This month sees the following articles in MedChemComm that are in the top ten most accessed:-
Chemical space as a source for new drugs
Jean-Louis Reymond, Ruud van Deursen, Lorenz C. Blum and Lars Ruddigkeit
Med. Chem. Commun., 2010, 1, 30-38, DOI: 10.1039/C0MD00020E
Small molecule modulation of stem cells in regenerative medicine: recent applications and future direction
Timothy E. Allsopp, Mark E. Bunnage and Paul V. Fish
Med. Chem. Commun., 2010, 1, 16-29, DOI: 10.1039/C0MD00055H
Design, synthesis, and structure–activity relationships of indole-3-carboxamides as novel water soluble cannabinoid CB1 receptor agonists
Julia M. Adam, Jim Cairns, Wilson Caulfield, Phillip Cowley, Iain Cumming, Morag Easson, Darren Edwards, Morag Ferguson, Richard Goodwin, Fiona Jeremiah, Takao Kiyoi, Ashvin Mistry, Elizabeth Moir, Richard Morphy, Jason Tierney, Mark York, James Baker, Jean E. Cottney, Andrea K. Houghton, Paul J. Westwood and Glenn Walker
Med. Chem. Commun., 2010, 1, 54-60, DOI: 10.1039/C0MD00022A
Silver nanoparticles—the real “silver bullet” in clinical medicine?
Kenneth K. Y. Wong and Xuelai Liu
Med. Chem. Commun., 2010, 1, 125-131, DOI: 10.1039/C0MD00069H
An absolute structure template for a unique voltage-gated sodium channel binding site
Rex A. Palmer, Brian S. Potter, Michael J. Leach, Terence C. Jenkins and Babur Z. Chowdhry
Med. Chem. Commun., 2010, 1, 45-49, DOI: 10.1039/C0MD00043D
Synthesis and biological activity of new pyridonediaryl ether non-nucleoside inhibitorsof HIV-1 reverse transcriptase
Joshua J. Kennedy-Smith, Nidhi Arora, J. Roland Billedeau, Jennifer Fretland, Julie Q. Hang, Gabrielle M. Heilek, Seth F. Harris, Donald Hirschfeld, Hassan Javanbakht, Yu Li, Weiling Liang, Ralf Roetz, Mark Smith, Guoping Su, Judy M. Suh, Armando G. Villaseñor, Jeffrey Wu, Dennis Yasuda, Klaus Klumpp and Zachary K. Sweeney
Med. Chem. Commun., 2010, 1, 79-83, DOI: 10.1039/C0MD00009D
Histamine H3receptor ligands with a 3-cyclobutoxy motif: a novel and versatile constraint of the classical 3-propoxy linker
Maikel Wijtmans, Frédéric Denonne, Sylvain Célanire, Michel Gillard, Saskia Hulscher, Christel Delaunoy, Nathalie Van houtvin, Remko A. Bakker, Sabine Defays, Julien Gérard, Luc Grooters, Delphine Hubert, Henk Timmerman, Rob Leurs, Patrice Talaga, Iwan J. P. de Esch and Laurent Provins
Med. Chem. Commun., 2010, 1, 39-44, DOI: 10.1039/C0MD00056F
Effect of particle shape on phagocytosisof CdTe quantum dot–cystinecomposites
Zhisong Lu, Yan Qiao, Xin Ting Zheng, Mary B. Chan-Park and Chang Ming Li
Med. Chem. Commun., 2010, 1, 84-86, DOI: 10.1039/C0MD00008F
Synthesis and NMDAreceptor affinity of dexoxadrolanalogues with modifications in position 4 of the piperidine ring
Ashutosh Banerjee, Roland Fröhlich, Dirk Schepmann and Bernhard Wünsch
Med. Chem. Commun., 2010, 1, 87-102, DOI: 10.1039/C0MD00017E
Synthesis and selective inhibition of human monoamine oxidasesof a large scaffold of (4,5-substituted-thiazol-2-yl)hydrazones Franco Chimenti, Daniela Secci, Adriana Bolasco, Paola Chimenti, Arianna Granese, Simone Carradori, Melissa D’Ascenzio, Matilde Yáñez and Francisco Orallo
Med. Chem. Commun., 2010, 1, 61-72, DOI: 10.1039/C0MD00014K
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