Natural Products Blog

This month sees the following articles in Natural Product Reports that are in the top ten most accessed:

Hot off the Press
Robert A. Hill and Andrew Sutherland
Nat. Prod. Rep., 2011, 28, 1621-1625
DOI: 10.1039/C1NP90035H

Natural products and Pharma 2011: Strategic changes spur new opportunities
Guy T. Carter
Nat. Prod. Rep., 2011, 28, 1783-1789
DOI: 10.1039/C1NP00033K

Hypervalent iodine reagents in the total synthesis of natural products
Luiz F. Silva, Jr. and Berit Olofsson
Nat. Prod. Rep., 2011, 28, 1722-1754
DOI: 10.1039/C1NP00028D

Flavonoids and their glycosides, including anthocyanins
Nigel C. Veitch and Renée J. Grayer
Nat. Prod. Rep., 2011, 28, 1626-1695
DOI: 10.1039/C1NP00044F

Diterpenoids of terrestrial origin
James R. Hanson
Nat. Prod. Rep., 2011, 28, 1755-1772
DOI: 10.1039/C1NP90021H

Pathways for degradation of lignin in bacteria and fungi
Timothy D. H. Bugg, Mark Ahmad, Elizabeth M. Hardiman and Rahman Rahmanpour
Nat. Prod. Rep., 2011, Advance Article
DOI: 10.1039/C1NP00042J

Natural products in anti-obesity therapy
Ilze Vermaak, Alvaro M. Viljoen and Josias H. Hamman
Nat. Prod. Rep., 2011, 28, 1493-1533
DOI: 10.1039/c1np00035g

Marine natural products
John W. Blunt, Brent R. Copp, Murray H. G. Munro, Peter T. Northcote and Michèle R. Prinsep
Nat. Prod. Rep., 2011, 28, 196-268
DOI: 10.1039/C005001F

Marine chemical ecology
Valerie J. Paul, Melany P. Puglisi and Raphael Ritson-Williams
Nat. Prod. Rep., 2006, 23, 153-180
DOI: 10.1039/B404735B

Natural sesquiterpenoids
Braulio M. Fraga
Nat. Prod. Rep., 2011, 28, 1580-1610
DOI: 10.1039/C1NP00046B

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Natural Product Reports? Then why not submit to us today or alternatively email us your suggestions.

This month sees the following articles in Natural Product Reports that are in the top ten most accessed:

Natural sesquiterpenoids
Braulio M. Fraga
Nat. Prod. Rep., 2011, 28, 1580-1610
DOI: 10.1039/C1NP00046B

Hypervalent iodine reagents in the total synthesis of natural products
Luiz F. Silva, Jr. and Berit Olofsson
Nat. Prod. Rep., 2011, Advance Article
DOI: 10.1039/C1NP00028D

Platensimycin and its relatives: A recent story in the struggle to develop new naturally derived antibiotics
Muhammad Saleem, Hidayat Hussain, Ishtiaq Ahmed, Teunis van Ree and Karsten Krohn
Nat. Prod. Rep., 2011, 28, 1534-1579
DOI: 10.1039/C1NP00010A

Natural products in anti-obesity therapy
Ilze Vermaak, Alvaro M. Viljoen and Josias H. Hamman
Nat. Prod. Rep., 2011, 28, 1493-1533
DOI: 10.1039/c1np00035g

Similar interactions of natural products with biosynthetic enzymes and therapeutic targets could explain why nature produces such a large proportion of existing drugs
Esther Kellenberger, Andreas Hofmann and Ronald J. Quinn
Nat. Prod. Rep., 2011, 28, 1483-1492
DOI: 10.1039/C1NP00026H

Flavonoids and their glycosides, including anthocyanins
Nigel C. Veitch and Renée J. Grayer
Nat. Prod. Rep., 2011, Advance Article
DOI: 10.1039/C1NP00044F

Marine natural products
John W. Blunt, Brent R. Copp, Murray H. G. Munro, Peter T. Northcote and Michèle R. Prinsep
Nat. Prod. Rep., 2011, 28, 196-268
DOI: 10.1039/C005001F

Diterpenoids of terrestrial origin
James R. Hanson
Nat. Prod. Rep., 2011, Advance Article
DOI: 10.1039/C1NP90021H

Hot off the Press
Robert A. Hill and Andrew Sutherland
Nat. Prod. Rep., 2011, 28, 1345-1349
DOI: 10.1039/C1NP90027G

Plant volatiles: Production, function and pharmacology
Massimo E. Maffei, Jürg Gertsch and Giovanni Appendino
Nat. Prod. Rep., 2011, 28, 1359-1380
DOI: 10.1039/C1NP00021G

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Natural Product Reports? Then why not submit to us today or alternatively email us your suggestions.

This month sees the following articles in Natural Product Reports that are in the top ten most accessed:

Natural products in anti-obesity therapy
Ilze Vermaak, Alvaro M. Viljoen and Josias H. Hamman
Nat. Prod. Rep., 2011, 28, 1493-1533
DOI: 10.1039/c1np00035g

Hot off the Press
Robert A. Hill and Andrew Sutherland
Nat. Prod. Rep., 2011, 28, 1345-1349
DOI: 10.1039/c1np90027g

Piperazic acid-containing natural products: Isolation, biological relevance and total synthesis
Alexander J. Oelke, David J. France, Tatjana Hofmann, Georg Wuitschik and Steven V. Ley
Nat. Prod. Rep., 2011, 28, 1445-1471
DOI: 10.1039/c1np00041a

Diterpenoids of terrestrial origin
James R. Hanson
Nat. Prod. Rep., 2011, Advance Article
DOI: 10.1039/c1np90021h

Marine natural products
John W. Blunt, Brent R. Copp, Murray H. G. Munro, Peter T. Northcote and Michèle R. Prinsep
Nat. Prod. Rep., 2011, 28, 196-268
DOI: 10.1039/C005001F

Plant volatiles: Production, function and pharmacology
Massimo E. Maffei, Jürg Gertsch and Giovanni Appendino
Nat. Prod. Rep., 2011, 28, 1359-1380
DOI: 10.1039/C1NP00021G

Anticancer compounds derived from fungal endophytes: their importance and future challenges
Ravindra N. Kharwar, Ashish Mishra, Surendra K. Gond, Andrea Stierle and Donald Stierle
Nat. Prod. Rep., 2011, 28, 1208-1228
DOI: 10.1039/C1NP00008J

Natural products containing a diazo group
Christopher C. Nawrat and Christopher J. Moody
Nat. Prod. Rep., 2011, 28, 1426-1444
DOI: 10.1039/C1NP00031D

Metabolic engineering is key to a sustainable chemical industry
Annabel C. Murphy
Nat. Prod. Rep., 2011, 28, 1406-1425
DOI: 10.1039/c1np00029b

Antibiotic activities of host defense peptides: more to it than lipid bilayer perturbation
Miriam Wilmes, Bruno P. A. Cammue, Hans-Georg Sahl and Karin Thevissen
Nat. Prod. Rep., 2011, 28, 1350-1358
DOI: 10.1039/C1NP00022E

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Natural Product Reports? Then why not submit to us today or alternatively email us your suggestions.

This month sees the following articles in Natural Product Reports that are in the top ten most accessed:

Anticancer compounds derived from fungal endophytes: their importance and future challenges
Ravindra N. Kharwar, Ashish Mishra, Surendra K. Gond, Andrea Stierle and Donald Stierle
Nat. Prod. Rep., 2011, 28, 1208-1228
DOI: 10.1039/C1NP00008J

Are we ready for industrial production of bioactive plant secondary metabolites utilizing endophytes?
Souvik Kusari and Michael Spiteller
Nat. Prod. Rep., 2011, 28, 1203-1207
DOI: 10.1039/C1NP00030F

Natural products containing a diazo group
Christopher C. Nawrat and Christopher J. Moody
Nat. Prod. Rep., 2011, 28, 1426-1444
DOI: 10.1039/C1NP00031D

The regulation of the secondary metabolism of Streptomyces: new links and experimental advances
Gilles P. van Wezel and Kenneth J. McDowall
Nat. Prod. Rep., 2011, 28, 1311-1333
DOI: 10.1039/C1NP00003A

Plant volatiles: Production, function and pharmacology
Massimo E. Maffei, Jürg Gertsch and Giovanni Appendino
Nat. Prod. Rep., 2011, 28, 1359-1380
DOI: 10.1039/C1NP00021G

Marine natural products
John W. Blunt, Brent R. Copp, Murray H. G. Munro, Peter T. Northcote and Michèle R. Prinsep
Nat. Prod. Rep., 2011, 28, 196-268
DOI: 10.1039/C005001F

Hot off the press
Robert A. Hill and Andrew Sutherland
Nat. Prod. Rep., 2011, 28, 1031-1034
DOI: 10.1039/C1NP90013G

Antibiotic activities of host defense peptides: more to it than lipid bilayer perturbation
Miriam Wilmes, Bruno P. A. Cammue, Hans-Georg Sahl and Karin Thevissen
Nat. Prod. Rep., 2011, 28, 1350-1358
DOI: 10.1039/C1NP00022E

Biosynthesis, asymmetric synthesis, and pharmacology, including cellular targets, of the pyrrole-2-aminoimidazole marine alkaloids
Ali Al-Mourabit, Manuel A. Zancanella, Supriya Tilvi and Daniel Romo
Nat. Prod. Rep., 2011, 28, 1229-1260
DOI: 10.1039/C0NP00013B

Perspectives on the structural and biosynthetic interrelationships between oxygenated furanocembranoids and their polycyclic congeners found in corals
Yi Li and Gerald Pattenden
Nat. Prod. Rep., 2011, 28, 1269-1310
DOI: 10.1039/C1NP00023C

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Natural Product Reports? Then why not submit to us today or alternatively email us your suggestions.

This month sees the following articles in NPR that are in the top ten most accessed:-

Anticancer compounds derived from fungal endophytes: their importance and future challenges 
Ravindra N. Kharwar, Ashish Mishra, Surendra K. Gond, Andrea Stierle and Donald Stierle  
Nat. Prod. Rep., 2011, Advance Article DOI: 10.1039/C1NP00008J  

Muscarine, imidazole, oxazole, and thiazole alkaloids 
Zhong Jin 
Nat. Prod. Rep., 2011, Advance Article DOI: 10.1039/C0NP00074D  

Amaryllidaceae and Sceletium alkaloids 
Zhong Jin 
Nat. Prod. Rep., 2011, Advance Article DOI: 10.1039/C0NP00073F  

Application of NMR methods to the study of the interaction of natural products with biomolecular receptors 
Luis P. Calle, F. Javier Cañada and Jesús Jiménez-Barbero 
Nat. Prod. Rep., 2011, Advance Article DOI: 10.1039/C0NP00071J  

Natural products as a source of Alzheimer’s drug leads 
Philip Williams, Analia Sorribas and Melanie-Jayne R. Howes 
Nat. Prod. Rep., 2011, 28, 48-77 DOI: 10.1039/C0NP00027B, Review 

Hot off the press 
Robert A. Hill and Andrew Sutherland 
Nat. Prod. Rep., 2011, 28, 659-662 DOI: 10.1039/C1NP90009A, Hot off the Press Article 

Anti-influenza agents from Traditional Chinese Medicine 
Hu Ge, Yi-Fei Wang, Jun Xu, Qiong Gu, Hai-Bo Liu, Pei-Gen Xiao, Jiaju Zhou, Yanhuai Liu, Zirong Yang and Hua Su 
Nat. Prod. Rep., 2010, 27, 1758-1780 DOI: 10.1039/C0NP00005A  

Marine natural products: Synthetic aspects 
Jonathan C. Morris and Andrew J. Phillips 
Nat. Prod. Rep., 2011, 28, 269-289 DOI: 10.1039/C0NP00066C, Review 

Synthesis of ellagitannin natural products 
Laurent Pouységu, Denis Deffieux, Gaëlle Malik, Anna Natangelo and Stéphane Quideau 
Nat. Prod. Rep., 2011, 28, 853-874 DOI: 10.1039/C0NP00058B  

Propolis research and the chemistry of plant products 
Antonio Salatino, Caroline C. Fernandes-Silva, Adne Abbud Righi and Maria Luiza F. Salatino 
Nat. Prod. Rep., 2011, 28, 925-936 DOI: 10.1039/C0NP00072H  

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to NPR? Then why not submit to us today or alternatively email us your suggestions.
  

This month sees the following articles in NPR that are in the top ten most accessed:-

Hot off the press 
Robert A. Hill and Andrew Sutherland 
Nat. Prod. Rep., 2011, 28, 659-662 DOI: 10.1039/C1NP90009A, Hot off the Press Article 

Isolation and analysis of ginseng: advances and challenges 
Lian-Wen Qi, Chong-Zhi Wang and Chun-Su Yuan 
Nat. Prod. Rep., 2011, 28, 467-495 DOI: 10.1039/C0NP00057D, Review 

Natural products as a source of Alzheimer’s drug leads 
Philip Williams, Analia Sorribas and Melanie-Jayne R. Howes 
Nat. Prod. Rep., 2011, 28, 48-77 DOI: 10.1039/C0NP00027B, Review 

Marine natural products: Synthetic aspects 
Jonathan C. Morris and Andrew J. Phillips 
Nat. Prod. Rep., 2011, 28, 269-289 DOI: 10.1039/C0NP00066C, Review 

Natural withanolides: an overview 
Li-Xia Chen, Hao He and Feng Qiu 
Nat. Prod. Rep., 2011, 28, 705-740 DOI: 10.1039/C0NP00045K, Review 

N-Containing compounds of macromycetes 
Meng-Yuan Jiang, Tao Feng and Ji-Kai Liu 
Nat. Prod. Rep., 2011, 28, 783-808 DOI: 10.1039/C0NP00006J, Review 

A sea of biosynthesis: marine natural products meet the molecular age 
Amy L. Lane and Bradley S. Moore 
Nat. Prod. Rep., 2011, 28, 411-428 DOI: 10.1039/C0NP90032J, Review 

Natural products and Chagas’ disease: a review of plant compounds studied for activity against Trypanosoma cruzi 
Erika Izumi, Tânia Ueda-Nakamura, Benedito Prado Dias Filho, Valdir Florêncio Veiga Júnior and Celso Vataru Nakamura 
Nat. Prod. Rep., 2011, 28, 809-823 DOI: 10.1039/C0NP00069H, Review 

Natural glycoconjugates with antitumor activity 
Barbara La Ferla, Cristina Airoldi, Cristiano Zona, Alexandre Orsato, Francisco Cardona, Silvia Merlo, Erika Sironi, Giuseppe D’Orazio and Francesco Nicotra 
Nat. Prod. Rep., 2011, 28, 630-648 DOI: 10.1039/C0NP00055H, Review 

Ergot alkaloids: structure diversity, biosynthetic gene clusters and functional proof of biosynthetic genes 
Christiane Wallwey and Shu-Ming Li 
Nat. Prod. Rep., 2011, 28, 496-510 DOI: 10.1039/C0NP00060D, Review 

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to NPR? Then why not submit to us today or alternatively email us your suggestions.

This month sees the following articles in NPR that are in the top ten most accessed:-

Natural products as a source of Alzheimer’s drug leads 
Philip Williams, Analia Sorribas and Melanie-Jayne R. Howes 
Nat. Prod. Rep., 2011, 28, 48-77, DOI: 10.1039/C0NP00027B, Review 

Natural products and Chagas’ disease: a review of plant compounds studied for activity against Trypanosoma cruzi 
Erika Izumi, Tânia Ueda-Nakamura, Benedito Prado Dias Filho, Valdir Florêncio Veiga Júnior and Celso Vataru Nakamura 
Nat. Prod. Rep., 2011, 28, 809-823, DOI: 10.1039/C0NP00069H, Review 

Marine natural products: Synthetic aspects 
Jonathan C. Morris and Andrew J. Phillips 
Nat. Prod. Rep., 2011, 28, 269-289, DOI: 10.1039/C0NP00066C, Review 

A sea of biosynthesis: marine natural products meet the molecular age 
Amy L. Lane and Bradley S. Moore 
Nat. Prod. Rep., 2011, 28, 411-428, DOI: 10.1039/C0NP90032J, Review 

Construction of spirolactones with concomitant formation of the fused quaternary centre ? application to the synthesis of natural products 
Alexandra Bartoli, Fabien Rodier, Laurent Commeiras, Jean-Luc Parrain and Gaëlle Chouraqui 
Nat. Prod. Rep., 2011, 28, 763-782, DOI: 10.1039/C0NP00053A, Review 

N-Containing compounds of macromycetes 
Meng-Yuan Jiang, Tao Feng and Ji-Kai Liu 
Nat. Prod. Rep., 2011, 28, 783-808, DOI: 10.1039/C0NP00006J, Review 

Secondary metabolites of fungi from marine habitats 
Mostafa E. Rateb and Rainer Ebel 
Nat. Prod. Rep., 2011, 28, 290-344, DOI: 10.1039/C0NP00061B, Review 

Isolation and analysis of ginseng: advances and challenges 
Lian-Wen Qi, Chong-Zhi Wang and Chun-Su Yuan 
Nat. Prod. Rep., 2011, 28, 467-495, DOI: 10.1039/C0NP00057D, Review 

Natural disesquiterpenoids 
Zha-Jun Zhan, You-Min Ying, Lie-Feng Ma and Wei-Guang Shan 
Nat. Prod. Rep., 2011, 28, 594-629, DOI: 10.1039/C0NP00050G, Review 

Antifouling marine natural products 
Nobuhiro Fusetani 
Nat. Prod. Rep., 2011, 28, 400-410, DOI: 10.1039/C0NP00034E, Review 

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to NPR? Then why not submit to us today or alternatively email us your suggestions.

This month sees the following articles in NPR that are in the top ten most accessed:-

Marine natural products: Synthetic aspects 
Jonathan C. Morris and Andrew J. Phillips 
Nat. Prod. Rep., 2011, 28, 269-289, DOI: 10.1039/C0NP00066C, Review 

Natural products as a source of Alzheimer’s drug leads 
Philip Williams, Analia Sorribas and Melanie-Jayne R. Howes 
Nat. Prod. Rep., 2011, 28, 48-77, DOI: 10.1039/C0NP00027B, Review 

Hot off the press 
Robert A. Hill and Andrew Sutherland,
Nat. Prod. Rep., 2011, 28, 182-185, DOI: 10.1039/C0NP90038A, Hot off the Press Article 

Secondary metabolites of fungi from marine habitats 
Mostafa E. Rateb and Rainer Ebel 
Nat. Prod. Rep., 2011, 28, 290-344, DOI: 10.1039/C0NP00061B, Review 

A sea of biosynthesis: marine natural products meet the molecular age 
Amy L. Lane and Bradley S. Moore 
Nat. Prod. Rep., 2011, 28, 411-428, DOI: 10.1039/C0NP90032J, Review 

Novel macrocyclic and polycyclic norcembranoid diterpenes from Sinularia species of soft coral: Structural relationships and biosynthetic speculations 
Yi Li and Gerald Pattenden
Nat. Prod. Rep., 2011, 28, 429-440, DOI: 10.1039/C0NP00029A, Review 

Ergot alkaloids: structure diversity, biosynthetic gene clusters and functional proof of biosynthetic genes 
Christiane Wallwey and Shu-Ming Li 
Nat. Prod. Rep., 2011, 28, 496-510, DOI: 10.1039/C0NP00060D, Review 

Antifouling marine natural products 
Nobuhiro Fusetani 
Nat. Prod. Rep., 2011, 28, 400-410, DOI: 10.1039/C0NP00034E, Review 

What every chemist should know about plant names 
Roy Hubertus Johannes Erkens 
Nat. Prod. Rep., 2011, 28, 11-14, DOI: 10.1039/C0NP00042F, Viewpoint 

Natural disesquiterpenoids 
Zha-Jun Zhan, You-Min Ying, Lie-Feng Ma and Wei-Guang Shan 
Nat. Prod. Rep., 2011, 28, 594-629, DOI: 10.1039/C0NP00050G, Review 

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to NPR? Then why not submit to us today or alternatively email us your suggestions.

This month sees the following articles in NPR that are in the top ten most accessed:-

Natural products as a source of Alzheimer’s drug leads 
Philip Williams, Analia Sorribas and Melanie-Jayne R. Howes 
Nat. Prod. Rep., 2011, 28, 48-77, DOI: 10.1039/C0NP00027B, Review 

Naturally-occurring nitro compounds 
Ronald Parry, Shirley Nishino and Jim Spain 
Nat. Prod. Rep., 2011, 28, 152-167, DOI: 10.1039/C0NP00024H, Review 

What every chemist should know about plant names 
Roy Hubertus Johannes Erkens 
Nat. Prod. Rep., 2011, 28, 11-14, DOI: 10.1039/C0NP00042F, Viewpoint

Natural glycoconjugates with antitumor activity Barbara
La Ferla, Cristina Airoldi, Cristiano Zona, Alexandre Orsato, Francisco Cardona, Silvia Merlo, Erika Sironi, Giuseppe D’Orazio and Francesco Nicotra 
Nat. Prod. Rep., 2011, Advance Article, DOI: 10.1039/C0NP00055H, Review 

Chlorosulfolipids: Structure, synthesis, and biological relevance 
D. Karl Bedke and Christopher D. Vanderwal 
Nat. Prod. Rep., 2011, 28, 15-25, DOI: 10.1039/C0NP00044B, Highlight 

A sea of biosynthesis: marine natural products meet the molecular age 
Amy L. Lane and Bradley S. Moore 
Nat. Prod. Rep., 2011, 28, 411-428, DOI: 10.1039/C0NP90032J, Review 

Methods and options for the heterologous production of complex natural products 
Haoran Zhang, Brett A. Boghigian, John Armando and Blaine A. Pfeifer 
Nat. Prod. Rep., 2011, 28, 125-151, DOI: 10.1039/C0NP00037J, Review 

Recent advances in anti-HIV natural products 
Inder Pal Singh and Hardik S. Bodiwala 
Nat. Prod. Rep., 2010, 27, 1781-1800, DOI: 10.1039/C0NP00025F, Review 

Marine chemical ecology in benthic environments 
Valerie J. Paul, Raphael Ritson-Williams and Koty Sharp 
Nat. Prod. Rep., 2011, 28, 345-387, DOI: 10.1039/C0NP00040J, Review 

Anti-influenza agents from Traditional Chinese Medicine 
Hu Ge, Yi-Fei Wang, Jun Xu, Qiong Gu, Hai-Bo Liu, Pei-Gen Xiao, Jiaju Zhou, Yanhuai Liu, Zirong Yang and Hua Su 
Nat. Prod. Rep., 2010, 27, 1758-1780, DOI: 10.1039/C0NP00005A, Review 

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to NPR? Then why not submit to us today or alternatively email us your suggestions.