Archive for October, 2012

Metals in health & nutrition

Vitamin pills with different metals indicated on eachMetals play an important role in human health and nutrition.  Some, such as zinc, copper and iron have vital roles within the body and therefore regular intake is essential.  However, an excess of these metals, or consumption of metal contaminants such as cadmium or arsenic, can have significant detrimental effects on our health.

 The collection of articles below encompasses all aspects of metals in health from their dietary sources and quantitative analysis to the impact these metals can have on our health.  Enjoy these articles from Analytical Methods, Food & Function and Metallomics for free*

Click here for the full list of articles

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Issue 11 of Food & Function now online

The latest issue of Food & Function is now available online.

The front cover of this issue features work by Tony McGhie and colleagues from The New Zealand Institute for Plant & Food Research, and Nutrigenomics, New Zealand.  The authors report the combined use of analytical-scale HPLC with a high sensitivity time-resolved fluorescence coupled with fluorescence resonance energy transfer (TR-FRET) to detect the JAK2 inhibitory activity of Boysenberry drink.  The authors found that of the 84 fractions obtained from the Boysenberry drink, ellagitannin and ellagic acid fractors inhibited JAK2 activity.  Interestingly, whilst anthocyanins made up the majority of the phytochemical components of the drink and have previously been shown to have anti-inflammatory activity, they did not demonstrate any JAK2 activity.

Read the article for free for 6 weeks!

The combination of analytical-scale HPLC separation with a TR-FRET assay to investigate JAK2 inhibitory compounds in a Boysenberry drink, Tony K. McGhie, Harry Martin and Rona C. M. Lunken, Food Funct., 2012, 14, 1170-1175

You can keep up to date with the latest developments from Food & Function by signing up for free table of contents alerts and monthly e-newsletters.

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Improved breads for Celiac disease sufferers

Celiac disease is an autoimmune disease which results in an intolerance to gluten ingestion. Currently, the only treatment available for Celiac disease sufferers is to abide by a gluten-free diet, but this is often difficult as gluten is found in many food products which contain wheat, rye and barley. Therefore gluten-free breads and similar foods are becomming increasingly popular with Celiac sufferers, however the fibre content of these products is usually low. Now, researchers from Sao Paulo, Brazil, have investigated the effects of increasing levels of prebiotic inulin-type fructans (ITFs – soluble dietary fibers) on the sensory and nutritional quality of gluten-free bread.

The research team found that adding ITFs to the gluten-free bread provides additional structure and gas retention during baking, thus improving the bread quality by creating softer crumbs and an improved crust, which improve the sensory enjoyment. The in vitro and in vivo glycemic responses were also studied and it was found that addition of 12% ITF was sufficient to decrease the glycemic response of gluten-free bread. This results in breads with a low glycemic index that are high in prebiotic dietary fibre and can benefit patients with either celiac disease or diabetes.

Read the full article for free until the 15th November 2012:

Effects of prebiotic inulin-type fructans on structure, quality, sensory acceptance and glycemic response of gluten-free breads, V. D. Capriles and J. A. G. Areas, Food Funct., 2012, DOI: 10.1039/c2fo10283h

You can keep up to date with the latest developments from Food & Function by signing up for free table of contents alerts and monthly e-newsletters.

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2nd Oxford Functional Food Conference

2nd Oxford Functional Food Conference 2012

The 2nd Oxford Function Food Conference is being held at The Oxford Hotel from the 13th-14th November 2012

The focus of the conference this year will be on functional foods and the role they play in helping to tackle obesity, diabetes and inflammation.  The 2-day programme will include contributions from the UK, Europe, Canada and the US in the form of plenary lectures, symposium sessions and poster sessions.  The full provisional programme and working titles for all the talks can be found found here.

Registration for the event is now open!  Early Bird registration closes on the 19th October, and the registration deadline is the 28th October.  Please go to the conference website for registration rates and the online registration link.

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Top ten most accessed articles in August

This month sees the following articles in Food & Function that are in the top ten most accessed:-

Anti-inflammatory activity of natural dietary flavonoids
Min-Hsiung Pan, Ching-Shu Lai and Chi-Tang Ho
Food Funct., 2010,1, 15-31, DOI: 10.1039/C0FO00103A, Review Article

Transcription profiles of LPS-stimulated THP-1 monocytes and macrophages: a tool to study inflammation modulating effects of food-derived compounds
Wasaporn Chanput, Jurriaan Mes, Robert A. M. Vreeburg, Huub F. J. Savelkoul and Harry J. Wichers
Food Funct., 2010,1, 254-261, DOI: 10.1039/C0FO00113A

Nuts, especially walnuts, have both antioxidant quantity and efficacy and exhibit significant potential health benefits
Joe A. Vinson and Yuxing Cai
Food Funct., 2012, Advance Article, DOI: 10.1039/C2FO10152A

Review of in vitro digestion models for rapid screening of emulsion-based systems
David Julian McClements and Yan Li
Food Funct., 2010,1, 32-59, DOI: 10.1039/C0FO00111B, Review Article

Antitumor activity of mushroom polysaccharides: a review
Lu Ren, Conrad Perera and Yacine Hemar
Food Funct., 2012, Advance Article, DOI: 10.1039/C2FO10279J, Review Article

Effects of tea and coffee on cardiovascular disease risk
Siv K Bøhn, Natalie C Ward, Jonathan M Hodgson and Kevin D Croft
Food Funct., 2012, Advance Article, DOI: 10.1039/C2FO10288A

Mango fruit peel and flesh extracts affect adipogenesis in 3T3-L1 cells
Meng-Wong Taing, Jean-Thomas Pierson, Van L. T. Hoang, Paul N. Shaw, Ralf G. Dietzgen, Michael J. Gidley, Sarah J. Roberts-Thomson and Gregory R. Monteith
Food Funct., 2012,3, 828-836, DOI: 10.1039/C2FO30073G, Paper

Quercetin-3-O-glucuronide affects the gene expression profile of M1 and M2a human macrophages exhibiting anti-inflammatory effects
Eleonora Derlindati, Margherita Dall’Asta, Diego Ardigò, Furio Brighenti, Ivana Zavaroni, Alan Crozier and Daniele Del Rio
Food Funct., 2012, Advance Article, DOI: 10.1039/C2FO30127J, Paper

Capacity of peroxyl radical scavenging and inhibition of lipid peroxidation by ß-carotene, lycopene, and commercial tomato juice
Mizuki Takashima, Mototada Shichiri, Yoshihisa Hagihara, Yasukazu Yoshida and Etsuo Niki
Food Funct., 2012, Advance Article, DOI: 10.1039/C2FO30119A, Paper

Effects of eggs on plasma lipoproteins in healthy populations
Maria Luz Fernandez
Food Funct., 2010,1, 156-160, DOI: 10.1039/C0FO00088D, Review Article

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Food & Function? Then why not submit to us today or alternatively email us with your suggestions.

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Catabolism of grape juice

Glass of grape juice and a bunch of grapesPolyphenol compounds have previously been shown to have many health benefits including anticancer activity. However, the role of colonic microbiota in degrading dietary polyphenols is attracting great interest due to the potential health benefits associated with the bioactive catabolites (substances produced during destructive metabolism) absorbed into the circulatory system.

In this work, Alan Crozier and colleagues from Glasgow, UK, have investigated the aromatic compounds that result from colonic catabolism of Concord grape juice using an in vitro model of colonic fermentation. After consuming the grape juice substantial quantities of (poly)phenolic compounds reach the large intestine, where they are degraded to bioactive phenolic acids and aromatic compounds, which pass through the circulatory system before being excreted in the urine. The in vivo fate of these catabolites following absorption in the colon was also investigated by GC-MS. It was found that 40% of ingested (poly)phenolic compounds in Concord grape juice pass from the small to the large intestine and contributes to the increased bioavailabilty of the Concord grape polyphenolics.

To read the full article for free until the 1st November, please click the link below:

Colonic catabolism of dietary phenolic and polyphenolic compounds from Concord grape juice, Angelique Stalmach, Christine A. Edwards, Jo Lynne D. Wightman and Alan Crozier, Food Funct., 2012, DOI: 10.1039/c2fo30151b

You can keep up to date with the latest developments from Food & Function by signing up for free table of contents alerts and monthly e-newsletters.

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