Natural Products Blog

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Total synthesis of (+)-herboxidiene/GEX 1A
Alejandro Gómez-Palomino, Miquel Pellicena, Katrina Krämer, Pedro Romea, Fèlix Urpí, Gabriel Aullón and José M. Padrón
DOI: 10.1039/C7OB00072C, Paper

First asymmetric total synthesis of aspergillide D
Bighnanshu K. Jena, G. Sudhakar Reddy and Debendra K. Mohapatra
DOI: 10.1039/C6OB02435A, Paper

Torsional steering as friend and foe: development of a synthetic route to the briarane diterpenoid stereotetrad
Nicholas G. Moon and Andrew M. Harned  
DOI: 10.1039/C7OB00124J, Paper

Computational studies on the cyclization of squalene to the steroids and hopenes
B. Andes Hess
DOI: 10.1039/C7OB00222J, Review Article

Isoafricanol synthase from Streptomyces malaysiensis
Patrick Rabe, Markiyan Samborskyy, Peter F. Leadlay and Jeroen S. Dickschat  
DOI: 10.1039/C7OB00234C, Communication

An efficient Ugi-3CR/aza Diels–Alder/Pomeranz–Fritsch protocol towards novel aza-analogues of (±)-nuevamine, (±)-lennoxamine and magallanesine: a diversity oriented synthesis approach
Óscar Vázquez-Vera, Jorge S. Sánchez-Badillo, Alejandro Islas-Jácome, Manuel A. Rentería-Gómez, Shrikant G. Pharande, Carlos J. Cortes-García, Mónica A. Rincón-Guevara, Ilich A. Ibarra, Rocío Gámez-Montaño and Eduardo González-Zamora  
DOI: 10.1039/C6OB02572B, Paper

Intramolecular macrolactonization, photophysical and biological studies of new class of polycyclic pyrrole derivatives
Suresh Kumar Mondal, Arabinda Mandal, Susanta Kumar Manna, Sk Asraf Ali, Maidul Hossain, Vangala Venugopal, Avijit Jana and Shubhankar Samanta  
DOI: 110.1039/C7OB00160F, Paper

Isolation and structure elucidation of natural products of three soft corals and a sponge from the coast of Madagascar
Marie Pascaline Rahelivao, Tilo Lübken, Margit Gruner, Olga Kataeva, Rahanira Ralambondrahety, Hanta Andriamanantoanina, Marek P. Checinski, Ingmar Bauer and Hans-Joachim Knölker  
DOI: 10.1039/C7OB00191F, Paper

Total synthesis of phenylpropanoid glycoside osmanthuside-B6 facilitated by double isomerisation of glucose–rhamnose orthoesters
Duc Thinh Khong and Zaher M. A. Judeh  
DOI: 10.1039/C7OB00198C, Paper

Biosynthetic 4,6-dehydratase gene deletion: isolation of a glucosylated jadomycin natural product provides insight into the substrate specificity of glycosyltransferase JadS
S. M. Forget, Jungwook Na, N. E. McCormick and D. L. Jakeman
DOI: 10.1039/C7OB00259A, Communication

Syntheses of C17–C27 fragments of 20-deoxybryostatins for assembly using Julia and metathesis reactions
Matthew Ball, Thomas Gregson, Hiroki Omori and Eric J. Thomas  
DOI: 10.1039/C7OB00076F, Paper

Some limitations of an approach to the assembly of bryostatins by ring-closing metathesis
Raphaël Dumeunier, Thomas Gregson, Somhairle MacCormick, Hiroki Omori and Eric J. Thomas  
DOI: 10.1039/C7OB00079K, Paper

Stereochemical investigations of the Tetrahymena cyclase, a model system for euphane/tirucallane biosynthesis
José-Luis Giner and Ju Feng  
DOI: 10.1039/C7OB00296C, Paper

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Bioinspired total syntheses of terpenoids
Cedric L. Hugelshofer and Thomas Magauer
DOI: 10.1039/C6OB02488B, Perspective

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Total synthesis and confirmation of the revised structures of jiangrines A, C and D
Zhijiang Zhang and Bo Liu
DOI: 10.1039/C6OB02379G, Paper

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Fluorometabolite biosynthesis: isotopically labelled glycerol incorporations into the antibiotic nucleocidin in Streptomyces calvus
Axel Bartholomé, Jeffrey E. Janso, Usa Reilly and David O’Hagan
DOI: 10.1039/C6OB02291J, Communication

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Enantiospecific total syntheses of meroterpenoids (−)-F1839-I and (−)-corallidictyals B and D
Dattatraya H. Dethe, Balu D. Dherange, Saghir Ali and Mahesh M. Parsutkar
DOI: 10.1039/C6OB02322C, Communication

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Second-generation total synthesis of aplyronine A featuring Ni/Cr-mediated coupling reactions
Ichiro Hayakawa, Keita Saito, Sachiko Matsumoto, Shinichi Kobayashi, Ayaka Taniguchi, Kenichi Kobayashi, Yusuke Fujii, Takahiro Kaneko and Hideo Kigoshi
DOI: 10.1039/C6OB02241C, Paper

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The first total synthesis of the marine acetylenic alcohol, lembehyne B – a selective inducer of early apoptosis in leukemia cancer cells
Lilya U. Dzhemileva, Vladimir A. D’yakonov, Aleksey A. Makarov, Evgeny N. Andreev, Milyausha M. Yunusbaeva and Usein M. Dzhemilev  
DOI: 10.1039/C6OB02346K, Paper

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An efficient approach to trans-4-hydroxy-5-substituted 2-pyrrolidinones through a stereoselective tandem Barbier process: divergent syntheses of (3R,4S)-statines, (+)-preussin and (−)-hapalosin
Chang-Mei Si, Lu-Ping Shao, Zhuo-Ya Mao, Wen Zhou and Bang-Guo Wei  
DOI: 10.1039/C6OB02523D, Paper

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A protecting-group-free synthesis of (+)-nephrosteranic, (+)-protolichesterinic, (+)-nephrosterinic, (+)-phaseolinic, (+)-rocellaric acids and (+)-methylenolactocin
Jothi L. Nallasivam and Rodney A. Fernandes
DOI: 10.1039/C6OB02398C, Paper

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Stepwise cyclopropanation on the polycyclopropanated polyketide formation in jawsamycin biosynthesis
Tomoshige Hiratsuka, Hideaki Suzuki, Atsushi Minami and Hideaki Oikawa
DOI: 10.1039/C6OB02675C, Communication

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A novel withanolide with an unprecedented carbon skeleton from Physalis angulata
Cheng-Peng Sun, Andrei G. Kutateladze, Feng Zhao, Li-Xia Chen and Feng Qiu  
DOI: 10.1039/C6OB02656G, Communication

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Total synthesis and biological activity of dolastatin 16
Loida O. Casalme, Arisa Yamauchi, Akinori Sato, Julie G. Petitbois, Yasuyuki Nogata, Erina Yoshimura, Tatsufumi Okino, Taiki Umezawa and Fuyuhiko Matsuda  
DOI: 10.1039/C6OB02657E, Paper

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New compounds from a hydrothermal vent crab-associated fungus Aspergillus versicolor XZ-4
Chengqian Pan, Yutong Shi, Xuegang Chen, Chen-Tung Arthur Chen, Xinyi Tao and Bin Wu  
DOI: 10.1039/C6OB02374F, Paper

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Chemoenzymatic synthesis of unmodified heparin oligosaccharides: cleavage of p-nitrophenyl glucuronide by alkaline and Smith degradation
Xing Zhang, Yongmei Xu, Po-Hung Hsieh, Jian Liu, Lei Lin, Eric P. Schmidt and Robert J. Linhardt  
DOI: 10.1039/C6OB02603F, Paper

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Isoafricanol synthase from Streptomyces malaysiensis
Patrick Rabe, Markiyan Samborskyy, Peter F. Leadlay and Jeroen S. Dickschat  
DOI: 10.1039/C7OB00234C, Communication

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An efficient Ugi-3CR/aza Diels–Alder/Pomeranz–Fritsch protocol towards novel aza-analogues of (±)-nuevamine, (±)-lennoxamine and magallanesine: a diversity oriented synthesis approach
Óscar Vázquez-Vera, Jorge S. Sánchez-Badillo, Alejandro Islas-Jácome, Manuel A. Rentería-Gómez, Shrikant G. Pharande, Carlos J. Cortes-García, Mónica A. Rincón-Guevara, Ilich A. Ibarra, Rocío Gámez-Montaño and Eduardo González-Zamora  
DOI: 10.1039/C6OB02572B, Paper

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Intramolecular macrolactonization, photophysical and biological studies of new class of polycyclic pyrrole derivatives
Suresh Kumar Mondal, Arabinda Mandal, Susanta Kumar Manna, Sk Asraf Ali, Maidul Hossain, Vangala Venugopal, Avijit Jana and Shubhankar Samanta  
DOI: 10.1039/C7OB00160F, Paper

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Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Gold catalysis: synthesis of spiro, bridged, and fused ketal natural products
Rachelle Quach, Daniel P. Furkert and Margaret A. Brimble  
DOI: 10.1039/C7OB00496F, Review Article

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Application of the aza-Diels–Alder reaction in the synthesis of natural products
Min-Hui Cao, Nicholas J. Green and Sheng-Zhen Xu  
DOI: 10.1039/C6OB02761J, Review Article

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ipso-Cyclization: an emerging tool for multifunctional spirocyclohexadienones
Chada Raji Reddy, Santosh Kumar Prajapti, Kamalkishor Warudikar, Ravi Ranjan and Billa Bhargava Rao  
DOI: 10.1039/C7OB00405B, Review Article

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cis or trans with class II diterpene cyclases
Meirong Jia and Reuben J. Peters  
DOI: 10.1039/C7OB00510E, Communication

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Enantioselective Diels-Alder-lactamization organocascades employing a furan-based diene
Mikail E. Abbasov, Brandi M. Hudson, Weixu Kong, Dean J. Tantillo and Daniel Romo  
DOI: 10.1039/C6OB02738E, Communication

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Synthesis, SAR and biological studies of sugar amino acid-based almiramide analogues: N-methylation leads the way
Dipendu Das, Hina P. A. Khan, Rahul Shivahare, Suman Gupta, Jayanta Sarkar, Mohd. Imran Siddiqui, Ravi Sankar Ampapathi and Tushar Kanti Chakraborty  
DOI: 10.1039/C6OB02610A, Paper

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JA-Ile-macrolactones uncouple growth and defense in wild tobacco
Guillermo H. Jimenez-Aleman, Ricardo A. R. Machado, Ian T. Baldwin and Wilhelm Boland  
DOI: 10.1039/C7OB00249A, Communication

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Enantioselective total synthesis of (+)-arborescidine C and related tetracyclic indole alkaloids using organocatalysis
Vishal M. Sheth, Bor-Cherng Hong and Gene-Hsiang Lee  
DOI: 10.1039/C7OB00473G, Communication

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Synthesis of AHMOD-containing aminolipopeptides, unique bioactive peptaibiotics
Louise A. Stubbing, Iman Kavianinia and Margaret A. Brimble  
DOI: 10.1039/C7OB00541E, Review Article

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Enantioselective total synthesis of colomitides and their absolute configuration determination and structural revision
Hongguang Yang, Xiaoyu Liu, Xiaoyu Li, Xiang Shi, Feilong Yang, Xiaozhen Jiao and Ping Xie  
DOI: 10.1039/C7OB00539C, Paper

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Biochemical studies of inositol N-acetylglucosaminyltransferase involved in mycothiol biosynthesis in Corynebacterium diphtheria
Yuchuan Guo, Lizhen Wang, Jiatong Guo, Guofeng Gu and Zhongwu Guo  
DOI: 10.1039/C7OB00555E, Paper

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Dissection of the neocarazostatin: a C4 alkyl side chain biosynthesis by in vitro reconstitution
Li Su, Rui Zhang, Kwaku Kyeremeh, Zixin Deng, Hai Deng and Yi Yu  
DOI: 10.1039/C7OB00617A, Communication

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Rifamorpholines A–E, potential antibiotics from locust-associated actinobacteria Amycolatopsis sp. Hca4
Yong Sheng Xiao, Bo Zhang, Mei Zhang, Zhi Kai Guo, Xin Zhao Deng, Jing Shi, Wei Li, Rui Hua Jiao, Ren Xiang Tan and Hui Ming Ge  
DOI: 10.1039/C7OB00614D, Paper

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Asymmetric synthesis of ent-fragransin C1
Santikorn Chaimanee, Manat Pohmakotr, Chutima Kuhakarn, Vichai Reutrakul and Darunee Soorukram  
DOI: 10.1039/C7OB00749C, Paper

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Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Total synthesis based on the originally claimed structure of mucosin
Harrison C. Gallantree-Smith, Simen G. Antonsen, Carl H. Görbitz, Trond V. Hansen, Jens M. J. Nolsøe and Yngve H. Stenstrøm
DOI: 10.1039/C6OB01511E, Communication

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Synthesis and biological evaluation of palmyrolide A macrocycles as sodium channel blockers towards neuroprotection
Satish Chandra Philkhana, Suneet Mehrotra, Thomas F. Murray and D. Srinivasa Reddy
DOI: 10.1039/C6OB01372D, Paper

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Microwave assisted synthesis of phenanthridinones and dihydrophenanthridines by vasicine/KOtBu promoted intramolecular C–H arylation
Sushila Sharma, Manoranjan Kumar, Shruti Sharma, Onkar S. Nayal, Neeraj Kumar, Bikram Singh and Upendra Sharma
DOI: 10.1039/C6OB01362G, Paper

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Effective one-pot multienzyme (OPME) synthesis of monotreme milk oligosaccharides and other sialosides containing 4-O-acetyl sialic acid
Hai Yu, Jie Zeng, Yanhong Li, Vireak Thon, Baojun Shi and Xi Chen
DOI: 10.1039/C6OB01706A, Paper

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Chemoselective photooxygenations of furans bearing unprotected amines: their use in alkaloid synthesis
T. Montagnon, D. Kalaitzakis, M. Sofiadis and G. Vassilikogiannakis
DOI: 10.1039/C6OB01689H, Perspective

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A protecting group-free synthesis of (−)-hortonones A–C from the Inhoffen–Lythgoe diol
Hovsep Stambulyan and Thomas G. Minehan
DOI: 10.1039/C6OB01738J, Paper

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Total synthesis of cananginone C and structural revision of debilisone A
Tapan Kumar Kuilya and Rajib Kumar Goswami
DOI: 10.1039/C6OB01671E, Paper

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Total synthesis of mangiferin, homomangiferin, and neomangiferin
Xiong Wei, Danlin Liang, Qing Wang, Xiangbao Meng and Zhongjun Li
DOI: 10.1039/C6OB01622G, Paper

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Substitution dependent stereoselective construction of bicyclic lactones and its application to the total synthesis of pyranopyran, tetraketide and polyrhacitide A
B. V. Subba Reddy, Dhanraj O. Biradar, Y. Vikram Reddy, J. S. Yadav, Kiran Kumar Singarapu and B. Sridhar
DOI: 10.1039/C6OB01686C, Paper

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4,4′-Bismoschamine: biomimetic synthesis and evidence to support structural equivalency to montamine
Kaitlin G. Henry, Lachlan M. Blair, Jonathan Sperry and Elizabeth A. Colby Davie
DOI: 10.1039/C6OB01685E, Paper

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Total synthesis of diptoindonesin G and its analogues as selective modulators of estrogen receptors
Ji-tian Liu, Truman J. Do, Christopher J. Simmons, John C. Lynch, Wen Gu, Zhi-Xiong Ma, Wei Xu and Weiping Tang
DOI: 10.1039/C6OB01657J, Communication

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Phosphorylated cyclopropanes in the synthesis of α-alkylidene-γ-butyrolactones: total synthesis of (±)-savinin, (±)-gadain and (±)-peperomin E
Matthew G. Lloyd, Richard J. K. Taylor and William P. Unsworth
DOI: 10.1039/C6OB01527A, Paper

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De novo protecting-group-free total synthesis of (+)-muricadienin, (+)-ancepsenolide and (+)-3-hexadecyl-5-methylfuran-2(5H)-one
Rupesh A. Kunkalkar, Debasish Laha and Rodney A. Fernandes
DOI: 10.1039/C6OB01721E, Paper

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An expeditious synthesis of the ascomycete metabolite rigidiusculamide B
Anja Wunder and Rainer Schobert
DOI: 10.1039/C6OB01836J, Paper

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Total synthesis of haliclamide
Suraksha Gahalawat and Satyendra Kumar Pandey
DOI: 10.1039/C6OB01775D, Paper

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Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Preparation of oxocene terpenes. The first enantiospecific synthesis of cytotoxic arenaran A
Alejandro Torres, Pilar Gutierrez, Ramón Alvarez-Manzaneda, Rachid Chahboun and Enrique Alvarez-Manzaneda
DOI: 10.1039/C6OB01640E, Paper

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Synthesis of crinane utilizing an allylic sulfoxide for the construction of a hydroindole ring via vinylogous C–N bond formation
Sadagopan Raghavan and Anil Ravi
DOI: 10.1039/C6OB01966H, Paper

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Total synthesis of wewakazole B
Bohua Long, Jingzhao Zhang, Xudong Tang and Zhengzhi Wu
DOI: 10.1039/C6OB01783E, Communication

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Total synthesis of (±)-ganocins B and C
Yao Liu, Chu-Jun Zhou, Qingjiang Li and Honggen Wang
DOI: 10.1039/C6OB02049F, Communication

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Stereoselective synthesis of (−)-desethyleburnamonine, (−)-vindeburnol and (−)-3-epitacamonine: observation of a substrate dependent diastereoselectivity reversal of an aldol reaction
Pravat Mondal and Narshinha P. Argade
DOI: 10.1039/C6OB01438K, Paper

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Stereoselective construction of 2-vinyl 3-hydroxybenzopyran rings: total syntheses of teadenols A and B
Ryunosuke Yoshida, Hitoshi Ouchi, Atsushi Yoshida, Tomohiro Asakawa, Makoto Inai, Masahiro Egi, Yoshitaka Hamashima and Toshiyuki Kan
DOI: 10.1039/C6OB02004F, Communication

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Total synthesis, structural elucidation and anti-inflammatory activity evaluation of 2-deoxy-3,6-anhydro hexofuranoside derivatives isolated from Sauropus rostratus
Chenxi Zhang, Chengcheng Wang, Zihao Wang, Genzoh Tanabe, Osamu Muraoka, Aijun Lin, Jinyi Xu, Xiaoming Wu, Liang Wu and Weijia Xie
DOI: 10.1039/C6OB02207C, Paper

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SCascade oxime formation, cyclization to a nitrone, and intermolecular dipolar cycloaddition
Rachel C. Furnival, Rungroj Saruengkhanphasit, Heather E. Holberry, Jonathan R. Shewring, Hélène D. S. Guerrand, Harry Adams and Iain Coldham
DOI: 10.1039/C6OB01871H, Paper

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Synthetic analogs of stryphnusin isolated from the marine sponge Stryphnus fortis inhibit acetylcholinesterase with no effect on muscle function or neuromuscular transmission
Lindon W. K. Moodie, Monika C. Žužek, Robert Frangež, Jeanette H. Andersen, Espen Hansen, Elisabeth K. Olsen, Marija Cergolj, Kristina Sepčić, Kine Ø. Hansen and Johan Svenson
DOI: 10.1039/C6OB02120D, Paper

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Macrolactam analogues of macrolide natural products
Helmut M. Hügel, Andrew T. Smith and Mark A. Rizzacasa
DOI: 10.1039/C6OB02149B, Review Article

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Enantioselective total synthesis and structural assignment of callyspongiolide
Arun K. Ghosh, Luke A. Kassekert and Joseph D. Bungard
DOI: 10.1039/C6OB02051H, Paper

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Total synthesis of natural derivatives and artificial analogs of 13-oxyingenol and their biological evaluation
Takayuki Ohyoshi, Yuki Tamura, Ichiro Hayakawa, Go Hirai, Yamato Miyazawa, Shota Funakubo, Mikiko Sodeoka and Hideo Kigoshi
DOI: 10.1039/C6OB02268E, Paper

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Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Asymmetric synthesis and absolute stereochemistry of a labdane-type diterpenoid isolated from the rhizomes of Isodan yuennanensis
Heping Deng, Wei Cao, Zhijiang Zhang and Bo Liu
DOI: 10.1039/C6OB00750C, Paper

Biosynthesis of isoxazolin-5-one and 3-nitropropanoic acid containing glucosides in juvenile Chrysomelina
Tobias Becker, Kerstin Ploss and Wilhelm Boland
DOI: 10.1039/C6OB00899B, Paper

Overproduction and identification of butyrolactones SCB1–8 in the antibiotic production superhost Streptomyces M1152
John D. Sidda, Vincent Poon, Lijiang Song, Weishan Wang, Keqian Yang and Christophe Corre
DOI: 10.1039/C6OB00840B, Communication

Synthesis and biological evaluation of acylated oligorhamnoside derivatives structurally related to mezzettiaside-6 with cytotoxic activity
Gaopeng Song, Sumei Li, Zhiwei Lei, Yibin Li, Junhua Li, Yixian Liao and Zi-Ning Cui
DOI: 10.1039/C6OB00862C, Paper

Asymmetric synthesis of (+)-17-epi-methoxy-kauran-3-one through tandem oxidative polycyclization-pinacol process
Gaëtan Maertens, Samuel Desjardins and Sylvain Canesi
DOI: 10.1039/C6OB01142J, Paper

Enantioselective synthesis of (+)-brevipolide H
Ching-Nung Chen and Duen-Ren Hou
DOI: 10.1039/C6OB01071G, Paper

Synthetic studies of callyspongiolide: synthesis of the macrolactone core of the molecule
Sudhakar Athe, Ashish Sharma, Kanakaraju Marumudi and Subhash Ghosh
DOI: 10.1039/C6OB01007E, Paper

Synthesis of L-indospicine, [5,5,6-²H₃]-L-indospicine and L-norindospicine
Cheng-Shan Lang, Siew-Hoon Wong, Sharon Chow, Victoria L. Challinor, Ken W. L. Yong, Mary T. Fletcher, Dionne M. Arthur, Jack C. Ng and James J. De Voss
DOI: 10.1039/C6OB01187J, Paper

Synthesis of 2,6-trans– and 3,3,6-trisubstituted tetrahydropyran-4-ones from Maitland–Japp derived 2H-dihydropyran-4-ones: a total synthesis of diospongin B
Paul A. Clarke, Nadiah Mad Nasir, Philip B. Sellars, Alejandra M. Peter, Connor A. Lawson and James L. Burroughs
DOI: 10.1039/C6OB01182A, Paper

Catalytic asymmetric reactions and synthesis of quinones
Basavaprabhu Hosamani, Matheus F. Ribeiro, Eufrânio N. da Silva Júnior and Irishi N. N. Namboothiri
DOI: 10.1039/C6OB01119E, Review Article

Platinum-catalyzed cycloisomerizations of a common enyne: a divergent entry to cyclopropane sesquiterpenoids. Formal synthesis of sarcandralactone A
Vera P. Demertzidou and Alexandros L. Zografos
DOI: 10.1039/C6OB011226D, Communication

Synthesis of the 2-formylpyrrole spiroketal pollenopyrroside A and structural elucidation of xylapyrroside A, shensongine A and capparisine BA
James M. Wood, Daniel P. Furkert and Margaret A. Brimble
DOI: 10.1039/C6OB01361A, Paper

Biosynthesis-driven structure–activity relationship study of premonensin-derivatives A
A. Ismail-Ali, E. K. Fansa, N. Pryk, S. Yahiaoui, S. Kushnir, M. Pflieger, A. Wittinghofer and F. Schulz
DOI: 10.1039/C6OB01201A, Paper

Horner–Wadsworth–Emmons approach to piperlongumine analogues with potent anti-cancer activity
Li-Chen Han, Paul A. Stanley, Paul J. Wood, Pallavi Sharma, Anchala I. Kuruppu, Tracey D. Bradshaw and John E. Moses
DOI: 10.1039/C6OB01160H, Paper

We hope you enjoy this selection!
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