Professor Alberto Marra (Ecole Nationale Supérieure de Chimie de Montpellier, France) designed the outside cover of this month’s issue, based on the van Gogh painting The Mulberry Tree. In the accompanying Perspective article, Professor Marra and his co-workers review the different strategies developed to synthesize multivalent architectures, from the total synthesis of divalent iminosugars to the preparation of complex systems bearing twenty-five iminosugar units. They also compare the enzyme inhibitory properties of the various multivalent iminosugars prepared to date in order to infer the valence and the three-dimensional arrangement required for the most efficient inhibition activity.
Synthesis and biological properties of multivalent iminosugars
Renaud Zelli, Jean-François Longevial, Pascal Dumy and Alberto Marra
New J. Chem., 2015, 39, 5050-5074. DOI: 10.1039/C5NJ00462D.
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