Turning natural cofactors into new anti-proliferative agents

07 Dec 2012

This article is HOT as recommended by the referees. And we’ve made it free to access for 4 weeks.

Vitamin B12 plays an important role in the metabolism of many organisms, particularly mammals. Since efficient delivery of vitamin B12 into cells has potential applications in medical therapies, Zelder et al. are sure to inspire wider interest in the design, chemistry and biology of backbone modified B12 derivatives with this hot Perspective.