UK scientists have synthesised the core ring structure of the fargenin/fargenone family of (biologically active) natural products. This, they say, is the first synthetic step towards this family of compounds. The strategy they devised uses an elegant cascade concept, which while unfortunately not leading to the desired natural product itself, still proves the concept validity and provides a first entry to this class of natural products.
A strategy for the synthesis of the fargenone/fargenin family of natural products: Synthesis of the tricyclic core
Ross Matthew Denton
DOI: 10.1039/C2OB25489A
