Christian Heinis and Lisa Pollaro talk about different strategies to prolong the in vivo plasma residence time of peptides.
Several strategies that extend the elimination half-life of peptides from minutes to several hours or even days are described in this interesting review.
You can read it for free here
Strategies to prolong the plasma residence time of peptide drugs
Lisa Pollaro and Christian Heinis
Med. Chem. Commun., 2010, Advance Article
DOI: 10.1039/C0MD00111B, Review
