Natural Products Blog

Curious about which articles published in 2012 gathered most readership? Here are the Top 10 works your colleagues have been accessing in Natural Product Reports:

Marine natural products
John W. Blunt, Brent R. Copp, Robert A. Keyzers, Murray H. G. Munro and Michèle R. Prinsep
Nat. Prod. Rep., 2012, 29, 144-222
DOI: 10.1039/C2NP00090C

Recent discovery of plant-derived anti-diabetic natural products
Hsin-Yi Hung, Keduo Qian, Susan L. Morris-Natschke, Chau-Shin Hsu and Kuo-Hsiung Lee
Nat. Prod. Rep., 2012, 29, 580-606
DOI: 10.1039/C2NP00074A

Advances in Aspergillus secondary metabolite research in the post-genomic era
James F. Sanchez, Amber D. Somoza, Nancy P. Keller and Clay C. C. Wang
Nat. Prod. Rep., 2012, 29, 351-371
DOI: 10.1039/C2NP00084A

Influenza neuraminidase: A druggable target for natural products
Ulrike Grienke, Michaela Schmidtke, Susanne von Grafenstein, Johannes Kirchmair, Klaus R. Liedl and Judith M. Rollinger
Nat. Prod. Rep., 2012, 29, 11-36
DOI: 10.1039/C1NP00053E

Natural products as kinase inhibitors
Jing Liu, Yi Hu, David L. Waller, Junfeng Wang and Qingsong Liu
Nat. Prod. Rep., 2012, 29, 392-403
DOI: 10.1039/C2NP00097K

The chemical ecology of cyanobacteria
Pedro N. Leão, Niclas Engene, Agostinho Antunes, William H. Gerwick and Vitor Vasconcelos
Nat. Prod. Rep., 2012, 29, 372-391
DOI: 10.1039/C2NP00075J

Electrophilic natural products and their biological targets
Malte Gersch, Johannes Kreuzer and Stephan A. Sieber
Nat. Prod. Rep., 2012, 29, 659-682
DOI: 10.1039/C2NP20012K

The taxonomy, biology and chemistry of the fungal Pestalotiopsis genus
Xiao-Long Yang, Jing-Ze Zhang and Du-Qiang Luo
Nat. Prod. Rep., 2012, 29, 622-641
DOI: 10.1039/C2NP00073C

Aminobenzoates as building blocks for natural product assembly lines
Christopher T. Walsh, Stuart W. Haynes and Brian D. Ames
Nat. Prod. Rep., 2012, 29, 37-59
DOI: 10.1039/C1NP00072A

Strained cyclophane natural products: Macrocyclization at its limits
Tanja Gulder and Phil S. Baran
Nat. Prod. Rep., 2012, 29, 899-934
DOI: 10.1039/C2NP20034A

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This month sees the following articles in Natural Product Reports that are in the top ten most accessed:

Synthetic approaches toward sesterterpenoids
Daniel T. Hog, Robert Webster and Dirk Trauner
Nat. Prod. Rep., 2012, 29, 752-779
DOI: 10.1039/C2NP20005H

Assessing calcareous sponges and their associated bacteria for the discovery of new bioactive natural products
Mélanie Roué, Elodie Quévrain, Isabelle Domart-Coulon and Marie-Lise Bourguet-Kondracki
Nat. Prod. Rep., 2012, 29, 739-751
DOI: 10.1039/C2NP20040F

Marine natural products
John W. Blunt, Brent R. Copp, Robert A. Keyzers, Murray H. G. Munro and Michèle R. Prinsep
Nat. Prod. Rep., 2012, 29, 144-222
DOI: 10.1039/C2NP00090C

Strained cyclophane natural products: Macrocyclization at its limits
Tanja Gulder and Phil S. Baran
Nat. Prod. Rep., 2012, 29, 899-934
DOI: 10.1039/C2NP20034A

Natural products from Cephalotaxus sp.: chemical diversity and synthetic aspects
Hajer Abdelkafi and Bastien Nay
Nat. Prod. Rep., 2012, 29, 845-869
DOI: 10.1039/C2NP20037F

Triterpenoids
Robert A. Hill and Joseph D. Connolly
Nat. Prod. Rep., 2012, 29, 780-818
DOI: 10.1039/C2NP20027A

Hypervalent iodine reagents in the total synthesis of natural products
Luiz F. Silva, Jr. and Berit Olofsson
Nat. Prod. Rep., 2011, 28, 1722-1754
DOI: 10.1039/C1NP00028D

Electrophilic natural products and their biological targets
Malte Gersch, Johannes Kreuzer and Stephan A. Sieber
Nat. Prod. Rep., 2012, 29, 659-682
DOI: 10.1039/C2NP20012K

Diterpenoids of terrestrial origin
James R. Hanson
Nat. Prod. Rep., 2012, 29, 890-898
DOI: 10.1039/C2NP20051A

Recent discovery of plant-derived anti-diabetic natural products
Hsin-Yi Hung, Keduo Qian, Susan L. Morris-Natschke, Chau-Shin Hsu and Kuo-Hsiung Lee
Nat. Prod. Rep., 2012, 29, 580-606
DOI: 10.1039/C2NP00074A

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Natural Product Reports? Then why not submit to us today or alternatively email us your suggestions.

This month sees the following articles in Natural Product Reports that are in the top ten most accessed:

Hot off the press
Robert A. Hill and Andrew Sutherland
Nat. Prod. Rep., 2012, 29, 617-621
DOI: 10.1039/C2NP90016E

Bacterial volatiles: the smell of small organisms
Stefan Schulz and Jeroen S. Dickschat
Nat. Prod. Rep., 2007, 24, 814-842
DOI: 10.1039/B507392H

The early stages of taxol biosynthesis: An interim report on the synthesis and identification of early pathway metabolites
Jennifer Guerra-Bubb, Rodney Croteau and Robert M. Williams
Nat. Prod. Rep., 2012, 29, 683-696
DOI: 10.1039/C2NP20021J

Electrophilic natural products and their biological targets
Malte Gersch, Johannes Kreuzer and Stephan A. Sieber
Nat. Prod. Rep., 2012, 29, 659-682
DOI: 10.1039/C2NP20012K

Marine natural products
John W. Blunt, Brent R. Copp, Robert A. Keyzers, Murray H. G. Munro and Michèle R. Prinsep
Nat. Prod. Rep., 2012, 29, 144-222
DOI: 10.1039/C2NP00090C

Triterpenoids
Robert A. Hill and Joseph D. Connolly
Nat. Prod. Rep., 2012, 29, 780-818
DOI: 10.1039/C2NP20027A

Recent discovery of plant-derived anti-diabetic natural products
Hsin-Yi Hung, Keduo Qian, Susan L. Morris-Natschke, Chau-Shin Hsu and Kuo-Hsiung Lee
Nat. Prod. Rep., 2012, 29, 580-606
DOI: 10.1039/C2NP00074A

Pheromones, attractants and other chemical cues of aquatic organisms and amphibians
Scott F. Cummins and John H. Bowie
Nat. Prod. Rep., 2012, 29, 642-658
DOI: 10.1039/C2NP00102K

The taxonomy, biology and chemistry of the fungal Pestalotiopsis genus
Xiao-Long Yang, Jing-Ze Zhang and Du-Qiang Luo
Nat. Prod. Rep., 2012, 29, 622-641
DOI: 10.1039/C2NP00073C

The isoprenoid-precursor dependence of Plasmodium spp.
Jan-Ytzen van der Meer and Anna K. H. Hirsch
Nat. Prod. Rep., 2012, 29, 721-728
DOI: 10.1039/C2NP20013A

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Natural Product Reports? Then why not submit to us today or alternatively email us your suggestions.

This month sees the following articles in Natural Product Reports that are in the top ten most accessed:

Recent discovery of plant-derived anti-diabetic natural products
Hsin-Yi Hung, Keduo Qian, Susan L. Morris-Natschke, Chau-Shin Hsu and Kuo-Hsiung Lee
Nat. Prod. Rep., 2012, 29, 580-606
DOI: 10.1039/C2NP00074A

Marine natural products
John W. Blunt, Brent R. Copp, Robert A. Keyzers, Murray H. G. Munro and Michèle R. Prinsep
Nat. Prod. Rep., 2012, 29, 144-222
DOI: 10.1039/C2NP00090C

NMR in natural products: understanding conformation, configuration and receptor interactions
Teresa Carlomagno
Nat. Prod. Rep., 2012, 29, 536-554
DOI: 10.1039/C2NP00098A

Cytotoxic and antioxidant marine prenylated quinones and hydroquinones
Suthananda N. Sunassee and Michael T. Davies-Coleman
Nat. Prod. Rep., 2012, 29, 513-535
DOI: 10.1039/C2NP00086E

Electrophilic natural products and their biological targets
Malte Gersch, Johannes Kreuzer and Stephan A. Sieber
Nat. Prod. Rep., 2012, 29, 659-682
DOI: 10.1039/C2NP20012K

Pheromones, attractants and other chemical cues of aquatic organisms and amphibians
Scott F. Cummins and John H. Bowie
Nat. Prod. Rep., 2012, 29, 642-658
DOI: 10.1039/C2NP00102K

Hot off the press
Robert A. Hill and Andrew Sutherland
Nat. Prod. Rep., 2012, 29, 435-439
DOI: 10.1039/C2NP90008D

Insights from the sea: Structural biology of marine polyketide synthases
David L. Akey, Jennifer J. Gehret, Dheeraj Khare and Janet L. Smith
Nat. Prod. Rep., 2012, Advance Article
DOI: 10.1039/C2NP20016C

The taxonomy, biology and chemistry of the fungal Pestalotiopsis genus
Xiao-Long Yang, Jing-Ze Zhang and Du-Qiang Luo
Nat. Prod. Rep., 2012, 29, 622-641
DOI: 10.1039/C2NP00073C

Pathways for degradation of lignin in bacteria and fungi
Timothy D. H. Bugg, Mark Ahmad, Elizabeth M. Hardiman and Rahman Rahmanpour
Nat. Prod. Rep., 2011, 28, 1883-1896
DOI: 10.1039/C1NP00042J

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Natural Product Reports? Then why not submit to us today or alternatively email us your suggestions.

This month sees the following articles in Natural Product Reports that are in the top ten most accessed:

Hot off the press
Robert A. Hill and Andrew Sutherland
Nat. Prod. Rep., 2012, 29, 435-439
DOI: 10.1039/C2NP90008D

Marine natural products
John W. Blunt, Brent R. Copp, Robert A. Keyzers, Murray H. G. Munro and Michèle R. Prinsep
Nat. Prod. Rep., 2012, 29, 144-222
DOI: 10.1039/C2NP00090C

Cytotoxic and antioxidant marine prenylated quinones and hydroquinones
Suthananda N. Sunassee and Michael T. Davies-Coleman
Nat. Prod. Rep., 2012, 29, 513-535
DOI: 10.1039/C2NP00086E

Triptolide: structural modifications, structure–activity relationships, bioactivities, clinical development and mechanisms
Zhao-Li Zhou, Ya-Xi Yang, Jian Ding, Yuan-Chao Li and Ze-Hong Miao
Nat. Prod. Rep., 2012, 29, 457-475
DOI: 10.1039/C2NP00088A

Phenazines and cancer
A. Cimmino, A. Evidente, V. Mathieu, A. Andolfi, F. Lefranc, A. Kornienko and R. Kiss
Nat. Prod. Rep., 2012, 29, 487-501
DOI: 10.1039/C2NP00079B

Key achievements in the total synthesis of vibsane-type diterpenoids
Jeffrey Y. W. Mak and Craig M. Williams
Nat. Prod. Rep., 2012, 29, 440-448
DOI: 10.1039/C2NP00067A

Natural products as kinase inhibitors
Jing Liu, Yi Hu, David L. Waller, Junfeng Wang and Qingsong Liu
Nat. Prod. Rep., 2012, 29, 392-403
DOI: 10.1039/C2NP00097K

Advances in Aspergillus secondary metabolite research in the post-genomic era
James F. Sanchez, Amber D. Somoza, Nancy P. Keller and Clay C. C. Wang
Nat. Prod. Rep., 2012, 29, 351-371
DOI: 10.1039/C2NP00084A

Pathways for degradation of lignin in bacteria and fungi
Timothy D. H. Bugg, Mark Ahmad, Elizabeth M. Hardiman and Rahman Rahmanpour
Nat. Prod. Rep., 2011, 28, 1883-1896
DOI: 10.1039/C1NP00042J

Peptidoglycan as Nod1 ligand; fragment structures in the environment, chemical synthesis, and their innate immunostimulation
Yukari Fujimoto, Ambara Rachmat Pradipta, Naohiro Inohara and Koichi Fukase
Nat. Prod. Rep., 2012, 29, 568-579
DOI: 10.1039/C2NP00091A

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Natural Product Reports? Then why not submit to us today or alternatively email us your suggestions.

This month sees the following articles in Natural Product Reports that are in the top ten most accessed:

Marine natural products
John W. Blunt, Brent R. Copp, Robert A. Keyzers, Murray H. G. Munro and Michèle R. Prinsep
Nat. Prod. Rep., 2012, 29, 144-222
DOI: 10.1039/C2NP00090C

Hot off the press
Robert A. Hill and Andrew Sutherland
Nat. Prod. Rep., 2012, 29, 129-133
DOI: 10.1039/C1NP90052H

Advances in Aspergillus secondary metabolite research in the post-genomic era
James F. Sanchez, Amber D. Somoza, Nancy P. Keller and Clay C. C. Wang
Nat. Prod. Rep., 2012, 29, 351-371
DOI: 10.1039/C2NP00084A

Natural products as kinase inhibitors
Jing Liu, Yi Hu, David L. Waller, Junfeng Wang and Qingsong Liu
Nat. Prod. Rep., 2012, 29, 392-403
DOI: 10.1039/C2NP00097K

The chemical ecology of cyanobacteria
Pedro N. Leão, Niclas Engene, Agostinho Antunes, William H. Gerwick and Vitor Vasconcelos
Nat. Prod. Rep., 2012, 29, 372-391
DOI: 10.1039/C2NP00075J

Angucyclines: Biosynthesis, mode-of-action, new natural products, and synthesis
Madan K. Kharel, Pallab Pahari, Micah D. Shepherd, Nidhi Tibrewal, S. Eric Nybo, Khaled A. Shaaban and Jürgen Rohr
Nat. Prod. Rep., 2012, 29, 264-365
DOI: 10.1039/C1NP00068C

Biosynthesis of 3,5-AHBA-derived natural products
Qianjin Kang, Yuemao Shen and Linquan Bai
Nat. Prod. Rep., 2012, 29, 243-263
DOI: 10.1039/C2NP00019A

The taxonomy, biology and chemistry of the fungal Pestalotiopsis genus
Xiao-Long Yang, Jing-Ze Zhang and Du-Qiang Luo
Nat. Prod. Rep., 2012, Advance Article
DOI: 10.1039/C2NP00073C

Marine natural products
John W. Blunt, Brent R. Copp, Murray H. G. Munro, Peter T. Northcote and Michèle R. Prinsep
Nat. Prod. Rep., 2011, 28, 196-268
DOI: 10.1039/C005001F

Influenza neuraminidase: A druggable target for natural products
Ulrike Grienke, Michaela Schmidtke, Susanne von Grafenstein, Johannes Kirchmair, Klaus R. Liedl and Judith M. Rollinger
Nat. Prod. Rep., 2012, 29, 11-36
DOI: 10.1039/C1NP00053E

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Natural Product Reports? Then why not submit to us today or alternatively email us your suggestions.

This month sees the following articles in Natural Product Reports that are in the top ten most accessed:

Marine natural products
John W. Blunt, Brent R. Copp, Robert A. Keyzers, Murray H. G. Munro and Michèle R. Prinsep
Nat. Prod. Rep., 2012, 29, 144-222
DOI: 10.1039/C2NP00090C

Influenza neuraminidase: A druggable target for natural products
Ulrike Grienke, Michaela Schmidtke, Susanne von Grafenstein, Johannes Kirchmair, Klaus R. Liedl and Judith M. Rollinger
Nat. Prod. Rep., 2012, 29, 11-36
DOI: 10.1039/C1NP00053E

Beyond ethylmalonyl-CoA: The functional role of crotonyl-CoA carboxylase/reductase homologs in expanding polyketide diversity
Micheal C. Wilson and Bradley S. Moore
Nat. Prod. Rep., 2012, 29, 72-86
DOI: 10.1039/C1NP00082A

Marine natural products
John W. Blunt, Brent R. Copp, Murray H. G. Munro, Peter T. Northcote and Michèle R. Prinsep
Nat. Prod. Rep., 2011, 28, 196-268
DOI: 10.1039/C005001F

Sesquiterpene synthases: Passive catalysts or active players?
David J. Miller and Rudolf K. Allemann
Nat. Prod. Rep., 2012, 29, 60-71
DOI: 10.1039/C1NP00060H

Aminobenzoates as building blocks for natural product assembly lines
Christopher T. Walsh, Stuart W. Haynes and Brian D. Ames
Nat. Prod. Rep., 2012, 29, 37-59
DOI: 10.1039/C1NP00072A

Hot off the press
Robert A. Hill and Andrew Sutherland
Nat. Prod. Rep., 2011, 28, 1879-1882
DOI: 10.1039/C1NP90043A

The diazofluorene antitumor antibiotics: Structural elucidation, biosynthetic, synthetic, and chemical biological studies
Seth B. Herzon and Christina M. Woo
Nat. Prod. Rep., 2012, 29, 87-118
DOI: 10.1039/C1NP00052G

Macrocylic bisbibenzyl natural products and their chemical synthesis
David C. Harrowven and Sarah L. Kostiuk
Nat. Prod. Rep., 2012, 29, 223-242
DOI: 10.1039/C1NP00080B

Pathways for degradation of lignin in bacteria and fungi
Timothy D. H. Bugg, Mark Ahmad, Elizabeth M. Hardiman and Rahman Rahmanpour
Nat. Prod. Rep., 2011, 28, 1883-1896
DOI: 10.1039/C1NP00042J

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Natural Product Reports? Then why not submit to us today or alternatively email us your suggestions.

This month sees the following articles in Natural Product Reports that are in the top ten most accessed:

Hot off the press
Robert A. Hill and Andrew Sutherland
Nat. Prod. Rep., 2011, 28, 1879-1882
DOI: 10.1039/C1NP90043A

Pathways for degradation of lignin in bacteria and fungi
Timothy D. H. Bugg, Mark Ahmad, Elizabeth M. Hardiman and Rahman Rahmanpour
Nat. Prod. Rep., 2011, 28, 1883-1896
DOI: 10.1039/C1NP00042J

Aminobenzoates as building blocks for natural product assembly lines
Christopher T. Walsh, Stuart W. Haynes and Brian D. Ames
Nat. Prod. Rep., 2012, 29, 37-59
DOI: 10.1039/C1NP00072A

Marine natural products
John W. Blunt, Brent R. Copp, Murray H. G. Munro, Peter T. Northcote and Michèle R. Prinsep
Nat. Prod. Rep., 2011, 28, 196-268
DOI: 10.1039/C005001F

Natural products and Pharma 2011: Strategic changes spur new opportunities
Guy T. Carter
Nat. Prod. Rep., 2011, 28, 1783-1789
DOI: 10.1039/C1NP00033K

Isoprenoids in three-dimensional space: the stereochemistry of terpene biosynthesis
Jeroen S. Dickschat
Nat. Prod. Rep., 2011, 28, 1917-1936
DOI: 10.1039/C1NP00063B

Sesquiterpene synthases: Passive catalysts or active players?
David J. Miller and Rudolf K. Allemann
Nat. Prod. Rep., 2012, 29, 60-71
DOI: 10.1039/C1NP00060H

The diazofluorene antitumor antibiotics: Structural elucidation, biosynthetic, synthetic, and chemical biological studies
Seth B. Herzon and Christina M. Woo
Nat. Prod. Rep., 2012, 29, 87-118
DOI: 10.1039/C1NP00052G

Multitargeting by curcumin as revealed by molecular interaction studies
Subash C. Gupta, Sahdeo Prasad, Ji Hye Kim, Sridevi Patchva, Lauren J. Webb, Indira K. Priyadarsini and Bharat B. Aggarwal
Nat. Prod. Rep., 2011, 28, 1937-1955
DOI: 10.1039/C1NP00051A

Influenza neuraminidase: A druggable target for natural products
Ulrike Grienke, Michaela Schmidtke, Susanne von Grafenstein, Johannes Kirchmair, Klaus R. Liedl and Judith M. Rollinger
Nat. Prod. Rep., 2012, 29, 11-36
DOI: 10.1039/C1NP00053E

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Natural Product Reports? Then why not submit to us today or alternatively email us your suggestions.

This month sees the following articles in Natural Product Reports that are in the top ten most accessed:

Natural products and Pharma 2011: Strategic changes spur new opportunities
Guy T. Carter
Nat. Prod. Rep., 2011, 28, 1783-1789
DOI: 10.1039/C1NP00033K

Multitargeting by curcumin as revealed by molecular interaction studies
Subash C. Gupta, Sahdeo Prasad, Ji Hye Kim, Sridevi Patchva, Lauren J. Webb, Indira K. Priyadarsini and Bharat B. Aggarwal
Nat. Prod. Rep., 2011, 28, 1937-1955
DOI: 10.1039/C1NP00051A

Isoprenoids in three-dimensional space: the stereochemistry of terpene biosynthesis
Jeroen S. Dickschat
Nat. Prod. Rep., 2011, 28, 1917-1936
DOI: 10.1039/C1NP00063B

Marine natural products
John W. Blunt, Brent R. Copp, Murray H. G. Munro, Peter T. Northcote and Michèle R. Prinsep
Nat. Prod. Rep., 2011, 28, 196-268
DOI: 10.1039/C005001F

The sorbicillinoid family of natural products: Isolation, biosynthesis, and synthetic studies
Andrew M. Harned and Kelly A. Volp
Nat. Prod. Rep., 2011, 28, 1790-1810
DOI: 10.1039/C1NP00039J

Hot off the Press
Robert A. Hill and Andrew Sutherland
Nat. Prod. Rep., 2011, 28, 1621-1625
DOI: 10.1039/C1NP90035H

Hypervalent iodine reagents in the total synthesis of natural products
Luiz F. Silva, Jr. and Berit Olofsson
Nat. Prod. Rep., 2011, 28, 1722-1754
DOI: 10.1039/C1NP00028D

Combinatorial biosynthesis in plants: A (p)review on its potential and future exploitation
Jacob Pollier, Tessa Moses and Alain Goossens
Nat. Prod. Rep., 2011, 28, 1897-1916
DOI: 10.1039/C1NP00049G

Hot off the Press
Robert A. Hill and Andrew Sutherland
Nat. Prod. Rep., 2011, 28, 1879-1882
DOI: 10.1039/C1NP90043A

The regulation of the secondary metabolism of Streptomyces: new links and experimental advances
Gilles P. van Wezel and Kenneth J. McDowall
Nat. Prod. Rep., 2011, 28, 1311-1333
DOI: 10.1039/C1NP00003A

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Natural Product Reports? Then why not submit to us today or alternatively email us your suggestions.