Organ-on-a-chip technology has rapidly gained prominence and relevance at the interface between biology and engineering due to its burgeoning potential to revolutionise biomedical research and clinical applications. These micro-engineered devices mimic the physiological functions of human organs, providing powerful microfluidic platforms for disease modelling, drug testing and therapeutics, and personalised medicine.
In this Thematic Collection, led by Thought Leaders Séverine Le Gac, Roger Kamm, Yi-Chin Toh & Tae-Eun Park, we aim to highlight the most innovative and ground-breaking advancements in organ-on-a-chip technology and applications at the forefront of the field.
Submissions of interest will significantly build upon existing models and open new avenues of research and applications by providing cutting-edge solutions to pressing problems. In recognising the multidisciplinary nature and impact of organ-on-chips, we are emphasising the collaboration between academia, industry, and clinical partners and welcome contributions that demonstrate the translation of pioneering research into practical and clinical applications for human health and disease.
Topics of particular interest include, but are not limited to:
- Emerging therapies beyond small drugs
- New model designs
- Digital twins and artificial intelligence (AI) integration and analysis
- Advanced sensing and measurement technologies (integrated sensors, RNA Seq, proteomics, spatial omics, multi-omics, real-time measurements, etc.)
- Bioprinting techniques
- Standardisation
- Diverse cell types (cell lines, primary cells, iPSCs, ex vivo tissues)
- Multi-organ-on-chip and body-on-chip systems
This seminal collection will showcase select papers and their investigators that look towards the future – highlighting the most forward-thinking developments in the field of organ-on-a-chip technology.
We invite research and review papers in these and related topics. Accepted articles will be published in an online collection as soon as they are publishable and will be promoted extensively both as they are published and in the final collection.
The deadline for submission to this collection will be December 1st, 2024. If you are interested in submitting a contribution, please do get in touch (LOC-RSC@rsc.org) to discuss this further.
