Archive for August, 2013

Meet Our Authors – August Issue 2013

Two authors of NJC’s August issue are interviewed for this month’s Meet our Authors feature.

Our first author is Dr. Faina Gelman, who is researcher at the Institute of Geological Survey of Israel, The Hebrew University of Jerusalem. Her current research interests are environmental chemistry and stable isotope analysis. She particularly focuses on development of new analytical tools for stable isotope analysis and their applications for understanding chemical and biochemical transformations of organic compounds.

In their NJC paper, Faina with her colleagues demonstrated determination of bromine kinetic isotope effect on Grignard reagent formation –one of the fundamental reactions of brominated organics. ” Since our work combines novel analytical, theoretical and organic chemistry approaches, we wanted to submit it to a more general-focused journal, such as NJC is, from our point of view” commented on choosing NJC.

And what contemporary scientific issue is she most concerned about: “I am very much concerned about environmental pollution and would like to find an efficient way to treat this problem “she replied. Besides her research activity, Faina likes to spend time with her family.

Bromine kinetic isotope effects: insight into Grignard reagent formation by Lukasz Szatkowski, Agnieszka Dybala-Defratyka, Charlie Batarseh, Jochanan Blum, Ludwik Halicz and Faina Gelman ; New J. Chem., 2013, 37, 2241-2244; DOI: 10.1039/C3NJ00197K.

The second author is Jürg Hulliger, who is a Professor of chemistry at the University of Berne, Switzerland. His research interest centers on Crystal growth, properties and solid state theory. His contribution to this month’s issue is Focus article that reviews on polar properties of solid molecular matter.”Here we review basic theoretical views on growth induced polarity in molecular crystals giving also all known experimental examples we have by today, which domonstrate polarity Formation. ”

If Jürg could solve any scientific problem, it would be: “Constructing equipment being able to say : a small Crystal of the size of a few 100 nm is (i) superconductive, (ii) is composed of these elements and (iii) shows this crystal structure. Such an Equipment may be used to analyze your combinatorial ceramic samples.”

In the non-lab world, Jürg is fascinated by interior decoration in the style of the 18th century, renovation of antics and art.

A stochastic principle behind polar properties of condensed molecular matter by Jürg Hulliger, Thomas Wüst, Khadidja Brahimi, Matthias Burgener and Hanane Aboulfadl  New J. Chem., 2013, 37, 2229-2235 DOI: 10.1039/C3NJ40935J

We thanks to Faina and Jürg for accepting our invitation to talk about themselves and their work!

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Three young chemists honoured at the 8th International Dendrimer Symposium

New Journal of Chemistry sponsored 3 poster prizes at the 8th International Dendrimer Symposium that took place this summer in Madrid, continuing its support of this series of symposia and the dendrimer community in general.

Guang Zhang is a 2nd year Ph.D. student in the group of Klaus Müllen at the MPI for Polymer Research in Mainz, Germany. He is conducting research on polyphenylene dendrimers and their applications for fluorescent blue light emitting diodes. Zhang’s poster reported G1 and G2 dendrimers having triphenylamine on the surface and pyrene in the core, which showed promising properties as blue OLED materials. Guang’s reaction to winning the NJC Poster Prize: “It is a great honor for me to receive the prize. It’s also a big surprise that I can have access to NJC for free for one year.”

Surface Functionalized Polyphenylene Dendrimers for Deep Blue Light  Emitting Diodes
G. Zhang, M. Baumgarten, R. Trattnig, M. Auer, E. J. W. List, K. Müllen

The winner from Spain is Javier Sánchez, who currently is a postdoctoral fellow at the Instituto de Investigación Sanitaria Gregorio Marañón, where he also carried out his Ph.D. research in the group of María Ángeles Muñoz Fernández.  The focus of Javier’s research is anti-HIV activity, but always with an eye to the potential clinical applications. He explains: “I always try to elucidate the mechanisms by which the different dendrimers behave as they do on the HIV-1 cycle.” The research presented at the conference looked at the anti-HIV activity of different carbosilane dendrimers. After development of the dendrimers they were tested using toxicity assays, inflammatory cytokines induction, HIV infection and cell phenotyping by flow cytommetry. This has led to a dendrimer that as a microbicide has anti-HIV activity for different HIV viral strains.

Anti-HIV Activity of Thiol-Ene Carbosilane Dendrimers and Potential Topical Microbicide
J. Sánchez-Rodríguez, L. Díaz, M. Galán, M. Maly, R. Gómez, F. J. de la Mata, J. L. Jiménez, M. A. Muñoz- Fernández

The 3rd winner is from the group of Eric Simanek at Texas Christian University in the USA. Changsuk Lee is now a postdoctoral fellow, after having obtained his Ph.D. under the direction of Daniel Romo at Texas A&M University in 2010. Changsuk works towards the development of drug delivery vehicles by using various sizes and shapes of dendrimers; to date triazine dendrimers are the best delivery vehicles among others tested. The winning poster covered the synthesis of a prodrug platform with paclitaxel, its biodistribution, mice efficacy testing, and molecular dynamic simulations.

Synthesis and Biological Assessment of a Triazine Dendrimer with 16 Paclitaxel Groups
C. Lee, S.-T. Lo, J. Lim, V. C. P. da Costa, S. Ramezani, G. M. Pavan, O. Annuziata, X. Sun, E. E. Simanek

Congratulations to all 3 winners, who received a certificate, RSC book and a one-year NJC subscription.

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Your Vacation Reading from NJC

The August issue of New Journal of Chemistry contains 50 articles for your summer reading enjoyment.

Bi-polar states of solid matter.

Among the highlights of this issue, don’t miss the latest Focus review, by the group of Jürg Hulliger at the University of Bern in Switzerland. Using condensed matter theory, the key message that molecular solids can end up in bi-polar states has implications for tissue formation, function and repair. This is an interesting example of how findings in one field might lead to breakthroughs in a very different field.

A stochastic principle behind polar properties of condensed molecular matter by Jürg Hulliger, Thomas Wüst, Khadidja Brahimi, Matthias Burgener and Hanane Aboulfadl, New J. Chem., 2013, 37, 2229-2235. DOI: 10.1039/C3NJ40935J

Cover for the work of Mikata et al.

The outside and inside front covers feature highly ranked works. This month the striking outside front cover was proposed by the group of Yuji Mikata from Nara Women’s University in Japan. They achieved OFF-ON, ratiometric or ON-OFF responses towards mercury and iron cations by modifying the substitution pattern on their basic molecular skeleton.

Thioether-tethered bisquinoline derivatives as fluorescent probes for mercury(II) and iron(III) ions by Yuji Mikata, Fumie Nakagaki and Kaori Nakanishi, New J. Chem., 2013, 37, 2236-2240. DOI: 10.1039/C3NJ00233K

Cover for the work of Andruh and collaborators.

A collaborative effort by several groups in Romania and France is featured on the inside front cover. They determined the crystal structures and studied the magnetic and photophysical properties of sixteen 3d–4f Schiff-base complexes. The interaction between the two metal ions lead to interesting effects on the properties.

A new synthetic route towards binuclear 3d–4f complexes, using non-compartmental ligands derived from o-vanillin. Syntheses, crystal structures, magnetic and luminescent properties by Masood Sarwar, Augustin M. Madalan, Carmen Tiseanu, Ghenadie Novitchi, Catalin Maxim, Gabriela Marinescu, Dominique Luneau and Marius Andruh, New J. Chem., 2013, 37, 2280-2292. DOI: 10.1039/C3NJ00199G

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