The latest issue of Natural Product Reports is now online, and features a review from Ronald J. Quinn et al. on the cover. Their article examines Protein Fold Topology correlations between natural products and biosynthetic enzymes and therapeutic targets and suggests that this could explain why nature produces such a large proportion of existing drugs.
Also in the issue we have an article from Alvaro M. Vijoen on natural products in anti-obesity therapy, a review from Muhammad Saleem and Karsten Krohn on difficulties in developing new naturally derived antibiotics, and a regular review article from Braulio M. Fraga on natural sesquiterpenoids.