In this HOT paper, Wenwei Lin and colleagues at National Taiwan Normal University report an efficient and versatile synthesis of polysubstituted furanonaphthoquinones. The strategy developed by Lin et al. is based on the synthesis of a series of novel poly-functionalized phosphorus zwitterions via three-component reactions, which are then involved in an intramolecular Wittig reaction.
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A versatile and practical method for regioselective synthesis of polysubstituted furanonaphthoquinones
Zong-Ze Wu, Yeong-Jiunn Jang, Chia-Jui Lee, Yen-Te Lee and Wenwei Lin