Sebastien G. Gouin and his team at University of Nantes, France, review some of the important structural features in the synthesis of multivalent glycoconjugates for a tight binding with specific lectins.
Read this review on multivalent inhibitors of lectins from a different and very interesting point of view: how the scaffold influences potency.
Insights in the rational design of synthetic multivalent glycoconjugates as lectin ligands
David Deniaud, Karine Julienne and Sébastien G. Gouin
Org. Biomol. Chem., 2011, 9, 966-979
DOI: 10.1039/C0OB00389A, Perspective