HOT: Deuterium as a protecting group

Can Deuterium act as a protecting group to prevent unwanted hydrogen atom transfers?

Mark Wood and colleagues have the answer here.

Reviewers were very impressed with it and we made it a HOT article.

Curious? Find out more! Free to access until the end of September.

Synthetic use of the primary kinetic isotope effect in hydrogen atom transfer: generation of α-aminoalkyl radicals
Mark E. Wood, Sabine Bissiriou, Christopher Lowe, Andrew M. Norrish, Katell Sénéchal, Kim M. Windeatt, Simon J. Coles and Michael B. Hursthouse
Org. Biomol. Chem., 2010, Advance Article
DOI: 10.1039/C0OB00205D , Paper

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