In this NJC “Hot Article”, Jian Hua Zhu and co-workers at Nanjing University (China) describe the immobilization of Horseradish peroxidase (HRP) on periodic mesoporous organosilicas (PMO).
It is demonstrated that the enzyme activity is enhanced 110% compared with free HRP in solution. Besides, the stability of immobilized HRP to lower pH values or the denaturing agent urea is enhanced, resulting from interfacial activation of the enzyme when it is attached to a surface filled with organic groups and hydrophobic parts. The thermal stability of immobilized HRP on PMO is also increased and, moreover, the HRP immobilized samples can be reusable for many cycles.
“Elevating enzyme activity through the immobilization of horseradish peroxidase onto periodic mesoporous organosilicas” Na Lin, Ling Gao, Zhe Chen and Jian Hua Zhu, New J. Chem., 2011, Advance Article. DOI: 10.1039/C1NJ20311H.
Take time to have a look at it now ! Highly rated by the reviewers and the editorial office, this “Hot Article” will be FREE to access for a period of 4 weeks.
