Author Archive

How green are Ionic Liquids?

Because of their distinctive properties, in particular their negligible vapor pressure, ionic liquids have attracted increasing attention in many fields, including organic chemistry, electrochemistry, catalysis, physical chemistry. However, the toxicity including ecotoxicity of these so-called a “green solvent” has recently received broad attention.

In this NJC paper C. S. Pereira and co-workers (collaborative research work between the Universities in the UK and Portugal) have investigated the toxicity of quaternary phosphonium ionic liquids towards fungal conidia Aspergillus nidulans.

This interesting work reveals the mechanism of toxicity of the tetraalkylphosphonium chlorides, demonstrating that systematic elongation of the alkyl substituents result in generally higher toxicity. In this study, fluorescence microscopy is proposed as a direct method for assessing the impact of ionic liquids on the plasma membrane integrity.

Unravelling the mechanism of toxicity of alkyltributylphosphonium chlorides in Aspergillus nidulans conidia; Marija Petkovic, Diego O. Hartmann, Gabriela Adamová, Kenneth R. Seddon, Luís Paulo N. Rebelo and Cristina Silva Pereira; New J. Chem., 2011, Advance Article; DOI: 10.1039/C1NJ20470J, Paper

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On the nucleation of Graphene

In this NJC “Hot article” scientists in Japan have reported that homogeneous single-layer graphene can be obtained by simply annealing the carbon contaminated Cu films deposited on c-plane Al2O3 at 900 and 1000 ˚C without additional carbon supply.

The nucleation mechanism of graphene on the Cu surface has been prepared via Chemical Vapor Deposition (CVD). Furthermore, the authors show that graphitization of amorphous carbon during CVD is effected not only by carbon supersaturation, but it is also affected by CVD temperature and crystallographic plane of the underlying metal. Their results provide direct experimental evidence to elucidate the influencing factors of graphitization of amorphous carbon into graphene.

Exploring the nucleation and mechanism of graphene growth provide important contribution to the graphene research with respect to their further application.

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On the nucleation of graphene by chemical vapor deposition Baoshan Hu, Hiroki Ago, Carlo M. Orofeo, Yui Ogawa and Masaharu Tsuji; New J. Chem., 2011, Advance Article; DOI: 10.1039/C1NJ20695H, Paper

Highly rated by the reviewers and the editorial office alike, this ‘Hot Article’ will be FREE to access for a period of 4 weeks.

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NJC Themed Issue 10 online – in honor of Prof. Didier Astruc

NJC is delighted to introduce this issue in honor of Didier Astruc, on the occasion of his 65th birthday. The outside front cover highlights molecules from 5 of the articles in this issue, placed on a background of grape leaves and vineyards (in honor of Didier’s Bordeaux location).

We’ve invited his colleagues, Jean-René Hamon, Jean-Yves Saillard and Jaime Ruiz, to introduce this special issue and highlight Didier’s many outstanding scientific achievements in a wide range of research areas, including organometallic chemistry, catalysis, molecular chemistry, dendrimers and nanostructures.

Introduction to the themed issue in honour of Prof. Didier Astruc. A success story from electron reservoir complexes to dendritic molecular nanostructures, New J. Chem., 2011, 35, 1931-1932; DOI: 10.1039/C1NJ90032C

The articles presented in this themed issue of NJC address recent developments in material science, cancer research, organometallic complexes, metallodendrimers and preparation of nanostructures, amongst other themes. New ideas are presented, some long-held views are strengthened and others are questioned.

In all, there are 56 articles including 2 Focuses, 4 Perspectives, 6 Letters and 44 Full papers. The high quality of research presented exemplifies what scientists are able to achieve, and Didier Astruc certainly occupies a leading position among them.

Some of the articles in this themed issue:

A new series of ferrocifen derivatives, bearing two aminoalkyl chains, with strong antiproliferative effects on breast cancer cells; Pascal Pigeon, Siden Top, Anne Vessières, Michel Huché, Meral Görmen, Mehdi El Arbi, Marie-Aude Plamont, Michael J. McGlinchey and Gérard Jaouen; New J. Chem., 2011, 35, 2212-2218; DOI: 10.1039/C1NJ20192A

Synthesis of spin crossover nano-objects with different morphologies and properties; Alexey Tokarev, Lionel Salmon, Yannick Guari, Gábor Molnár and Azzedine Bousseksou; New J. Chem., 2011, 35, 2081-2088 DOI:10.1039/C1NJ20218A

A meta-xylenediamide macrocycle containing rotaxane anion host system constructed by a new synthetic clipping methodology; Nicholas H. Evans, Christopher J. Serpell and Paul D. Beer; New J. Chem., 2011, 35, 2047-2053; DOI: 10.1039/C1NJ20109C

The inside front cover by Hiroshi Nishihara and co-workers (University of Tokyo) represents their work on 3-ferrocenylazobenzene (3-FcAB) containing polymer particles, envisioning their potential application to act as nano-sized photo-memories or switches.

Synthesis of photo-switchable 3-FcAB-modified polymer particles by Kosuke Namiki, Masaki Murata, Shoko Kume and Hiroshi Nishihara; New J. Chem., 2011, 35, 2146-2152; DOI: 10.1039/C1NJ20189A

A symposium in honor of Didier Astruc will be held in Bordeaux (December 1–2, 2011) at which Yves Chauvin (2005 Nobel Laureate) will present this themed issue to Didier. The two-day symposium program will include plenary lectures by Henri Kagan and Jean-Pierre Sauvage, 25 other lectures, as well as a Grand Public discussion with Yves Chauvin.

Don’t miss the October themed Issue 10, available online!

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Rapid synthetic access to ferrocenyl benzodiazepines, novel antimalarial drug candidates.

Malaria, caused by single cell protozoon parasites of the Plasmodium species, is a tropical disease causing almost three million deaths every year. The alarming spread of drug resistance and limited number of effective drugs now available underline how important it is to discover new antiplasmodial compounds.

Combining both organometallic and bioorganic characters of molecules into one bio-structure is currently an attractive approach to cancer and malarial therapeutics.

The idea of Pelinsky et al. (University of Lille, France) of “metallo”-derivatising benzodiazepines in a search for new antiplasmodial drugs have led to development of the original synthetic method to prepare new ferrocenyl derivatives of benzodiazepines.

This one-pot procedure using microwave-assisted irradiation allowed preparation of novel ferrocenyl 1,4-benzodiazepin-2-ones in significantly short reaction time and in higher yields compared to the conventional synthetic methods. In collaboration with other French researchers, their antiplasmodial and antiproliferative activities were also investigated.

One-pot microwave-assisted synthesis and antimalarial activity of ferrocenyl benzodiazepines; Gabin Mwande-Maguene, Jouda Jakhlal, Jean-Bernard Lekana-Douki, Elisabeth Mouray, Till Bousquet, Sylvain Pellegrini, Philippe Grellier, Fousseyni Samba Toure Ndouo, Jacques Lebibi and Lydie Pelinski; New J. Chem., 2011, Advance Article; DOI: 10.1039/C1NJ20551J, Letter

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NJC Issue 9 now online!

NJC Issue 9, now published online, covers trends and progress in the areas of supramolecular chemistry, organometallic chemistry, catalysis, nanostructures, material sciences, and much more. This issue also includes a preview of RSC events in 2011/2012.

The outside front cover highlights the article by Lirong Lin (Xiamen University) and Hui Zhang (Zhejiang University) who present a characterization study of stereochemically labile atropisomers by solid-state circular dichroism and UV-Vis spectra.

Concentration effects in solid-state CD spectra of chiral atropisomeric compounds by Lei Ding, Lirong Lin, Chengyong Liu, Hongkun Li, Anjun Qin, Yan Liu, Ling Song, Hui Zhang, Ben Zhong Tang and Yufen Zhao, New J. Chem., 2011, 35, 1781-1786; DOI:10.1039/C1NJ20185A

The inside front cover features work by Mireille Blanchard-Desce and Olivier Mongin from the University of Rennes on design and synthesis of dual-role biphotonic chromophores. The ability to preserve their fluorescence property makes novel banana-shaped fluorophores very attractive molecules for photodynamic therapy (TPA). Furthermore, possible encapsulating of these biphonic fluorophores within nanoparticles is now of high interest.

Banana-shaped biphotonic quadrupolar chromophores: from fluorophores to biphotonic photosensitizers by Cédric Rouxel, Marina Charlot, Youssef Mir, Céline Frochot, Olivier Mongin and Mireille Blanchard-Desce, New J. Chem., 2011, 35, 1771-1780, DOI: 10.1039/C1NJ20073A

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