of this sort on the cylindrical rim of a growing carbon nanotube would preclude further elongation of the tube by the Diels–Alder cycloaddition/rearomatization protocol and would thereby terminate the growth.”

Facile air-oxidation of large aromatic hydrocarbon bay regions to bay region quinones: predicted oxygen-sensitivity of hydrogen-terminated carbon nanotubes
Eric H. Fort and Lawrence T. Scott

Also geared towards celebrating our 10th anniversary is this inside cover from Naoki Komatsu et al., which highlights their paper reporting on the optical enrichment of single-walled carbon nanotubes (SWNTs) with (n,m) other than those so far reported, together with their simultaneous separation according to their diameters by preferential extraction of commercial SWNTs with 2,6-pyridylene-bridged chiral diporphyrin nanotweezers.

Preferential extraction of left- or right-handed single-walled carbon nanotubes by use of chiral diporphyrin nanotweezers
Gang Liu, Tatsuki Yasumitsu, Li Zhao, Xiaobin Peng, Feng Wang, Ajoy K. Bauri, Shuji Aonuma, Takahide Kimura and Naoki Komatsu

In an issue packed with work from some of the best researches around there was always going to be a lot of HOT articles included, too many to list here. So, for the complete list of the HOT articles from this issue please have a look at our recent blog highlighting them.

Finally, the entire Organic & Biomolecular Chemistry team we would like to thank all of our Associate Editors, Editorial and Advisory Board members, authors and referees, without whom none of this past decade would have been possible, and we hope to work with you all to make the next 10 years even more successful.

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HOT articles from 10th anniversary themed issue of Organic & Biomolecular Chemistry

10 Jul 2012

After much anticipation the themed issue marking the 10th anniversary of Organic & Biomolecular Chemistry will be published this week, and it’s a bumper issue full of work from many at the forefront of current research who have continued contribute to the success of OBC over the past decade.

Ahead of the issue’s publication we have prepared a FREE collection of all the HOT articles that can be found within its covers, and considering all the talent that has contributed it is quite a big collection. These will all be free to access until the end of July.

Click here for the full list

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OBC issue 29 online now: radicals, ladderane lipids and Porphyrin–DNA conjugates

05 Jul 2012

Storming the castle on the cover of this week’s issue of OBC is the communication from Dustin H. Nouri and Dean J. Tantillo (winner of the 2012 NPR Lectureship) that presents quantum chemical calculations of a possible decomposition process for ladderane lipids. Nouri and Tantillo propose that hydrogen atom abstraction next to the ladderane core can lead to the opening of the cyclobutane rings that make up the ladderane substructure, and protonation leads directly to fragmentation.

Attack of radicals and protons on ladderane lipids: quantum chemical calculations and biological implications
Dustin H. Nouri and Dean J. Tantillo
DOI: 10.1039/C2OB25717C

This interesting inside cover (left) highlights the work of Gevorg Sargsyan and Milan Balaz, who report the synthesis, self-assembly, stability, and spectroscopic studies of short alternating non-self-complementary DNA sequences 5′-(dGdA)4 and 5′-(dAdG)4 with non-charged tetraarylporphyrins covalently linked to the 5′ position of deoxyadenosine or deoxyguanosine via a phosphate or amide linker.

Porphyrin–DNA conjugates: porphyrin induced adenine–guanine homoduplex stabilization and interduplex assemblies
Gevorg Sargsyan and Milan Balaz
DOI: 10.1039/C2OB25710F

These cover articles are free to accesss for 6 weeks. Also in this issue is this HOT article, which is free to access for 4 weeks:

Locking high energy 1D chain of dichloromethane molecules containing abnormally short Cl⋯Cl contacts of 2.524 Å inside organic crystals
Feng Zhou, Haoliang Fu, Wei Qiang Ong, Ruijuan Ye, Weixing Yuan, Yu-Jing Lu, Yan-Ping Huo, Kun Zhang, Haibin Su and Huaqiang Zeng

Read the complete issue here….

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HOT: Abnormally short Cl⋯Cl contacts inside organic crystals

04 Jul 2012

This HOT Communication from Huaqiang Zeng and co-workers describes a 1D helical channel, composed of short foldamers with sticky ends that self-assemble in the solid state, that acts as a CH₂Cl₂ channel. What is interesting is that the Cl⋯Cl intermolecular distances within the channel are extraordinarily short. Zeng et al. perform computational modelling and calculate that this unusually short distance destabilises the host–guest complex by 14.94 kcal mol^-1.

This will be free to access for the next 4 weeks so why not have a look at modelling details.

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Submit a poster for Lipids and Membrane Biophysics: Faraday Discussion 161

04 Jul 2012

There’s still just time to submit a poster for Lipids and Membrane Biophysics: Faraday Discussion 161 – by the deadline date 13 July.

This Faraday Discussion will consider recent developments in the study of biomembrane structure, ordering and dynamics, with particular emphasis on the roles of lipids in these phenomena. Registration is quick and simple via our online booking system, so act today and benefit from early bird savings.

Why choose to come to a Faraday Discussion? They have a unique format – all papers are circulated in advance and all discussion contributions are recorded for publication in the abstract book after the event. You can also have your own poster space at the meeting, so submit yours now before the deadline of 13 July.

Come and discuss new experimental and theoretical findings and novel methodologies, as we focus on exploring the relevance of concepts from amphiphile self-assembly and soft matter physics to understanding biomembranes.

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ICPOC21: poster abstracts

04 Jul 2012

There is still just time to submit your poster abstract to the 21st IUPAC International Conference on Physical Organic Chemistry (ICPOC 21) but don’t delay as the deadline is 13 July.

Why join ICPOC21?

Professor Dean Tantillo, University of California, Davis (USA) is the winner of the 2011 NPR Lecture Award and will be delivering his lecture at ICPOC 21.

The NPR Lecture Award is awarded to a researcher who has made a significant contribution to the field of natural products and who has been involved with the journal. Professor Tantillo was selected for his work in the field of enzymology.

In addition to the outstanding plenary sessions, there will be three parallel sessions over the five days comprising invited lectures and contributed talks, as well as poster sessions.

A broad range of scientists from across the whole community who share a quantitative perspective on chemistry will be there, providing an opportunity to discuss and celebrate the current status, development, and the future of physical organic chemistry.

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10 of the best: Synthesis in Organic & Biomolecular Chemistry

02 Jul 2012

In this addition of OBC’s ’10 of the best’ we are bringing you a selection of 10 of our most highly cited synthesis articles. As with the other blogs, every single one will be free to access for you to enjoy until July 11th.

Design, synthesis and photophysical studies of simple fluorescent anion PET sensors using charge neutral thiourea receptors
Thorfinnur Gunnlaugsson, Anthony P. Davis, Gillian M. Hussey, Juliann Tierney and Mark Glynn
DOI: 10.1039/B404706K

The small peptide-catalyzed direct asymmetric aldol reaction in water
Pawel Dziedzic, Weibiao Zou, Jonas Háfren and Armando Córdova
DOI: 10.1039/B515880J

Synthesis of protein–polymer conjugates
Karina L. Heredia and Heather D. Maynard
DOI: 10.1039/B612355D

Advanced organic synthesis using microreactor technology
Batoul Ahmed-Omer, Johan C. Brandt and Thomas Wirth
DOI: 10.1039/B615072A

Diversity-oriented synthesis; a challenge for synthetic chemists
David R. Spring
DOI: 10.1039/B310752N

Asymmetric catalysis for the construction of quaternary carbon centres: nucleophilic addition on ketones and ketimines
Olivier Riant and Jérôme Hannedouche
DOI: 10.1039/B617746H

Recent approaches towards the asymmetric synthesis of α,α-disubstituted α-amino acids
Henning Vogt and Stefan Bräse
DOI: 10.1039/B611091F

Synthesis and photophysical evaluation of charge neutral thiourea or urea based fluorescent PET sensors for bis-carboxylates and pyrophosphate
Thorfinnur Gunnlaugsson, Anthony P. Davis, John E. O’Brien and Mark Glynn
DOI: 10.1039/B409018G

Syntheses of polysubstituted furans: recent developments
Stefan F. Kirsch
DOI: 10.1039/B602596J

Accelerated asymmetric transfer hydrogenation of aromatic ketones in water
Xiaofeng Wu, Xiaoguang Li, William Hems, Frank King and Jianliang Xiao
DOI: 10.1039/B403627A

Missed our other 10th anniversary posts? Take a look here for more of our top cited work from the past 10 years.

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2011 Impact Factor for OBC, MedChemComm & NPR

29 Jun 2012

The 2011 Journal Citation Reports ® (Thomson Reuters, 2012) have just been released, which showed:

Organic & Biomolecular Chemistry: 3.696

MedChemComm: 2.8 (Partial IF only, based on five issues)

Natural Product Reports: 9.79

The Cambridge Editorial Office would like to thank everyone involved for their hard work and dedication to all three journals over the years. In particular, we would like to thank all of our Associate Editors, Editorial and Advisory Board members, authors and referees, without whom none of this would have been possible.

With another successful year in the bag, we hope you will join us in making this year even better…

Read more about the 2011 Impact Factors from across RSC Publishing on the RSC Publishing Blog.

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View OBC issue 28 today – it’s out now!

28 Jun 2012

The front cover of this issue of OBC highlights the work of Tirumala G. Varadarajua and Jih Ru Hwu, demonstrating an efficient and convergent route for the synthesis of the natural product (+)-lithospermic acid, developing two different synthetic routes for the diastereoselective synthesis of the trans-dihydrobenzo[b]furan segment of lithospermic acid.

Synthesis of anti-HIV lithospermic acid by two diverse strategies
Tirumala G. Varadaraju and Jih Ru Hwu
DOI: 10.1039/C2OB25575H

The Communication highlighted on the inside cover of this issue comes from Pandi Muthupandi and Govindasamy Sekar, Indian Institute of Technology Madras, and presents the synthesis of an unusual dinuclear chiral iron complex that was used to asymmetrically hydrophosphorylate aldehydes to synthesis optically active α-hydroxy phosphonates.

Synthesis of an unusual dinuclear chiral iron complex and its application in asymmetric hydrophosphorylation of aldehydes
Pandi Muthupandi and Govindasamy Sekar
DOI: 10.1039/C2OB25810B

Other great content in this week’s issue of OBC includes:

Emerging Area
Chiral quaternary phosphonium salts: a new class of organocatalysts
Dieter Enders and Thanh Vinh Nguyen
DOI: 10.1039/C2OB25823D

Perspective
Self-assembly driven by an aromatic primary amide motif
Myungeun Seo, Jeyoung Park and Sang Youl Kim
DOI: 10.1039/C2OB25117E

Read the FUL ISSUE today!

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Organic & Biomolecular Chemistry Blog

Author Archive

OBC 10th anniversary art gallery

Organic & Biomolecular Chemistry 10th anniversary themed issue now online: 68 great articles!

HOT articles from 10th anniversary themed issue of Organic & Biomolecular Chemistry

OBC issue 29 online now: radicals, ladderane lipids and Porphyrin–DNA conjugates

HOT: Abnormally short Cl⋯Cl contacts inside organic crystals

Submit a poster for Lipids and Membrane Biophysics: Faraday Discussion 161

ICPOC21: poster abstracts

10 of the best: Synthesis in Organic & Biomolecular Chemistry

2011 Impact Factor for OBC, MedChemComm & NPR

View OBC issue 28 today – it’s out now!

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