Front Cover Issue 20: Proton as the electrophile

This colourful and arty cover by Chunling Fu, Shengming Ma and colleagues shows the mechanism of a highly regio- and stereo- selective hydration of 1,2-allenylic sulfoxides.

In this reaction, the proton acts as the electrophile and water coming from the solvent attacks the sulfinyl group.
Not convinced yet?  There are even crystal structures to prove it!

Download the article for free until 10th November

Studies on highly regio- and stereoselective hydration of 1,2-allenylic sulfoxides
Zhao Fang, Chao Zhou, Chunling Fu and Shengming Ma
Org. Biomol. Chem., 2010, 8, 4554-4561
DOI: 10.1039/C0OB00007H

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