Interested? Why not take a look at the article, we’ve made it free to access for the next 2 weeks:
Micromagnetic–microfluidic blood cleansing device
Chong Wing Yung, Jason Fiering, Andrew J. Mueller and Donald E. Ingber
Lab Chip, 2009, 9, 1171-1177
DOI: 10.1039/B816986A
This issue features some particularly striking cover artwork and a whole host of HOT articles.
The outside front cover from Kyubong Jo (Sogang University, Seoul) and David Schwartz (University of Wisconsin–Madison) describes their HOT article on elongating DNA molecules in nanochannels, where they achieve almost full contour length:
Nanochannel confinement: DNA stretch approaching full contour length
Yoori Kim, Ki Seok Kim, Kristy L. Kounovsky, Rakwoo Chang, Gun Young Jung, Juan J. dePablo, Kyubong Jo and David C. Schwartz
The inside front cover features work by Rajeev Ram (MIT) et al. on their device for automated microscale continuous culture experiments:
Microfluidic chemostat and turbidostat with flow rate, oxygen, and temperature control for dynamic continuous culture
Kevin S. Lee, Paolo Boccazzi, Anthony J. Sinskey and Rajeev J. Ram
Other HOT articles in this issue include:
Air stream-mediated vortex agitation of microlitre entities on a fluidic chip
Matthias Geissler, Benoît Voisin and Teodor Veres
Integrated ionic liquid-based electrofluidic circuits for pressure sensing within polydimethylsiloxane microfluidic systems
Chueh-Yu Wu, Wei-Hao Liao and Yi-Chung Tung
Tracking and synchronization of the yeast cell cycle using dielectrophoretic opacity
Ana Valero, Thomas Braschler, Alex Rauch, Nicolas Demierre, Yves Barral and Philippe Renaud
A cell-based biosensor for real-time detection of cardiotoxicity using lensfree imaging
Sang Bok Kim, Hojae Bae, Jae Min Cha, Sang Jun Moon, Mehmet R. Dokmeci, Donald M. Cropek and Ali Khademhosseini
Lab on a Chip’s Chips and Tips has a new home!
Chips and Tips is a unique and regularly updated forum for scientists in the miniaturisation field which aims to provide a place where ideas and solutions can be exchanged on common practical problems encountered in the lab, which are seldom reported in the literature.
So far we have published over 50 Tips to make miniaturisation easier and we hope that the new blog will provide an even better forum for discussions and ideas to be exchanged.
Why not take a look at our shiny new blog today!
https://blogs.rsc.org/chipsandtips/
The Pioneers of Miniaturisation Lecture is awarded annually to an early to mid-career scientist for extraordinary or outstanding contributions to the understanding or development of miniaturised systems. This year’s presentation of the award will take place during the uTAS conference in Seattle, USA in October 2011. The Lectureship is jointly awarded by the Royal Society of Chemistry’s Lab on a Chip journal and Corning Incorporated and includes $5000 ($2000 of which may be used to attend the µTAS Symposium).
Nominations are now invited for this award – the deadline for nominations is 20th May 2011. Full details of the criteria and how to submit the nominations are to be found on the Pioneers of Miniaturisation Lecture webpage which also provides more information about the award.
Phaseguides: a paradigm shift in microfluidic priming and emptying
Paul Vulto, Susann Podszun, Philipp Meyer, Carsten Hermann, Andreas Manz and Gerald A. Urban
Lab Chip, 2011, 11, 1596-1602
Solid phase extraction of DNA from biological samples in a post-based, high surface area poly(methyl methacrylate) (PMMA) microdevice
Carmen R. Reedy, Carol W. Price, Jeff Sniegowski, Jerome P. Ferrance, Matthew Begley and James P. Landers
Lab Chip, 2011, 11, 1603-1611
The issue also features a Focus article from Holger Becker on his wish-list of unsolved technological issues — which is part of our series of Focus articles on the commercialization of microfluidics.
All I want for Christmas…
Holger Becker
Lab Chip, 2011, 11, 1571-1573
Work published in Lab on a Chip features heavily in Nature’s latest Special Technology Feature ‘Tissue models: A living system on a chip‘.
The article, summarising the current state-of-the-art in creating living tissue models on chips, references work from LOC Editorial Board member Donald Ingber (Harvard Medical School) and LOC publications from Michael Shuler (Cornell), John March (Cornell), Linda Griffith (MIT) and Axel Günther (University of Toronto).
We’ve made these great articles free to access for 2 weeks – why not take a look!
A microfluidic device for a pharmacokinetic–pharmacodynamic (PK–PD) model on a chip
Jong Hwan Sung, Carrie Kam and Michael L. Shuler
Lab Chip, 2010, 10, 446-455
Microscale 3-D hydrogel scaffold for biomimetic gastrointestinal (GI) tract model
Jong Hwan Sung, Jiajie Yu, Dan Luo, Michael L. Shuler and John C. March
Lab Chip, 2010, 11, 389-392
Perfused multiwell plate for 3D liver tissue engineering
Karel Domansky, Walker Inman, James Serdy, Ajit Dash, Matthew H. M. Lim and Linda G. Griffith
Lab Chip, 2010, 10, 51-58
A microfluidic platform for probing small artery structure and function
Axel Günther, Sanjesh Yasotharan, Andrei Vagaon, Conrad Lochovsky, Sascha Pinto, Jingli Yang, Calvin Lau, Julia Voigtlaender-Bolz and Steffen-Sebastian Bolz
Lab Chip, 2010, 10, 2341-2349
From our 2010 Emerging Investigators themed issue
This month’s issue features another great selection of articles, including a Focus article from Mathias Uhlen and Helene Andersson Svahn on affinity reagents for lab on a chip applications.
A microfabricated electrical differential counter for the selective enumeration of CD4+ T lymphocytes
Nicholas N. Watkins, Supriya Sridhar, Xuanhong Cheng, Grace D. Chen, Mehmet Toner, William Rodriguez and Rashid Bashir
A device for extraction, manipulation and stretching of DNA from single human chromosomes
Kristian H. Rasmussen, Rodolphe Marie, Jacob M. Lange, Winnie E. Svendsen, Anders Kristensen and Kalim U. Mir
Microparticle and cell counting with digital microfluidic compact disc using standard CD drive
Syed M. Imaad, Nathan Lord, Gulsim Kulsharova and Gang Logan Liu
Other HOT articles in this issue include:
Integrated photocatalytic micropillar nanoreactor electrospray ionization chip for mimicking phase I metabolic reactions
Teemu Nissilä, Lauri Sainiemi, Mika-Matti Karikko, Marianna Kemell, Mikko Ritala, Sami Franssila, Risto Kostiainen and Raimo A. Ketola
Capillary-driven automatic packaging
Yuzhe Ding, Lingfei Hong, Baoqing Nie, Kit S. Lam and Tingrui Pan
A magnetic bead-based assay for the rapid detection of methicillin-resistant Staphylococcus aureus by using a microfluidic system with integrated loop-mediated isothermal amplification
Chih-Hung Wang, Kang-Yi Lien, Jiunn-Jong Wu and Gwo-Bin Lee
Highlighted on the front cover is work by John deMello and colleagues, applying enhanced temperatures for micro continuous-flow synthesis of nanoparticles with excellent reaction control:
A stable droplet reactor for high temperature nanocrystal synthesis
A. M. Nightingale, S. H. Krishnadasan, D. Berhanu, X. Niu, C. Drury, R. McIntyre, E. Valsami-Jones and J. C. deMello
On the inside front cover we have work from Miles Padgett and Roberto Di Leonardo. In their critical review they provide a comprehensive overview of optical tweezers and holographic optical tweezers for lab-on-a-chip applications:
Holographic optical tweezers and their relevance to lab on chip devices
Miles Padgett and Roberto Di Leonardo
The issue also includes HOT articles on observations of the positional dependence of particles in microfludic impedance cytometry, a great new method for fast, cheap PDMS patterning using direct UV lithography and on the back cover we highlight a microfluidic paper-based chemiluminescence biosensor for simultaneous glucose and uric acid developed by Jinghua Yu et al.
Congratulations to Professor Brian Kirby from Cornell who won the ‘guess the baby’ competition held during the microTAS meeting in Groningen and NanoBioTech conference in Montreux last year. Our lucky winner received a state of the art digital photo frame.
The competition, organized by Lab on a Chip Editor Harp Minhas, challenged participants to correctly match the name of a leading member of the microfluidics community with the childhood photo of that person. Why not take a look yourself and see how many you can correctly identify!
Find out more about what happened at microTAS by viewing the abstracts for free here and read about the Pioneer Prize winner, Steve Quake. Take a look at issue 6 of Lab on a Chip which includes an article covering the 2010 Art in Science Award given at mTAS 2010 and featured on the cover of this issue.
Lab on a Chip will be attending the 2011 International Symposium on Microchemistry and Microsystems, hosted at the KBCS Spring Meeting in Seoul, Korea from 2-4 June 2011.
ISMM is the international forum on Micro Total Analysis Systems (μTAS) in Asia region. Following Kanazawa (2009) and Hong Kong (2010), the main topic in the year 2011 will be the “Future of Miniaturized Systems”. ISMM 2011 in Seoul will be jointly held at the same place in the conjunction with an Annual Spring Meeting of the Korean BioChip Society. We anticipate about 400+ scientists and professionals engaged in research of micro and nanosystems for chemistry and life science.
Chaired by SangHoon Lee (Korea University) the program includes many excellent speakers, including:
Luke P. Lee (University of California at Berkeley, USA)
Marc Madou (University of California at Irvine, USA)
Andrew de Mello (Imperial College London, UK)
Minoru Seki (Chiba University, Japan)
Bingcheng Lin (Chinese Academy of Sciences, China)
DongPyo Kim (Chungnam National University, Korea)
The deadline for abstract submissions has just been extended to March 14th 2011, so hurry and submit yours today! Submission information can be found online here.
