OBC issue 39 out now

An overview of this week’s issue of Organic & Biomolecular Chemistry

On the front cover of this issue of OBC Chun Liu and colleagues, at Dalian University of Technology, report a fast and efficient ligand-free protocol for the synthesis of N-heteroaryl substituted 9-arylcarbazolyl derivatives under aerobic and aqueous conditions using a palladium catalyst.

A highly efficient and aerobic protocol for the synthesis of N-heteroaryl substituted 9-arylcarbazolyl derivatives via a palladium-catalyzed ligand-free Suzuki reaction
Xiaofeng Rao, Chun Liu, Jieshan Qiu and Zilin Jin

The inside cover features the work of James D. White and co-workers, Oregon State University, describing the total synthesis of phorboxazole A, one of the most potent antitumor marine macrolide natural products with a challenging structure.

Total synthesis of the marine toxin phorboxazole A using palladium(II)-mediated intramolecular alkoxycarbonylation for tetrahydropyran synthesis
Punlop Kuntiyong, Tae Hee Lee, Christian L. Kranemann and James D. White

Also featuring in this issue are 4 Communications: 

Rationally-designed fluorescent lysine riboswitch probes
Pradeep Budhathoki, Lina F. Bernal-Perez, Onofrio Annunziata and Youngha Ryu

A novel copper-catalyzed reductive coupling of N-tosylhydrazones with H-phosphorus oxides

Lei Wu, Xiǎo Zhang, Qing-Qing Chen and An-Kun Zhou

Rapid synthesis of substituted pyrrolines and pyrrolidines by nucleophilic ring closure at activated oximes

Nandkishor Chandan, Amber L. Thompson and Mark G. Moloney

KI-catalyzed imidation of sp3 C–H bond adjacent to amide nitrogen atom

Zhi-Qi Lao, Wen-He Zhong, Qing-Hua Lou, Zhong-Jun Li and Xiang-Bao Meng

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