A native enzyme, which catalyzes stereoselective aldol reactions, was successfully encapsulated in an inorganic support by Forano, Lemaire, and co-workers. This biocatalyst maintains 100% of enzyme activity through a series of different condensation reactions. In addition, the immobilized enzyme is stable under storage and can be reused several times without a notable loss of activity, highlighting its suitability for organic synthesis.
Efficient immobilization of fructose-6-phosphate aldolase in layered double hydroxide: improved stereoselective synthesis of sugar analogues
Christine Guérard-Hélaine, Bertrand Légeret, Carlos Fernandes, Vanessa Prévot, Claude Forano and Marielle Lemaire
New J. Chem., 2011, Advance Article
DOI: 10.1039/C0NJ00956C, Letter
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