Featuring on the front cover is a paper from Günter Haufe and colleagues, described by the reviewers as being an important contribution to the field of organofluorine chemistry. Haufe et al. present results of the reactions of β-alkoxyvinyl polyfluoroalkyl ketones with ethyl isocyanoacetate and potassium tert-butoxide, which are strongly dependent on the structure of the starting enones, and the application of this reaction to the synthesis of new fluorinated pyrroles.
Reactions of β-alkoxyvinyl polyfluoroalkyl ketones with ethyl isocyanoacetate and its use for the synthesis of new polyfluoroalkyl pyrroles and pyrrolidines
Ivan S. Kondratov, Violetta G. Dolovanyuk, Nataliya A. Tolmachova, Igor I. Gerus, Klaus Bergander, Roland Fröhlich and Günter Haufe
DOI: 10.1039/C2OB26176F
This bright image on the inside cover is courtesy of Kristin Bowman-James and co-workers at the University of Kansas. Bowman-James et al. summarise results from previous studies on the stability and reactivity of the sulfur mustard and its surrogates toward hydrolysis and nucleophilic attack, and add results of their own on the reactivity of this class of molecules with simple nucleophiles in non-polar solvents, assessing their behaviour in the absence of competing solvation effects.
Sulfur, oxygen, and nitrogen mustards: stability and reactivity
Qi-Qiang Wang, Rowshan Ara Begum, Victor W. Day and Kristin Bowman-James
DOI: 10.1039/C2OB26482J
Read the entire issue on our webpage, and don’t forget that the articles featuring on the covers are free for you to download for the next 6 weeks.
