MedChemComm Issue 3 is here

Welcome to MedChemComm Issue 3!

In this new issue, you’ll find a new collection of exciting papers on medicinal chemistry research, which you can download for free!

This month’s menu includes:

The importance of solvation in the design of ligands targeting membrane proteins

Repairing faulty genes by aminoglycosides: Identification of new pharmacophore with enhanced suppression of disease-causing nonsense mutations

Synthesis and anti HSV-1 evaluation of novel indole-3,4-diones

Novel indolizine compounds as potent inhibitors of phosphodiesterase IV (PDE4): structure–activity relationship

Scaffold-hopping from aminoglycosides to small synthetic inhibitors of bacterial protein biosynthesis using a pseudoreceptor model

The discovery of a novel prototype small molecule TLR7 agonist for the treatment of hepatitis C virus infection

Synthesis and biological evaluation of novel ferrocenyl curcuminoid derivatives

Interactions of polysulfanes with components of red blood cells

Structure-based design, synthesis, and profiling of potent and selective neuronal nitric oxide synthase (nNOS) inhibitors with an amidinothiophene hydroxypiperidine scaffold

Carba-LNA modified siRNAs targeting HIV-1 TAR region downregulate HIV-1 replication successfully with enhanced potency

That is a great selection, isn’t it? We hope you enjoy it and you find it enlightening.

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)

Leave a Reply