Organic & Biomolecular Chemistry Blog

In this HOT Communication Adam R. Urbach and colleagues, Trinity University, present a convenient approach for the quantitative removal of the synthetic host cucurbit[8]uril from aqueous mixtures using a sepharose resin coated in memantine groups to selectively isolate cucurbit[8]uril in the presence of competing hosts and guests. The “cucurbit[8]uril sponge” can separate cucurbit[8]uril from cucurbit[6]uril and reverse the cucurbit[8]uril-mediated dimerization of peptides.

This communication is free to access for the next 4 weeks!

A cucurbit[8]uril sponge
Vijayakumar Ramalingam, Sharon K. Kwee, Lisa M. Ryno and Adam R. Urbach
DOI: 10.1039/C2OB26774H