Archive for July, 2014

Recent HOT Organic & Biomolecular Chemistry articles

Check out the following HOT articles, these have been made free to access for a limited time:

Synthesis and immunological effects of heroin vaccines
Fuying Li, Kejun Cheng, Joshua F. G. Antoline, Malliga R. Iyer, Gary R. Matyas, Oscar B. Torres, Rashmi Jalah, Zoltan Beck, Carl R. Alving, Damon A. Parrish, Jeffrey R. Deschamps, Arthur E. Jacobson and Kenner C. Rice
Org. Biomol. Chem., 2014, Advance Article
DOI: 10.1039/C4OB01053A

Synthesis and immunological effects of heroin vaccines

Free to access until 21st August 2014


6-Azido hyacinthacine A2 gives a straightforward access to the first multivalent pyrrolizidine architectures
Giampiero D’Adamio, Camilla Parmeggiani, Andrea Goti, Antonio J. Moreno-Vargas, Elena Moreno-Clavijo, Inmaculada Robina and Francesca Cardona
Org. Biomol. Chem., 2014,12, 6250-6266
DOI: 10.1039/C4OB01117A

6-Azido hyacinthacine A2 gives a straightforward access to the first multivalent pyrrolizidine architectures

Free to access until 21st August 2014


Relative contractile motion of the rings in a switchable palindromic [3]rotaxane in aqueous solution driven by radical-pairing interactions
Leah S. Witus, Karel J. Hartlieb, Yuping Wang, Aleksandrs Prokofjevs, Marco Frasconi, Jonathan C. Barnes, Edward J. Dale, Albert C. Fahrenbach and J. Fraser Stoddart
Org. Biomol. Chem., 2014,12, 6089-6093
DOI: 10.1039/C4OB01228C

Relative contractile motion of the rings in a switchable palindromic [3]rotaxane in aqueous solution driven by radical-pairing interactions

Free to access until 21st August 2014


Catalytic control over the formation of supramolecular materials
Rienk Eelkema and Jan H. van Esch
Org. Biomol. Chem., 2014, Advance Article
DOI: 10.1039/C4OB01108B

Catalytic control over the formation of supramolecular materials

Free to access until 21st August 2014


Comparison of the substrate selectivity and biochemical properties of human and bacterial γ-butyrobetaine hydroxylase
Anna M. Rydzik, Ivanhoe K. H. Leung, Grazyna T. Kochan, Nikita D. Loik, Luc Henry, Michael A. McDonough, Timothy D. W. Claridge and Christopher J. Schofield
Org. Biomol. Chem., 2014, Advance Article
DOI: 10.1039/C4OB01167H

Comparison of the substrate selectivity and biochemical properties of human and bacterial γ-butyrobetaine hydroxylase

Free to access until 21st August 2014


Diaporine, a novel endophyte-derived regulator of macrophage differentiation
Hao Chen Wu, Hui Ming Ge, Le Yun Zang, Yun Cheng Bei, Zhi Yuan Niu, Wei Wei, Xiu Jing Feng, Sen Ding, Seik Weng Ng, Ping Ping Shen and Ren Xiang Tan
Org. Biomol. Chem., 2014, Advance Article
DOI: 10.1039/C4OB01123F

Diaporine, a novel endophyte-derived regulator of macrophage differentiation

Free to access until 21st August 2014


New reagents for detecting free radicals and oxidative stress
Mina Barzegar Amiri Olia, Carl H. Schiesser and Michelle K. Taylor
Org. Biomol. Chem., 2014, Advance Article
DOI: 10.1039/C4OB01172D

New reagents for detecting free radicals and oxidative stress

Free to access until 21st August 2014

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14th Anglo-Italian Meeting on Heterocyclic Chemistry

The 14th Anglo-Italian Meeting on Heterocyclic Chemistry, organised by the Heterocyclic & Synthesis Group in collaboration with the Italian Chemical Society, recently took place.

14th Anglo-Italian Meeting on Heterocyclic Chemistry conference photo 2014

It was an excellent meeting, held at Cumberland Lodge in Windsor Great Park, with around 50 participants, equally split between the two countries. There were some excellent lectures, including plenaries from:

  • Professor Stephen Clark (University of Glasgow)
  • Professor Sabine Flitsch (University of Manchester)
  • Dr King Kuok (Mimi) Hii (Imperial College London)
  • Professor Emanuela Licandro (University of Milan)
  • Professor Andrea Pace (University of Palermo)
  • Professor Claudio Trombini (University of Bologna)

Our congratulations go to  Susan Lepri from University of Perugia who won our poster prize.

Susan receiving her prize from Professor Chris Willis (Heterocyclic Group) and Professor Giuseppe Musumarra (Italian Chemical Society)

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Recent HOT Organic & Biomolecular Chemistry articles

Enantioselective synthesis of spiroacetals: the conquest of a long-sought goal in asymmetric catalysis
Lara Cala, Francisco J. Fañanás and Félix Rodríguez  
Org. Biomol. Chem., 2014,12, 5324-5330
DOI: 10.1039/C4OB00737A

Enantioselective synthesis of spiroacetals: the conquest of a long-sought goal in asymmetric catalysis

Free to access until 1st August 2014


Multivalent glycosylated nanoparticles for studying carbohydrate–protein interactions
Avijit K. Adak, Hong-Jyune Lin and Chun-Cheng Lin
Org. Biomol. Chem., 2014, Advance Article
DOI: 10.1039/C4OB00827H

Multivalent glycosylated nanoparticles for studying carbohydrate–protein interactions

Free to access until 1st August 2014


A simple approach to pyrrolylimidazole derivatives by azirine ring expansion with imidazolium ylides
Alexander F. Khlebnikov, Olesya A. Tomashenko, Liya D. Funt and Mikhail S. Novikov  
Org. Biomol. Chem., 2014, Advance Article
DOI: 10.1039/C4OB00865K

A simple approach to pyrrolylimidazole derivatives by azirine ring expansion with imidazolium ylides

Free to access until 1st August 2014


Enantioselective palladium catalyzed conjugate additions of ortho-substituted arylboronic acids to β,β-disubstituted cyclic enones: total synthesis of herbertenediol, enokipodin A and enokipodin B
Jeffrey Buter, Renée Moezelaar and Adriaan J. Minnaard  
Org. Biomol. Chem., 2014, Advance Article
DOI: 10.1039/C4OB01085J

Enantioselective palladium catalyzed conjugate additions of ortho-substituted arylboronic acids to β,β-disubstituted cyclic enones: total synthesis of herbertenediol, enokipodin A and enokipodin B

Free to access until 1st August 2014


Conversion of S-phenylsulfonylcysteine residues to mixed disulfides at pH 4.0: utility in protein thiol blocking and in protein-S-nitrosothiol detection
B. D. Reeves, N. Joshi, G. C. Campanello, J. K. Hilmer, L. Chetia, J. A. Vance, J. N. Reinschmidt, C. G. Miller, D. P. Giedroc, E. A. Dratz, D. J. Singel and P. A. Grieco  
Org. Biomol. Chem., 2014, Advance Article
DOI: 10.1039/C4OB00995A

Conversion of S-phenylsulfonylcysteine residues to mixed disulfides at pH 4.0: utility in protein thiol blocking and in protein-S-nitrosothiol detection

Free to access until 1st August 2014


A tryptophan responsive fluorescent and wettable dual-signal switch
Xiaoyan Zhang, Jing Li, Ningmei Feng, Li Luo, Zhen Dai, Li Yang, Demei Tian and Haibing Li
Org. Biomol. Chem., 2014, Advance Article
DOI: 10.1039/C4OB00792A

A tryptophan responsive fluorescent and wettable dual-signal switch

Free to access until 1st August 2014

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RSC Organic Division Poster Symposium 2014

RSC Organic Division Poster Symposium 2014, headline sponsored by F. Hoffmann-La Roche, Ltd.

The poster symposium, for final year organic chemistry PhD students, will take place at The Royal Society of Chemistry, Burlington House, London on Monday 01 December 2014.

The symposium offers final year PhD students a chance to showcase their research to their peers, leading academics and industrial chemists, and is open to all branches of organic chemistry. The symposium has a tradition of being the most competitive and highly regarded organic chemistry symposium for PhD students in the UK and ROI and we would like to thank F. Hoffmann-La Roche, Ltd. for their generous support of the event.

There will be a first prize of £500, two runner-up prizes of £250, and a “selected by Industry Prize”. Industrial delegates will make this selection by considering the research’s potential for application in an industrial context; the winner will also receive a prize of £500.

Closing date for submissions is Wednesday 01 October 2014.
For more information and to submit your abstract go to http://rsc.li/organic-poster

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