Organic & Biomolecular Chemistry Blog

Thomas Nugent and colleagues at Jacobs University describe the use of a three component catalyst, an amino acid, a base and a hydrogen bond donor, to form quaternary C-C bonds in this paper that is the front cover of the first issue of Organic & Biomolecular Chemistry in 2011.

Read this free to access until mid-January paper to find out more about the catalytic enantioselective formation of an important class of Michael products bearing quaternary carbons.

Practical access to highly enantioenriched quaternary carbon Michael adducts using simple organocatalysts
Thomas C. Nugent, Mohammad Shoaib and Amna Shoaib
 Org. Biomol. Chem., 2011, 9, 52-56
DOI: 10.1039/C0OB00822B, Communication