HOT: Synthesis of polysubstituted furanonaphthoquinones

In this HOT paper, Wenwei Lin and colleagues at National Taiwan Normal University report an efficient and versatile synthesis of polysubstituted furanonaphthoquinones. The strategy developed by Lin et al. is based on the synthesis of a series of novel poly-functionalized phosphorus zwitterions via three-component reactions, which are then involved in an intramolecular Wittig reaction.

The flexibility of this synthesis is such that furanonaphthoquinones with various substituents at the 2- and 3-positions of the furan segment can be produced.

To find out more about this method download the article for free today.

A versatile and practical method for regioselective synthesis of polysubstituted furanonaphthoquinones
Zong-Ze Wu, Yeong-Jiunn Jang, Chia-Jui Lee, Yen-Te Lee and Wenwei Lin
DOI: 10.1039/C2OB26986D

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