Aline Banchet-Cadeddu and colleagues at Universite de Reims Champagne-Ardenne and Universite de Strasbourg, present an up-to-date library of analogues of KRN 7000, a potent synthetic galactosylceramide that activate the invariant NKT immune cells.
They have collected recent breakthroughs done in crystallography and molecular modelling, and
related them to the available biological results.
This review will help the scientific community in their KRN research.
The stimulating adventure of KRN 7000
Aline Banchet-Cadeddu, Eric Hénon, Manuel Dauchez, Jean-Hugues Renault, Fanny Monneaux and Arnaud Haudrechy
Org. Biomol. Chem., 2011, 9, 3080-3104
DOI: 10.1039/C0OB00975J
