Lab on a Chip Blog

Another great issue of LOC is now available online, including Paul Vulto et al.‘s HOT article describing their new phaseguide technology for filling and emptying of microfluidic structures, independent of the chamber and channel geometry, which is highlighted on the outside front cover.

Phaseguides: a paradigm shift in microfluidic priming and emptying
Paul Vulto, Susann Podszun, Philipp Meyer, Carsten Hermann, Andreas Manz and Gerald A. Urban
Lab Chip, 2011, 11, 1596-1602

On the inside front cover we have another HOT article from James P. Landers et al. describing a PMMA microfluidic DNA purification device with embedded microfabricated posts, which have been functionalized to allow for pH-induced DNA binding.

Solid phase extraction of DNA from biological samples in a post-based, high surface area poly(methyl methacrylate) (PMMA) microdevice
Carmen R. Reedy, Carol W. Price, Jeff Sniegowski, Jerome P. Ferrance, Matthew Begley and James P. Landers
Lab Chip, 2011, 11, 1603-1611

The issue also features a Focus article from Holger Becker on his wish-list of unsolved technological issues — which is part of our series of Focus articles on the commercialization of microfluidics.

All I want for Christmas…
Holger Becker
Lab Chip, 2011, 11, 1571-1573

View the full issue here