Natural Products Blog

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although your best bet is for you to sign up to OBC’s e-alert (free service), and receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Total synthesis of alkyl citrate natural products
Mark A. Rizzacasa and Dayna Sturgess
Org. Biomol. Chem., 2014,12, 1367-1382
DOI: 10.1039/C3OB42231C, Review Article; Download PDF

Callyspongisines A–D: bromopyrrole alkaloids from an Australian marine sponge, Callyspongia sp.
Fabien Plisson, Pritesh Prasad, Xue Xiao, Andrew M. Piggott, Xiao-cong Huang, Zeinab Khalil and Robert J. Capon
Org. Biomol. Chem., 2014,12, 1579-1584
DOI: 10.1039/C4OB00091A, Paper; Download PDF

A rapid and efficient access to renieramycin-type alkaloids featuring a temperature-dependent stereoselective cyclization
Hao Liu, Ruijiao Chen and Xiaochuan Chen
Org. Biomol. Chem., 2014,12, 1633-1640
DOI: 10.1039/C3OB42209G, Paper; Download PDF

Chemical synthesis of staphyloferrin A and its application for Staphylococcus aureus detection
Rajesh K. Pandey, Gregory G. Jarvis and Philip S. Low
Org. Biomol. Chem., 2014,12, 1707-1710
DOI: 10.1039/C3OB41230J, Communication; Download PDF

Towards the diastereoselective synthesis of derivative of 11′-epi-brevipolide H
Gullapalli Kumaraswamy, Neerasa Jayaprakash, Dasa Rambabu, Aniban Ganguly and Rajkumar Banerjee
Org. Biomol. Chem., 2014,12, 1793-1803
DOI: 10.1039/C3OB42367K, Paper; Download PDF

The first convergent total synthesis of penarolide sulfate A₂, a novel α-glucosidase inhibitor
Yangguang Gao, Qiuli Shan, Jun Liu, Linlin Wang and Yuguo Du
Org. Biomol. Chem., 2014,12, 2071-2079
DOI: 10.1039/C3OB42364F, Paper; Download PDF

Reaction pathways and free energy profiles for cholinesterase-catalyzed hydrolysis of 6-monoacetylmorphine
Yan Qiao, Keli Han and Chang-Guo Zhan
Org. Biomol. Chem., 2014,12, 2214-2227
DOI: 10.1039/C3OB42464B, Paper; Download PDF

Enzyme-promoted regioselective coupling oligomerization of isorhapontigenin towards the first synthesis of (±)-gnetulin
Wenling Li, Shixia Yang, Teng Lv and Yadong Yang
Org. Biomol. Chem., 2014,12, 2273-2279
DOI: 10.1039/C3OB42456A, Paper; Download PDF

We hope you enjoy this selection! Let us know what you think…

… and why not submit your latest natural product research to OBC today?

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although your best bet is for you to sign up to OBC’s e-alert (free service), and receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Construction of the basic skeleton of ophiobolin A and variecolin
Ke Li, Cheng Wang, Gang Yin and Shuanhu Gao
Org. Biomol. Chem., 2013,11, 7550-7558
DOI: 10.1039/C3OB41693C

Effective synthesis of kynurenine-containing peptides via on-resin ozonolysis of tryptophan residues: synthesis of cyclomontanin B
Clarence T. T. Wong, Hiu Yung Lam and Xuechen Li
Org. Biomol. Chem., 2013,11, 7616-7620
DOI: 10.1039/C3OB41631C

Characterization of CYP76AH4 clarifies phenolic diterpenoid biosynthesis in the Lamiaceae
Jiachen Zi and Reuben J. Peters
Org. Biomol. Chem., 2013,11, 7650-7652
DOI: 10.1039/C3OB41885E

Synthesis of integerrimide A by an on-resin tandem Fmoc-deprotection–macrocyclisation approach
Sirirat Kumarn, Nitirat Chimnoi and Somsak Ruchirawat
Org. Biomol. Chem., 2013,11, 7760-7767
DOI: 10.1039/C3OB41447G

Enantioselective total synthesis of macrolide (+)-neopeltolide
Arun K. Ghosh, Khriesto A. Shurrush and Zachary L. Dawson
Org. Biomol. Chem., 2013,11, 7768-7777
DOI: 10.1039/C3OB41541D

We hope you enjoy this selection! Let us know what you think…
… and why not submit your latest natural product research to OBC today?

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although your best bet is for you to sign up to OBC’s e-alert (free service), and receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Upenamide: trials and tribulations
William P. Unsworth and Richard J. K. Taylor
Org. Biomol. Chem., 2013,11, 7250-7261
DOI: 10.1039/C3OB41519H

Enantioselective synthesis of encecaline-derived potent antimalarial agents
Dipak Harel, Dirk Schepmann, Reto Brun, Thomas J. Schmidt and Bernhard Wünsch
Org. Biomol. Chem., 2013,11, 7342-7349
DOI: 10.1039/C3OB41583J

How a diversity-oriented approach has inspired a new hypothesis for the gabosine biosynthetic pathway. A new synthesis of (+)-gabosine C
Miguel Ángel Fresneda, Ramon Alibés, Josep Font, Pau Bayón and Marta Figueredo
Org. Biomol. Chem., 2013,11, 6562-6568
DOI: 10.1039/C3OB41183D

Synthesis of a C1–C11 fragment of Zincophorin using planar chiral, neutral π-allyl iron complexes  
John P. Cooksey  
Org. Biomol. Chem., 2013, 11, 5117-5126
DOI: 10.1039/C3OB40894A

First synthesis of antitumoral dasyscyphin B
Ali Akhaouzan, Antonio Fernández, Ahmed I. Mansour, Esteban Alvarez, Ali Haidöur, Ramón Alvarez-Manzaneda, Rachid Chahboun and Enrique Alvarez-Manzaneda
Org. Biomol. Chem., 2013,11, 6176-6185
DOI: 10.1039/C3OB41290C

Doubly prenylated tryptamines: cytotoxicity, antimicrobial activity and cyclisation to the marine natural product flustramine A
Santosh Kumar Adla, Florenz Sasse, Gerhard Kelter, Heinz-Herbert Fiebig and Thomas Lindel
Org. Biomol. Chem., 2013,11, 6119-6130
DOI: 10.1039/C3OB40896E

Approach to the functionalized cyclopentane core of marine prostanoids by applying a radical cyclization of β-disubstituted acrylates
Lisa P. T. Hong, Christopher Chak and Christopher D. Donner
Org. Biomol. Chem., 2013,11, 6186-6194
DOI: 10.1039/C3OB41263F

We hope you enjoy this selection! Let us know what you think…

… and why not submit your latest natural product research to OBC today?

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although your best bet is for you to sign up to OBC’s e-alert (free service), and receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Concise synthesis of (−)-steviamine and analogues and their glycosidase inhibitory activities
Nadechanok Jiangseubchatveera, Marc E. Bouillon, Boonsom Liawruangrath, Saisunee Liawruangrath, Robert J. Nash and Stephen G. Pyne
DOI: 10.1039/C3OB40374B, Paper

Synthesis of the decalin core of codinaeopsin via an intramolecular Diels–Alder reaction
Mani Ramanathan, Chun-Jui Tan, Wen-Jung Chang, Hui-Hsu Gavin Tsai and Duen-Ren Hou
DOI: 10.1039/C3OB40480C, Paper

Synthesis and antiproliferative activity of selenoindirubins and selenoindirubin-N-glycosides
Friedrich Erben, Dennis Kleeblatt, Marcel Sonneck, Martin Hein, Holger Feist, Thomas Fahrenwaldt, Christine Fischer, Abdul Matin, Jamshed Iqbal, Michael Plötz, Jürgen Eberle and Peter Langer
DOI: 10.1039/C3OB40603B, Paper

Total syntheses of oroidin, hymenidin and clathrodin
Sivappa Rasapalli, Venkatreddy Kumbam, Abasaheb N. Dhawane, James A. Golen, Carl J. Lovely and Arnold L. Rheingold
DOI: 10.1039/C3OB40668G, Communication

Synthesis and biological evaluation of new paclitaxel analogs and discovery of potent antitumor agents
Kyriacos C. Nicolaou and Roman A. Valiulin
DOI: 10.1039/C3OB40654G, Paper

First studies directed towards the diastereoselective synthesis of the BCD tricyclic core of brownin F
Fabien Rodier, Jean-Luc Parrain, Gaëlle Chouraqui and Laurent Commeiras
DOI: 10.1039/C3OB40363G, Paper

Protein engineering of oxidosqualene-lanosterol cyclase into triterpene monocyclase
Cheng-Hsiang Chang, Hao-Yu Wen, Wen-Shiang Shie, Ching-Ting Lu, Meng-Erh Li, Yuan-Ting Liu, Wen-Hsuan Li and Tung-Kung Wu
DOI: 10.1039/C3OB40493E, Paper

We hope you enjoy this selection! Let us know what you think…

… and why not submit your latest natural product research to OBC today?

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although your best bet is for you to sign up to OBC’s e-alert (free service), and receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Total synthesis of (+)-pentamethylsalvianolic acid C
Benjamin L. Alford and Helmut M. Hügel
Org. Biomol. Chem., 2013,11, 2724-2727
DOI: 10.1039/C3OB27478K, Paper

Concise total syntheses of (±)-noruleine and (±)-uleine
Süleyman Patir and Erkan Ertürk
Org. Biomol. Chem., 2013,11, 2804-2810
DOI: 10.1039/C3OB40180D, Paper

A concise approach to the spiroiminal fragment of marineosins
Guang Li, Xun Zhang, Qi Li, Pengju Feng and Yian Shi
Org. Biomol. Chem., 2013,11, 2936-2938
DOI: 10.1039/C3OB40208H, Communication

Highly stereoselective directed reactions and an efficient synthesis of azafuranoses from a chiral aziridine
Hogyu Lee, Jun Hee Kim, Won Koo Lee, Jaeheung Cho, Wonwoo Nam, Jaedeok Lee and Hyun-Joon Ha
Org. Biomol. Chem., 2013,11, 3629-3634
DOI: 10.1039/C3OB27390C, Paper

We hope you enjoy this selection! Let us know what you think…

… and why not submit your latest natural product research to OBC today?

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although your best bet is for you to sign up to OBC’s e-alert (free service), and receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Watsonianone A–C, anti-plasmodial β-triketones from the Australian tree, Corymbia watsoniana
Anthony R. Carroll, Vicky M. Avery, Sandra Duffy, Paul I. Forster and Gordon P. Guymer
Org. Biomol. Chem., 2013,11, 453-458
DOI: 10.1039/C2OB26931G, Paper

A mechanistic study on the Hooker oxidation: synthesis of novel indane carboxylic acid derivatives from lapachol
Kenneth O. Eyong, Manohar Puppala, Ponminor Senthil Kumar, Marc Lamshöft, Gabriel N. Folefoc, Michael Spiteller and Sundarababu Baskaran
Org. Biomol. Chem., 2013,11, 459-468
DOI: 10.1039/C2OB26737C, Paper

Synthesis of N,N′-diglycosylated isoindigos
Dennis Kleeblatt, Baraa Siyo, Martin Hein, Viktor O. Iaroshenko, Jamshed Iqbal, Alexander Villinger and Peter Langer
Org. Biomol. Chem., 2013,11, 886-895
DOI: 10.1039/C2OB25866H, Communication

First total synthesis of Debilisone C
Bishwajit Saikia, Thongam Joymati Devi and Nabin C. Barua
Org. Biomol. Chem., 2013,11, 905-913
DOI: 10.1039/C2OB26329G, Paper

Synthesis and biological studies of neopetrosiamides as inhibitors of cancer cell invasion
Kaitlyn M. Towle, Jennifer L. Chaytor, Hongqiang Liu, Pamela Austin, Michel Roberge, Calvin D. Roskelley and John C. Vederas
Org. Biomol. Chem., 2013, Advance Article
DOI: 10.1039/C3OB27238A, Paper

Stereoselective syntheses of racemic quercitols and bromoquercitols starting from cyclohexa-1,4-diene: gala-, epi-, muco-, and neo-quercitol Gökay Aydın, Tahir Savran, Fatih Aktaş, Arif Baran and Metin Balci
Org. Biomol. Chem., 2013, Advance Article
DOI: 10.1039/C3OB26909D, Paper

We hope you enjoy this selection! Let us know what you think…

… and why not submit your latest natural product research to OBC today?