Oishi, Fujii and co-workers report on the affinity-based screening technology and sequence-activity relationships for aminoacid optimization in HIV-1 fusion inhibitors directed against enfuvirtide-resistant HIV strains.
Find out more about this affinity selection-mass spectrometry method to explore novel HIV-1 fusion inhibitors. Do you have anything to say? Comment on it!
Affinity selection and sequence-activity relationships of HIV-1 membrane fusion inhibitors directed at the drug-resistant variants
Shinya Oishi, Kentaro Watanabe, Saori Ito, Michinori Tanaka, Hiroki Nishikawa, Hiroaki Ohno, Kazuki Shimane, Kazuki Izumi, Yasuko Sakagami, Eiichi N. Kodama, Masao Matsuoka, Akira Asai and Nobutaka Fujii
Med. Chem. Commun., 2010, Advance Article
DOI: 10.1039/C0MD00091D , Concise Article
