In this HOT OBC paper Heiko Ihmels and colleagues at University of Siegen present the fluorimetric detection of Mg2+ and DNA with 9-(alkoxyphenyl)benzo[b]-quinolizinium derivatives. Although there are quite a few fluorescent probes that enable the detection of different analytes from the same class of compounds, probes that allow optical detection of different types of analytes are much rarer. In this paper Heiko Ihmels et al. show that a benzo[b]quinolizinium-benzo-15-crown-5 ether conjugate can be used for the detection of both Mg2+ and DNA by a significant light-up effect and with different emission wavelengths for the two different analytes.
The authors investigated the light-up mechanism by comparison with the photophysical properties of methoxyphenyl-substituted benzo[b]quinolizinium reference compounds, revealing that the position of the methoxy functionality had a significant influence on the emission properties of the donor–acceptor systems.
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Fluorimetric detection of Mg2+ and DNA with 9-(alkoxyphenyl)benzo[b]quinolizinium derivatives
Maoqun Tian, Heiko Ihmels and Shite Ye
Org. Biomol. Chem., 2012, 10, 3010–3018
DOI: 10.1039/C2OB06948B
